MEPGT
@mepgt.bsky.social
PhD student in Uppsala University and Zhejiang University
Pinned
MEPGT
@mepgt.bsky.social
· 18d
🙌Very important method! I have tested in many plants species and got robust values under kind help of Bastiaan (he is a very nice guy!). Now pulished in Genome Biology
doi.org/10.1186/s130...
ParaMask: identify multicopy genomic regions, corrects major biases in WGS data
github.com/Fulgione-gro...
doi.org/10.1186/s130...
ParaMask: identify multicopy genomic regions, corrects major biases in WGS data
github.com/Fulgione-gro...
Reposted by MEPGT
Pleased to share our latest paper led by @tomlewin.bsky.social, now out in @currentbiology.bsky.social! We present the first chromosome-level genome of a phoronid and show that shared chromosomal fusions unite phoronids and bryozoans as sister groups.
www.cell.com/current-biol...
www.cell.com/current-biol...
November 7, 2025 at 4:21 PM
Pleased to share our latest paper led by @tomlewin.bsky.social, now out in @currentbiology.bsky.social! We present the first chromosome-level genome of a phoronid and show that shared chromosomal fusions unite phoronids and bryozoans as sister groups.
www.cell.com/current-biol...
www.cell.com/current-biol...
Reposted by MEPGT
New publication out, highlighting the link between genetic diversity (GD) and policy! 🧬📜
"Conserving genetic diversity in accordance with the Global Biodiversity Framework"
www.annualreviews.org/content/jour...
We summarize the highlights in this thread. 🧵
"Conserving genetic diversity in accordance with the Global Biodiversity Framework"
www.annualreviews.org/content/jour...
We summarize the highlights in this thread. 🧵
Conserving Genetic and Genomic Diversity in Accordance with the Global Biodiversity Framework
Adopted in December 2022, the Kunming–Montreal Global Biodiversity Framework (KMGBF) under the Convention on Biological Diversity outlines a visionary road map guiding humanity's relationship wit...
www.annualreviews.org
November 9, 2025 at 4:23 PM
New publication out, highlighting the link between genetic diversity (GD) and policy! 🧬📜
"Conserving genetic diversity in accordance with the Global Biodiversity Framework"
www.annualreviews.org/content/jour...
We summarize the highlights in this thread. 🧵
"Conserving genetic diversity in accordance with the Global Biodiversity Framework"
www.annualreviews.org/content/jour...
We summarize the highlights in this thread. 🧵
Reposted by MEPGT
How do GWAS and rare variant burden tests rank gene signals?
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
Specificity, length and luck drive gene rankings in association studies - Nature
Genetic association tests prioritize candidate genes based on different criteria.
www.nature.com
November 7, 2025 at 12:05 AM
How do GWAS and rare variant burden tests rank gene signals?
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
Reposted by MEPGT
. @pnas.org just published the final version of our manuscript on how generation time and effective population size interact to shape vertebrate germline mutation rates, led by Luke Zhu and Annabel Beichman: www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
May 21, 2025 at 7:33 PM
. @pnas.org just published the final version of our manuscript on how generation time and effective population size interact to shape vertebrate germline mutation rates, led by Luke Zhu and Annabel Beichman: www.pnas.org/doi/10.1073/...
Reposted by MEPGT
📣Online NOW!
📄Estimation of demography and mutation rates from one million haploid genomes
🧑🤝🧑 @jgschraiber.bsky.social @jeffspence.github.io @docedge.bsky.social
📄Estimation of demography and mutation rates from one million haploid genomes
🧑🤝🧑 @jgschraiber.bsky.social @jeffspence.github.io @docedge.bsky.social
Estimation of demography and mutation rates from one million haploid genomes
Samples of millions of genomes provide substantial information about recent demography
and mutation, but standard population-genetic methods make assumptions not met in
these data. We introduce DR EVI...
www.cell.com
August 13, 2025 at 2:40 PM
📣Online NOW!
📄Estimation of demography and mutation rates from one million haploid genomes
🧑🤝🧑 @jgschraiber.bsky.social @jeffspence.github.io @docedge.bsky.social
📄Estimation of demography and mutation rates from one million haploid genomes
🧑🤝🧑 @jgschraiber.bsky.social @jeffspence.github.io @docedge.bsky.social
Reposted by MEPGT
Our new @science.org paper is out! Cuckoos and hosts are locked in a coevolutionary arms race over egg mimicry.
But how are these egg types inherited, and could this drive speciation? We sequenced hundreds of genomes to find out!
doi.org/10.1126/scie...
🧵1/6
But how are these egg types inherited, and could this drive speciation? We sequenced hundreds of genomes to find out!
doi.org/10.1126/scie...
