The lateral prefrontal cortex 🧠— which we think of as critical for goal driven behavior + is a target for psychiatric treatments— is fundamentally different in individuals relative to the group averages we’ve often studied.

👇see preprint and thread, led by Zach Ladwig
#neuroskyence #PsychSciSky

I still get chills

Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts

Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE

see videos, read paper, follow thread
doi.org/10.31234/osf...

Excited to share my first preprint investigating the feasibility and reliability of using precision RSFC in people with Parkinson’s disease! 🧠👇
📄: go.illinois.edu/PDfeasibility

🧵 Thread ⬇️ 1/12

While the world burns, we cook up a new preprint! doi.org/10.1101/2025...

Biophysical modeling is a key tool to derive mechanistic insights into the brain. These models are governed by biologically meaningful parameters (unlike artificial neural networks), but the dirty secret ... 1/N

Spanning spatial scales with functional imaging in the human brain; initial experiences at 10.5 Tesla https://www.biorxiv.org/content/10.1101/2024.12.20.629800v1

📅 New lab review article in Trends in Cognitive Sciences, led by @hyejinjadelee.bsky.social with allydworetsky.bsky.social, & @laboranathan.bsky.social
Check it out here: go.illinois.edu/ticsReview
#neuroskyence #PsychSciSky #Neuroimaging #neuroscience
🧵below...

1) @laboranathan.bsky.social is presenting poster *299.15*.

Nathan’s project uses a large precision fMRI dataset to examine how error signals differ across subjects and tasks, with a special focus on the cingulo-opercular and fronto-parietal brain networks