Michelle Linterman
@linterman.bsky.social
Programme Leader @malaghan.bsky.social & Associate Group Leader @babrahaminst.bsky.social, working on germinal centres, vaccines and tertiary lymphoid structures.
Great to have this out, and such a pleasure to work together. @smguillaume.bsky.social @cristianbeccaria.bsky.social @iannaconelab.bsky.social
So happy to share that our review in #ImmunolRev is finally out! 😃 We discuss how the immune system builds specialized TLSs across organs and conditions. Huge thanks to @StephanGuillaume, @iannaconelab.bsky.social & @linterman.bsky.social for this collaboration!
dx.doi.org/10.1111/imr.70063
dx.doi.org/10.1111/imr.70063
Tertiary Lymphoid Structures Across Organs: Context, Composition, and Clinical Levers
Tertiary lymphoid structures (TLSs) arise in non-lymphoid tissues in response to persistent antigen stimulation and chronic inflammation. Spanning organs from lung and liver to meninges, skin, and be...
dx.doi.org
September 25, 2025 at 7:53 PM
Great to have this out, and such a pleasure to work together. @smguillaume.bsky.social @cristianbeccaria.bsky.social @iannaconelab.bsky.social
Reposted by Michelle Linterman
Save the date! Keystone Stromal Immunology meeting, Feb 2-5, 2026 #KSStromal26
1. Scholarships/Short Talk Abstracts: October 7
2. Early Registration: December 3 (Save $200!)
3. Poster Abstracts: January 12, 2026 (11:59 MST)
Please share! And reach out if you have any questions.
Can't wait!
1. Scholarships/Short Talk Abstracts: October 7
2. Early Registration: December 3 (Save $200!)
3. Poster Abstracts: January 12, 2026 (11:59 MST)
Please share! And reach out if you have any questions.
Can't wait!
August 4, 2025 at 10:52 PM
Save the date! Keystone Stromal Immunology meeting, Feb 2-5, 2026 #KSStromal26
1. Scholarships/Short Talk Abstracts: October 7
2. Early Registration: December 3 (Save $200!)
3. Poster Abstracts: January 12, 2026 (11:59 MST)
Please share! And reach out if you have any questions.
Can't wait!
1. Scholarships/Short Talk Abstracts: October 7
2. Early Registration: December 3 (Save $200!)
3. Poster Abstracts: January 12, 2026 (11:59 MST)
Please share! And reach out if you have any questions.
Can't wait!
It was great to be back at the @babrahaminst.bsky.social this week to spend time with the team talking about our science, and even managed a (very well timed) paper celebration! Amazing Tfh/GC themed brownie from Jess James.
September 5, 2025 at 7:14 PM
It was great to be back at the @babrahaminst.bsky.social this week to spend time with the team talking about our science, and even managed a (very well timed) paper celebration! Amazing Tfh/GC themed brownie from Jess James.
Thank you @immunologyking.bsky.social & @maurogaya.bsky.social for organising the #EMBObarrierTissues meeting in Basel this week. Great science, great people, great atmosphere ❤️
August 30, 2025 at 9:42 AM
Thank you @immunologyking.bsky.social & @maurogaya.bsky.social for organising the #EMBObarrierTissues meeting in Basel this week. Great science, great people, great atmosphere ❤️
Thank you Diana! Credit to @smguillaume.bsky.social for leading this work. Lung B cells in ectopic germinal centers undergo affinity maturation | PNAS share.google/6zXPfzAaAcva...
August 28, 2025 at 4:01 PM
Thank you Diana! Credit to @smguillaume.bsky.social for leading this work. Lung B cells in ectopic germinal centers undergo affinity maturation | PNAS share.google/6zXPfzAaAcva...
Beautiful talk from @mahimaswamy.bsky.social at #EMBObarrierTissues. Conserved developmental rewiring of the TCR signalosome drives tolerance in innate-like lymphocytes | bioRxiv share.google/UroEHTZJI7tk...
Conserved developmental rewiring of the TCR signalosome drives tolerance in innate-like lymphocytes
Natural intraepithelial T lymphocytes (T-IELs) are innate-like, intestine-resident T cells essential for gut homeostasis. These cells express self-reactive T cell antigen receptors (TCRs) due to thymi...
share.google
August 27, 2025 at 10:11 AM
Beautiful talk from @mahimaswamy.bsky.social at #EMBObarrierTissues. Conserved developmental rewiring of the TCR signalosome drives tolerance in innate-like lymphocytes | bioRxiv share.google/UroEHTZJI7tk...
