Reposted
Excited to share the first paper from my lab 🤩 - a great collaboration with Dani Fachinetti lab - we discover a #mechanosensitive nuclear envelope #checkpoint that arrests cells directly post chromosome mis-segregation rdcu.be/d5AC9 👇🧵 #cancer #mechanics #p53 #chromatin
January 8, 2025 at 12:14 PM
Excited to share the first paper from my lab 🤩 - a great collaboration with Dani Fachinetti lab - we discover a #mechanosensitive nuclear envelope #checkpoint that arrests cells directly post chromosome mis-segregation rdcu.be/d5AC9 👇🧵 #cancer #mechanics #p53 #chromatin
Reposted
"[My adviser] told me that instead of focusing on finding a dream job, I should think about what I am good at and what makes me happy at least 80% of the time. This advice surprised me at first, but it ended up being exactly what I needed to hear." scim.ag/3DHtLCc
To choose a career, I needed to do more than ‘follow my dream’
Practical advice helped this international scientist figure out her post-Ph.D. direction
scim.ag
January 8, 2025 at 8:15 PM
"[My adviser] told me that instead of focusing on finding a dream job, I should think about what I am good at and what makes me happy at least 80% of the time. This advice surprised me at first, but it ended up being exactly what I needed to hear." scim.ag/3DHtLCc
Reposted
Senescent cells can promote health and have physiological roles. #Science
"Senescent cells also have essential physiological functions, such as in tumor suppression, development, wound healing, tissue remodeling, regeneration, and vasculature."
www.science.org/doi/10.1126/...
"Senescent cells also have essential physiological functions, such as in tumor suppression, development, wound healing, tissue remodeling, regeneration, and vasculature."
www.science.org/doi/10.1126/...
January 6, 2025 at 9:11 AM
Senescent cells can promote health and have physiological roles. #Science
"Senescent cells also have essential physiological functions, such as in tumor suppression, development, wound healing, tissue remodeling, regeneration, and vasculature."
www.science.org/doi/10.1126/...
"Senescent cells also have essential physiological functions, such as in tumor suppression, development, wound healing, tissue remodeling, regeneration, and vasculature."
www.science.org/doi/10.1126/...
Reposted
Bom texto sobre metabolismo, peso e idade.
O principal: peder quilos em pouco tempo é má ideia pois não mudamos o ponto de ajuste, e nosso organismo trabalha duro para voltar ao último peso.
Não às dietas restritivas e sim às perdas sutis e intervaladas.
theconversation.com/most-adults-...
O principal: peder quilos em pouco tempo é má ideia pois não mudamos o ponto de ajuste, e nosso organismo trabalha duro para voltar ao último peso.
Não às dietas restritivas e sim às perdas sutis e intervaladas.
theconversation.com/most-adults-...
Most adults will gain half a kilo this year – and every year. Here’s how to stop ‘weight creep’
‘Weight creep’ doesn’t have to be inevitable. Here’s what’s behind this sneaky annual occurrence and some practical steps to prevent it.
theconversation.com
January 5, 2025 at 11:42 AM
Bom texto sobre metabolismo, peso e idade.
O principal: peder quilos em pouco tempo é má ideia pois não mudamos o ponto de ajuste, e nosso organismo trabalha duro para voltar ao último peso.
Não às dietas restritivas e sim às perdas sutis e intervaladas.
theconversation.com/most-adults-...
O principal: peder quilos em pouco tempo é má ideia pois não mudamos o ponto de ajuste, e nosso organismo trabalha duro para voltar ao último peso.
Não às dietas restritivas e sim às perdas sutis e intervaladas.
theconversation.com/most-adults-...
Reposted
Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR)
"Tailored exercise prescription sequence for older adults"
Open Access
www.sciencedirect.com/science/arti...
"Tailored exercise prescription sequence for older adults"
Open Access
www.sciencedirect.com/science/arti...
January 5, 2025 at 1:08 PM
Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR)
"Tailored exercise prescription sequence for older adults"
Open Access
www.sciencedirect.com/science/arti...
