Martin Schostak MD, PhD
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martin-schostak.bsky.social
Martin Schostak MD, PhD
@martin-schostak.bsky.social
Professor of Urology, Berlin, Germany. Urologic Cancer Surgeon and urologic oncologist
Head of German Focal Treatment Experts
Head of https://logicuro.com
Reposted by Martin Schostak MD, PhD
Microultrasonography-Guided vs MRI-Guided Biopsy for Prostate Cancer Diagnosis: The OPTIMUM Randomized Clinical Trial

jamanetwork.com/journals/jam...

These findings suggest that microultrasonography could serve as an alternative to MRI for prostate cancer diagnosis.
#ProstateCancer
Microultrasonography-Guided vs MRI-Guided Biopsy for Prostate Cancer Diagnosis
This randomized, noninferiority trial of biopsy-naive men compares the detection of Gleason Grade Group ≥2 prostate cancer using microultrasonography-guided and MRI fusion-guided biopsy.
jamanetwork.com
March 26, 2025 at 4:07 PM
Proud to be one of the investigators: #MicroUS noninferior to MRI fusion for csPCa (46.1% vs 42.6%)! No MRI, slightly better results. 802 pts, 8 countries. Just presented #EAU25 and published in #JAMA. #ProstateCancer #biopsy @axelmerseburger.bsky.social
March 24, 2025 at 11:38 AM
LATP hits harder: +5.7% GG≥2 vs TRUS (p=0.031)! Fewer infections, slightly more pain & embarrassment. No abx needed. Costlier, slower—but sharper. #TRANSLATEtrial #ProstateCancer #LATP #TRUS #EAU25 #LancetOncology @axelmerseburger.bsky.social
March 24, 2025 at 11:36 AM
The very first post-ASCO GU meeting this year ! @yukselurun.bsky.social
February 16, 2025 at 10:41 PM
Reposted by Martin Schostak MD, PhD
@erplimackmd.bsky.social with killer discussion setting the scene for the #NIAGARA “sandwich” & #Checkmate274, both practice changing for our pts w #bladdercancer. @ascocancer.bsky.social #GU25
February 14, 2025 at 5:07 PM
🚀 Excited for #ASCOGU25! Looking forward to groundbreaking insights and game-changers once again! 🔬 Can't wait to see what’s ahead. 🎯 Stay tuned! #UroOncology #GameChanger
@axelmerseburger.bsky.social
February 8, 2025 at 2:38 PM
🔥 #TestisCancer highlight from #ASCOGU!

📌 Abstract 618 – Final results of the #COTRIMS trial: Retroperitoneal lymphadenectomy in metastatic #Seminoma.

Important data for #GermCellTumors! What’s your take?
February 8, 2025 at 9:30 AM
🚀 Key #UrothelialCancer abstracts from #ASCOGU!
📌 Abstract 661 – #Durvalumab (#MEDI4736) + neoadjuvant chemo (#Gemcitabine + #Cisplatin / #Carboplatin) in high-risk upper tract urothelial carcinoma.
📌 Abstract 667 – #Durvalumab + intravesical #Gemcitabine & #Docetaxel in #BCG-unresponsive NMIBC.
February 8, 2025 at 9:29 AM
🔥 Exciting #ProstateCancer Abstracts from #ASCOGU:
📌 LBA18 – Final overall survival results of the phase 3 #TALAPRO2 trial.
📌 Abstract 21 – Transdermal #Estradiol (#tE2) patches + #ARPIs in metastatic (#M1) prostate cancer.
📌 Abstract 22 – #Metastases-directed therapy in oligometastatic #CRPC.
February 8, 2025 at 9:28 AM
Reposted by Martin Schostak MD, PhD
Patients receiving a personalized cancer vaccine #PCV for #renalcellcarcinoma remained cancer-free after 40 months, according to a phase 1 study led by Dr. David Braun and @danafarber.bsky.social colleagues published today in
#Nature.
yalecancercenter.org/news-article...
Personalized therapeutic vaccine ‘steers’ the immune system to fight kidney cancer
Vaccines are on the cutting edge of cancer therapy research as a possible treatment option for the future. The trial led by Yale Cancer Center (YCC) principal
yalecancercenter.org
February 5, 2025 at 7:05 PM
Reposted by Martin Schostak MD, PhD
Our paper in @nature.com is finally published: a prospective trial of a personalized Neoantigen Vaccine in Kidney Cancer

www.nature.com/articles/s41...