🧵1/6
Genomic architecture of egg mimicry and its consequences for speciation in parasitic cuckoos
Host-parasite arms races facilitate rapid evolution and can fuel speciation. Cuculus cuckoos are deceptive egg mimics that exhibit a broad diversity of counterfeit egg phenotypes, representing host-ad...
doi.org
October 30, 2025 at 7:15 PM
Our new @science.org paper is out! Cuckoos and hosts are locked in a coevolutionary arms race over egg mimicry.
But how are these egg types inherited, and could this drive speciation? We sequenced hundreds of genomes to find out!
doi.org/10.1126/scie...
🧵1/6
But how are these egg types inherited, and could this drive speciation? We sequenced hundreds of genomes to find out!
doi.org/10.1126/scie...
🧵1/6
Reposted by MEPGT
Chongyi's paper from the biodiversity exploratories (@bexplo.bsky.social) is finally out ! How do genomic traits interact with community ecology?
Antropogenic
havoc. Communities shake.
Genomes grow and break.
doi.org/10.1111/1365...
Antropogenic
havoc. Communities shake.
Genomes grow and break.
doi.org/10.1111/1365...
Context‐dependent relationships between genomic traits and plant performance in temperate grasslands
Read the free Plain Language Summary for this article on the Journal blog.
doi.org
August 6, 2025 at 7:45 AM
Chongyi's paper from the biodiversity exploratories (@bexplo.bsky.social) is finally out ! How do genomic traits interact with community ecology?
Antropogenic
havoc. Communities shake.
Genomes grow and break.
doi.org/10.1111/1365...
Antropogenic
havoc. Communities shake.
Genomes grow and break.
doi.org/10.1111/1365...
Reposted by MEPGT
The Johri Lab has an open postdoc position. Please send me an email, if interested. Start date is flexible. Please do share! Thank you in advance.
October 28, 2025 at 9:31 PM
The Johri Lab has an open postdoc position. Please send me an email, if interested. Start date is flexible. Please do share! Thank you in advance.
PNAS: When islands collide: Divergence predicts outcomes of secondary contact during the fusion of Sulawesi’s paleo-archipelago, doi.org/10.1073/pnas...
October 28, 2025 at 9:59 AM
PNAS: When islands collide: Divergence predicts outcomes of secondary contact during the fusion of Sulawesi’s paleo-archipelago, doi.org/10.1073/pnas...
Reposted by MEPGT
Hey Yaniv Brandvain is not on Bluesky but his most recent biostats ebook is live ybrandvain.github.io/biostats/. His stats resources have been so helpful to me as I develop my own stats course, so check it out. Github repo here: github.com/ybrandvain/b...
Applied Biostatistics
ybrandvain.github.io
October 24, 2025 at 2:47 PM
Hey Yaniv Brandvain is not on Bluesky but his most recent biostats ebook is live ybrandvain.github.io/biostats/. His stats resources have been so helpful to me as I develop my own stats course, so check it out. Github repo here: github.com/ybrandvain/b...
🙌Very important method! I have tested in many plants species and got robust values under kind help of Bastiaan (he is a very nice guy!). Now pulished in Genome Biology
doi.org/10.1186/s130...
ParaMask: identify multicopy genomic regions, corrects major biases in WGS data
github.com/Fulgione-gro...
doi.org/10.1186/s130...
ParaMask: identify multicopy genomic regions, corrects major biases in WGS data
github.com/Fulgione-gro...
October 24, 2025 at 11:17 AM
🙌Very important method! I have tested in many plants species and got robust values under kind help of Bastiaan (he is a very nice guy!). Now pulished in Genome Biology
doi.org/10.1186/s130...
ParaMask: identify multicopy genomic regions, corrects major biases in WGS data
github.com/Fulgione-gro...
doi.org/10.1186/s130...
ParaMask: identify multicopy genomic regions, corrects major biases in WGS data
github.com/Fulgione-gro...
Reposted by MEPGT
My main PhD work @monteirolab.bsky.social is now in @natecoevo.nature.com! We found a Hox gene promoter that helps butterflies🦋adjust their wing eyespots in response to seasonal temperatures🍃🍂, shedding light on the evolutionary origin of phenotypic plasticity. 1/9 www.nature.com/articles/s41...
October 24, 2025 at 10:16 AM
My main PhD work @monteirolab.bsky.social is now in @natecoevo.nature.com! We found a Hox gene promoter that helps butterflies🦋adjust their wing eyespots in response to seasonal temperatures🍃🍂, shedding light on the evolutionary origin of phenotypic plasticity. 1/9 www.nature.com/articles/s41...
Reposted by MEPGT
Results I'm sad to share but must be told - branching coral are now functionally extinct in Florida - to learn more check out the full study www.science.org/doi/10.1126/... and our personal summary theconversation.com/2-iconic-cor...
