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livuni-ismib.bsky.social
Institute of Systems, Molecular and Integrative Biology
@livuni-ismib.bsky.social
300 followers 110 following 40 posts
Cutting-edge, interdisciplinary research and teaching in the biological sciences at the University of Liverpool. #TeamLivUni

💻 liverpool.ac.uk/systems-molecular-and-integrative-biology
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livuni-ismib.bsky.social
Institute of Systems, Molecular and Integrative Biology @livuni-ismib.bsky.social · Nov 20
👋 Hello friends old and new! We're excited to share all the latest news and updates from our brilliant institute here at the University of Liverpool! Stay tuned! 💜
livuni-ismib.bsky.social
New clinical tool developed by @liverpooluni.bsky.social and The Walton Centre shown to accurately predict whether meningiomas will grow or cause symptoms, helping doctors and patients make better-informed treatment decisions.

🔗 bit.ly/47QP6G4

#TeamLivUni | #braintumour
A navy blue title card that reads ' New tool helps predict which brain tumours will require treatment' in white text. Pictured to the left is a transparent human body image that shows the brain.
November 21, 2025 at 2:41 PM
Reposted by Institute of Systems, Molecular and Integrative Biology
ainhoamielgo.bsky.social
⭐️ Fantastic talk from Evangelos Giampazolias today at our Liverpool Cancer Seminar Series on nutrient-host-microbiome interactions in cancer immunity 👏🏻👏🏻
@livuni-ismib.bsky.social
@livunicancer.bsky.social
@cruk-mi.bsky.social
@giampazolias.bsky.social
November 18, 2025 at 4:39 PM
Reposted by Institute of Systems, Molecular and Integrative Biology
livuniresearch.bsky.social
@liverpooluni.bsky.social and @newcastleuni.bsky.social researchers have uncovered how bacterial organelles assemble, opening new routes for bioengineering and climate innovation.

👉 news.liverpool.ac.uk/2025/11/10/n...
November 14, 2025 at 12:43 PM
Reposted by Institute of Systems, Molecular and Integrative Biology
livunicancer.bsky.social
Join a dynamic research team led by Dr Carrie Duckworth -
2 PhD fully funded studentships are available aligned with the recently established North West Cancer Research gastric cancer organoid hub!

#Biotechnology #BioEngineering #PhDpositions
#CellBiology #CancerBiology
November 15, 2025 at 2:52 PM
Reposted by Institute of Systems, Molecular and Integrative Biology
danielrigden.bsky.social
Fully-funded PhD opportunities to tell you about at @livuni-ismib.bsky.social

1. I'm leading a project to translate protein bioinformatics tools to make the lives of structural biologists easier. Your supervisory team includes Igor Barsukov, Ronan Keegan and David McDonagh

lnkd.in/ePaFHGZD
November 12, 2025 at 9:03 AM
Reposted by Institute of Systems, Molecular and Integrative Biology
bengoult.bsky.social
🧠 Fully funded 4-year PhD studentship 🧠 Please repost

BBSRC NWD project with @parikki.bsky.social and @iamabyron.bsky.social

Come join us to look at how mechanical and oxidative stress signalling pathways converge on the synaptic scaffold protein talin.

www.findaphd.com/phds/project...
(BBSRC NWD) A novel redox mechanosignalling nexus in the synapse that is misregulated in neurodegeneration at University of Liverpool on FindAPhD.com
PhD Project - (BBSRC NWD) A novel redox mechanosignalling nexus in the synapse that is misregulated in neurodegeneration at University of Liverpool, listed on FindAPhD.com
www.findaphd.com
November 11, 2025 at 10:29 AM
livuni-ismib.bsky.social
NEWS | North West Cancer Research supports study to improve gastric cancer outcomes

The project led by Dr Carrie Duckworth, entitled OrganoXplore, aims to develop personalised treatment strategies to reduce deaths from gastric cancer

🔗 bit.ly/4osEqTO

#TeamLivUni
A photo from left to right of Mr Mushfique Alam, Dr Georges Chalhoub, Dr Carrie Duckworth, Mr Nathan Stephens and Professor Mark Pritchard in front of a 'Faculty of Health and Life Sciences' branded wall.
November 11, 2025 at 12:06 PM
Reposted by Institute of Systems, Molecular and Integrative Biology
impeiyee.bsky.social
Our latest preprint is out!
We developed an inducible “RapTag” system that uses ENTAC to chemically recruit USP15 to the unstable protein CTLA4. This induced proximity stabilises and slows down the rapid lysosomal turnover of CTLA4.
@livuni-ismib.bsky.social
www.biorxiv.org/content/10.1...
Targeted recruitment of USP15 enhances CTLA4 surface levels and restricts its degradation.
Induced protein proximity offers powerful new routes to modulate protein fate. While proteolysis-targeting chimeras (PROTACs) promote degradation through E3 ligase recruitment, the converse principle-...
www.biorxiv.org
November 10, 2025 at 4:34 PM
Reposted by Institute of Systems, Molecular and Integrative Biology
livuniresearch.bsky.social
@liverpooluni.bsky.social and CyanoCapture Ltd are joining forces to develop the next generation of carboxysome-based targeted drug delivery systems, exploiting unique traits found in fast-growing cyanobacteria.