"Tailored exercise prescription sequence for older adults"
Open Access
www.sciencedirect.com/science/arti...
Reposted
New study on the pathogenic role of hypoxia in #BloodBrainBarrier disruption, with implications for vascular dementia #cerebrovascular academic.oup.com/braincomms/a...
Blood–brain barrier disruption and microglial activation during hypoxia and post-hypoxic recovery in aged mice
Sapkota et al. show that hypoxia triggers vascular breakdown and microglial activation in the brain. While return to normoxia results in vascular repair, m
academic.oup.com
January 4, 2025 at 3:14 PM
New study on the pathogenic role of hypoxia in #BloodBrainBarrier disruption, with implications for vascular dementia #cerebrovascular academic.oup.com/braincomms/a...
Reposted
In news that surprises no scientist in cancer research, alcohol is linked to several cancers.
Alcohol has one of the strongest links to increased cancer risk of any modifiable risk factors.
I wrote about cancer basics here, including modifiable risk factors:
news.immunologic.org/p/cancer-hun...
Alcohol has one of the strongest links to increased cancer risk of any modifiable risk factors.
I wrote about cancer basics here, including modifiable risk factors:
news.immunologic.org/p/cancer-hun...
Cancer: hundreds of complex diseases that are plagued with misinformation
Lack of understanding of cancer underlies harmful pseudoscience that circulates rampantly
news.immunologic.org
January 3, 2025 at 10:23 PM
In news that surprises no scientist in cancer research, alcohol is linked to several cancers.
Alcohol has one of the strongest links to increased cancer risk of any modifiable risk factors.
I wrote about cancer basics here, including modifiable risk factors:
news.immunologic.org/p/cancer-hun...
Alcohol has one of the strongest links to increased cancer risk of any modifiable risk factors.
I wrote about cancer basics here, including modifiable risk factors:
news.immunologic.org/p/cancer-hun...
Reposted
Ten simple rules for developing good reading habits during graduate school and beyond
"Rule 1: Develop the habit of reading on a daily basis"
journals.plos.org/ploscompbiol...
"Rule 1: Develop the habit of reading on a daily basis"
journals.plos.org/ploscompbiol...
January 2, 2025 at 2:49 PM
Ten simple rules for developing good reading habits during graduate school and beyond
"Rule 1: Develop the habit of reading on a daily basis"
journals.plos.org/ploscompbiol...
"Rule 1: Develop the habit of reading on a daily basis"
journals.plos.org/ploscompbiol...
Reposted
🧪O pequeno exercício que é um poderoso estimulante do humor
Lembrar as coisas positivas que aconteceram ao longo do seu dia é uma tarefa que combate a arraigada tendência humana de registrar e relembrar o negativo, não o positivo.
Lembrar as coisas positivas que aconteceram ao longo do seu dia é uma tarefa que combate a arraigada tendência humana de registrar e relembrar o negativo, não o positivo.
O pequeno exercício que é um poderoso estimulante do humor
Lembrar as coisas positivas que aconteceram ao longo do seu dia é uma tarefa que combate a arraigada tendência humana de registrar e relembrar o negativo, não o positivo.
www.correiobraziliense.com.br
January 1, 2025 at 8:41 PM
🧪O pequeno exercício que é um poderoso estimulante do humor
Lembrar as coisas positivas que aconteceram ao longo do seu dia é uma tarefa que combate a arraigada tendência humana de registrar e relembrar o negativo, não o positivo.
Lembrar as coisas positivas que aconteceram ao longo do seu dia é uma tarefa que combate a arraigada tendência humana de registrar e relembrar o negativo, não o positivo.
Reposted
A #ScienceReview from last year highlights the growing recognition of the complex cognitive capacities of #rats and its implications for how they are treated in scientific contexts.
