Leah Ziolkowski
@leahziolkowski.bsky.social
6th year PhD candidate at UChicago in the Macleod Lab | NCI F31 Fellow | Research interests: pancreatic cancer tumorigenesis & acinar cell metabolism
Thrilled to be back in Boston for the AACR conference on Pancreatic Cancer and for the opportunity to present my work as an AACR Scholar in Training this evening! Find me at poster A007- I'd love to chat about all I've been working on!
#AACRpan25
@theaacr.bsky.social
#AACRpan25
@theaacr.bsky.social
September 29, 2025 at 2:12 PM
Thrilled to be back in Boston for the AACR conference on Pancreatic Cancer and for the opportunity to present my work as an AACR Scholar in Training this evening! Find me at poster A007- I'd love to chat about all I've been working on!
#AACRpan25
@theaacr.bsky.social
#AACRpan25
@theaacr.bsky.social
Reposted by Leah Ziolkowski
Super excited to share our new preprint from @cssheehan.bsky.social on how the tumor microenvironment causes drug resistance in pancreatic cancer: www.biorxiv.org/content/10.1...
Tumor nutrient stress gives rise to a drug tolerant cell state in pancreatic cancer
Cytotoxic chemotherapy remains the standard-of-care treatment for patients with pancreatic ductal adenocarcinoma (PDAC). However, chemotherapy only has modest effects at improving patient survival due...
www.biorxiv.org
September 9, 2025 at 9:38 PM
Super excited to share our new preprint from @cssheehan.bsky.social on how the tumor microenvironment causes drug resistance in pancreatic cancer: www.biorxiv.org/content/10.1...
Reposted by Leah Ziolkowski
Super great to work with James LaBelle’s lab on this project! And thanks to everyone involved in the study: Kay Macleod, @cjhphd.bsky.social, Alica Beutel,
@leahziolkowski.bsky.social, Mumina Sadullozoda, @patrickjonker.bsky.social, Darby Agovino, Grace Croley, @guillaumecognet.bsky.social.
@leahziolkowski.bsky.social, Mumina Sadullozoda, @patrickjonker.bsky.social, Darby Agovino, Grace Croley, @guillaumecognet.bsky.social.
September 9, 2025 at 9:38 PM
Super great to work with James LaBelle’s lab on this project! And thanks to everyone involved in the study: Kay Macleod, @cjhphd.bsky.social, Alica Beutel,
@leahziolkowski.bsky.social, Mumina Sadullozoda, @patrickjonker.bsky.social, Darby Agovino, Grace Croley, @guillaumecognet.bsky.social.
@leahziolkowski.bsky.social, Mumina Sadullozoda, @patrickjonker.bsky.social, Darby Agovino, Grace Croley, @guillaumecognet.bsky.social.
Feeling incredibly grateful this week! Honored to receive the AACR Scholar-in-Training Award for the upcoming conference on Pancreatic Cancer in Boston & thrilled to get the NoA for a second year of F31 funding to continue my research on PDAC tumorigenesis in the Macleod Lab!
August 18, 2025 at 8:51 PM
Feeling incredibly grateful this week! Honored to receive the AACR Scholar-in-Training Award for the upcoming conference on Pancreatic Cancer in Boston & thrilled to get the NoA for a second year of F31 funding to continue my research on PDAC tumorigenesis in the Macleod Lab!
Tomorrow morning at AACR, I will be presenting my poster on the Integrated Stress Response in PDAC tumorigenesis! Would love to chat about what I've been working on in the Macleod Lab- find me at Section 11 (Metabolism and Signaling), Board 19 from 9am to noon!
April 30, 2025 at 2:34 AM
Tomorrow morning at AACR, I will be presenting my poster on the Integrated Stress Response in PDAC tumorigenesis! Would love to chat about what I've been working on in the Macleod Lab- find me at Section 11 (Metabolism and Signaling), Board 19 from 9am to noon!
Reposted by Leah Ziolkowski
Excited to share new report from collaborative work from @delgoffelab.bsky.social and @patrickjonker.bsky.social from our team on a novel metabolic suppressor of T cell function in tumors! rdcu.be/eiyIa 1/
Tumour interstitial fluid-enriched phosphoethanolamine suppresses T cell function
Nature Cell Biology - Wang, Wilfahrt and colleagues show that phosphoethanolamine, a phospholipid intermediate, is enriched in tumour interstitial fluid and induces T cell dysfunction, in part by...
rdcu.be
April 21, 2025 at 2:24 PM
Excited to share new report from collaborative work from @delgoffelab.bsky.social and @patrickjonker.bsky.social from our team on a novel metabolic suppressor of T cell function in tumors! rdcu.be/eiyIa 1/
Reposted by Leah Ziolkowski
🔥 Hot off the press: Researchers at the University of Chicago, in collaboration with the University of Pittsburgh, have published a groundbreaking study in @NatureCellBio demonstrating how the accumulation of a tumor metabolite impairs T cell function in the tumor microenvironment.
ow.ly/vxWI50VEJVm
ow.ly/vxWI50VEJVm
Tumor byproduct blocks immune cells from fighting cancer - UChicago Medicine
Researchers from the University of Chicago and the University of Pittsburgh have identified a novel oncometabolite that accumulates in tumors and impairs immune cells’ ability to fight cancer.
ow.ly
April 21, 2025 at 2:43 PM
🔥 Hot off the press: Researchers at the University of Chicago, in collaboration with the University of Pittsburgh, have published a groundbreaking study in @NatureCellBio demonstrating how the accumulation of a tumor metabolite impairs T cell function in the tumor microenvironment.
ow.ly/vxWI50VEJVm
ow.ly/vxWI50VEJVm
Reposted by Leah Ziolkowski
Hi #metabolism #pancreaticcancer #lipidtime twitter! Excited to share @patrickjonker.bsky.social work on how the microenvironment limits the metabolic capacity of pancreatic cancers (PDAC), which sensitizes these tumors to dietary interventions. 1/17
Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis https://www.biorxiv.org/content/10.1101/2025.03.10.642426v1
March 14, 2025 at 9:26 PM
Hi #metabolism #pancreaticcancer #lipidtime twitter! Excited to share @patrickjonker.bsky.social work on how the microenvironment limits the metabolic capacity of pancreatic cancers (PDAC), which sensitizes these tumors to dietary interventions. 1/17
Reposted by Leah Ziolkowski
I’m Standing Up for Science today in Chicago against the shameful, destructive, and illegal funding cuts by President Trump and Elon Musk. Researchers at National Institutes of Health find breakthrough treatments and cures. They deserve support—not attacks.
March 7, 2025 at 7:09 PM
I’m Standing Up for Science today in Chicago against the shameful, destructive, and illegal funding cuts by President Trump and Elon Musk. Researchers at National Institutes of Health find breakthrough treatments and cures. They deserve support—not attacks.
For anyone in the area, Chicago is gathering at 12PM at the Federal Plaza on March 7th to #StandUpForScience2025!
March 6, 2025 at 2:45 PM
For anyone in the area, Chicago is gathering at 12PM at the Federal Plaza on March 7th to #StandUpForScience2025!