Margarida Gama-Carvalho
@mgama.bsky.social
Academic Scientist - RNA Systems Biology Lab 🧬University of Lisbon 🇵🇹 Lover of big pictures & small details CP artist Citizen of the 🌎
After 1h without power this is getting scary 🫣
Spain, Portugal and other European countries have been hit with a major power outage.
April 28, 2025 at 11:27 AM
After 1h without power this is getting scary 🫣
Anyone else unable to run NCBI blast right now?
March 18, 2025 at 3:26 PM
Anyone else unable to run NCBI blast right now?
1/ The thymus is essential for T-cell maturation, protecting us from pathogens while ensuring tolerance to our own tissues. 🧬 This balance is maintained by the thymic epithelium, which, in mammals, birds, and bony fish, develops from the 3rd/4th pharyngeal pouches during embryogenesis.
December 6, 2024 at 7:22 PM
1/ The thymus is essential for T-cell maturation, protecting us from pathogens while ensuring tolerance to our own tissues. 🧬 This balance is maintained by the thymic epithelium, which, in mammals, birds, and bony fish, develops from the 3rd/4th pharyngeal pouches during embryogenesis.
Reposted by Margarida Gama-Carvalho
Apesar de tantas promessas (ver imagem), o orçamento da FCT não só não cresceu como até diminuiu em %PIB
Q isto não aconteça ao abrigo do nosso silêncio
Escrevam aos deputad@s, pedindo para q votem favoravelmente a única proposta específica de aumento deste valor
1/ app.parlamento.pt/webutils/doc...
Q isto não aconteça ao abrigo do nosso silêncio
Escrevam aos deputad@s, pedindo para q votem favoravelmente a única proposta específica de aumento deste valor
1/ app.parlamento.pt/webutils/doc...
November 22, 2024 at 10:49 AM
Apesar de tantas promessas (ver imagem), o orçamento da FCT não só não cresceu como até diminuiu em %PIB
Q isto não aconteça ao abrigo do nosso silêncio
Escrevam aos deputad@s, pedindo para q votem favoravelmente a única proposta específica de aumento deste valor
1/ app.parlamento.pt/webutils/doc...
Q isto não aconteça ao abrigo do nosso silêncio
Escrevam aos deputad@s, pedindo para q votem favoravelmente a única proposta específica de aumento deste valor
1/ app.parlamento.pt/webutils/doc...
Giving junior team members the freedom to choose their lab-meeting topic just resulted in a refreshing afternoon discussion of the Better Science Initiative. A chance to talk about many important things for their wellbeing and future and overall a great team building moment 🧬
November 20, 2024 at 10:13 PM
Giving junior team members the freedom to choose their lab-meeting topic just resulted in a refreshing afternoon discussion of the Better Science Initiative. A chance to talk about many important things for their wellbeing and future and overall a great team building moment 🧬
Really cool work on immunoribosomes!
Ribosomes are heterogenous and long believed immunoribosome revealed by this study that P-Stalk ribosome responds to inflammatory cues and alert 🚨 cell immune response.
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
P-stalk ribosomes act as master regulators of cytokine-mediated processes
Cytokines remodel the ribosome to incorporate the P-stalk, therefore altering the
translation of mRNAs involved in cytokine responses.
www.cell.com
November 18, 2024 at 9:53 PM
Really cool work on immunoribosomes!
Great to see the science community growing here 😊
My first post on Blue Sky - moving over !
For all post-docs out there - fantastic opportunity @EMBL. Independent group leader position: Core funding, state-of-the-art core facilities, access to fantastic Ph.D. students, and of course amazing colleagues. Please apply www.embl.org/jobs/positio...
For all post-docs out there - fantastic opportunity @EMBL. Independent group leader position: Core funding, state-of-the-art core facilities, access to fantastic Ph.D. students, and of course amazing colleagues. Please apply www.embl.org/jobs/positio...