Fantastic @embo.org young investigator lecture on lung B cell responses from @maurogaya.bsky.social #EMBObarrierTissues
August 27, 2025 at 9:48 AM
Fantastic @embo.org young investigator lecture on lung B cell responses from @maurogaya.bsky.social #EMBObarrierTissues
Thank you Cris 🙏
Credit to Alyssa Silva Cayetano and Theresa Pankhurst for leading these research projects
Credit to Alyssa Silva Cayetano and Theresa Pankhurst for leading these research projects
Amazing talk by Michelle @linterman.bsky.social at @iuis-online.bsky.social 2025 on ageing and immune responses to vaccines, shedding light on how understanding these mechanisms can guide the development of better immunization strategies
August 22, 2025 at 11:34 AM
Thank you Cris 🙏
Credit to Alyssa Silva Cayetano and Theresa Pankhurst for leading these research projects
Credit to Alyssa Silva Cayetano and Theresa Pankhurst for leading these research projects
Absolutely fantastic to have @labliston.bsky.social visiting the @malaghan.bsky.social this week. Beautiful talk on harnessing the power of Tregs to promote tissue repair, as well as many scientific discussions, an award ceremony at @nzparliament.bsky.social and multiple runs up our hills!
August 16, 2025 at 7:17 AM
Absolutely fantastic to have @labliston.bsky.social visiting the @malaghan.bsky.social this week. Beautiful talk on harnessing the power of Tregs to promote tissue repair, as well as many scientific discussions, an award ceremony at @nzparliament.bsky.social and multiple runs up our hills!
A pleasure to have you in Aotearoa New Zealand to celebrate science!
Great event at @nzparliament.bsky.social for Medicines New Zealand, with lots of exciting innovations in medical research on display. Thanks to @linterman.bsky.social from @malaghan.bsky.social for the invite!
August 15, 2025 at 7:45 AM
A pleasure to have you in Aotearoa New Zealand to celebrate science!
Fantastic to have Johanne Jacobsen at @malaghan.bsky.social this week presenting her beautiful work on germinal centre T cells, in all their complexity.
July 11, 2025 at 9:31 AM
Fantastic to have Johanne Jacobsen at @malaghan.bsky.social this week presenting her beautiful work on germinal centre T cells, in all their complexity.
Finally, after moving halfway across the world to beautiful Aotearoa New Zealand, our (Italian) espresso machine has arrived. Even better that we can get tasty beans from Acme who also make a special @malaghan.bsky.social blend that supports our research ❤️ lnkd.in/gbWi6RuW
July 4, 2025 at 9:01 AM
Finally, after moving halfway across the world to beautiful Aotearoa New Zealand, our (Italian) espresso machine has arrived. Even better that we can get tasty beans from Acme who also make a special @malaghan.bsky.social blend that supports our research ❤️ lnkd.in/gbWi6RuW
Great to have the @jimmunol.bsky.social special collection, “Aging's impact on the immune system” out. academic.oup.com/jimmunol/pag...
Aging's impact on the immune system
Description
This 2025 collection of The Journal of Immunology features a special collection of articles curated by guest editor Patricia Gearhart. The collecti
academic.oup.com
June 6, 2025 at 10:06 PM
Great to have the @jimmunol.bsky.social special collection, “Aging's impact on the immune system” out. academic.oup.com/jimmunol/pag...
Reposted by Michelle Linterman
Highlights of 2024: unleashing the power of NK cells—cancer's worst nightmare
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
June 5, 2025 at 2:36 AM
Highlights of 2024: unleashing the power of NK cells—cancer's worst nightmare
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Michelle Linterman
🚨🦠🔬 Last month to register to the EMBO workshop on Adaptive Immunity in Barrier Tissues.
📍 Where: Basel, Switzerland
📅 When: 26th–29th August 2025
📝 Registration deadline: 30th May 2025
Childcare support & travel grants from @embo.org and @efis-immunology.bsky.social
#EMBOBarrierTissues
📍 Where: Basel, Switzerland
📅 When: 26th–29th August 2025
📝 Registration deadline: 30th May 2025
Childcare support & travel grants from @embo.org and @efis-immunology.bsky.social
#EMBOBarrierTissues
Adaptive immunity in barrier tissues
Immune responses lie at the heart of almost every aspect of human health, including host responses to infection, autoimmunity, cancer, metabolism and aging. While adaptive immune responses by B and T…
meetings.embo.org
April 30, 2025 at 3:04 PM
🚨🦠🔬 Last month to register to the EMBO workshop on Adaptive Immunity in Barrier Tissues.
