mac64.bsky.social
@mac64.bsky.social
Reposted by mac64.bsky.social
NEW: An inside look at how RFK Jr. has walled himself off from government scientists and installed old allies in key positions to advance the vaccine agenda that has animated him for 20 years. "Vaccines must be a culprit," he told me.
w/ @by-cjewett.bsky.social
www.nytimes.com/2025/12/04/u...
w/ @by-cjewett.bsky.social
www.nytimes.com/2025/12/04/u...
Inside Kennedy’s Methodical Quest to Shake Up America’s Vaccine System
www.nytimes.com
December 4, 2025 at 1:32 PM
NEW: An inside look at how RFK Jr. has walled himself off from government scientists and installed old allies in key positions to advance the vaccine agenda that has animated him for 20 years. "Vaccines must be a culprit," he told me.
w/ @by-cjewett.bsky.social
www.nytimes.com/2025/12/04/u...
w/ @by-cjewett.bsky.social
www.nytimes.com/2025/12/04/u...
Reposted by mac64.bsky.social
This does not consider the T cell response or memory B cell response and overstates the number of people at risk for HBV infection. We have data showing that even after 30 years, no boosting is required after the primary series. She also greatly undermines her point in this slide...
December 4, 2025 at 2:29 PM
This does not consider the T cell response or memory B cell response and overstates the number of people at risk for HBV infection. We have data showing that even after 30 years, no boosting is required after the primary series. She also greatly undermines her point in this slide...
Reposted by mac64.bsky.social
kids.
We have literally had HBV outbreaks occur in daycares.
www.sciencedirect.com/science/arti...
It is also transmissible by human bites:
academic.oup.com/jid/article/....
We have literally had HBV outbreaks occur in daycares.
www.sciencedirect.com/science/arti...
It is also transmissible by human bites:
academic.oup.com/jid/article/....
Horizontal transmission of hepatitis B in a children's day-care centre: a preventable event
Using molecular finger-printing, we provided evidence that, in a children's day-care centre, a known hepatitis B virus (HBV) hepatitis B e antigen (HB…
www.sciencedirect.com
December 4, 2025 at 2:29 PM
kids.
We have literally had HBV outbreaks occur in daycares.
www.sciencedirect.com/science/arti...
It is also transmissible by human bites:
academic.oup.com/jid/article/....
We have literally had HBV outbreaks occur in daycares.
www.sciencedirect.com/science/arti...
It is also transmissible by human bites:
academic.oup.com/jid/article/....
Reposted by mac64.bsky.social
As a reminder, today's meeting is all about hepatitis B (HBV) vaccination, specifically the dose of vaccine given within 24 hours of birth universally. This is a critically important policy intervention that enabled us to drastically reduce the incidence of hepatitis B:
www.cdc.gov/mmwr/volumes...
www.cdc.gov/mmwr/volumes...
December 4, 2025 at 1:16 PM
As a reminder, today's meeting is all about hepatitis B (HBV) vaccination, specifically the dose of vaccine given within 24 hours of birth universally. This is a critically important policy intervention that enabled us to drastically reduce the incidence of hepatitis B:
www.cdc.gov/mmwr/volumes...
www.cdc.gov/mmwr/volumes...
Reposted by mac64.bsky.social
The slides clearly show that the vast majority of parents accept the birth dose of hepatitis B vaccine.
Pebsworth presents data showing the prevalence of HBV by country, saying that the US is an outlier among countries with similar incidence.
That's because the universal birth dose worked.
Pebsworth presents data showing the prevalence of HBV by country, saying that the US is an outlier among countries with similar incidence.
That's because the universal birth dose worked.
December 4, 2025 at 1:51 PM
The slides clearly show that the vast majority of parents accept the birth dose of hepatitis B vaccine.
Pebsworth presents data showing the prevalence of HBV by country, saying that the US is an outlier among countries with similar incidence.
That's because the universal birth dose worked.
Pebsworth presents data showing the prevalence of HBV by country, saying that the US is an outlier among countries with similar incidence.
That's because the universal birth dose worked.
Reposted by mac64.bsky.social
offering a potentially transformative tool for global cervical cancer prevention.
www.cidrap.umn.edu/human-papill...
www.cidrap.umn.edu/human-papill...
Single HPV vaccine dose matches protection of 2-dose regimen, new trial shows
www.cidrap.umn.edu
December 4, 2025 at 2:09 PM
offering a potentially transformative tool for global cervical cancer prevention.
www.cidrap.umn.edu/human-papill...
www.cidrap.umn.edu/human-papill...
Reposted by mac64.bsky.social
It’s wrong to not have novavax in Canada. It’s a great vaccine and sometimes, people’s only option.
December 4, 2025 at 1:06 PM
It’s wrong to not have novavax in Canada. It’s a great vaccine and sometimes, people’s only option.
