Mark Lambie
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mlambie.bsky.social
Mark Lambie
@mlambie.bsky.social
850 followers 360 following 3 posts
Nephrologist, especially dialysis, especially at home, and clinical studies about these things
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Reposted by Mark Lambie
er-goffin.bsky.social
Really interesting ; this study emphasises the influence of genetic variants to explain the great inter-individual variability of ultrafiltration in Peritoneal Dialysis patients even at PD onset together with the emerging role of peritoneal adipocytes and prostaglandins in peritoneal physiology 👏👏👏
July 17, 2025 at 3:47 PM
mlambie.bsky.social
journals.lww.com/jasn/abstrac... Great work led by @rajmehrotra.bsky.social substantially improving our understanding of UF in PD
Genetic Variation and Ultrafiltration with Peritoneal... : Journal of the American Society of Nephrology
tration and explored one mechanistic pathway identified by genetic studies. Methods: We generated estimates of heritability and undertook genome-wide and gene-wise studies, adjusted for peritoneal ...
journals.lww.com
July 17, 2025 at 7:49 AM
Reposted by Mark Lambie
johannmorelle.bsky.social
Will Xylocore® be the magic ELIXIR for peritoneal dialysis?

@ispd.org @pdi-journal.bsky.social @drnikhilshah.bsky.social @pd-perls.bsky.social @mlambie.bsky.social

Editorial: journals.sagepub.com/eprint/ENYAN...

Original article: journals.sagepub.com/doi/10.1177/...
January 31, 2025 at 6:23 AM
Reposted by Mark Lambie
ukkidney.org
Upcoming highlights in Advanced Kidney Care...

✅ AKC Symposium 2025
27 February, London
bit.ly/3ZTMXFt

✅ AKC Summit 2025
25 March, Birmingham
bit.ly/49GOl1v

✅ Transform AKC Programme
www.ukkidney.org/about-us/new...
January 7, 2025 at 12:54 PM
Reposted by Mark Lambie
niakhaleenkeita.bsky.social
💥Conakry PD Workshop

Insert PD catheter to manage AKI complications is crucial where indications are not lacking. Training to save (young) lives is essential

@sosendt.bsky.social @er-goffin.bsky.social @ispd1.bsky.social @theisn.org @sfndt.bsky.social
January 15, 2025 at 8:59 PM
Reposted by Mark Lambie
kidneycareuk.bsky.social
The National Institute for Health and Care Excellence has recommended a new treatment called Vadadustat as an option for treating anaemia caused by chronic kidney disease in adults on dialysis. You can find out more about this here: kidneycareuk.org/news-from-ki...
New treatment recommended for anaemia in adults on dialysis
The National Institute for Health and Care Excellence have recommended a new treatment called Vadadustat as an option for treating anaemia caused by chronic kidney disease in adults on dialysis.
kidneycareuk.org
December 18, 2024 at 8:13 PM
Reposted by Mark Lambie
boghuma.bsky.social
Wow just wow. I did not have on my bingo card an mRNA therapeutic for treating pre eclampsia. A VEGF tropic mRNA resolved maternal hypertension until pregnancy in a mouse model of the condition. Really fascinating science.
🧪
www.nature.com/articles/s41...
Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia - Nature
A platform for mRNA lipid nanoparticle delivery to the placenta to treat pre-eclampsia is shown to improve fetal and maternal health in mice and has potential clinical applications in obstetric d...
www.nature.com
December 12, 2024 at 12:52 PM
Reposted by Mark Lambie
swissnephro.bsky.social
1/5 The #SWEETSTONE results were presented at the Swiss Society of Nephrology meeting:

Impact of #empagliflozin on urinary supersaturations in kidney stone formers.
Randomised, double-blind, placebo-controlled, cross-over trial.

#nephsky #nephrolithiasis #flozinator
December 8, 2024 at 1:43 PM
Reposted by Mark Lambie
bonnaud-dowell.bsky.social
I guess this answers the question : pubmed.ncbi.nlm.nih.gov/27890698/
November 29, 2024 at 11:19 AM
Reposted by Mark Lambie
sunilbadve.bsky.social
Sharing the free access link here (for 50 days only) authors.elsevier.com/a/1k9u77tNuc...
November 26, 2024 at 3:39 AM
Reposted by Mark Lambie
kireports.bsky.social
1/
Hello, #NephSky!
Excited to share a 🆕 #Skeetorial on Automated Peritoneal Dialysis (APD) as a modality for Urgent Start Dialysis!
Brought to you by the fantastic team at @kireports.bsky.social Let's dive in! #skeetorial
November 25, 2024 at 4:15 PM
Reposted by Mark Lambie
ispd.org
We just added to www.ispd.org/guidelines the German translation for our ISPD 2022 Peritonitis Guidelines.

We thank Dr V. Schwenger for making these important guidelines available beyond language barriers.

Wanna help us translate ISPD guidelines? Please DM us for more info.
November 25, 2024 at 3:21 PM
Reposted by Mark Lambie
drmarthagulati.bsky.social
@TheLancet session at #AHA24 starting now! #obesity
🫀Malnutrition was a problem but now obesity is taking over worldwide with few exceptions
🫀Severe obesity has also ⤴️
🫀BMI doesn’t reflect obesity as well as waist-to-height ratio
🫀⤴️ diabetes follows obesity
November 16, 2024 at 7:47 PM
Reposted by Mark Lambie
erictopol.bsky.social
We've already seen remarkable results for lupus and other autoimmune diseases with CD19 B cell depletion therapy. Now add IgG4 related disease (which has no treatment) in a new randomized trial
nejm.org/doi/full/10....
Inebilizumab for Treatment of IgG4-Related Disease | NEJM
IgG4-related disease is a multiorgan, relapsing, fibroinflammatory, immune-mediated disorder with no approved therapy. Inebilizumab targets and depletes CD19+ B cells and may be effective for treat...
nejm.org
November 14, 2024 at 3:15 PM
Reposted by Mark Lambie
cardioobdoc.bsky.social
#Tirzepatide for Obesity Treatment & Diabetes Prevention
SURMOUNT-1 Trial

✅ Reduced progression to T2DM by 93%
#CardioSky #EndoSky #MedSky #NEJM
www.nejm.org/doi/full/10....
Tirzepatide for Obesity Treatment and Diabetes Prevention | NEJM
Obesity is chronic disease and causal precursor to myriad other conditions, including type 2 diabetes. In an earlier analysis of the SURMOUNT-1 trial, tirzepatide was shown to provide substantial a...
www.nejm.org
November 14, 2024 at 3:44 AM