This is teamwork with @danafarber.bsky.social @yalecancer.bsky.social @harvardmed.bsky.social + Wu lab

www.nature.com/articles/s41...
February 5, 2025 at 7:18 PM
Zigtausende bei #Anstand-gegen-Rechts im #Tiergarten. So geht #Demokratie
February 2, 2025 at 3:58 PM
February 2, 2025 at 2:44 PM
Reposted by Martin Schostak MD, PhD
🔵1 in 3 men experience PSA persistence or relapse within 10 years post-radical prostatectomy.
🔵Early relapse (<2 years) = higher PCa death risk (8.5%) vs. late relapse (>5 years, 1.4%).
🔵Life expectancy and relapse timing guide treatment. #ProstateCancer #Oncology
@oncoalert.bsky.social
January 20, 2025 at 7:13 PM
Reposted by Martin Schostak MD, PhD
🧬💊2024 FDA approvals highlight cancer as a priority: 15 (30%) novel drugs, including the 11th PD1/PDL1 blocker.
🎯 Our mission is clear: ensure the right treatment is available and accessible to every patient. Equity in care is non-negotiable.
@oncoalert.bsky.social @oncbrothers.bsky.social
January 4, 2025 at 3:54 PM
Reposted by Martin Schostak MD, PhD
THE best presentation of study figures ever! 😆

"We presented scaled versions of this puzzle to both people and ants (Fig. 1 A and B)."

per Proceedings of the National Academy of Sciences @pnas.org

www.pnas.org/doi/10.1073/...
December 27, 2024 at 7:59 PM
Reposted by Martin Schostak MD, PhD
“FDA Approves Subcutaneous Nivolumab in Advanced or Metastatic Solid Tumors”.
Great news for patients, more convenient treatments, and less time- and resource-consuming schedules. www.onclive.com/view/fda-app...
FDA Approves Subcutaneous Nivolumab in Advanced or Metastatic Solid Tumors
The FDA has approved nivolumab and hyaluronidase-nvhy (Opdivo Qvantig) for subcutaneous injection across approved adult solid tumor nivolumab (Opdivo) indications.
www.onclive.com
December 27, 2024 at 8:29 PM
Reposted by Martin Schostak MD, PhD
#Nectin4 in GU vs other malignancies
✅ Nectin4 is more prevalent in GU cancers than others
✅ still more data needed on the prognostic and predictive value
👉 Interested in more data on how prior treatment impacts Nectin4 + how this could impact treatment sequence @oncodaily.bsky.social #BladderCancer
December 8, 2024 at 4:47 AM
Reposted by Martin Schostak MD, PhD
Adjuvant nivolumab continues to show significant benefits in MIUC. At 36.1 months, DFS & OS improved in ITT (DFS HR 0.71, OS HR 0.76) and PD-L1 ≥1% (DFS HR 0.52, OS HR 0.56). No new safety signals. #oncology #cancer @oncoalert.bsky.social

doi.org/10.1200/JCO....
December 24, 2024 at 5:57 AM
Wieso ist der #X-Account des #Magdeburg-Attentäters mit fast 50.000 Followern nach über drei Tagen noch immer online? Wenn die #Plattform #X schon nicht agiert, vielleicht sogar, weil ihr Chef eine solche „Meinungsfreiheit“ unterstützt, warum tut das BKA oder das Innenministerium denn auch nichts?
December 23, 2024 at 10:38 PM
Reposted by Martin Schostak MD, PhD
Initial active surveillance and watchful waiting significantly increased for intermediate–risk prostate cancer between 2010 and 2020.

https://ja.ma/4042h
PZ
December 22, 2024 at 8:00 PM
Reposted by Martin Schostak MD, PhD
I am not only leaving the University of #Magdeburg but also #X
You can now find me here and at logicuro.com
December 23, 2024 at 4:42 PM