Reposted by mac64.bsky.social
Dear Mr Carney,
COVID-19 continues to mutate, circulate, infect, and disable (through long-covid). One of my Jr High patients got disabled by long-covid this year.
Please implement a national clean indoor air strategy for all bldgs., airplanes, trains, buses, and more to prevent covid. Call me.
COVID-19 continues to mutate, circulate, infect, and disable (through long-covid). One of my Jr High patients got disabled by long-covid this year.
Please implement a national clean indoor air strategy for all bldgs., airplanes, trains, buses, and more to prevent covid. Call me.
December 4, 2025 at 3:34 AM
Dear Mr Carney,
COVID-19 continues to mutate, circulate, infect, and disable (through long-covid). One of my Jr High patients got disabled by long-covid this year.
Please implement a national clean indoor air strategy for all bldgs., airplanes, trains, buses, and more to prevent covid. Call me.
COVID-19 continues to mutate, circulate, infect, and disable (through long-covid). One of my Jr High patients got disabled by long-covid this year.
Please implement a national clean indoor air strategy for all bldgs., airplanes, trains, buses, and more to prevent covid. Call me.
Reposted by mac64.bsky.social
News framing casts this as another “experts disagree” moment.
But this disagreement isn’t really about prostate screening at all.
It's epistemic.
The real problem is a structural failure in the machinery that produces our screening guidelines.
(1/2)
But this disagreement isn’t really about prostate screening at all.
It's epistemic.
The real problem is a structural failure in the machinery that produces our screening guidelines.
(1/2)
December 4, 2025 at 3:40 AM
News framing casts this as another “experts disagree” moment.
But this disagreement isn’t really about prostate screening at all.
It's epistemic.
The real problem is a structural failure in the machinery that produces our screening guidelines.
(1/2)
But this disagreement isn’t really about prostate screening at all.
It's epistemic.
The real problem is a structural failure in the machinery that produces our screening guidelines.
(1/2)
Reposted by mac64.bsky.social
They were there to watch him sign a regressive order to get rid of EV advantages, and reduce gas mileage requirements.
December 4, 2025 at 4:03 AM
They were there to watch him sign a regressive order to get rid of EV advantages, and reduce gas mileage requirements.
Reposted by mac64.bsky.social
And by stopping staff from criticising this approach externally they squash dissenting voices. This is not ethical or scientific practice. Thanks to @duncanrobertson.bsky.social for sharing. Full article here:
A Threat to Evidence-Based Vaccine Policy and Public Health Security at the FDA | NEJM
Twelve former commissioners of the FDA express concern that the agency’s recent moves
will undermine a regulatory model designed to ensure vaccine safety, effectiveness,
and availability.
www.nejm.org
December 4, 2025 at 9:28 AM
And by stopping staff from criticising this approach externally they squash dissenting voices. This is not ethical or scientific practice. Thanks to @duncanrobertson.bsky.social for sharing. Full article here:
Reposted by mac64.bsky.social
Eg People can claim the vaccine made them into a frog and it can go on the VAERs record so basically it’s not reliable data at all without further validation. Using this data they claim 10 infants died weeks after a Covid vaccine but they won’t share the data yet propose sweeping changes in policy
December 4, 2025 at 9:28 AM
Eg People can claim the vaccine made them into a frog and it can go on the VAERs record so basically it’s not reliable data at all without further validation. Using this data they claim 10 infants died weeks after a Covid vaccine but they won’t share the data yet propose sweeping changes in policy
Reposted by mac64.bsky.social
This means now Booster formulation vaccines would take longer to get through trials and regulations and be more costly as a result. They also may not be available when needed - effectively making them redundant
December 4, 2025 at 9:28 AM
This means now Booster formulation vaccines would take longer to get through trials and regulations and be more costly as a result. They also may not be available when needed - effectively making them redundant
Reposted by mac64.bsky.social
Booster vaccines that require annual updates will have to go through rigorous clinical trials- currently as formulation is a tweak for antigen only, the basic vaccine been shown to be safe and they are needed so quickly that data on how well they stimulate immunity is used
December 4, 2025 at 9:28 AM
Booster vaccines that require annual updates will have to go through rigorous clinical trials- currently as formulation is a tweak for antigen only, the basic vaccine been shown to be safe and they are needed so quickly that data on how well they stimulate immunity is used
Reposted by mac64.bsky.social
Firstly FDA staff are to be banned from discussing their takes on science evidence re vaccines until the decision made in private within FDA. This removes transparency about decision making, reduces trust as none can see how conclusions are made.
December 4, 2025 at 9:28 AM
Firstly FDA staff are to be banned from discussing their takes on science evidence re vaccines until the decision made in private within FDA. This removes transparency about decision making, reduces trust as none can see how conclusions are made.
