Congrats, Arindam!! Great news!! 🤩🥳

Thanks!!

Juliii ❤️ thanks for your kind words!! Looking forward to be part of the wonderful optics community in Argenitna!!

Thread describing our work: bsky.app/profile/luma...

Thank you, Inês! 😀

I am also very grateful to my previous mentors, Ralf Jungmann and Fernando D. Stefani, and many other amazing colleagues who have supported me throughout my career.

I am very grateful to Gabriel Rabinovich for his generous sponsorship and guidance throughout the application process, and I look forward to developing my research program within the stimulating environment of the Glycosciences Program at IBYME.

I’ll soon be looking for Master’s students, PhD students, and a postdoc to join the team—so if this sounds exciting to you, please don’t hesitate to reach out!

My research will focus on deciphering cell signaling at the molecular level by applying and developing cutting-edge super-resolution methods, with a particular emphasis on glycoimmune checkpoints, aiming to translate this knowledge into novel and improved therapies.

This grant gives me the opportunity to start building my own group, with support for setting up a state-of-the-art super-resolution microscopy lab.

Within this neuronal atlas we can reveal the three synapse classes, excitatory, inhibitory and the recently discovered mixed synapse. Organelle imaging of Peroxisomes (Pmp70) and the Golgi Apparatus (Golga5) reveals rare contact sides and even fused particles. (5/6)

To show the power of the technique, we acquired a 13-plex 200 x 200 µm2 neuronal atlas in 3D. With this atlas we map the interaction architecture of three neurons, resolving organelles, cytoskeleton, vesicles and synapses at single-protein resolution. (4/6)

We demonstrate speed-optimized left-handed DNA-PAINT by characterizing the sequence binding kinetics and resolving three main microscopy benchmarking targets, mitochondria, microtubules and nuclear pore complexes with <5 nm localization precision. (3/6)

The mirrored design of left-handed oligonucleotides allows the extension of the common 6 speed-sequences R1-R6 with their analogs L1-L6, enabling 12 target multiplexing with a standard secondary label-free DNA-PAINT workflow. (2/6)

Congratulations, Rita! And thanks for all the amazing work at Nature Methods!

Thanks so much, Mahipal!!