Agostino Leone
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leoneago.bsky.social
Agostino Leone
@leoneago.bsky.social
🇮🇹 #firstgen marine biologist and molecular ecologist at the University of Palermo. Former IFREMER, AZTI-tecnalia and University of Bologna researcher.
#fish #elasmobranchs #genomics #eDNA #molecularecology #evolution #MPAs
🌊🦈🐟🦑🧬🧪💻📊☕ coffeeholic
Own Views
Reposted by Agostino Leone
#PopGen New preprint of the team on the discovery of a very high rate of polymorphic duplication in a marine bivalve.

Imagine looking at the distribution of the allelic coverage fraction at heterozygous calls in an indivdual and getting this distribution 👇 😱😱😱
July 1, 2025 at 12:47 PM
Reposted by Agostino Leone
#JFB: Prolonged use of freshwater habitats by the European sea bass revealed by otolith chemical analysis doi.org/10.1111/jfb.70069 #FishSci
doi.org
September 11, 2025 at 3:13 PM
If it had been published a few years ago, my academic life would have been far less difficult 🤣🤣🤣🤟
August 18, 2025 at 4:17 PM
Reposted by Agostino Leone
New #popgen tools I found that use a likelihood method to mitigate small sample size problem when calculating IBD that can be great for #consgen purposes: www.nature.com/articles/s41...

This has Windows implementation as well as Linux and Mac! Let me know if anyone has tried this :D
EMIBD9: Estimating 9 condensed IBD coefficients, inbreeding and relatedness from marker genotypes - Heredity
Heredity - EMIBD9: Estimating 9 condensed IBD coefficients, inbreeding and relatedness from marker genotypes
www.nature.com
April 25, 2025 at 10:07 AM
Long runs of homozygosity are reliable genomic markers of inbreeding depression: Trends in Ecology & Evolution www.cell.com/trends/ecolo...
Long runs of homozygosity are reliable genomic markers of inbreeding depression
A long-standing goal in ecological, evolutionary, and conservation genetics is to identify genomic correlates of fitness and inbreeding depression. Over the past several years, a growing body of theor...
www.cell.com
August 4, 2025 at 1:47 PM
Happy to share our new review, led by Chrystelle Delord, Natacha Nikolic, @sofarndhnd.bsky.social and other people not on bluesky, about the Ne estimation in large marine populations, plus a simulation framework onlinelibrary.wiley.com/doi/10.1111/...
#PopGen #PopulationGenomics #PopulationGenetics
Effective Population Size Estimation in Large Marine Populations: Considering Current Challenges and Opportunities When Simulating Large Data Sets With High‐Density Genomic Information
Next-generation-sequencing has broadened perspectives regarding the estimation of the effective population size (Ne) by providing high-density genomic information. These technologies have expanded da...
onlinelibrary.wiley.com
August 4, 2025 at 1:33 PM
Reposted by Agostino Leone
One more tool available to analyze the spatial structure of clade distribution. Always welcome!
📖Published📖

Matthew Kling presents phylospatial, a new R package that fully supports probability, abundance, and binary community data across a range of spatial phylogenetic diversity (PD) analyses 🌎 🧪 Check the article out here 👇

buff.ly/onf4BV6
May 26, 2025 at 3:46 PM
Reposted by Agostino Leone
Pangenomes are not just for humans 👨‍👩‍👧‍👧, livestock 🐮🐷, and crops 🌾🌱 --- highlight yours by adding it below! #biodiversity #genomics
onlinelibrary.wiley.com/doi/abs/10.1...
Pan‐genome analysis highlights the role of structural variation in the evolution and environmental adaptation of Asian honeybees
The Asian honeybee, Apis cerana, is an ecologically and economically important pollinator. Mapping its genetic variation is key to understanding population-level health, histories and potential capac...
onlinelibrary.wiley.com
May 25, 2025 at 1:02 PM
Reposted by Agostino Leone
It has been since its first use in 1950, so confusing!
Here is our attempt to clarify and organize this concept in population genetics: www.nature.com/articles/s41...
Apologies for this sort of self-promo but it was born from this exact feeling
Genetic load: genomic estimates and applications in non-model animals - Nature Reviews Genetics
The reduction in individual and mean population fitness induced by novel deleterious genetic variation is known as the genetic load. Bertorelle et al. review the definition of the genetic load and its...
www.nature.com
May 27, 2025 at 11:59 AM
Reposted by Agostino Leone
Check out our new blog post, 'Tracking animals with particles'! Edward Lavender talks about the use of particle algorithms for movement modelling in passive acoustic telemetry systems 🐟 🌎 🧪 👇