📍 Where: Basel, Switzerland
📅 When: 26th–29th August 2025
📝 Registration deadline: 30th May 2025
Childcare support & travel grants from @embo.org and @efis-immunology.bsky.social
#EMBOBarrierTissues
📍 Where: Basel, Switzerland
📅 When: 26th–29th August 2025
📝 Registration deadline: 30th May 2025
Childcare support & travel grants from @embo.org and @efis-immunology.bsky.social
#EMBOBarrierTissues
Our @immunolcellbiol.bsky.social "Highlights of 2024: Germinal Centers" is now out. Led by Theresa Pankhurst, we discuss some (there's never enough space for all!) neat germinal centre papers that were published in 2024, and whose findings are moving the field forward. doi.org/10.1111/imcb...
<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library
In this article for the Highlights of 2024 series, we review the latest advances in the biology of the germinal center response. These discoveries provide key insights into germinal center function a...
doi.org
May 22, 2025 at 12:13 AM
Our @immunolcellbiol.bsky.social "Highlights of 2024: Germinal Centers" is now out. Led by Theresa Pankhurst, we discuss some (there's never enough space for all!) neat germinal centre papers that were published in 2024, and whose findings are moving the field forward. doi.org/10.1111/imcb...
Can't wait! I'm really looking forward to this meeting, so many amazing talks. Thanks @maurogaya.bsky.social @immunologyking.bsky.social @embo.org for organising ❤️ #EMBOBarrierTissues
Dr. Michelle Linterman from the Malaghan/Babraham Institutes 🇳🇿🇬🇧 will be presenting her work on "Function and maintenance of lung germinal centres". Check her recent study on how lung B cells undergo affinity maturation:
pubmed.ncbi.nlm.nih.gov/40168127/
@linterman.bsky.social
#EMBOBarrierTissues
pubmed.ncbi.nlm.nih.gov/40168127/
@linterman.bsky.social
#EMBOBarrierTissues
May 16, 2025 at 7:11 AM
Can't wait! I'm really looking forward to this meeting, so many amazing talks. Thanks @maurogaya.bsky.social @immunologyking.bsky.social @embo.org for organising ❤️ #EMBOBarrierTissues
Neat @pnas.org paper from @angelettilab.bsky.social & @matsbemark.bsky.social on ectopic germinal centres in the nasal turbinates of mice and humans. doi.org/10.1073/pnas...
Ectopic germinal centers in the nasal turbinates contribute to B cell immunity to intranasal viral infection and vaccination | PNAS
The nasal mucosa is the first immunologically active site that respiratory viruses
encounter and establishing immunity at the initial point of path...
doi.org
April 27, 2025 at 11:14 PM
Neat @pnas.org paper from @angelettilab.bsky.social & @matsbemark.bsky.social on ectopic germinal centres in the nasal turbinates of mice and humans. doi.org/10.1073/pnas...
Thank you for the @thelisterinstitute.bsky.social support for this project! We couldn't have done it without you.
A new paper from #ListerFellow @linterman.bsky.social and colleagues explores the role of tertiary lymphoid structures (TLS) in #bcell immune response. @pnas.org doi.org/10.1073/pnas...
Lung B cells in ectopic germinal centers undergo affinity maturation | PNAS
The lungs are constantly exposed to the external environment and a myriad of antigenic
challenges within the air. Chronic exposure to allergens and...
doi.org
April 8, 2025 at 8:45 PM
Thank you for the @thelisterinstitute.bsky.social support for this project! We couldn't have done it without you.
Reposted by Michelle Linterman
Lung B cells in ectopic germinal centers undergo affinity maturation
www.pnas.org/doi/10.1073/...
@linterman.bsky.social
@smguillaume.bsky.social
@wsfoster.bsky.social
@sanmarti92.bsky.social
@emae-watson.bsky.social
www.pnas.org/doi/10.1073/...
@linterman.bsky.social
@smguillaume.bsky.social
@wsfoster.bsky.social
@sanmarti92.bsky.social
@emae-watson.bsky.social
April 3, 2025 at 8:28 PM
Lung B cells in ectopic germinal centers undergo affinity maturation
www.pnas.org/doi/10.1073/...
@linterman.bsky.social
@smguillaume.bsky.social
@wsfoster.bsky.social
@sanmarti92.bsky.social
@emae-watson.bsky.social
www.pnas.org/doi/10.1073/...