Read more 👉

news.liverpool.ac.uk/2025/10/30/p...
Partnership with CyanoCapture Ltd to develop bionanotechnology for targeted drug delivery - University of Liverpool News
Partnership with CyanoCapture Ltd to develop bionanotechnology for targeted drug delivery
news.liverpool.ac.uk
October 31, 2025 at 4:36 PM
Reposted by Institute of Systems, Molecular and Integrative Biology
chrisgoldring.bsky.social
Our group in @livuni-ismib.bsky.social are delighted to share our latest article in Nature Reviews Drug Discovery:
lnkd.in/d_uXvxM2
In quantitative systems toxicology, the achievements of the @IHIeurope.bsky.social Innovative Health Initiative TransQST consortium in improving drug safety.
LinkedIn
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lnkd.in
October 29, 2025 at 3:25 PM
livuni-ismib.bsky.social
NEWS | A major UK-wide study led by Dr Carolyn Young has revealed the profound impact of multiple sclerosis on health-related quality of life, with findings that could reshape how services and resources are allocated for people living with the condition

🔗 bit.ly/4qBhovG

#TeamLivUni
October 28, 2025 at 2:38 PM
livuni-ismib.bsky.social
The BBSRC NorthWest DTP has welcomed its first postgraduate cohort. The programme is a joint initiative by @liverpooluni.bsky.social and @manchester.ac.uk to equip early-career scientists with the skills to tackle the UK’s key bioscience and environmental challenges.

🔗 bit.ly/48JGwK4

#TeamLivUni
A teal news title card that reads 'BBSRC Northwest doctoral programme in biosciences welcomes first cohort’ in white text. Pictured in the top right is a photo of the 31 new students at the programme launch event.
October 27, 2025 at 2:06 PM
Reposted by Institute of Systems, Molecular and Integrative Biology
wanyuac.bsky.social
Celebrating the first wet-lab experiment in my group. Successfully carried out by Sophie, my first MRes student and research assistant in Liverpool @liverpooluni.bsky.social, and me. Thanks to colleagues in the APT group of ISMIB @livuni-ismib.bsky.social for sharing their experience. #nanopore
Photo in my lab
October 24, 2025 at 6:05 PM
Reposted by Institute of Systems, Molecular and Integrative Biology
drlaurarandle.bsky.social
Great to share our British Science Festival experience ‘Liverpool’s Party People’ with @livuni-ismib.bsky.social colleagues this afternoon.

Thanks @drlornayoung.bsky.social for the photo
October 22, 2025 at 5:31 PM
Reposted by Institute of Systems, Molecular and Integrative Biology
livunihls.bsky.social
Congratulations to Konstantinos Prokopidis from @livuni-ilcams.bsky.social and Theano Kyriakou from @livuni-ismib.bsky.social, who have received the prestigious Professor John Glover Memorial Award 🎉

➡️ bit.ly/42wwOXI

#TeamLivUni
A collage of two photos of PhD students Konstantinos Prokopidis (pictured left) and Theano Kyriakou (pictured right) from the Faculty of Health and Life Sciences.
October 15, 2025 at 2:16 PM
livuni-ismib.bsky.social
NEWS | Congratulations to Dr Joshua Gardner, who has received a five-year @wellcometrust.bsky.social Early-Career Award to support his research into how prior exposure to viruses can impact vaccine safety and performance

➡️ bit.ly/4mSKbbR

#TeamLivUni
A sky blue quote social card that reads ‘“We hope that through targeted viral engineering, this work has the potential to broaden therapeutic applications, improve efficacy and underpin the development of the next generation of vaccines and gene therapies.” Dr Joshua Gardner, Department of Pharmacology and Therapeutics’ in white text. Pictured to the left is a photograph of Dr Joshua Gardner.
October 10, 2025 at 1:33 PM
livuni-ismib.bsky.social
NEWS | New research has shown significant global variation in the treatment of diverticulitis, a common bowel condition.

The Bowel Research UK funded study revealed the use of antibiotics to treat diverticulitis is 'alarmingly high'.

➡️ bit.ly/4gRjxPn

#TeamLivUni
Alt text: A navy blue news title card that reads 'Significant global variation in the treatment of common bowel condition' in white text against a transparent image of a man clutching his abdomen.
October 3, 2025 at 9:43 AM
livuni-ismib.bsky.social
New research has revealed how pathogenic bacteria construct tiny protein-based compartments, offering new insight into how bacteria survive and thrive in the gut.

