Wouter Meuleman
@meuleman.bsky.social
Affiliate Associate Professor @ UW.
Previously @ Altius Institute (Principal Investigator), @csail.mit.edu (postdoc), @nkinl.bsky.social / @tudelfteemcs.bsky.social (PhD).
Loves a good analogy!
Previously @ Altius Institute (Principal Investigator), @csail.mit.edu (postdoc), @nkinl.bsky.social / @tudelfteemcs.bsky.social (PhD).
Loves a good analogy!
Reposted by Wouter Meuleman
🚀Excited to share our new preprint: “Programming human cell type-specific gene expression via an atlas of AI-designed enhancers”
We built the largest repository of AI-designed enhancers, validated across 10 human cell lines + mouse retina.
👉 www.biorxiv.org/content/10.1...
#AI #Genomics #SynBio
We built the largest repository of AI-designed enhancers, validated across 10 human cell lines + mouse retina.
👉 www.biorxiv.org/content/10.1...
#AI #Genomics #SynBio
Programming human cell type-specific gene expression via an atlas of AI-designed enhancers
Differentially active enhancers are key drivers of cell type specific gene expression. Active enhancers are found in open chromatin, which can be mapped at genome scale across tissue and cell types. T...
www.biorxiv.org
October 6, 2025 at 4:57 PM
🚀Excited to share our new preprint: “Programming human cell type-specific gene expression via an atlas of AI-designed enhancers”
We built the largest repository of AI-designed enhancers, validated across 10 human cell lines + mouse retina.
👉 www.biorxiv.org/content/10.1...
#AI #Genomics #SynBio
We built the largest repository of AI-designed enhancers, validated across 10 human cell lines + mouse retina.
👉 www.biorxiv.org/content/10.1...
#AI #Genomics #SynBio
The best moment to put this out there was 10 years ago, the second best moment is right now :-)
"Epilogos: information-theoretic navigation of multi-tissue functional genomic annotations"
"Epilogos: information-theoretic navigation of multi-tissue functional genomic annotations"
September 10, 2025 at 9:09 AM
The best moment to put this out there was 10 years ago, the second best moment is right now :-)
"Epilogos: information-theoretic navigation of multi-tissue functional genomic annotations"
"Epilogos: information-theoretic navigation of multi-tissue functional genomic annotations"
After nine years at the Altius Institute for Biomedical Sciences, I’ve decided it’s time to move on.
For the past two-plus years I’ve been nine hours ahead in the Netherlands. The calendars usually lined up, but life and sleep rarely did － so I’ve reset the clock.
For the past two-plus years I’ve been nine hours ahead in the Netherlands. The calendars usually lined up, but life and sleep rarely did － so I’ve reset the clock.
July 4, 2025 at 12:18 PM
After nine years at the Altius Institute for Biomedical Sciences, I’ve decided it’s time to move on.
For the past two-plus years I’ve been nine hours ahead in the Netherlands. The calendars usually lined up, but life and sleep rarely did － so I’ve reset the clock.
For the past two-plus years I’ve been nine hours ahead in the Netherlands. The calendars usually lined up, but life and sleep rarely did － so I’ve reset the clock.
New paper out in @cp-cellsystems.bsky.social in collaboration with the lab of Georg Seelig at UW, and led by the awesome Chris Yin and @castillohair.bsky.social
Using a variety of deep-learning models, we design synthetic enhancer elements:
Using a variety of deep-learning models, we design synthetic enhancer elements:
June 19, 2025 at 2:24 PM
New paper out in @cp-cellsystems.bsky.social in collaboration with the lab of Georg Seelig at UW, and led by the awesome Chris Yin and @castillohair.bsky.social
Using a variety of deep-learning models, we design synthetic enhancer elements:
Using a variety of deep-learning models, we design synthetic enhancer elements: