Stephen Mihalcik
@mihalcikradonc.bsky.social
Reposted by Stephen Mihalcik
Reposted by Stephen Mihalcik
Interesting paper from Subramani et al. showing that Marburg vaccines are more effective when they incorporate GP only. Seems like "GP-immunofocusing" is critical, particularly at low vaccine doses.
When more isn’t better: The surprising superiority of glycoprotein-only Marburg vaccines: buff.ly/NK3Pmlf
An Editor’s Note by @pemac.bsky.social @harvardmed.bsky.social on Subramani et al. (buff.ly/y6LTOo3)
An Editor’s Note by @pemac.bsky.social @harvardmed.bsky.social on Subramani et al. (buff.ly/y6LTOo3)
September 12, 2025 at 11:48 AM
Interesting paper from Subramani et al. showing that Marburg vaccines are more effective when they incorporate GP only. Seems like "GP-immunofocusing" is critical, particularly at low vaccine doses.
Reposted by Stephen Mihalcik
Postdoc and Staff Scientist positions in the Penaloza-MacMaster lab at BIDMC.
November 14, 2025 at 5:36 PM
Postdoc and Staff Scientist positions in the Penaloza-MacMaster lab at BIDMC.
Reposted by Stephen Mihalcik
Is one vaccine platform superior to another?
Here, Pablo Penaloza-MacMaster @pemac.bsky.social & team performed a side-by-side comparison of adenovirus, mRNA, and protein vaccines in mice, revealing vaccine performance is shaped by context: insight.jci.org/articles/vie...
Here, Pablo Penaloza-MacMaster @pemac.bsky.social & team performed a side-by-side comparison of adenovirus, mRNA, and protein vaccines in mice, revealing vaccine performance is shaped by context: insight.jci.org/articles/vie...
November 19, 2025 at 2:03 PM
Is one vaccine platform superior to another?
Here, Pablo Penaloza-MacMaster @pemac.bsky.social & team performed a side-by-side comparison of adenovirus, mRNA, and protein vaccines in mice, revealing vaccine performance is shaped by context: insight.jci.org/articles/vie...
Here, Pablo Penaloza-MacMaster @pemac.bsky.social & team performed a side-by-side comparison of adenovirus, mRNA, and protein vaccines in mice, revealing vaccine performance is shaped by context: insight.jci.org/articles/vie...
Interesting paper comparing different vaccine platforms!
Is one vaccine platform superior to another?
Here, Pablo Penaloza-MacMaster @pemac.bsky.social & team performed a side-by-side comparison of adenovirus, mRNA, and protein vaccines in mice, revealing vaccine performance is shaped by context: insight.jci.org/articles/vie...
Here, Pablo Penaloza-MacMaster @pemac.bsky.social & team performed a side-by-side comparison of adenovirus, mRNA, and protein vaccines in mice, revealing vaccine performance is shaped by context: insight.jci.org/articles/vie...
November 20, 2025 at 1:26 AM
Interesting paper comparing different vaccine platforms!