The complex affective and cognitive capacities of rats
For several decades, although studies of rat physiology and behavior have abounded, research on rat emotions has been limited in scope to fear, anxiety, and pain. Converging evidence for the capacity of many species to share others' affective states has...
scim.ag
January 1, 2025 at 3:07 PM
A #ScienceReview from last year highlights the growing recognition of the complex cognitive capacities of #rats and its implications for how they are treated in scientific contexts.
Reposted
Muscle matters: the effects of medically induced weight loss on skeletal muscle
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
December 31, 2024 at 11:06 AM
Muscle matters: the effects of medically induced weight loss on skeletal muscle
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted
Don’t give in to pessimism, says Pope Francis in BBC Thought for the Day
Don’t give in to pessimism, says Pope Francis in BBC Thought for the Day
Hope and kindness ‘touch the very heart of gospel’ and show people how to behave amid war and social injustice
Pope Francis has urged people not to be drawn towards “pessimism and resignation” despite wars and social injustices throughout the world, but…
www.theguardian.com
December 28, 2024 at 9:52 AM
Don’t give in to pessimism, says Pope Francis in BBC Thought for the Day
Reposted
Breathing polluted air increases the risk of osteoporosis. #Science
Open Access
www.science.org/doi/epdf/10....
Open Access
www.science.org/doi/epdf/10....
December 28, 2024 at 2:48 AM
Breathing polluted air increases the risk of osteoporosis. #Science
Open Access
www.science.org/doi/epdf/10....
Open Access
www.science.org/doi/epdf/10....
Reposted
December 26, 2024 at 5:07 PM
Reposted
Cold-induced changes in plasma signaling lipids are associated with a healthier cardiometabolic profile independently of brown adipose tissue
www.cell.com/cell-reports...
www.cell.com/cell-reports...
December 25, 2024 at 10:51 AM
Cold-induced changes in plasma signaling lipids are associated with a healthier cardiometabolic profile independently of brown adipose tissue
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Reposted
Microglia in the aged brain develop a hypoactive molecular phenotype after surgery
Zhuoran Yin et al. 🧪
jneuroinflammation.biomedcentral.com/articles/10....
Zhuoran Yin et al. 🧪
jneuroinflammation.biomedcentral.com/articles/10....
Microglia in the aged brain develop a hypoactive molecular phenotype after surgery - Journal of Neuroinflammation
Background Microglia, the resident immune cells of the brain, play a crucial role in maintaining homeostasis in the central nervous system (CNS). However, they can also contribute to neurodegeneration...
jneuroinflammation.biomedcentral.com
December 25, 2024 at 1:26 PM
Microglia in the aged brain develop a hypoactive molecular phenotype after surgery
Zhuoran Yin et al. 🧪
jneuroinflammation.biomedcentral.com/articles/10....
Zhuoran Yin et al. 🧪
jneuroinflammation.biomedcentral.com/articles/10....
Reposted
To supply a fertility industry worth billions, women in India, Argentina, Greece and Taiwan get paid for their eggs—and sometimes pay dearly
The Global Fertility Trade: A Story of Extraction, Exploitation and Opportunity
Following human eggs as they’re exchanged across open, gray and black markets — reaping rewards for an extremely high price.
www.bloomberg.com
December 22, 2024 at 5:45 PM
To supply a fertility industry worth billions, women in India, Argentina, Greece and Taiwan get paid for their eggs—and sometimes pay dearly
Reposted
This is the face of a shark! I've stained the mineralised tissues to show that their teeth and scales are both made of the same enamel-like material 🦈 🦷 🧪
December 11, 2024 at 10:01 AM
This is the face of a shark! I've stained the mineralised tissues to show that their teeth and scales are both made of the same enamel-like material 🦈 🦷 🧪
Reposted
Watching at 2:30 a.m. Sunday. Do I know how to party, or what?
youtu.be/yQ6VOOd73MA?...
youtu.be/yQ6VOOd73MA?...