Heat-driven functional extinction of Caribbean Acropora corals from Florida’s Coral Reef
In 2023, a record-setting marine heat wave triggered the ninth mass coral bleaching event on Florida’s Coral Reef (FCR). We examined spatial patterns of heat exposure along the ~560-kilometer length o...
www.science.org
October 23, 2025 at 6:26 PM
Results I'm sad to share but must be told - branching coral are now functionally extinct in Florida - to learn more check out the full study www.science.org/doi/10.1126/... and our personal summary theconversation.com/2-iconic-cor...
Reposted by MEPGT
If you like genomics, speciation, and primates, this PhD position is for you! Unraveling the genomic architecture of speciation and gene flow in guenons, a diverse group of African monkeys. Funding through DTP. Do reach out with questions! #genomics #genome_assembly
evol.mcmaster.ca/brian/evoldi...
evol.mcmaster.ca/brian/evoldi...
October 23, 2025 at 3:11 PM
If you like genomics, speciation, and primates, this PhD position is for you! Unraveling the genomic architecture of speciation and gene flow in guenons, a diverse group of African monkeys. Funding through DTP. Do reach out with questions! #genomics #genome_assembly
evol.mcmaster.ca/brian/evoldi...
evol.mcmaster.ca/brian/evoldi...
Reposted by MEPGT
How many plant species are buzz pollinated? After more than six years in the making, our paper on the convergent evolution of buzz pollinated flowers is out in @journal-evo.bsky.social. Thanks @draverbee.bsky.social @roszenil.bsky.social and all co-authors for your hard work! doi.org/10.1093/evol...
October 23, 2025 at 4:50 AM
How many plant species are buzz pollinated? After more than six years in the making, our paper on the convergent evolution of buzz pollinated flowers is out in @journal-evo.bsky.social. Thanks @draverbee.bsky.social @roszenil.bsky.social and all co-authors for your hard work! doi.org/10.1093/evol...
Reposted by MEPGT
Why are some species smaller than a paperclip while others grow longer than a school bus? How is body size evolution governed in animals? Out now in @pnas.org we tackle these longstanding questions through a genetic lens using my favorite group of fishes as our model!! www.pnas.org/doi/10.1073/...
Parallel shifts in differential gene expression reveal convergent miniaturization in fishes | PNAS
Body size variation in vertebrates is a complex polygenic trait, tightly correlated
with numerous aspects of a species’ biology, ecology, and physi...
www.pnas.org
October 22, 2025 at 9:33 PM
Why are some species smaller than a paperclip while others grow longer than a school bus? How is body size evolution governed in animals? Out now in @pnas.org we tackle these longstanding questions through a genetic lens using my favorite group of fishes as our model!! www.pnas.org/doi/10.1073/...
Reposted by MEPGT
Presenting on the important relationship between a project - @biogeneurope.bsky.social - and a community - @ergabiodiv.bsky.social at #LivingData2025
October 22, 2025 at 6:56 PM
Presenting on the important relationship between a project - @biogeneurope.bsky.social - and a community - @ergabiodiv.bsky.social at #LivingData2025
Reposted by MEPGT
Myself and Alastair Wilson wrote an updated version of our 2016 primer to quantitative genetics in the wild: www.sciencedirect.com/science/arti.... Happy to share a copy if interested. It is also on research gate
Quantitative Genetics in Natural Populations
Phenotypes evolve under natural selection if, and only if, they are genetically variable. While evolutionary ecologists have long studied natural sele…
www.sciencedirect.com
October 21, 2025 at 4:31 PM
Myself and Alastair Wilson wrote an updated version of our 2016 primer to quantitative genetics in the wild: www.sciencedirect.com/science/arti.... Happy to share a copy if interested. It is also on research gate
Reposted by MEPGT
Check out our new paper about chromosomal inversions in Malawi cichlids! 🐟🧬
Available here without a paywall: hdl.handle.net/10067/214834... (click on the ‘Full text (open access)’ link).
Available here without a paywall: hdl.handle.net/10067/214834... (click on the ‘Full text (open access)’ link).
June 19, 2025 at 12:23 PM
Check out our new paper about chromosomal inversions in Malawi cichlids! 🐟🧬
Available here without a paywall: hdl.handle.net/10067/214834... (click on the ‘Full text (open access)’ link).
Available here without a paywall: hdl.handle.net/10067/214834... (click on the ‘Full text (open access)’ link).
Nice work! R.M. Schweizer, et a., Museum genomics suggests long-term population decline in a putatively extinct bumble bee, Proc. Natl. Acad. Sci. U.S.A. 122 (43) e2509749122, doi.org/10.1073/pnas... (2025).
