MOSAIC Group / Sbalzarini Lab
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mosaicgroup.bsky.social
MOSAIC Group / Sbalzarini Lab
@mosaicgroup.bsky.social
We advance scientific computing, machine learning, and AI for the life sciences. We are at the @csbdresden.bsky.social, jointly with @mpi-cbg.de and @tudresden.bsky.social. Posts by Ivo Sbalzarini. https://sbalzarini-lab.org
Modeling spatial point patterns from noisy, incomplete experimental data just got easier! Great work by @domsturm.bsky.social for sparse, noise-robust model inference of point processes 🤩 @tudresden.bsky.social @csbdresden.bsky.social @mpi-cbg.de Preprint out now: arxiv.org/abs/2510.25550
Robust variable selection for spatial point processes observed with noise
We propose a method for variable selection in the intensity function of spatial point processes that combines sparsity-promoting estimation with noise-robust model selection. As high-resolution spatia...
arxiv.org
November 5, 2025 at 4:30 PM
🤩👍🏼💪🏼 Meet #TopoSPAM - a high-performance simulation platform for biological morphogenesis with a friendly Python interface. @tudresden.bsky.social @csbdresden.bsky.social @mpi-cbg.de. Solve both continuous and discrete active mechanics! Released today: arxiv.org/abs/2509.24905
TopoSPAM: Topology grounded Simulation Platform for morphogenesis and biological Active Matter
We present a topology grounded, multiscale simulation platform for morphogenesis and biological active matter. Morphogenesis and biological active matter represent keystone problems in biology with ad...
arxiv.org
October 1, 2025 at 10:21 AM
🤩🤩🤩Absolutely thrilled our work is featured in the Magazine of @maxplanck.de ! Big thanks to the writer and editor 🙏🙏🙏 Never saw our work described so well! Curious? @csbdresden.bsky.social @tudresden.bsky.social @mpi-cbg.de - PDF is freely available, article starts p.36: www.mpg.de/25430399/MPR...
www.mpg.de
September 26, 2025 at 6:49 AM
In a beautiful team effort, we wrote a comprehensive review of meshfree collocation methods for numerically solving PDEs @csbdresden.bsky.social @uni.lu #CVUTPrague @tudresden.bsky.social Preprint out now: arxiv.org/abs/2509.20056
An Overview of Meshfree Collocation Methods
We provide a comprehensive overview of meshfree collocation methods for numerically approximating differential operators on continuously labeled unstructured point clouds. Meshfree collocation methods...
arxiv.org
September 25, 2025 at 3:25 PM
It was a pleasure to speak at #BuildingBridges2025. Germany, Poland, Hungary, and Lithuania - together in one session on #Biomedical #AI. Great also to meet so many friends again!

Big thanks to the organizers for inviting me! 🙏🙏🙏🙏

@hzdr.bsky.social
@tudresden.bsky.social
September 12, 2025 at 12:37 PM
🙏 Very honored to speak at #BuildingBridges2025 on #AI for #Biomedicine. What an amazing lineup of panelists 🤩🤩🤩 Politics and Science working together- Germany, Lithuania, Czech Republic, Poland - together for future #AI 👍🏼 @hzdr.bsky.social @csbdresden.bsky.social
September 12, 2025 at 9:30 AM
Looking forward to present on the topic of AI for Biomedicine tomorrow!
The Building Bridges Conference 2025: Latest Findings in Artificial Intelligence kicked off today, bringing together researchers, policymakers and industry leaders from across Europe. #BuildingBridges2025
September 11, 2025 at 7:27 PM
Reposted by MOSAIC Group / Sbalzarini Lab
#GoGAIN25: 🌎 From August 29 to 31, #TUDresden will be in #Boston with @daadworldwide.bsky.social, @humboldt-foundation.de & @dfg.de, presenting a series of talks & hosting a booth to showcase our University of Excellence & the city of Dresden as a hub for science. 🧑‍🔬
ℹ️ tu-dresden.de/internationa...
August 28, 2025 at 12:29 PM
This👇is fantastic work! Congratulations @loicaroyer.bsky.social and team!!
🧬🔬🧪 🎉 Our team at @czbiohub is thrilled to share TWO companion papers out today in @NatureMethods!
📦 Ultrack — robust, scalable nD cell tracking
🌐 inTRACKtive — a beautiful, open-source web viewer for lineage exploration
Let’s dive in! 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 25, 2025 at 8:07 PM
#GenAI meets perception psychology for better super-resolution microscopy 🤩 Fig.1 says it all! 😎 Fantastic collaboration with @casusscience.bsky.social - work of @zuseschoolsecai.bsky.social students @csbdresden.bsky.social - out now onlinelibrary.wiley.com/doi/10.1002/...
July 24, 2025 at 7:31 PM
🚨Fundamental computer science result! 🤩🤩🤩 Particle Methods, a class of algorithms, can compute anything that is computable, even when severely resource restricted ‼️‼️Formally proven result @csbdresden.bsky.social @tudresden.bsky.social @mpi-cbg.de now out: fi.episciences.org/16055
On the Computational Power of Particle Methods
We investigate the computational power of particle methods, a well-established class of algorit hms with applications in scientific computing and computer simulation. The computational power of a comp...
fi.episciences.org
July 21, 2025 at 8:27 AM
Reposted by MOSAIC Group / Sbalzarini Lab
To learn more about the people behind this work, we caught up with first author Justina Stark, and corresponding authors Ivo Sbalzarini (@mosaicgroup.bsky.social @csbdresden.bsky.social) and Michael Brand (@tudresden.bsky.social):
journals.biologists.com/dev/article/...
July 15, 2025 at 3:29 PM
Reposted by MOSAIC Group / Sbalzarini Lab
Read the #OpenAccess Research Article "Morphogen gradients are regulated by porous media characteristics of the developing tissue" here:
journals.biologists.com/dev/article/...
July 15, 2025 at 3:29 PM
Thanks for the highlight @dev-journal.bsky.social !! 🙏🙏🙏
Mind the pores: studying morphogen gradients