Your Brain: Who's in Control? | Full Documentary | NOVA | PBS
YouTube video by NOVA PBS Official
youtu.be
December 8, 2024 at 10:32 AM
Watching at 2:30 a.m. Sunday. Do I know how to party, or what?
youtu.be/yQ6VOOd73MA?...
youtu.be/yQ6VOOd73MA?...
Reposted
Engineered platelets as targeted protein degraders and application to breast cancer models. @naturebiotech.bsky.social
"DePLTs engineered with corresponding POI ligands effectively suppressed cancer recurrence or metastasis."
Read more
www.nature.com/articles/s41...
"DePLTs engineered with corresponding POI ligands effectively suppressed cancer recurrence or metastasis."
Read more
www.nature.com/articles/s41...
December 5, 2024 at 3:23 AM
Engineered platelets as targeted protein degraders and application to breast cancer models. @naturebiotech.bsky.social
"DePLTs engineered with corresponding POI ligands effectively suppressed cancer recurrence or metastasis."
Read more
www.nature.com/articles/s41...
"DePLTs engineered with corresponding POI ligands effectively suppressed cancer recurrence or metastasis."
Read more
www.nature.com/articles/s41...
Reposted
Here's the head of an ant imaged with scanning electron microscopy during my PhD (back in 2018 🥲) 🐜 🧪
December 5, 2024 at 9:18 AM
Here's the head of an ant imaged with scanning electron microscopy during my PhD (back in 2018 🥲) 🐜 🧪
Reposted
🎯Core Metabolic Roadmap
How to get the molecules that are needed, when they’re needed.
Source & High resolution:
Bibel, B., & The bumbling biochemist. (2024). Core Metabolic Roadmap. Zenodo.
zenodo.org/records/1336...
How to get the molecules that are needed, when they’re needed.
Source & High resolution:
Bibel, B., & The bumbling biochemist. (2024). Core Metabolic Roadmap. Zenodo.
zenodo.org/records/1336...
December 4, 2024 at 5:58 AM
🎯Core Metabolic Roadmap
How to get the molecules that are needed, when they’re needed.
Source & High resolution:
Bibel, B., & The bumbling biochemist. (2024). Core Metabolic Roadmap. Zenodo.
zenodo.org/records/1336...
How to get the molecules that are needed, when they’re needed.
Source & High resolution:
Bibel, B., & The bumbling biochemist. (2024). Core Metabolic Roadmap. Zenodo.
zenodo.org/records/1336...
Reposted
Your friends shape your microbiome
"Analysis of nearly 2,000 people living in remote villages in Honduras reveals who’s spreading gut microorganisms to whom." @natureportfolio.bsky.social #scisky #Medsky #microbiome
Open Access
www.nature.com/articles/s41...
"Analysis of nearly 2,000 people living in remote villages in Honduras reveals who’s spreading gut microorganisms to whom." @natureportfolio.bsky.social #scisky #Medsky #microbiome
Open Access
www.nature.com/articles/s41...
December 4, 2024 at 3:22 PM
Your friends shape your microbiome
"Analysis of nearly 2,000 people living in remote villages in Honduras reveals who’s spreading gut microorganisms to whom." @natureportfolio.bsky.social #scisky #Medsky #microbiome
Open Access
www.nature.com/articles/s41...
"Analysis of nearly 2,000 people living in remote villages in Honduras reveals who’s spreading gut microorganisms to whom." @natureportfolio.bsky.social #scisky #Medsky #microbiome
Open Access
www.nature.com/articles/s41...
Reposted
"Authoritative tips for manuscript preparation" #Matter
Edward Sargent shares ten tips on writing successful research articles.
Open Access
www.cell.com/matter/fullt...
Edward Sargent shares ten tips on writing successful research articles.
Open Access
www.cell.com/matter/fullt...
December 3, 2024 at 2:42 PM
"Authoritative tips for manuscript preparation" #Matter
Edward Sargent shares ten tips on writing successful research articles.
Open Access
www.cell.com/matter/fullt...
Edward Sargent shares ten tips on writing successful research articles.
Open Access
www.cell.com/matter/fullt...