Fahri Küçükali
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maegsul.bsky.social
Fahri Küçükali
@maegsul.bsky.social
180 followers 290 following 5 posts
Postdoctoral researcher at @sleegerslab.bsky.social - VIB CMN working on complex genetics of Alzheimer's. | GWAS, molecular QTLs, TWAS, splicing, long reads, rare variants.
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maegsul.bsky.social
Fahri Küçükali @maegsul.bsky.social · Feb 13
Exciting news! Our paper on GWAS gene prioritization for Creutzfeldt-Jakob Disease is now published in Brain! 🧠🧬 @brain1878.bsky.social

We leverage eQTL and pQTL catalogues to identify prioritized risk genes with potential roles in prion disease.

Check it out here: academic.oup.com/brain/advanc...
Multiomic analyses direct hypotheses for Creutzfeldt-Jakob disease risk genes
Küçükali & Hill et al. integrate GWAS data with transcriptome and proteome-wide association studies to better understand risk factors for sporadic Creu
academic.oup.com
Reposted by Fahri Küçükali
sleegerslab.bsky.social
Last Friday, we shared our research with 1st year Master's students at @uantwerpen.be during the Research Day! We loved their genuine interest and look forward to welcoming several of them to our lab next year.

Great to see Ph.D. students Kato and Ella share their love for science! 🧪
October 28, 2025 at 9:31 AM
Reposted by Fahri Küçükali
medrxivpreprint.bsky.social
Consensus meta-analysis of genome-wide association studies for Alzheimer's disease and related dementia https://www.medrxiv.org/content/10.1101/2025.10.20.25338060v1
October 23, 2025 at 7:26 PM
Reposted by Fahri Küçükali
cmn-vib.bsky.social
The European Alzheimer & Dementia Biobank (EADB) unites cohorts across 18 countries to decode the genetics of Alzheimer’s disease. https://eadb.eu/
At CMN, the @sleegerslab.bsky.social plays a leading role, with postdoc Fahri Küçükali as our in-house EADB specialist.

#CMNcohorts #CMNconsortia
October 9, 2025 at 11:47 AM
Reposted by Fahri Küçükali
verwilt.bsky.social
1 year of 1000 Healthy Elderly Study! As we are closing in on 200 re-inclusions, we took some time to celebrate this amazing milestone. Find more about our study here: bit.ly/4gV9TLk
October 7, 2025 at 11:38 AM
Reposted by Fahri Küçükali
sleegerslab.bsky.social
One year in, nearly 200 re-inclusions and a clearer picture of healthy brain aging!

The 1000 Healthy Elderly Study has become a real engine for discovery.

Thanks to all of our volunteers and a special shout-out to Sofie Van de kerckhoven for the excellence at intake and sampling! bit.ly/4gV9TLk
October 7, 2025 at 11:36 AM
Reposted by Fahri Küçükali
sleegerslab.bsky.social
🚨 #PhD opportunity! Sleegers & Rademakers Labs are looking for a PhD candidate to develop biomarkers for neurological disorders by integrating genomics & transcriptomics data🧠🔬

@cmn-vib.bsky.social 📍 Antwerp, Belgium | 💡 Genetics • Bioinformatics • Neuroscience

Apply 👉 jobs.vib.be/j/124544/joi...
Joint PhD position on developing genetic risk scores as biomarkers for neurological disorders - VIB
The Rademakers team and the Sleegers team at the VIB-UAntwerp Center for Molecular Neurology, Belgium a
jobs.vib.be
October 2, 2025 at 11:57 AM
maegsul.bsky.social
Join us for this great collaborative PhD project! 😊
sleegerslab.bsky.social Sleegers Lab @sleegerslab.bsky.social · Oct 2
🚨 #PhD opportunity! Sleegers & Rademakers Labs are looking for a PhD candidate to develop biomarkers for neurological disorders by integrating genomics & transcriptomics data🧠🔬

@cmn-vib.bsky.social 📍 Antwerp, Belgium | 💡 Genetics • Bioinformatics • Neuroscience