Reposted by mac64.bsky.social
The CEOs of Ford and Stellantis, as well as senior executives from other auto manufacturers, standing beside him while Trump goes off on another vicious racist rant about African immigrants. Not one of them had the courage or the dignity to walk away.
bsky.app/profile/just...
bsky.app/profile/just...
Trump, continued: "What the Somalian people have done to Minnesota is not even believable. It’s not even believable. And a lot of it starts with the governor. A lot of it starts with Barack HUSSEIN Obama, because that’s when people started coming in... They want to kiss our country good night."
December 3, 2025 at 11:10 PM
The CEOs of Ford and Stellantis, as well as senior executives from other auto manufacturers, standing beside him while Trump goes off on another vicious racist rant about African immigrants. Not one of them had the courage or the dignity to walk away.
bsky.app/profile/just...
bsky.app/profile/just...
Reposted by mac64.bsky.social
Egg producers suspect bird flu is traveling through the air.
After a disastrous Midwestern outbreak early this year, we tested that theory and found that where the wind blew, the virus followed.
Vaccines could help, but the USDA hasn’t approved them.
After a disastrous Midwestern outbreak early this year, we tested that theory and found that where the wind blew, the virus followed.
Vaccines could help, but the USDA hasn’t approved them.
What the U.S. Government Is Dismissing That Could Seed a Bird Flu Pandemic
Egg producers suspect bird flu is traveling through the air. After a disastrous Midwestern outbreak early this year, we tested that theory and found that where the wind blew, the virus followed. Vacci...
www.propublica.org
December 4, 2025 at 2:30 AM
Egg producers suspect bird flu is traveling through the air.
After a disastrous Midwestern outbreak early this year, we tested that theory and found that where the wind blew, the virus followed.
Vaccines could help, but the USDA hasn’t approved them.
After a disastrous Midwestern outbreak early this year, we tested that theory and found that where the wind blew, the virus followed.
Vaccines could help, but the USDA hasn’t approved them.
Reposted by mac64.bsky.social
And as they exclude experts - it's a matter of faith that an EBM-trained MD with a checklist doesn't need expertise to evaluate science from any field - EBM/GRADE processes are full of garbage. You can't find mistakes you don't understand. Even McMaster-GRADE+Cochrane+$9M can't make GRADE rigorous.
The 3rd annual Canadian Long COVID symposium wrapped up yesterday. It was a great meeting, and I got some nice news at the end!
PDF of the poster is here: www.dropbox.com/scl/fi/e8wh6...
MP3 of a 5-minute verbal overview is here: www.dropbox.com/scl/fi/ej0lw...
PDF of the poster is here: www.dropbox.com/scl/fi/e8wh6...
MP3 of a 5-minute verbal overview is here: www.dropbox.com/scl/fi/ej0lw...
November 16, 2025 at 9:38 AM
And as they exclude experts - it's a matter of faith that an EBM-trained MD with a checklist doesn't need expertise to evaluate science from any field - EBM/GRADE processes are full of garbage. You can't find mistakes you don't understand. Even McMaster-GRADE+Cochrane+$9M can't make GRADE rigorous.
Reposted by mac64.bsky.social
And they are only getting started. When US medical guidance says vaccines (or now Tylenol) cause autism, measles is good for you, COVID's not airborne, that's all EBM/GRADE. He who picks the pickers, picks the cherries. They're starting with the NIH, but this plan is being applied to all US science.
The roadmap for turning the NIH into an EBM slush fund and shutting down real science. Kulldorf, in the new public health blog ("journal") co-founded by Bhattacharya.
1: Fund based on who applies 🤔, rather than ideas
2: Give ECR grants. But only to "medical, dental and public health school".
1: Fund based on who applies 🤔, rather than ideas
2: Give ECR grants. But only to "medical, dental and public health school".
November 16, 2025 at 9:35 AM
And they are only getting started. When US medical guidance says vaccines (or now Tylenol) cause autism, measles is good for you, COVID's not airborne, that's all EBM/GRADE. He who picks the pickers, picks the cherries. They're starting with the NIH, but this plan is being applied to all US science.
Reposted by mac64.bsky.social
'...said he was more qualified to analyze COVID-19 data than the 1,700 scientists at the agency.
“None of those people have my skills,” Dr. Alexander said. “I make the judgment whether this is crap.”'
Is just perfectly bang-on with the way EBM has handled COVID and aerosol transmission from day 1.
“None of those people have my skills,” Dr. Alexander said. “I make the judgment whether this is crap.”'
Is just perfectly bang-on with the way EBM has handled COVID and aerosol transmission from day 1.
McMaster professor embroiled in White House controversy over reports he attempted to muzzle scientists
Paul Elias Alexander, a scientific adviser to Health and Human Services spokesman Michael Caputo, blasted CDC staff for coming out with reports that contradicted President Donald Trump’s views on COVI...
www.theglobeandmail.com
April 17, 2025 at 5:43 PM
'...said he was more qualified to analyze COVID-19 data than the 1,700 scientists at the agency.
