mkjoshibmb.bsky.social
@mkjoshibmb.bsky.social
Postdoc @Iovino_Lab @mpi_ie
Former: PhD @ Royet lab @IBDMmarseille.
JRF @tinalab_inStem
Interest: Epigenetics inheritance of environmental stresses
Former: PhD @ Royet lab @IBDMmarseille.
JRF @tinalab_inStem
Interest: Epigenetics inheritance of environmental stresses
Reposted by mkjoshibmb.bsky.social
A little late to share, but still thrilled 🤗!
What started as two independent stories, one in Clermont-Ferrand (@igred.fr) and one in Cambridge (Hannon’s group @cruk-mi.bsky.social ), turned into a joint adventure to decode how Rhino picks its favorite piRNA clusters.
When forces unite…
👇👇👇
What started as two independent stories, one in Clermont-Ferrand (@igred.fr) and one in Cambridge (Hannon’s group @cruk-mi.bsky.social ), turned into a joint adventure to decode how Rhino picks its favorite piRNA clusters.
When forces unite…
👇👇👇
New online: Binding of heterochromatin protein Rhino to a subset of piRNA clusters depends on a combination of two histone marks
Binding of heterochromatin protein Rhino to a subset of piRNA clusters depends on a combination of two histone marks
Nature Structural & Molecular Biology, Published online: 17 June 2025; doi:10.1038/s41594-025-01584-8The authors reveal that, in fruit fly ovaries, the protein Rhino is guided to specific regions of the genome by a combination of two histone modifications, enhancing understanding of how cells protect their DNA from harmful virus-like elements.
go.nature.com
July 2, 2025 at 3:09 PM
A little late to share, but still thrilled 🤗!
What started as two independent stories, one in Clermont-Ferrand (@igred.fr) and one in Cambridge (Hannon’s group @cruk-mi.bsky.social ), turned into a joint adventure to decode how Rhino picks its favorite piRNA clusters.
When forces unite…
👇👇👇
What started as two independent stories, one in Clermont-Ferrand (@igred.fr) and one in Cambridge (Hannon’s group @cruk-mi.bsky.social ), turned into a joint adventure to decode how Rhino picks its favorite piRNA clusters.
When forces unite…
👇👇👇
Reposted by mkjoshibmb.bsky.social
New research from EMBL Rome shows how paternal environment prior to conception can shape early embryo development.
These findings are a step toward understanding the mechanism of epigenetic inheritance, opening up new possibilities for disease prevention.
www.embl.org/news/science...
These findings are a step toward understanding the mechanism of epigenetic inheritance, opening up new possibilities for disease prevention.
www.embl.org/news/science...
September 30, 2025 at 6:55 AM
New research from EMBL Rome shows how paternal environment prior to conception can shape early embryo development.
These findings are a step toward understanding the mechanism of epigenetic inheritance, opening up new possibilities for disease prevention.
www.embl.org/news/science...
These findings are a step toward understanding the mechanism of epigenetic inheritance, opening up new possibilities for disease prevention.
www.embl.org/news/science...
Reposted by mkjoshibmb.bsky.social
This is such a cool paper. Heritable transgenerational inheritance of polycomb silencing in flies (no DNA methylation!).
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
Interchromosomal contacts between regulatory regions trigger stable transgenerational epigenetic inheritance in Drosophila
In some cases, non-genetic information can be inherited across generations. Fitz-James et al. investigate the mechanism by which such epigenetic information becomes heritable in fruit flies. They show that physical contact between regions of DNA within the cell is able to trigger the histone modification H3K27me3 to become heritable.
www.cell.com
December 12, 2024 at 10:10 PM
This is such a cool paper. Heritable transgenerational inheritance of polycomb silencing in flies (no DNA methylation!).
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...