Mark McCarthy
@markmccarthy985.bsky.social
Bluesky newbie. Twitter exile. Previously Professor of Diabetes in Oxford, now heading human genetics at Genentech. Living the California dream. Views my own. #YNWA
Reposted by Mark McCarthy
Spending tonight with everyone’s favorite Glaswegians, Mogwai
April 29, 2025 at 4:26 AM
Spending tonight with everyone’s favorite Glaswegians, Mogwai
Reposted by Mark McCarthy
MOGWAI - San Francisco, April 28, 2025
Because sometimes you just want to atomize yourself in a wave of guitar feedback
Because sometimes you just want to atomize yourself in a wave of guitar feedback
April 29, 2025 at 7:08 AM
MOGWAI - San Francisco, April 28, 2025
Because sometimes you just want to atomize yourself in a wave of guitar feedback
Because sometimes you just want to atomize yourself in a wave of guitar feedback
It’s never a bad day when Mogwai shows up in town. First saw them in 1999. Love them more than ever…..
April 29, 2025 at 5:37 AM
It’s never a bad day when Mogwai shows up in town. First saw them in 1999. Love them more than ever…..
Reposted by Mark McCarthy
1/n Some time ago my colleague, excellent cook, and friend Ivan told me: "Cacio e pepe is the recipe that I screw up more often. Let's make a project studying systematically the physics of that sauce".
Prepare to get cheesy, I'm glad to share the Cacio e paper preprint:
arxiv.org/abs/2501.00536
Prepare to get cheesy, I'm glad to share the Cacio e paper preprint:
arxiv.org/abs/2501.00536
January 4, 2025 at 9:34 AM
1/n Some time ago my colleague, excellent cook, and friend Ivan told me: "Cacio e pepe is the recipe that I screw up more often. Let's make a project studying systematically the physics of that sauce".
Prepare to get cheesy, I'm glad to share the Cacio e paper preprint:
arxiv.org/abs/2501.00536
Prepare to get cheesy, I'm glad to share the Cacio e paper preprint:
arxiv.org/abs/2501.00536
Reposted by Mark McCarthy
Long awaited peer review finally completed!! Our paper comparing quantitative metabolomics disease risk prediction with PGS is accepted in Nature Comms!! 🥳🥳
@nightingalehealth.com #riskprediction #metabolomics #nmr #genomics #polygenicscore
www.nature.com/articles/s41...
@nightingalehealth.com #riskprediction #metabolomics #nmr #genomics #polygenicscore
www.nature.com/articles/s41...
Metabolomic and genomic prediction of common diseases in 700,217 participants in three national biobanks - Nature Communications
Identifying individuals at high risk for chronic diseases can improve prevention. Here, the authors show that blood metabolomics scores effectively stratify disease risk and compare favorably to genet...
www.nature.com
December 4, 2024 at 11:46 AM
Long awaited peer review finally completed!! Our paper comparing quantitative metabolomics disease risk prediction with PGS is accepted in Nature Comms!! 🥳🥳
@nightingalehealth.com #riskprediction #metabolomics #nmr #genomics #polygenicscore
www.nature.com/articles/s41...
@nightingalehealth.com #riskprediction #metabolomics #nmr #genomics #polygenicscore
www.nature.com/articles/s41...
Reposted by Mark McCarthy
A wonderful paper from @tonyzador.bsky.social and colleagues: Encoding innate ability through a genomic bottleneck www.pnas.org/doi/10.1073/...
Encoding innate ability through a genomic bottleneck | PNAS
Animals are born with extensive innate behavioral capabilities, which arise from neural
circuits encoded in the genome. However, the information ca...
www.pnas.org
November 28, 2024 at 9:57 AM
A wonderful paper from @tonyzador.bsky.social and colleagues: Encoding innate ability through a genomic bottleneck www.pnas.org/doi/10.1073/...
Reposted by Mark McCarthy
Inspiring talk by @christian_happi from @acegid on scaling up genomics infrastructure on the African continent for combatting infectious diseases, from malaria to COVID @QMULBartsTheLon #WHD21
November 22, 2024 at 10:25 AM
Inspiring talk by @christian_happi from @acegid on scaling up genomics infrastructure on the African continent for combatting infectious diseases, from malaria to COVID @QMULBartsTheLon #WHD21
Reposted by Mark McCarthy
Check out our new work led by @ashton_omdahl discussing matrix factorization across GWAS, accounting for sample overlap. Factors with varying polygenicity, enrichment for cell type / developmental stage... Ashton is speaking at #biodata24 today! www.biorxiv.org/content/10.1...
Sparse matrix factorization of GWAS summary statistics robust to sample sharing improves detection and interpretation of factors with diverse genetic architectures
Complex trait-associated genetic variation is highly pleiotropic. This extensive pleiotropy implies that multi-phenotype analyses are informative for characterizing genetic variation, as they facilita...
www.biorxiv.org
November 14, 2024 at 4:46 PM
Check out our new work led by @ashton_omdahl discussing matrix factorization across GWAS, accounting for sample overlap. Factors with varying polygenicity, enrichment for cell type / developmental stage... Ashton is speaking at #biodata24 today! www.biorxiv.org/content/10.1...
Reposted by Mark McCarthy
Others have noted it but I will too: The big reason Bluesky is so hot right now is that the people who add value to social media - the frequent posters in specific fields - are here now, talking to each other and creating the "spectator value" that draws users and attention.
Twitter’s heir apparent isn’t X or Threads — it’s Bluesky
The blue bird is dead. Long live the blue sky.
www.theverge.com
November 23, 2024 at 6:30 PM
Others have noted it but I will too: The big reason Bluesky is so hot right now is that the people who add value to social media - the frequent posters in specific fields - are here now, talking to each other and creating the "spectator value" that draws users and attention.
It’s fantastic to find so many friends already here. As others have noted, this feels like the early days of science twitter (RIP).
November 18, 2024 at 5:00 AM
It’s fantastic to find so many friends already here. As others have noted, this feels like the early days of science twitter (RIP).