@linterman.bsky.social
@smguillaume.bsky.social
@wsfoster.bsky.social
@sanmarti92.bsky.social
@emae-watson.bsky.social
Great to have our paper out in @pnas.org showing that lung B cells in ectopic germinal centers undergo affinity maturation.
@smguillaume.bsky.social @wsfoster.bsky.social @sanmarti92.bsky.social @emae-watson.bsky.social Silvia Innocentin, Grant Kennedy & Alice Denton. doi.org/10.1073/pnas...
@smguillaume.bsky.social @wsfoster.bsky.social @sanmarti92.bsky.social @emae-watson.bsky.social Silvia Innocentin, Grant Kennedy & Alice Denton. doi.org/10.1073/pnas...
Lung B cells in ectopic germinal centers undergo affinity maturation | PNAS
The lungs are constantly exposed to the external environment and a myriad of antigenic
challenges within the air. Chronic exposure to allergens and...
doi.org
April 3, 2025 at 3:03 AM
Great to have our paper out in @pnas.org showing that lung B cells in ectopic germinal centers undergo affinity maturation.
@smguillaume.bsky.social @wsfoster.bsky.social @sanmarti92.bsky.social @emae-watson.bsky.social Silvia Innocentin, Grant Kennedy & Alice Denton. doi.org/10.1073/pnas...
@smguillaume.bsky.social @wsfoster.bsky.social @sanmarti92.bsky.social @emae-watson.bsky.social Silvia Innocentin, Grant Kennedy & Alice Denton. doi.org/10.1073/pnas...
Thanks to @zanivanlab.bsky.social , Max Mazzone and the Forbeck Research Foundation for a fantastic Forum on Harnessing stroma immune interactions for anti-cancer therapy. I learnt a huge amount from the participants and all the discussion.
www.forbeckforums.org/forums/harne...
www.forbeckforums.org/forums/harne...
Harnessing stroma-immune interactions for anti-cancer therapy | Forbeck Forums
www.forbeckforums.org
March 30, 2025 at 7:56 PM
Thanks to @zanivanlab.bsky.social , Max Mazzone and the Forbeck Research Foundation for a fantastic Forum on Harnessing stroma immune interactions for anti-cancer therapy. I learnt a huge amount from the participants and all the discussion.
www.forbeckforums.org/forums/harne...
www.forbeckforums.org/forums/harne...
Great to have our latest review "The cellular factors that impair the germinal center in advanced age" out @jimmunol.bsky.social.
Work led by @wsfoster.bsky.social and Edith Marcial-Juárez. With @sanmarti92.bsky.social creating the beautiful GC images in figure 2.
doi.org/10.1093/jimm...
Work led by @wsfoster.bsky.social and Edith Marcial-Juárez. With @sanmarti92.bsky.social creating the beautiful GC images in figure 2.
doi.org/10.1093/jimm...
March 17, 2025 at 9:42 PM
Great to have our latest review "The cellular factors that impair the germinal center in advanced age" out @jimmunol.bsky.social.
Work led by @wsfoster.bsky.social and Edith Marcial-Juárez. With @sanmarti92.bsky.social creating the beautiful GC images in figure 2.
doi.org/10.1093/jimm...
Work led by @wsfoster.bsky.social and Edith Marcial-Juárez. With @sanmarti92.bsky.social creating the beautiful GC images in figure 2.
doi.org/10.1093/jimm...
Thanks for highlighting our work. Credit goes to @wsfoster.bsky.social and Edith Marcial-Juárez for bringing this together
March 13, 2025 at 5:16 AM
Thanks for highlighting our work. Credit goes to @wsfoster.bsky.social and Edith Marcial-Juárez for bringing this together
Thanks for the shout out. Credit to William Foster and Edith Marcial-Juárez for leading on this review.
Terrific #ImmunoAgeing Review @jimmunol.bsky.social from
@linterman.bsky.social & friends @babrahaminst.bsky.social
"Thanks for the #Memory"
#Bcells #GerminalCenter #Immunity
#Infection #Vaccination #Antibodies
@linterman.bsky.social & friends @babrahaminst.bsky.social
"Thanks for the #Memory"
#Bcells #GerminalCenter #Immunity
#Infection #Vaccination #Antibodies
The cellular factors that impair the germinal center in advanced age
Abstract. Long-lasting immunological memory is a core feature of the adaptive immune system that allows an organism to have a potent recall response to for
academic.oup.com
March 11, 2025 at 7:49 AM
Thanks for the shout out. Credit to William Foster and Edith Marcial-Juárez for leading on this review.