Dr. Lydia Andreyevna Krasilnikova, MEng, PhD
@lakrasil.bsky.social
✨ infectious disease bioinformatician at Massachusetts DPH ✨
✨ writer ✨ artist ✨
✨ previously Sabeti Lab, Broad Institute, Harvard OEB, MIT 6-7/18/lots of 21W, Penn State ✨
✨ https://lakrasilnikova.home.blog ✨
✨ opinions my own ✨
✨ writer ✨ artist ✨
✨ previously Sabeti Lab, Broad Institute, Harvard OEB, MIT 6-7/18/lots of 21W, Penn State ✨
✨ https://lakrasilnikova.home.blog ✨
✨ opinions my own ✨
Reposted by Dr. Lydia Andreyevna Krasilnikova, MEng, PhD
I’m thrilled to share our latest preprint! We analyzed >130,000 SARS-CoV-2 genomes from MA to investigate complex transmission dynamics—from statewide patterns, within specific facilities, and at the individual level 🦠🧬
Check out the preprint here ⬇️
www.medrxiv.org/content/10.1...
Check out the preprint here ⬇️
www.medrxiv.org/content/10.1...
Geospatial and demographic patterns of SARS-CoV-2 spread in Massachusetts from over 130,000 genomes
Despite intensive study, gaps remain in our understanding of SARS-CoV-2 transmission patterns during the COVID-19 pandemic, in part due to limited contextual metadata accompanying most large genomic s...
www.medrxiv.org
April 9, 2025 at 7:11 PM
I’m thrilled to share our latest preprint! We analyzed >130,000 SARS-CoV-2 genomes from MA to investigate complex transmission dynamics—from statewide patterns, within specific facilities, and at the individual level 🦠🧬
Check out the preprint here ⬇️
www.medrxiv.org/content/10.1...
Check out the preprint here ⬇️
www.medrxiv.org/content/10.1...
Reposted by Dr. Lydia Andreyevna Krasilnikova, MEng, PhD
Measles requires 95% vaccination rates for herd immunity.
It has a 16.2% case fatality rate for unvaccinated children under 5 years and 24% for children under 9 months (who are unable to be vaccinated).
30% of the survivors experience severe complications like blindness, deafness, or encephalitis.
It has a 16.2% case fatality rate for unvaccinated children under 5 years and 24% for children under 9 months (who are unable to be vaccinated).
30% of the survivors experience severe complications like blindness, deafness, or encephalitis.
These are the vaccination rates of kindergartners by state. It takes 95% coverage of MMR vaccine to prevent measles outbreaks & most states are not achieving it. I fear that under the new administration rates will drop even further and we will start to see preventable illness, disability, and death
November 16, 2024 at 5:02 PM
Measles requires 95% vaccination rates for herd immunity.
It has a 16.2% case fatality rate for unvaccinated children under 5 years and 24% for children under 9 months (who are unable to be vaccinated).
30% of the survivors experience severe complications like blindness, deafness, or encephalitis.
It has a 16.2% case fatality rate for unvaccinated children under 5 years and 24% for children under 9 months (who are unable to be vaccinated).
30% of the survivors experience severe complications like blindness, deafness, or encephalitis.
Reposted by Dr. Lydia Andreyevna Krasilnikova, MEng, PhD
The measles outbreak in Texas is reminding me of the public letter Roald Dahl wrote about losing his daughter to measles in 1962, just before the vaccine was publicly available.
February 15, 2025 at 5:49 PM
The measles outbreak in Texas is reminding me of the public letter Roald Dahl wrote about losing his daughter to measles in 1962, just before the vaccine was publicly available.
Reposted by Dr. Lydia Andreyevna Krasilnikova, MEng, PhD
Reminder for the new semester that you can’t detect AI
Researchers secretly added AI-created papers to the exam pool: “We found that 94% of our AI submissions were undetected. The grades awarded to our AI submissions were on average half a grade boundary higher than that achieved by real students”
Researchers secretly added AI-created papers to the exam pool: “We found that 94% of our AI submissions were undetected. The grades awarded to our AI submissions were on average half a grade boundary higher than that achieved by real students”
January 6, 2025 at 2:04 PM
Reminder for the new semester that you can’t detect AI
Researchers secretly added AI-created papers to the exam pool: “We found that 94% of our AI submissions were undetected. The grades awarded to our AI submissions were on average half a grade boundary higher than that achieved by real students”
Researchers secretly added AI-created papers to the exam pool: “We found that 94% of our AI submissions were undetected. The grades awarded to our AI submissions were on average half a grade boundary higher than that achieved by real students”
Reposted by Dr. Lydia Andreyevna Krasilnikova, MEng, PhD
✨ Get a glimpse behind the scenes of this year’s holiday card! 🎥💫 Watch the magic come to life here: bit.ly/4gFdvjp
We hope it brings a little extra holiday cheer your way! 🎄💖
We hope it brings a little extra holiday cheer your way! 🎄💖
Behind the Scenes: Creating the Sabeti Lab's Holiday
Take a sneak peek into the magic behind the Sabeti Lab's holiday card! 🎄✨ A huge shoutout to our amazing holiday card crew for bringing this vision to life, and an extra-special thank you to Omayma Dalal for capturing the magic and creating this beautiful video. Happy Holidays from all of us!
