Matt Donnelly
@mattdonnelly96.bsky.social
G3 MD/PhD student @UCSDMedSchool in Shadel Lab @salkinstitute | Interested in all things mitochondria, metabolism, and cardiovascular disease
Reposted by Matt Donnelly
congrats @delgoffelab.bsky.social !
Redirecting glucose flux during in vitro expansion generates epigenetically and metabolically superior T cells for cancer immunotherapy: Cell Metabolism www.cell.com/cell-metabol...
Redirecting glucose flux during in vitro expansion generates epigenetically and metabolically superior T cells for cancer immunotherapy: Cell Metabolism www.cell.com/cell-metabol...
Redirecting glucose flux during in vitro expansion generates epigenetically and metabolically superior T cells for cancer immunotherapy
T cell therapies for cancer currently rely on extensive in vitro expansion in hypermetabolic
conditions. Frisch et al. demonstrate that T cells grown in vitro perform extensive
aerobic glycolysis. Rer...
www.cell.com
January 29, 2025 at 7:40 AM
congrats @delgoffelab.bsky.social !
Redirecting glucose flux during in vitro expansion generates epigenetically and metabolically superior T cells for cancer immunotherapy: Cell Metabolism www.cell.com/cell-metabol...
Redirecting glucose flux during in vitro expansion generates epigenetically and metabolically superior T cells for cancer immunotherapy: Cell Metabolism www.cell.com/cell-metabol...
Reposted by Matt Donnelly
New: Sainz, Shadel et al. @salkinstitute.bsky.social investigate mitochondrial respiration-independent signaling induced by acute mtDNA depletion and uncover a role for FAM43A in a CHK2-dependent mitochondrial stress signaling pathway. https://buff.ly/40MBmIW
#mitochondria
#mitochondria
January 27, 2025 at 5:16 PM
New: Sainz, Shadel et al. @salkinstitute.bsky.social investigate mitochondrial respiration-independent signaling induced by acute mtDNA depletion and uncover a role for FAM43A in a CHK2-dependent mitochondrial stress signaling pathway. https://buff.ly/40MBmIW
#mitochondria
#mitochondria
First post and first #fluorescencefriday has to go to a classic combination:
Outer mitochondrial membrane marker TOMM20(💙) and matrix protein HSP60 (❤️) in HEK cells!
#microscopy #cellbiology
Outer mitochondrial membrane marker TOMM20(💙) and matrix protein HSP60 (❤️) in HEK cells!
#microscopy #cellbiology
December 21, 2024 at 12:02 AM
First post and first #fluorescencefriday has to go to a classic combination:
Outer mitochondrial membrane marker TOMM20(💙) and matrix protein HSP60 (❤️) in HEK cells!
#microscopy #cellbiology
Outer mitochondrial membrane marker TOMM20(💙) and matrix protein HSP60 (❤️) in HEK cells!
#microscopy #cellbiology