➡️ bit.ly/476v5uz

#TeamLivUni
Alt text: A navy blue news title card that reads 'New insights into how pathogens build protein machinery for survival in the gut' in white writing. Pictured to the right is a diagram of the digestive system with diagrams of gut bacteria.
October 3, 2025 at 9:30 AM
Reposted by Institute of Systems, Molecular and Integrative Biology
livuninews.bsky.social
NEWS I Scientists at @liverpooluni.bsky.social have developed a new low-cost blood test that could make it easier to detect #Alzheimer’s disease at an earlier stage. Read all about it ⬇️

news.liverpool.ac.uk/2025/10/01/l...

@livunihls.bsky.social @livuni-ismib.bsky.social
October 1, 2025 at 11:18 AM
Reposted by Institute of Systems, Molecular and Integrative Biology
livunicancer.bsky.social
Join us for coffee & cake 🍰 ☕
Macmillan Coffee Morning
Friday 26 September
10:00 - 11:00
2nd floor breakout area, William Henry Duncan Building

Raising funds for Macmillan Cancer Support. There will be tea, coffee and a variety of cakes and other treats to enjoy together.
September 25, 2025 at 11:48 AM
Reposted by Institute of Systems, Molecular and Integrative Biology
livunicancer.bsky.social
We have an ISMIB seminar today Thursday 25th September, 13:00-14:00 - please join us :-)

Guest Speaker – Professor Paul Taylor
Title - “Insights into Human Health through Studies of Molecular Evolution”
Host – Bernadette Moore
Location – Physiology Seminar Room, Nuffield Building
September 25, 2025 at 7:44 AM
Reposted by Institute of Systems, Molecular and Integrative Biology
rebee.bsky.social
THIS WEEK!!!!!

Come learn about viruses 🦠😍

@antiviral-rskating.bsky.social
@livuni-ismib.bsky.social
@livuni-ives.bsky.social
@britsciassoc.bsky.social
antiviral-rskating.bsky.social Antiviral Roller Skating @antiviral-rskating.bsky.social · Sep 4
Just over ONE WEEK to go and things are really coming together!
Here's a look at some fun we've been having preparing for #BSF25 next week! 🎀🧬🦠✨️
📸: @rebee.bsky.social

@britsciassoc.bsky.social
@livuninews.bsky.social
@microbiologysociety.bsky.social

#scicomm
#rollerderby
#rollerskating
Greyscale virus background with a photo in a lilac border in the middle showing Debs waving a yellow ribbon emphatically whilst three other skaters, Elle, Helen and Hannah (left to right) in the background giggles. A white speech bubble from Hannah is in the top right saying "She's at it with the ribbon again. guys" Greyscale virus background with a photo in a purple border with Hannah, wearing all black, laughing and holding a purple and a yellow ribbon in each hand. Lynn is in the background laughing with her hand over her mouth. A white speech bubble is coming from Hannah saying "Oh wait, guys, aive seen the light. Ribbon joy forever!" A greyscale background with Debs and Imogen both smiling with their eyes closed and hands on their hips, facing each other. 3 purple cartoon viruses are dotted around the photo and a white text bubble coming from Imogen says "wow, can't believe we get to have so much fun learning about viruses & antivirals!" Beneath the photo it says "this could be you at..." followed by a lilac and white sketch style arrow pointing right to the next slide. A greyscale background with a photo of Ani leading the choreography of a group of five skaters holding hands in a circle. The text above the photo reads "Antiviral Roller Skating @ British Science Festival 2025. Below the photo the text reads "Friday 12th September, 18:30, Unity Theatre - Theatre One
September 10, 2025 at 7:55 AM
Reposted by Institute of Systems, Molecular and Integrative Biology
benedictneuro.bsky.social
Excellent 1st LINC #Neuroscience Seminar from Prof Jenkinson, Mr Nish Srikandaraja & Mr Ali Baksh on #Neurosurgery #research focusing on #meningioma & #spinal

Follow us for our monthly series: @lincneurosci.bsky.social

@liverpooluni.bsky.social @livuni-ismib.bsky.social @livuni-ives.bsky.social
September 3, 2025 at 1:40 PM
Reposted by Institute of Systems, Molecular and Integrative Biology
livunicancer.bsky.social
Welcome to September!

Tomorrow Tues 2nd September '25, 1-2pm

Dr Yuewei Xu (Academy of Pharmacy⭐️, XJTLU, China).

Presents "RNA splicing – gateway to cancer vulnerabilities"

Pharmacology Seminar Room – Sherrington Building (1st floor). Host: Professor Chris Goldring

@livuni-ismib.bsky.social
September 1, 2025 at 2:43 PM
livuni-ismib.bsky.social
BLOG | School of Biosciences graduate Jemma Clarke tells us about her summer of science last year on a research placement with Professor Daniel Rigden

➡️ bit.ly/4mMbftK

#TeamLivUni
A blog title card that reads 'Using machine learning to understand the mechanisms of cancer' in white text against a teal background surrounded by a white box. Pictured to the right is Jemma Clarke holding her graduation certificate in front of large letters spelling 'UOL'.
August 19, 2025 at 1:12 PM