EMBL Jobs
We offer a wide range of challenging scientific and non-scientific positions at all of our European locations and encourage applications from international candidates at all career levels.
www.embl.org
November 18, 2024 at 9:47 PM
Great to see the science community growing here 😊
Excited to be in this amazing line up for the RNA biology in host-pathogen interactions conference organized by the EpiViral twinning project! Plus in beautiful Porto! 🧬🔬🧫
January 29, 2024 at 1:14 AM
Excited to be in this amazing line up for the RNA biology in host-pathogen interactions conference organized by the EpiViral twinning project! Plus in beautiful Porto! 🧬🔬🧫
Just read an interesting piece based on this study (psycnet.apa.org/doi/10.1037/...) suggesting that the common advice about using humor to make presentations more engaging may backfire on women. It kind of aligns with my personal experience with students. Anyone else?
January 2, 2024 at 10:06 PM
Just read an interesting piece based on this study (psycnet.apa.org/doi/10.1037/...) suggesting that the common advice about using humor to make presentations more engaging may backfire on women. It kind of aligns with my personal experience with students. Anyone else?
Reposted by Margarida Gama-Carvalho
bioRxiv goes big on Bluesky: accounts for all subject categories now available (Please Reskeet) connect.biorxiv.org/news/2023/09...
September 28, 2023 at 2:27 PM
bioRxiv goes big on Bluesky: accounts for all subject categories now available (Please Reskeet) connect.biorxiv.org/news/2023/09...
Reposted by Margarida Gama-Carvalho
mRNA for the win! #RNASky #RNAbiology
Some great news to end the year - Moderna’s mRNA skin cancer vaccine stops recurrence in 49% of people who receive it up to 3 years after treatment. The first stage of a revolution in cancer treatment. (h/t IFP)
December 28, 2023 at 10:44 PM
mRNA for the win! #RNASky #RNAbiology
Reposted by Margarida Gama-Carvalho
If there is anybody on Bluesky with an interest in working towards a PhD with a vibrant and inclusive group of people, we have a funded project available through @singmolsci.bsky.social in UNSW, Sydney, to do some advanced single molecule & electron 🔬. Please pass on to any students you may know. 🧪
Molecular scale mapping of intracellular signalling nanodomains and giant channels in the heart
www.unsw.edu.au
November 21, 2023 at 10:53 PM
If there is anybody on Bluesky with an interest in working towards a PhD with a vibrant and inclusive group of people, we have a funded project available through @singmolsci.bsky.social in UNSW, Sydney, to do some advanced single molecule & electron 🔬. Please pass on to any students you may know. 🧪
On the good side of the news 🇵🇹
“A complete nightmare for consumers” according to Oil and Gas employees 😂.
6 days of free electricity and zero carbon emissions in Portugal
6 days of free electricity and zero carbon emissions in Portugal
Portugal Runs on 100% Renewables Dropping Consumer Electric Bills to Nearly Zero for 6 Days in a Row
In total, there were 149 hours of total renewables generation, 95 of which saw the Portuguese grid exporting to Spain
www.goodnewsnetwork.org
November 27, 2023 at 12:47 AM
On the good side of the news 🇵🇹
A little secret about me… this is how I unwind in the evening. Drawing (preferably) furry canine creatures with color pencils. This one is already some 6-8h of work, 10x to go before finished.
November 26, 2023 at 1:52 AM
A little secret about me… this is how I unwind in the evening. Drawing (preferably) furry canine creatures with color pencils. This one is already some 6-8h of work, 10x to go before finished.
When your institution has a core research line on grapevine biology it’s really easy to come up with a #SciCom activity that makes people happy to sit down for a couple of hours listening to science topics! A toast to our 6th Science and Technology Week wine tasting event 🥂
November 25, 2023 at 7:59 PM
When your institution has a core research line on grapevine biology it’s really easy to come up with a #SciCom activity that makes people happy to sit down for a couple of hours listening to science topics! A toast to our 6th Science and Technology Week wine tasting event 🥂
Reposted by Margarida Gama-Carvalho
Pandemic-related immunity gap in kids explains surge of respiratory infections in children in China, says WHO
Pandemic-related immunity gap in kids explains surge of respiratory infections in children in China,...
In a Q&A, the acting director of the WHO’s department of epidemic and pandemic preparedness and prevention explains why worries about respiratory infections in China are overblown.
www.statnews.com
November 25, 2023 at 8:46 AM
Pandemic-related immunity gap in kids explains surge of respiratory infections in children in China, says WHO
Super chuffed to see my oldest MSc student finally graduate with a top mark 🥰 Daniel is an example of persistence in the face of adversity (cancer, a pandemic, full time job for subsistence) always with a smile and genuine love for science. Part of his work is here: doi.org/10.1186/s129...