Read this Research Highlight showcasing work from Justina Stark, Rohit Krishnan Harish, Ivo Sbalzarini @mosaicgroup.bsky.social and Michael Brand @tudresden.bsky.social:
journals.biologists.com/dev/article/...
July 15, 2025 at 5:19 PM
⚡️Advanced Computing ❤️ laboratory experiments ➡️ an unbeatable combination to unlock the secrets of biology! Together with the Brand lab @tudresden.bsky.social we @csbdresden.bsky.social discovered a simple mechanism how tissue geometry controls growth: journals.biologists.com/dev/article/...
Morphogen gradients are regulated by porous media characteristics of the developing tissue
Summary: Image-based 3D modeling of pore-scale extracellular space geometries of the developing zebrafish embryo reveals that the Fgf8a morphogen gradient is regulated by the porous media characterist...
journals.biologists.com
July 14, 2025 at 4:45 PM
Our scientific computing framework #OpenFPM now has multistage and adaptive time integrators that scale to distributed CPU clusters and GPUs! Happy supercomputing! @tudresden.bsky.social @csbdresden.bsky.social @mpi-cbg.de preprint: arxiv.org/abs/2309.05331
Integrating Odeint Time Stepping into OpenFPM for Distributed and GPU Accelerated Numerical Solvers
We present a software implementation integrating the time-integration library Odeint from Boost with the OpenFPM framework for scalable scientific computing. This enables compact and scalable codes fo...
arxiv.org
July 10, 2025 at 7:34 AM
🔥🔥🔥Unique opportunity! We are looking for a new Max Planck Director in Biomedical #AI. Max Planck Research Directors enjoy unparalleled freedom and resources. And the best: you’d get to work with us here at the @csbdresden.bsky.social in the heart of the vibrant @tudresden.bsky.social AI campus!
June 26, 2025 at 2:31 PM
Reposted by MOSAIC Group / Sbalzarini Lab
Formulas of Life: article of the @maxplanck.de on the research of Ivo Sbalzarini @mosaicgroup.bsky.social. Article in German language: www.mpg.de/24841408/ki-...
Formeln des Lebens
Künstliche Intelligenz mit physikalischem Vorwissen soll biologische Vorgänge berechenbar machen
www.mpg.de
June 12, 2025 at 8:58 AM
Ivo Sbalzarini was interviewed by German science radio @detektorfm.bsky.social and explains our research @csbdresden.bsky.social @mpi-cbg.de @tudresden.bsky.social to a general audience (in German only):

detektor.fm/wissen/forsc...
Wie kann Künstliche Intelligenz in der Biomedizin helfen?
Biologie und Medizin sind eng verknüpft. Künstliche Intelligenz kann dabei in vielen Fragen helfen. Was ist zu beachten?
detektor.fm
June 12, 2025 at 6:58 AM
🔥Just out @EGPGV’25: Parallel visualization of distributed volume data for non-convex decompositions! @csbdresden.bsky.social @tudresden.bsky.social @mpi-cbg.de And the best: code is contributed upstream 🤩 diglib.eg.org/items/3aed38...
A Transparent and Efficient Extension of IceT for Parallel Compositing on Non-Convex Volume Domain Decompositions
The IceT library is widely used for parallel compositing but does not support non-convex volume domain decompositions. We provide a backward-compatible extension of IceT to handle non-convex domain de...
diglib.eg.org
June 8, 2025 at 9:44 AM
Fantastic! 🤩 Best success ever for our university!! This is going to enable sooooo much cool new research in the coming years. The sky is the limit!
Outstanding success: 🎉 #TUDresden shines with 5 Clusters of Excellence. @dfg.de & @wissenschaftsrat.de announced that decision today. TUD has impressively proven its claim to be a top university for the 21st century.
ℹ️ tu-dresden.de/tu-dresden/n...
May 23, 2025 at 7:59 AM
Proud and happy our group could be involved in this. Congratulations, Roua!
Revisions were a crazy ride & would never have been possible without the endless efforts by @cryaaa.bsky.social & Alba, as well as all the new collaborators that helped with experiments and modelling: Roua Rouatbi @mosaicgroup.bsky.social @csbdresden.bsky.social, Kathrin Schmeisser @ Rodenfels lab
snoop dogg is wearing a suit and tie and eating a fork with the word teamwork written next to him .
ALT: snoop dogg is wearing a suit and tie and eating a fork with the word teamwork written next to him .
media.tenor.com
April 17, 2025 at 9:57 AM
Reposted by MOSAIC Group / Sbalzarini Lab
APR-CNN: Convolutional Neural Networks for the Adaptive Particle Representation of Large Microsco...

Joel Jonsson, Bevan Leslie Cheeseman, Ivo Sbalzarini

Action editor: Moshe Eliasof

https://openreview.net/forum?id=5qKI2dkrjL

#cnn #cnns #microscopy
March 8, 2025 at 3:07 PM
It was great hosting and meeting Sophie Jaffard @csbdresden.bsky.social @tudresden.bsky.social. We look forward to many more discussions on the mathematics of neural networks in neuroscience and in machine learning!
And Sophie Jaffard, also a PhD student from the Université Côte d’Azur in Nice visited Türkü Özlem Çelik and @mosaicgroup.bsky.social to discuss her work on mathematical models of biologically inspired neural networks 🧠
February 28, 2025 at 6:39 PM