@lizdkim.bsky.social
Reposted
1/14
Happy (but mostly relieved) to share my dream project with @boudkerlab.bsky.social, now published in @natsmb.nature.com! We used evolution, protein engineering & cryoEM to uncover how ion coupling in glutamate transporters works, and how it evolved.🧵
Free article: go.nature.com/4oRUC1q
Happy (but mostly relieved) to share my dream project with @boudkerlab.bsky.social, now published in @natsmb.nature.com! We used evolution, protein engineering & cryoEM to uncover how ion coupling in glutamate transporters works, and how it evolved.🧵
Free article: go.nature.com/4oRUC1q
Evolutionary analysis reveals the origin of sodium coupling in glutamate transporters - Nature Structural & Molecular Biology
Reddy et al. used ancestral protein reconstruction, cryo-electron microscopy and functional assays to elucidate how a secondary active transporter evolved to harness the energy of sodium gradients to ...
go.nature.com
September 12, 2025 at 12:08 AM
1/14
Happy (but mostly relieved) to share my dream project with @boudkerlab.bsky.social, now published in @natsmb.nature.com! We used evolution, protein engineering & cryoEM to uncover how ion coupling in glutamate transporters works, and how it evolved.🧵
Free article: go.nature.com/4oRUC1q
Happy (but mostly relieved) to share my dream project with @boudkerlab.bsky.social, now published in @natsmb.nature.com! We used evolution, protein engineering & cryoEM to uncover how ion coupling in glutamate transporters works, and how it evolved.🧵
Free article: go.nature.com/4oRUC1q
Reposted
A new paper from the #MacKinnonLab in @pnas.org finds that while Kv2.1 and EAG1 are from distinct architectural classes of voltage-dependent ion channels, the way the voltage sensors gate their pores is very similar. #RockefellerScience
Electric field–induced pore constriction in the human Kv2.1 channel | PNAS
Gating in voltage-dependent ion channels is regulated by the transmembrane voltage.
This form of regulation is enabled by voltage-sensing domains (...
www.pnas.org
May 19, 2025 at 3:56 PM
A new paper from the #MacKinnonLab in @pnas.org finds that while Kv2.1 and EAG1 are from distinct architectural classes of voltage-dependent ion channels, the way the voltage sensors gate their pores is very similar. #RockefellerScience
Reposted
For #CysticFibrosisAwarenessMonth, we’re spotlighting the science that helped make today’s treatments possible.
Jue Chen’s research reveals how small molecules rescue misfolded CFTR proteins — a breakthrough in cystic fibrosis therapy.
Jue Chen’s research reveals how small molecules rescue misfolded CFTR proteins — a breakthrough in cystic fibrosis therapy.
May 9, 2025 at 12:08 PM
For #CysticFibrosisAwarenessMonth, we’re spotlighting the science that helped make today’s treatments possible.
Jue Chen’s research reveals how small molecules rescue misfolded CFTR proteins — a breakthrough in cystic fibrosis therapy.
Jue Chen’s research reveals how small molecules rescue misfolded CFTR proteins — a breakthrough in cystic fibrosis therapy.
Reposted
How do we taste sweetness?
HHMI Investigator Charles Zuker’s lab at @columbiauniversity.bsky.social just revealed the structure of the human sweet receptor. This discovery could help cut sugar without cutting taste—unlocking big possibilities for the future of food.
Read more: hhmi.news/3F0plr4
HHMI Investigator Charles Zuker’s lab at @columbiauniversity.bsky.social just revealed the structure of the human sweet receptor. This discovery could help cut sugar without cutting taste—unlocking big possibilities for the future of food.
Read more: hhmi.news/3F0plr4
May 8, 2025 at 1:04 PM
How do we taste sweetness?
HHMI Investigator Charles Zuker’s lab at @columbiauniversity.bsky.social just revealed the structure of the human sweet receptor. This discovery could help cut sugar without cutting taste—unlocking big possibilities for the future of food.
Read more: hhmi.news/3F0plr4
HHMI Investigator Charles Zuker’s lab at @columbiauniversity.bsky.social just revealed the structure of the human sweet receptor. This discovery could help cut sugar without cutting taste—unlocking big possibilities for the future of food.
Read more: hhmi.news/3F0plr4
Reposted
A Nature analysis shows the 25 highest-cited papers published in the 21st Century and explores why they are breaking records. #Academicsky 🧪
Exclusive: the most-cited papers of the twenty-first century
A Nature analysis reveals the 25 highest-cited papers published this century and explores why they are breaking records.
go.nature.com
April 16, 2025 at 4:26 PM
A Nature analysis shows the 25 highest-cited papers published in the 21st Century and explores why they are breaking records. #Academicsky 🧪
Reposted
Ball-and-chain inactivation of a human large conductance calcium-activated potassium channel pubmed.ncbi.nlm.nih.gov/39971906/ #cryoem
February 20, 2025 at 10:28 AM
Ball-and-chain inactivation of a human large conductance calcium-activated potassium channel pubmed.ncbi.nlm.nih.gov/39971906/ #cryoem
Reposted
Congratulations to the 2025 Cole Award Winners!
***Dan Minor, Baron Chanda and Crina Nimigean***
All gave inspiring talks, shared their journeys and celebrated trainees/collaborators. @biophysicalsoc.bsky.social
***Dan Minor, Baron Chanda and Crina Nimigean***
All gave inspiring talks, shared their journeys and celebrated trainees/collaborators. @biophysicalsoc.bsky.social
February 17, 2025 at 5:31 PM
Congratulations to the 2025 Cole Award Winners!
***Dan Minor, Baron Chanda and Crina Nimigean***
All gave inspiring talks, shared their journeys and celebrated trainees/collaborators. @biophysicalsoc.bsky.social
***Dan Minor, Baron Chanda and Crina Nimigean***
All gave inspiring talks, shared their journeys and celebrated trainees/collaborators. @biophysicalsoc.bsky.social
Reposted
Huge congrats to the 2025 Cole Award winners from @biophysicalsoc.bsky.social to
@Baron Chanda
@Daniel Minor
@Crina Nimigean
#ionchannels #biophysics #electrophysiology #membranes #signaltransduction #science #scientists
@Baron Chanda
@Daniel Minor
@Crina Nimigean
#ionchannels #biophysics #electrophysiology #membranes #signaltransduction #science #scientists
congratulations greeting card with a group of hands
ALT: congratulations greeting card with a group of hands
media.tenor.com
December 16, 2024 at 6:42 PM
Huge congrats to the 2025 Cole Award winners from @biophysicalsoc.bsky.social to
@Baron Chanda
@Daniel Minor
@Crina Nimigean
#ionchannels #biophysics #electrophysiology #membranes #signaltransduction #science #scientists
@Baron Chanda
@Daniel Minor
@Crina Nimigean
#ionchannels #biophysics #electrophysiology #membranes #signaltransduction #science #scientists