New preprint from @morielab.bsky.social: tardigrades are super resistant to DNA insult, yet are not immortal. We asked: why & how do they die? We have discovered their Achilles’ heel! Check it to know (spoiler: it has to do of course with DNA… but also lipids!! 😍)

www.biorxiv.org/cgi/content/...

Xmas-filtered fatty genome view of @morielab.bsky.social as drawn by @JanelieGraphism (X) and pictured by @artigas_quiroga (X).

@carogoujon.bsky.social & @morielab.bsky.social very proudly present the outcome of their collaboration: SARS-CoV-2 exploits Golgi-bound PI4P for its amplification, displacing the DNA damage response master kinase ATM, which becomes massively activated in the cytoplasm doi.org/10.1101/2024...