bit.ly
December 19, 2024 at 5:52 PM
✨ Get a glimpse behind the scenes of this year’s holiday card! 🎥💫 Watch the magic come to life here: bit.ly/4gFdvjp
We hope it brings a little extra holiday cheer your way! 🎄💖
We hope it brings a little extra holiday cheer your way! 🎄💖
Reposted by Dr. Lydia Andreyevna Krasilnikova, MEng, PhD
What better way to kick off our Bluesky journey than with our annual holiday card? 🌟 Celebrate unity, humanity, and the milestones shaping a brighter future with us. Happy Holidays! 🎄✨ bit.ly/3Dsr6wk
December 19, 2024 at 5:39 PM
What better way to kick off our Bluesky journey than with our annual holiday card? 🌟 Celebrate unity, humanity, and the milestones shaping a brighter future with us. Happy Holidays! 🎄✨ bit.ly/3Dsr6wk
Losing flexibility has been by far the hardest thing about transitioning to a non-academic job. Proud to say that today, like I'm sure many adults, I woke up miserable, cried on the orange line, and then did my job anyway.
December 18, 2024 at 10:38 PM
Losing flexibility has been by far the hardest thing about transitioning to a non-academic job. Proud to say that today, like I'm sure many adults, I woke up miserable, cried on the orange line, and then did my job anyway.
Reposted by Dr. Lydia Andreyevna Krasilnikova, MEng, PhD
Are superspreaders always social butterflies? 🦋🦠
Our new study on temporal social contacts showed most people are highly connected only for brief periods. Crucially, this challenges the idea that respi outbreaks naturally subside once highly connected people becomes immune.
doi.org/10.1098/rsif...
Our new study on temporal social contacts showed most people are highly connected only for brief periods. Crucially, this challenges the idea that respi outbreaks naturally subside once highly connected people becomes immune.
doi.org/10.1098/rsif...
Temporal contact patterns and the implications for predicting superspreaders and planning of targeted outbreak control | Journal of The Royal Society Interface
Directly transmitted infectious diseases spread through social contacts that change over time, but outbreak models typically make simplifying assumptions about network structure and dynamics. To assess how common assumptions relate to real-world ...
doi.org
December 18, 2024 at 9:17 AM
Are superspreaders always social butterflies? 🦋🦠
Our new study on temporal social contacts showed most people are highly connected only for brief periods. Crucially, this challenges the idea that respi outbreaks naturally subside once highly connected people becomes immune.
doi.org/10.1098/rsif...
Our new study on temporal social contacts showed most people are highly connected only for brief periods. Crucially, this challenges the idea that respi outbreaks naturally subside once highly connected people becomes immune.
doi.org/10.1098/rsif...
Reposted by Dr. Lydia Andreyevna Krasilnikova, MEng, PhD
I'm seeing some (entirely justified) concern about the possibility of the US no longer having a polio vaccination program given the threat posed by the incoming administration and I feel like this is a really good opportunity to explain some things about polio to clarify what the risks are 🧵
December 15, 2024 at 11:22 PM
I'm seeing some (entirely justified) concern about the possibility of the US no longer having a polio vaccination program given the threat posed by the incoming administration and I feel like this is a really good opportunity to explain some things about polio to clarify what the risks are 🧵
I am now selling my heirloom pumpkins and squashes on Threadless! Come see what RedBubble deemed risqué enough to ban :p
(It's pumpkins. It's just pumpkins.)
lydiakayart.threadless.com/other-things...
(It's pumpkins. It's just pumpkins.)
lydiakayart.threadless.com/other-things...
November 28, 2024 at 2:07 AM
I am now selling my heirloom pumpkins and squashes on Threadless! Come see what RedBubble deemed risqué enough to ban :p
(It's pumpkins. It's just pumpkins.)
lydiakayart.threadless.com/other-things...
(It's pumpkins. It's just pumpkins.)
lydiakayart.threadless.com/other-things...
Reposted by Dr. Lydia Andreyevna Krasilnikova, MEng, PhD
I thought it might be worthwhile to do a quick primer on CDC.gov datasets and public data resources.
1. DATA.CDC.GOV (data.cdc.gov/browse)
Datasets from across the agency, in browsable, machine readable format (Socrata system). Other/older collections are on:
2. WONDER.CDC.GOV (wonder.cdc.gov)
1. DATA.CDC.GOV (data.cdc.gov/browse)
Datasets from across the agency, in browsable, machine readable format (Socrata system). Other/older collections are on:
2. WONDER.CDC.GOV (wonder.cdc.gov)
Data | Centers for Disease Control and Prevention
Data published by CDC public health programs to help save lives and protect people from health, safety, and security threats.
data.cdc.gov
November 20, 2024 at 7:29 PM
I thought it might be worthwhile to do a quick primer on CDC.gov datasets and public data resources.