Apply 👉 jobs.vib.be/j/124544/joi...
Joint PhD position on developing genetic risk scores as biomarkers for neurological disorders - VIB
The Rademakers team and the Sleegers team at the VIB-UAntwerp Center for Molecular Neurology, Belgium a
jobs.vib.be
October 2, 2025 at 12:05 PM
Reposted by Fahri Küçükali
cmn-vib.bsky.social
Next up in our #CMNcohorts #CMNconsortia series, we spotlight a collaboration between the @sleegerslab.bsky.social and Dietmar Thal at KU Leuven: a post-mortem brain cohort, now paired with genetic characterization, and transcriptomic profiling underway.
September 25, 2025 at 3:31 PM
Reposted by Fahri Küçükali
verwilt.bsky.social
Over the moon to be selected for the Flemish #PhDCup 2025 for my research at @ugent-fge.bsky.social at the OncoRNALab with @jvdesomp.bsky.social and Pieter Mestdagh! @fwovlaanderen.bsky.social
September 10, 2025 at 7:35 AM
Reposted by Fahri Küçükali
sleegerslab.bsky.social
Our postdoc @verwilt.bsky.social is selected for the @scimingo.bsky.social PhD Cup for his research during his PhD! 💥 Let's see how his findings can impact Alzheimer's Disease 🧠🧬🩸

@fwovlaanderen.bsky.social @ugent-fge.bsky.social @cmn-vib.bsky.social @viblifesciences.bsky.social @uantwerpen.be
verwilt.bsky.social Jasper Verwilt @verwilt.bsky.social · Sep 10
Over the moon to be selected for the Flemish #PhDCup 2025 for my research at @ugent-fge.bsky.social at the OncoRNALab with @jvdesomp.bsky.social and Pieter Mestdagh! @fwovlaanderen.bsky.social
scimingo.bsky.social SciMingo @scimingo.bsky.social · Sep 10
🌪️ Storm aan talent op komst: ontdek de selectie van de Vlaamse #PhDCup 2025 🏆

Lees meer en ontdek alle kandidaten 👉 www.phdcup.be/nieuws/storm...

@uantwerpen.be @kuleuvenuniversity.bsky.social #uhasselt #ugent #vub @fwovlaanderen.bsky.social
September 10, 2025 at 8:08 AM
Reposted by Fahri Küçükali
cmn-vib.bsky.social
Big congrats to @verwilt.bsky.social‬ from the @sleegerslab.bsky.social‬ on his FWO fellowship! He’ll be mapping RNA and DNA in blood, CSF, even tear fluid, to develop non-invasive biomarkers for Alzheimer’s using long-read sequencing. https://tinyurl.com/ym6c8csr
June 30, 2025 at 10:00 AM
Reposted by Fahri Küçükali
gwascatalog.bsky.social
🚨Interested in which genes are the true effectors behind the scenes of the #gwas results? 🚨
This new publication in Nature Genetics, a collaboration between @broadinstitute.org @ebi.embl.org @opentargets.org focuses on approaches to predicted effector gene reporting tinyurl.com/98yxy4hf (1/3) 👇
Realizing the promise of genome-wide association studies for effector gene prediction - Nature Genetics
This Perspective argues that predicting effector genes for complex diseases is a key outcome of genetic association studies where standards are urgently needed to maximize utility, improve interoperab...
tinyurl.com
June 11, 2025 at 9:01 AM
maegsul.bsky.social
Hi #eshg2025!

I’ll be giving the final presentation today on our recent work mapping Alzheimer's disease genetic risk to brain cell-type-specific transcript alterations 🧬🧠

Looking forward to it—see you there! 😄
sleegerslab.bsky.social Sleegers Lab @sleegerslab.bsky.social · May 24
Ciao Milano! We are happy and excited to be here for #eshg2025 @eshg.bsky.social

Come find us during the oral and poster presentations by our team members Fahri Küçükali (@maegsul.bsky.social) & Celeste Laureyssen (@celestelaureyssen.bsky.social) today and tomorrow 🧬 🧠
May 24, 2025 at 9:22 AM
Reposted by Fahri Küçükali
sleegerslab.bsky.social
Ciao Milano! We are happy and excited to be here for #eshg2025 @eshg.bsky.social

