Manuel González Fuente
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manuelgonzalezfuen.bsky.social
Manuel González Fuente
@manuelgonzalezfuen.bsky.social
Postdoctoral researcherer at #TheUstunLab in @ruhr-uni-bochum.de working on P-bodies and bacterial pathogens.
🏳️‍🌈 he/him
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It is with great pleasure that I inaugurate my Bluesky account sharing our last @biorxiv-plants.bsky.social at @theustunlab.bsky.social, about pathogen-mediated modulation of host P-bodies and translation. 🆕 🎉

www.biorxiv.org/content/10.1...

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Reposted by Manuel González Fuente
We recently celebrated the 7th anniversary of @theustunlab.bsky.social with a barbecue! Our journey began in Tübingen in September 2018 and has continued in Bochum since 2022. Excited to see what the coming years will bring!
September 20, 2025 at 11:49 AM
Reposted by Manuel González Fuente
Incredibly happy and proud of our Chaonan Shi (chaonan123.bsky.social ), who successfully defended her doctoral thesis yesterday at the @zmbp-tuebingen.bsky.social ! (And what a brilliant defence it was!) 🥳🥳🥳 Congratulations, Dr Shi!!! 🍾🥂🍋‍🟩🌶️ We are so lucky to have you in our team ❤️
October 3, 2025 at 9:34 AM
Reposted by Manuel González Fuente
Very excited to share that our paper "A RALF-brassinosteorid signaling circuit regulates Arabidopsis hypocotyl cell shape" is now published in @currentbiology.bsky.social !

Enjoy reading it!!

www.sciencedirect.com/science/arti...
October 1, 2025 at 2:49 PM
Reposted by Manuel González Fuente
7 years ago,I sat outside @zmbp-tuebingen.bsky.social,gathering the courage to begin a new chapter as a group leader. Now in Bochum, I still need that courage to face challenges—both inside & outside the lab—but after all I’m grateful that I still find joy in what I do. #happybirthday #theustunlab
September 3, 2025 at 6:12 AM
Reposted by Manuel González Fuente
🔥 Fires in Portugal and Spain have sent huge plumes of smoke over the Bay of Biscay this morning. White is clouds, light brown is smoke:
August 15, 2025 at 8:53 AM
Reposted by Manuel González Fuente
If you’re enjoying some calm while others are on holiday, here’s a #NEW #preprint to dive into — led by the brilliant @vbcscitraining.bsky.social student A. Abdrakhmanov:
👇 A quick thread + link:
www.biorxiv.org/content/10.1...
Ancestral P-body proteins rewired for autophagic recycling in the early land plant Marchantia polymorpha
Processing bodies (P-bodies) are conserved ribonucleoprotein (RNP) granules central to RNA metabolism across eukaryotes. Although the mechanisms underlying their assembly are well understood, the path...
www.biorxiv.org
August 11, 2025 at 5:44 AM
Reposted by Manuel González Fuente
We (@manuelgonzalezfuen.bsky.social @margotraffeiner.bsky.social @shanshuo.bsky.social) had a fantastic #2025ISMPMI in Cologne with lots of amazing science and great networking meeting old friends and new ones. Hope to see you all next time in Jeju/South Korea #2027ISMPMI
July 18, 2025 at 8:02 AM
Reposted by Manuel González Fuente
It is depressing to be at an international conference and have everyone be like “what is going on over there”. 🫠 Not exactly making America great.
July 15, 2025 at 7:32 AM
Reposted by Manuel González Fuente
Next in the concurrent session “spatial and temporal session” is @type3lab.bsky.social who will talk about their amazing findings on distinct pseudomonas subpopulations that cooperate to colonize plants #2025ISMPMI
July 17, 2025 at 2:04 PM
Reposted by Manuel González Fuente
If you wanna dive into the world of #proteostasis and its role in plant immunity, visit @margotraffeiner.bsky.social poster (P-405) today. She discovered a novel proteotoxicity regulator (a protease with ubiquitin binding capacities) that plays a role in biotic and abiotic stresses! #2025ISMPMI
July 16, 2025 at 9:34 AM
Reposted by Manuel González Fuente
Happy to meet you at poster no. P-405 and to talk about my project at #2025ISMPMI this afternoon! 🌿
If you wanna dive into the world of #proteostasis and its role in plant immunity, visit @margotraffeiner.bsky.social poster (P-405) today. She discovered a novel proteotoxicity regulator (a protease with ubiquitin binding capacities) that plays a role in biotic and abiotic stresses! #2025ISMPMI
July 16, 2025 at 9:53 AM
Reposted by Manuel González Fuente
Last day of #2025ISMPMI, last poster session: dont miss @shanshuo.bsky.social fantastic poster about how we used a combination of scRNAseq and cell-type specific approaches to reveal the role of autophagy in stomatal & mesophyll immunity during Pseudomonas infection - more info ➡️ P-432 #proteostasis
July 17, 2025 at 7:20 AM
Reposted by Manuel González Fuente
Hannah @mcmicrobes.bsky.social will start her own lab in 2026 (congrats a lot 🥳)- watch out for some job postings in the future - she will continue to work on heat stress and the effect on leaf-microbioata! #2025ISMPMI
July 17, 2025 at 8:51 AM
Reposted by Manuel González Fuente
Sheng Yang leaves the stage for @mcmicrobes.bsky.social who continues to talk about her exciting results on how abiotic stress impacts the leaf-microbiome #2025ISMPMI
July 17, 2025 at 8:38 AM
Reposted by Manuel González Fuente
We start the last day of #2025ISMPMI with Renier van der Hoorn who will present his pioneering work on how pathogens manipulate apoplastic defence
July 17, 2025 at 6:17 AM
Reposted by Manuel González Fuente
#2025ISMPMI Manuel Gonzalez Fuente from the Üstün lab shows how pathogens like Pseudomonas target p bodies with effectors HopM1 and HopN1. ER stress induction by HopM1 counteracts p bodies.
July 15, 2025 at 10:34 AM
Reposted by Manuel González Fuente
Enjoying the free afternoon in Cologne at #2025ISMPMI with @manuelgonzalezfuen.bsky.social @margotraffeiner.bsky.social and Christa 🥂
July 15, 2025 at 4:03 PM
Reposted by Manuel González Fuente
@manuelgonzalezfuen.bsky.social explains that eukaryote P bodies contain translationally inactive RNAs.

