Matt Hurles
@mehurles.bsky.social
Director, Wellcome Sanger Institute. Decipherer of developmental disorders. Co-founder Congenica. Dad, husband, cyclist, gardener. Views own.
Reposted by Matt Hurles
An important step towards being able to predict gene expression from DNA sequence - cooperative binding of TFs to DNA characterised at an unprecedented scale
One step closer to unlocking the mystery of the genome: ✅
Our researchers have uncovered more about the complex ‘language’ of the genome, providing interesting insights into gene regulation and human development. 🧬
Read more here ⬇️
bit.ly/3YqDzYK
Our researchers have uncovered more about the complex ‘language’ of the genome, providing interesting insights into gene regulation and human development. 🧬
Read more here ⬇️
bit.ly/3YqDzYK
April 9, 2025 at 4:26 PM
An important step towards being able to predict gene expression from DNA sequence - cooperative binding of TFs to DNA characterised at an unprecedented scale
Reposted by Matt Hurles
One for the #HumanGenetics community! 🧬
@mehurles.bsky.social @hilarycmartin.bsky.social @carlanderson.bsky.social
@mehurles.bsky.social @hilarycmartin.bsky.social @carlanderson.bsky.social
Join leading experts working in #RareDisease research at our #GRD25 conference.
📅 Dates: 9-11 April 2025
💭 Share insights in person
Explore the latest #genomics advances accelerating improvements in clinical care for rare disorders, globally.
⏰Secure your place by 11 March: bit.ly/3BpAe44
📅 Dates: 9-11 April 2025
💭 Share insights in person
Explore the latest #genomics advances accelerating improvements in clinical care for rare disorders, globally.
⏰Secure your place by 11 March: bit.ly/3BpAe44
February 17, 2025 at 2:43 PM
One for the #HumanGenetics community! 🧬
@mehurles.bsky.social @hilarycmartin.bsky.social @carlanderson.bsky.social
@mehurles.bsky.social @hilarycmartin.bsky.social @carlanderson.bsky.social
Reposted by Matt Hurles
Gene editing technology began by people studying salt marshes. Ozempic began by folks studying the venom of Gila Monsters. Support for basic science has empowered us to understand our world. Tethering it to applications health has transformed and saved countless lives.
February 8, 2025 at 1:45 PM
Gene editing technology began by people studying salt marshes. Ozempic began by folks studying the venom of Gila Monsters. Support for basic science has empowered us to understand our world. Tethering it to applications health has transformed and saved countless lives.
Reposted by Matt Hurles
We are happy to share our enhancer scramble story, a strategy to create hundreds of stochastic deletions, inversions, and duplications within mammalian gene regulatory regions and associate these new architectures with gene expression levels 🧵
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
January 15, 2025 at 8:32 PM
We are happy to share our enhancer scramble story, a strategy to create hundreds of stochastic deletions, inversions, and duplications within mammalian gene regulatory regions and associate these new architectures with gene expression levels 🧵
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Matt Hurles
The Sudlow Review of the UK's health data landscape together with 5 corresponding recommendations has been released 👉 www.hdruk.ac.uk/helping-with...
November 12, 2024 at 10:05 AM
The Sudlow Review of the UK's health data landscape together with 5 corresponding recommendations has been released 👉 www.hdruk.ac.uk/helping-with...