“None of those people have my skills,” Dr. Alexander said. “I make the judgment whether this is crap.”'
Is just perfectly bang-on with the way EBM has handled COVID and aerosol transmission from day 1.
“None of those people have my skills,” Dr. Alexander said. “I make the judgment whether this is crap.”'
Is just perfectly bang-on with the way EBM has handled COVID and aerosol transmission from day 1.
Reposted by mac64.bsky.social
If anyone's wondering, that'd be this Paul Alexander, an advisor under Trump I to the same HHS now run by RFK under Trump II - advocating for the same "let COVID rip" strategy proposed in the Great Barrington Declaration (whose 3 authors included...Bhattacharya and Kulldorf - see thread above).
‘We want them infected’: Trump appointee demanded ‘herd immunity’ strategy, emails reveal
Then-HHS science adviser Paul Alexander called for millions of Americans to be infected as means of fighting Covid-19.
www.politico.com
April 17, 2025 at 5:43 PM
If anyone's wondering, that'd be this Paul Alexander, an advisor under Trump I to the same HHS now run by RFK under Trump II - advocating for the same "let COVID rip" strategy proposed in the Great Barrington Declaration (whose 3 authors included...Bhattacharya and Kulldorf - see thread above).
Reposted by mac64.bsky.social
OK this is ridiculous. The draft new Canadian public health guidance-development mechanism doubles down on excluding subject matter experts from voting roles, restricts membership to people from inside the EBM pseudoscience bubble, and sets up to funnel public money to McMaster-GRADE courses etc.
Draft Implementation Plan for the Renewed Canadian Task Force on Preventive Health Care - Canada.ca
Feedback will help ensure effective implementation of the recommendations from the External Expert Review and inform a renewed Task Force.
www.canada.ca
November 16, 2025 at 9:26 AM
OK this is ridiculous. The draft new Canadian public health guidance-development mechanism doubles down on excluding subject matter experts from voting roles, restricts membership to people from inside the EBM pseudoscience bubble, and sets up to funnel public money to McMaster-GRADE courses etc.
Reposted by mac64.bsky.social
The Trump administration plans to block Democratic-controlled states from accessing billions of dollars they need to run their food stamp programs unless governors turn over benefits rolls to federal officials.
Trump administration will block SNAP management funds for blue states
Agriculture Secretary Brooke Rollins said officials won’t send money to administer food stamps to states that don’t share information about benefits recipients with the federal government.
www.washingtonpost.com
December 2, 2025 at 10:00 PM
The Trump administration plans to block Democratic-controlled states from accessing billions of dollars they need to run their food stamp programs unless governors turn over benefits rolls to federal officials.
Reposted by mac64.bsky.social
3/ W/o intervention, ~85% of infants born to infected mothers become infected, 90% of whom develop chronic HBV (vs <5% of adults).
1 in 4 children with HBV die prematurely from cirrhosis or liver cancer
Annual treatment for chronic HBV = $25-$325k
Prevention is key
www.cdc.gov/acip/downloa...
1 in 4 children with HBV die prematurely from cirrhosis or liver cancer
Annual treatment for chronic HBV = $25-$325k
Prevention is key
www.cdc.gov/acip/downloa...
December 2, 2025 at 8:32 PM
3/ W/o intervention, ~85% of infants born to infected mothers become infected, 90% of whom develop chronic HBV (vs <5% of adults).
1 in 4 children with HBV die prematurely from cirrhosis or liver cancer
Annual treatment for chronic HBV = $25-$325k
Prevention is key
www.cdc.gov/acip/downloa...
1 in 4 children with HBV die prematurely from cirrhosis or liver cancer
Annual treatment for chronic HBV = $25-$325k
Prevention is key
www.cdc.gov/acip/downloa...
Reposted by mac64.bsky.social
2/ Universal HBV vaccination within 24 hours of birth has worked incredibly well to safely protect infants from lifelong hep B infection.
CDC surveillance data (2008-2023) show that among those age 0-19 (the cohort protected by universal HBV-BD) acute hep B rates have been ZERO since 2011.
CDC surveillance data (2008-2023) show that among those age 0-19 (the cohort protected by universal HBV-BD) acute hep B rates have been ZERO since 2011.
December 2, 2025 at 8:32 PM
2/ Universal HBV vaccination within 24 hours of birth has worked incredibly well to safely protect infants from lifelong hep B infection.
CDC surveillance data (2008-2023) show that among those age 0-19 (the cohort protected by universal HBV-BD) acute hep B rates have been ZERO since 2011.
CDC surveillance data (2008-2023) show that among those age 0-19 (the cohort protected by universal HBV-BD) acute hep B rates have been ZERO since 2011.