Do pathogens induce the formation of these? Yes!

How? Effectors!… that repress ER stress response.

Why? Make plants susceptible by reducing translation of immunity genes.
#2025ISMPMI
July 15, 2025 at 10:34 AM
Reposted by Manuel González Fuente
Now @manuelgonzalezfuen.bsky.social is on stage presenting his exciting project on p-bodies, and how bacteria utilize them to attenuate host translation #proteostasis #2025ISMPMI
July 15, 2025 at 10:26 AM
If you want to hear about our latest work at @suaybuestuen.bsky.social's lab on pathogen manipulation of host translation and P-bodies at #2025ISMPMI, pass by my presentation today at 12:20 in the concurrent session "Effector interference mechanism" (Room M+N).
July 15, 2025 at 6:22 AM
Reposted by Manuel González Fuente
Great to see @geminiteamlab.bsky.social and @bactodeath.bsky.social presenting a lot of unpublished data, new concepts and approaches in plant-microbe interactions! This should be the spirit at this meeting! Very cool plenary session at #2025ISMPMI
July 14, 2025 at 7:58 AM
Reposted by Manuel González Fuente
@manuelgonzalezfuen.bsky.social will talk about how bacteria exploit P-bodies to attenuate host translation

@margotraffeiner.bsky.social presents a novel proteotoxicity regulator and its role in plant immunty

@shanshuo.bsky.social will emphasize the role of autophagy in stomatal immunity
July 13, 2025 at 3:49 PM
Reposted by Manuel González Fuente
If you’re interested in the role of #proteostasis in plant immunity and how pathogens manipulate it visit our contributions at #2025ISMPMI

@manuelgonzalezfuen.bsky.social will talk on Tuesday in the effector interference session

@shanshuo.bsky.social (P-432)

@margotraffeiner.bsky.social (P-405)
July 13, 2025 at 3:44 PM
Reposted by Manuel González Fuente
We made it to cologne (shortest trip to an MPMI ever 😆) looking forward to some great science! #2025ISMPMI #theustunlab
July 13, 2025 at 12:39 PM
Reposted by Manuel González Fuente
Another amazing conference ended - was great to attend two amazing sessions on #proteostasis and #condensates - with @manuelgonzalezfuen.bsky.social having a double feature and winning the Yound Scientist Award in the cell section of @sebiology.bsky.social next stop: IS- MPMI in Cologne! #2025ISMPMI
July 11, 2025 at 11:06 AM