Human Satellite 1A analysis provides evidence of pericentromeric transcription - BMC Biology
Background Pericentromeric regions of human chromosomes are composed of tandem-repeated and highly organized sequences named satellite DNAs. Human classical satellite DNAs are classified into three fa...
doi.org
November 23, 2023 at 12:42 PM
Super chuffed to see my oldest MSc student finally graduate with a top mark 🥰 Daniel is an example of persistence in the face of adversity (cancer, a pandemic, full time job for subsistence) always with a smile and genuine love for science. Part of his work is here: doi.org/10.1186/s129...
A rare moment with a pressing excuse to get my hands dirty and show my team I still have the touch: receiving live human cells shipped by my collaborator 300km away to have the DNA extracted on site for ultra-long read genome sequencing at our facility. PIs: do you still manage to do lab stuff? 🧬
November 21, 2023 at 12:04 PM
A rare moment with a pressing excuse to get my hands dirty and show my team I still have the touch: receiving live human cells shipped by my collaborator 300km away to have the DNA extracted on site for ultra-long read genome sequencing at our facility. PIs: do you still manage to do lab stuff? 🧬
Reposted by Margarida Gama-Carvalho
HOORAY!!!!
FlyBase is now on Bluesky!
November 20, 2023 at 7:11 PM
HOORAY!!!!
When you are asked to sign off on a 15k budget to repair your old Calibur after the rep has taken a look at the problem and decide you will try to figure it out yourself… to find a single cable is disconnected inside. This is the real resuscitation miracle 😅 (ok, credits go to my geek son)
November 20, 2023 at 7:49 PM
When you are asked to sign off on a 15k budget to repair your old Calibur after the rep has taken a look at the problem and decide you will try to figure it out yourself… to find a single cable is disconnected inside. This is the real resuscitation miracle 😅 (ok, credits go to my geek son)
Reposted by Margarida Gama-Carvalho
I'm once again trying to break ties with the bird site. How hard is it going to be to rebuild my network here on bsky?🤔
November 18, 2023 at 4:15 PM
I'm once again trying to break ties with the bird site. How hard is it going to be to rebuild my network here on bsky?🤔
Reposted by Margarida Gama-Carvalho
Been a while since we've had a really really bad SARS-CoV-2 preprint, and right on cue....
Human microbiota is a reservoir of SARS-CoV-2 advantageous mutations https://www.biorxiv.org/content/10.1101/2023.11.16.567485v1
Human microbiota is a reservoir of SARS-CoV-2 advantageous mutations https://www.biorxiv.org/content/10.1101/2023.11.16.567485v1
SARS-CoV-2 mutations are rapidly emerging, in particular advantageous mutations in the spike (S) pro
www.biorxiv.org
November 18, 2023 at 4:40 PM
Been a while since we've had a really really bad SARS-CoV-2 preprint, and right on cue....
#Weekend post: gardener me thinks she is now the victim of something she found out about in a paper 😭 doi.org/10.1007/s12600-021-00903-1
November 19, 2023 at 2:17 PM
#Weekend post: gardener me thinks she is now the victim of something she found out about in a paper 😭 doi.org/10.1007/s12600-021-00903-1
Nice day with the 🇵🇹 genomics community at the GenomePT annual symposium, brilliantly organized by the 🇵🇹 National Health Institute consortium node. The rise of genomics for One Health is a sight to see, beautifully capped off by an amazing talk on the human pangenome by @aphillippy.bsky.social 👏👏
November 17, 2023 at 7:13 PM
Nice day with the 🇵🇹 genomics community at the GenomePT annual symposium, brilliantly organized by the 🇵🇹 National Health Institute consortium node. The rise of genomics for One Health is a sight to see, beautifully capped off by an amazing talk on the human pangenome by @aphillippy.bsky.social 👏👏
Am I the only one who can’t suffer fools who don’t understand the proper use of “reply to all” in department/working group e-mails?? Is it really THAT hard?? 🤦♀️🤦♀️🤦♀️
November 15, 2023 at 10:41 PM
Am I the only one who can’t suffer fools who don’t understand the proper use of “reply to all” in department/working group e-mails?? Is it really THAT hard?? 🤦♀️🤦♀️🤦♀️