October 20, 2025 at 8:50 PM
Nice work! R.M. Schweizer, et a., Museum genomics suggests long-term population decline in a putatively extinct bumble bee, Proc. Natl. Acad. Sci. U.S.A. 122 (43) e2509749122, doi.org/10.1073/pnas... (2025).
Reposted by MEPGT
We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT
October 15, 2025 at 3:53 PM
We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT
Reposted by MEPGT
Out now on the cover of @journal-evo.bsky.social!
Led by Sarah Khalil, we took a genomic approach to investigate the hybrid zone between different-colored Red-backed Fairywren subspecies. We found some interesting candidate genes under selection. Check it out! academic.oup.com/evolut/advan...
Led by Sarah Khalil, we took a genomic approach to investigate the hybrid zone between different-colored Red-backed Fairywren subspecies. We found some interesting candidate genes under selection. Check it out! academic.oup.com/evolut/advan...
October 18, 2025 at 4:42 PM
Out now on the cover of @journal-evo.bsky.social!
Led by Sarah Khalil, we took a genomic approach to investigate the hybrid zone between different-colored Red-backed Fairywren subspecies. We found some interesting candidate genes under selection. Check it out! academic.oup.com/evolut/advan...
Led by Sarah Khalil, we took a genomic approach to investigate the hybrid zone between different-colored Red-backed Fairywren subspecies. We found some interesting candidate genes under selection. Check it out! academic.oup.com/evolut/advan...
Reposted by MEPGT
1/9 New in @science.org www.science.org/doi/10.1126/science.ado8005
How does genetic architecture constrain evolutionary trajectories? To address this question, we inferred the genetic architecture of convergent plumage coloration and its evolutionary history in wheatears.
How does genetic architecture constrain evolutionary trajectories? To address this question, we inferred the genetic architecture of convergent plumage coloration and its evolutionary history in wheatears.
A mosaic of modular variation at a single gene underpins convergent plumage coloration
The reshuffling of genomic variation from multiple origins is an important contributor to phenotypic diversification, yet insights into the evolutionary trajectories of this combinatorial process and ...
www.science.org
October 17, 2025 at 5:50 AM
1/9 New in @science.org www.science.org/doi/10.1126/science.ado8005
How does genetic architecture constrain evolutionary trajectories? To address this question, we inferred the genetic architecture of convergent plumage coloration and its evolutionary history in wheatears.
How does genetic architecture constrain evolutionary trajectories? To address this question, we inferred the genetic architecture of convergent plumage coloration and its evolutionary history in wheatears.
Reposted by MEPGT
Celebrating the first 1000 genomes of Lepidoptera in Europe, sequenced at @sangerinstitute.bsky.social in collaboration with sampling hubs across the UK via the DToL project www.darwintreeoflife.org & across Europe via
@projectpsyche.bsky.social www.projectpsyche.org &
@10klepgenomes.bsky.social
@projectpsyche.bsky.social www.projectpsyche.org &
@10klepgenomes.bsky.social
October 15, 2025 at 9:17 PM
Celebrating the first 1000 genomes of Lepidoptera in Europe, sequenced at @sangerinstitute.bsky.social in collaboration with sampling hubs across the UK via the DToL project www.darwintreeoflife.org & across Europe via
@projectpsyche.bsky.social www.projectpsyche.org &
@10klepgenomes.bsky.social
@projectpsyche.bsky.social www.projectpsyche.org &
@10klepgenomes.bsky.social
Reposted by MEPGT
Extreme female philopatry in Pachypus beetles reveals 14 cryptic species!
🧬 Our study shows ancient speciation (5.3mya) despite limited dispersal, linked to the Messinian salinity crisis. Integrative taxonomy uncovers hidden diversity. #Taxonomy #Genetics url: academic.oup.com/sysbio/artic...
🧬 Our study shows ancient speciation (5.3mya) despite limited dispersal, linked to the Messinian salinity crisis. Integrative taxonomy uncovers hidden diversity. #Taxonomy #Genetics url: academic.oup.com/sysbio/artic...
Cryptic species can be phylogenetically old despite strong sex-biased dispersal
Abstract. The impact of strongly differentiated populations on species delimitation due to limited or sex-biased dispersal remains challenging and under-ex
academic.oup.com
October 15, 2025 at 7:41 AM
Extreme female philopatry in Pachypus beetles reveals 14 cryptic species!
🧬 Our study shows ancient speciation (5.3mya) despite limited dispersal, linked to the Messinian salinity crisis. Integrative taxonomy uncovers hidden diversity. #Taxonomy #Genetics url: academic.oup.com/sysbio/artic...
🧬 Our study shows ancient speciation (5.3mya) despite limited dispersal, linked to the Messinian salinity crisis. Integrative taxonomy uncovers hidden diversity. #Taxonomy #Genetics url: academic.oup.com/sysbio/artic...