buff.ly/8AJpP7I
May 20, 2025 at 12:50 PM
Reposted by Agostino Leone
How Microplastics Are Threatening Shark Reproduction
How Microplastics Are Threatening Shark Reproduction
Microplastics are accumulating in sharks’ gonads and GI tracts, disrupting reproduction and threatening population recovery.
www.forbes.com
May 4, 2025 at 2:52 PM
Reposted by Agostino Leone
Forbes column from #shark researcher @melissacmarquez.bsky.social: a study of spadenose sharks on #India 's West coast finds microplastics "...in every water sample collected, 97.9% of GI tract samples and 95% of gonadal tissues."

Click through for discussion about how this may impact sharks
May 4, 2025 at 3:12 PM
Reposted by Agostino Leone
Published version of our spatial simulations paper led by Jiseon Min and Elsie Chevy is up 🔐! This was such a fun paper to be a part of and a valuable resource to folks thinking population simulations of all kinds, even non-genetic ones! onlinelibrary.wiley.com/doi/epdf/10....
Population Genetics Meets Ecology: A Guide to Individual‐Based Simulations in Continuous Landscapes
onlinelibrary.wiley.com
April 15, 2025 at 12:38 PM
Reposted by Agostino Leone
2-years #postdoc opportunity in #Brest #France to study #marine grey (anthropogenic) #connectivity #MarCo #GreyCo with Langrangian simulations, with the ultimate aim of integrating them with population genetics #PopGen data. #MarEvol #MarineEcology #Research
www.talentdetection.com/ifremer/offr...
Annonce Emploi Postdoctoral Researcher in marine connectivity modelling (M/F) à Plouzané en CDD par Ifremer
Ifremer recrute en ce moment un(e) Postdoctoral Researcher in marine connectivity modelling (M/F) à Plouzané en CDD. ⭐️ Postulez Maintenant en ligne, c'est Simple et Rapide !
www.talentdetection.com
April 8, 2025 at 11:40 AM
Reposted by Agostino Leone
Like many of you, I have very strong, negative opinions about the current state of affairs, and I discuss those grievances with people daily. On this platform, I would like to share a very useful data analysis workflow that I've found in the effort of better transparency and reproducibility🧵:
February 26, 2025 at 3:32 PM
Reposted by Agostino Leone
Admixture (rescue?) + killer whales + Australia + @andrewfoote.bsky.social et al. = 🤩 #PopGen #MarEvol
The 2nd publication from @bellareeves.bsky.social PhD thesis finds a genetic rescue effect from admixture between distinct killer whale lineages. Likely the cause of high genetic diversity in regions with low killer whale density. Open access in Mol Ecol: onlinelibrary.wiley.com/doi/epdf/10....
March 1, 2025 at 7:47 AM
Reposted by Agostino Leone
✨We are hiring!✨🧪🏛️🧬
The @nhmdk.bsky.social at the University of Copenhagen is seeking a permanent, full-time Molecular Biology Lab Manager to help us establish and run our National Facility for #Museomics in the heart of one of Europe's most beautiful cities!
Please reskeet!
Full-time Molecular Biology Lab Manager at Natural History Museum Denmark
Natural History Museum Denmark, Faculty of Science, the University of Copenhagen is looking for a full-time Molecular Biology Lab Manager, to start 1st June 202
candidate.hr-manager.net
February 10, 2025 at 7:43 PM
Reposted by Agostino Leone
Registration for Evolution 2025 is now open! Come join us virtually from May 29-30, and/or in-person in Athens, GA from June 20-24.

@sse-evolution.bsky.social @systbiol.bsky.social @asn-amnat.bsky.social #Evol2025

www.evolutionmeetings.org/registration...
Evolution 2025 Registration
Evolution 2025 - the joint conference of the SSE, ASN, and SSB
www.evolutionmeetings.org
February 10, 2025 at 7:29 PM
Reposted by Agostino Leone
‼️These #PSMC #peaks are #artifacts‼️

Seen #PSMC results like this🤔?
They are caused by ill-set parameters, #very #common, and #easy #to #solve!

For details see 🧵& OA paper @currentbiology.bsky.social
🙂🐢🧬🎉!

cell.com/current-biol...
Avoidable false PSMC population size peaks occur across numerous studies
Hilgers et al. detect and solve a common artifact in PSMC and related methods for historical population size inference. Analyses of real and simulated genomes show that ill-set default parameters fals...
cell.com
February 7, 2025 at 8:14 AM