Come find us during the oral and poster presentations by our team members Fahri Küçükali (@maegsul.bsky.social) & Celeste Laureyssen (@celestelaureyssen.bsky.social) today and tomorrow 🧬 🧠
May 24, 2025 at 9:18 AM
Reposted by Fahri Küçükali
sleegerslab.bsky.social
Look at us! 🤩 We presented the excuting research going on in our lab at the @uantwerpen.be NeuroDay 2025. So great to with fellow neuroscientist! 🧠
May 22, 2025 at 11:40 AM
Reposted by Fahri Küçükali
sleegerslab.bsky.social
A new chapter in our lab has begun! Our postdoc @verwilt.bsky.social has received an FWO Junior Fellowship to look for non-invasive extracellular biomarkers for Alzheimer’s disease. Stay tuned for some cool research! @fwovlaanderen.bsky.social
verwilt.bsky.social Jasper Verwilt @verwilt.bsky.social · May 22
YOU MUST BE KIDDING ME! 🥳 Extremely happy to be selected as a Junior FWO Postdoctoral fellowship! Stay tuned for novel extracellular biomarkers for Alzheimer’s disease! Can’t wait to jump in these three years! 🧠🩸🧬 #fwo #RNA #cfDNA #alzheimers @fwovlaanderen.bsky.social @sleegerslab.bsky.social
Fwo
There were 1038 applications for the junior fellowships and 439 for the senior fellowships. As a result, the success rate this year fell to 16.1% (-1.3%) for junior postdocs and 25.9% (-7.8%) for senior postdocs.
www.fwo.be
May 22, 2025 at 8:57 AM
Reposted by Fahri Küçükali
verwilt.bsky.social
YOU MUST BE KIDDING ME! 🥳 Extremely happy to be selected as a Junior FWO Postdoctoral fellowship! Stay tuned for novel extracellular biomarkers for Alzheimer’s disease! Can’t wait to jump in these three years! 🧠🩸🧬 #fwo #RNA #cfDNA #alzheimers @fwovlaanderen.bsky.social @sleegerslab.bsky.social
Fwo
There were 1038 applications for the junior fellowships and 439 for the senior fellowships. As a result, the success rate this year fell to 16.1% (-1.3%) for junior postdocs and 25.9% (-7.8%) for senior postdocs.
www.fwo.be
May 22, 2025 at 8:04 AM
maegsul.bsky.social
Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing

www.nature.com/articles/s41...
Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing - Nature Communications
Here the authors identify TNIP1 as a risk factor for a fatal neurodegenerative disorder and discover specific genetic loci associated with the three main subtypes of this disorder. The findings highli...
www.nature.com
April 30, 2025 at 12:39 PM
Reposted by Fahri Küçükali
sleegerslab.bsky.social
Our lab’s recent hackathon ☕🧠💻 was a success: three packed days, one awesome crew, endless ideas. We built fresh neurogenomics tools and leveled-up team vibes 🚀🧬
April 22, 2025 at 4:39 PM
Reposted by Fahri Küçükali
sleegerslab.bsky.social
🚨 PhD Position Alert! 🚨
We're excited to announce a collaborative PhD opportunity with @uantwerpen.be LEMP, investigating the role of mucin splicing in colorectal cancer. If you're passionate about RNA biology, omics, and translational research, this could be the perfect fit!
April 3, 2025 at 3:02 PM
Reposted by Fahri Küçükali
jordanovalab.bsky.social
Rare, but not alone. Today, we light up for #RareDiseaseDay. We recognize the strength of those living with rare diseases and the science that seeks to understand, diagnose, and treat them. #PatientsFirst 🧬 💙
February 28, 2025 at 3:33 PM
maegsul.bsky.social
Exciting news! Our paper on GWAS gene prioritization for Creutzfeldt-Jakob Disease is now published in Brain! 🧠🧬 @brain1878.bsky.social

We leverage eQTL and pQTL catalogues to identify prioritized risk genes with potential roles in prion disease.

Check it out here: academic.oup.com/brain/advanc...
Multiomic analyses direct hypotheses for Creutzfeldt-Jakob disease risk genes
Küçükali & Hill et al. integrate GWAS data with transcriptome and proteome-wide association studies to better understand risk factors for sporadic Creu
academic.oup.com
February 13, 2025 at 1:23 PM
Reposted by Fahri Küçükali
smead2.bsky.social
New paper on risk genes for sporadic CJD academic.oup.com/brain/advanc...
Multiomic analyses direct hypotheses for Creutzfeldt-Jakob disease risk genes
Küçükali & Hill et al. integrate GWAS data with transcriptome and proteome-wide association studies to better understand risk factors for sporadic Creu
academic.oup.com
February 1, 2025 at 5:57 PM
Reposted by Fahri Küçükali
sleegerslab.bsky.social
Very happy to see our review on Alzheimer's disease rare genetic variants published in @natrevneurol.bsky.social! 🧠🧬

Huge congrats to our PhD student @laradedeyn.bsky.social 🎉👏✨

www.nature.com/articles/s41...
February 5, 2025 at 4:07 PM
Reposted by Fahri Küçükali
natrevneurol.nature.com
New online! The impact of rare genetic variants on Alzheimer disease https://bit.ly/4hntQtT
February 4, 2025 at 10:18 PM