1. DATA.CDC.GOV (data.cdc.gov/browse)
Datasets from across the agency, in browsable, machine readable format (Socrata system). Other/older collections are on:
2. WONDER.CDC.GOV (wonder.cdc.gov)
1. DATA.CDC.GOV (data.cdc.gov/browse)
Datasets from across the agency, in browsable, machine readable format (Socrata system). Other/older collections are on:
2. WONDER.CDC.GOV (wonder.cdc.gov)
My advice for/lessons from grad school, now as a thread ⬇️:
1. Go to grad school because you want to be in grad school. Don’t go to grad school if it’s something to endure in order to get to the next step. If the next step requires grad school then the next step is probably like grad school,
1\n
1. Go to grad school because you want to be in grad school. Don’t go to grad school if it’s something to endure in order to get to the next step. If the next step requires grad school then the next step is probably like grad school,
1\n
November 19, 2024 at 2:05 AM
My advice for/lessons from grad school, now as a thread ⬇️:
1. Go to grad school because you want to be in grad school. Don’t go to grad school if it’s something to endure in order to get to the next step. If the next step requires grad school then the next step is probably like grad school,
1\n
1. Go to grad school because you want to be in grad school. Don’t go to grad school if it’s something to endure in order to get to the next step. If the next step requires grad school then the next step is probably like grad school,
1\n
Reposted by Dr. Lydia Andreyevna Krasilnikova, MEng, PhD
If you do dengue virus sequencing +/- phylogenetic analysis, check out our new system for classifying lineages.
Led by Verity Hill, this was a large collaborative effort by dengue researchers from 14 countries.
Paper -> journals.plos.org/plosbiology/...
Website-> dengue-lineages.org
Led by Verity Hill, this was a large collaborative effort by dengue researchers from 14 countries.
Paper -> journals.plos.org/plosbiology/...
Website-> dengue-lineages.org
November 18, 2024 at 9:58 PM
If you do dengue virus sequencing +/- phylogenetic analysis, check out our new system for classifying lineages.
Led by Verity Hill, this was a large collaborative effort by dengue researchers from 14 countries.
Paper -> journals.plos.org/plosbiology/...
Website-> dengue-lineages.org
Led by Verity Hill, this was a large collaborative effort by dengue researchers from 14 countries.
Paper -> journals.plos.org/plosbiology/...
Website-> dengue-lineages.org
Reposted by Dr. Lydia Andreyevna Krasilnikova, MEng, PhD
To what extent is support for #publichealth falling because voters born prior to the 1940s, when 1 out of every 3 children died, are now mostly dead? A couple decades ago, a much larger share of the electorate had experienced the transformative impacts of #vaccination. @caulfieldtim.bsky.social
I updated the data in my article about the history of child mortality.
Without any large exceptions, every second child died — in Ancient Rome, in hunter-gatherer societies, in the pre-Columbian Americas, in Medieval Japan, in Imperial China, or the Renaissance.
ourworldindata.org/child-mortal...
Without any large exceptions, every second child died — in Ancient Rome, in hunter-gatherer societies, in the pre-Columbian Americas, in Medieval Japan, in Imperial China, or the Renaissance.
ourworldindata.org/child-mortal...
November 18, 2024 at 2:30 PM
To what extent is support for #publichealth falling because voters born prior to the 1940s, when 1 out of every 3 children died, are now mostly dead? A couple decades ago, a much larger share of the electorate had experienced the transformative impacts of #vaccination. @caulfieldtim.bsky.social
Welcome to my Bluesky page!
My name is Lydia. I am a bioinformatician who studies infectious disease. I also write and make art. Posts will be about all of the above.
Come talk with me!
My name is Lydia. I am a bioinformatician who studies infectious disease. I also write and make art. Posts will be about all of the above.
Come talk with me!
November 18, 2024 at 6:32 AM
Welcome to my Bluesky page!
My name is Lydia. I am a bioinformatician who studies infectious disease. I also write and make art. Posts will be about all of the above.
Come talk with me!
My name is Lydia. I am a bioinformatician who studies infectious disease. I also write and make art. Posts will be about all of the above.
Come talk with me!
My first blog post in a long while: lessons I learned in grad school, so that you don't have to.
lakrasilnikova.home.blog/2024/11/18/a...
lakrasilnikova.home.blog/2024/11/18/a...
November 18, 2024 at 6:24 AM
My first blog post in a long while: lessons I learned in grad school, so that you don't have to.
lakrasilnikova.home.blog/2024/11/18/a...
lakrasilnikova.home.blog/2024/11/18/a...