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labonachip.rsc.org
Lab on a Chip
@labonachip.rsc.org
310 followers 170 following 72 posts
The leading miniaturization journal for engineers, chemists, biologists, bioengineers, biomedical scientists, physicists, materials scientists, and more

Published by @rsc.org 🌐 Website: rsc.li/labonachip
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Reposted by Lab on a Chip
uoftdentlib.bsky.social
A new U of T #DentalFacultyPub! Microengineered diabetic wound-on-a-chip model for emulating chronic wound dynamics
Microengineered diabetic wound-on-a-chip model for emulating chronic wound dynamics - PubMed
Diabetic wounds, which affect 19-34% of individuals with diabetes mellitus, remain a serious complication due to their chronic, non-healing nature and high risk of limb amputation. Traditional 2D…
pubmed.ncbi.nlm.nih.gov
November 10, 2025 at 6:30 PM
labonachip.rsc.org
On the inside back cover of issue 22 of Lab on a Chip:
Trapping nanoscale particles via quasi-Scholte mode in acoustofluidics.
#OpenAccess from Feiyan Cai, Jianjian Wang, Yongqing Fu et al.
Read now: pubs.rsc.org/en/content/a...
Inside back cover of issue 22 of Lab on a Chip: Red particles moving across yellow and blue acoustic waves
November 6, 2025 at 1:22 PM
labonachip.rsc.org
On the back cover of issue 22 of Lab on a Chip:
Modular RCA-CRISPR/Cas12a amplification on a multi-volume SlipChip for ultrafast, single-copy quantification of circRNA and miRNA in ovarian cancer.
Jun Yang, Zaian Deng et al.
pubs.rsc.org/en/content/a...
Back cover of issue 22 of Lab on a Chip: Circular microfluidic chip for RNA analysis
November 6, 2025 at 1:08 PM
labonachip.rsc.org
On the inside front cover of issue 22 of Lab on a Chip:
High-throughput impedance monitoring in 3D tumor cultures: a multiplex, microfluidic-free platform for drug screening.
#OpenAccess from Gianni Ciofani, Attilio Marino, Kamil Ziaja et al
@iitalk.bsky.social pubs.rsc.org/en/content/a...
Inside front cover of issue 22 of Lab on a Chip: Image of impedence monitoring of tumour cells
November 5, 2025 at 2:42 PM
labonachip.rsc.org
On the front cover of issue 22 of Lab on a Chip:
A review of microfluidic approaches for carbon capture and storage research.
#OpenAccess from Myeongsub Kim et al.
pubs.rsc.org/en/content/a... #!divAbstract
front cover of issue 22 of Lab on a Chip: image shows carbon capture on microfluidic chips.
November 5, 2025 at 10:06 AM
Reposted by Lab on a Chip
lhinderling.bsky.social
microfabricated stamps, fresh off the printer :)
October 26, 2025 at 4:24 PM
Reposted by Lab on a Chip
mgh-id.bsky.social
pubs.rsc.org/en/content/a...
A luminescence-based point-of-care HIV viral load test for antiretroviral therapy monitoring
Effective monitoring of HIV treatment remains constrained by limited access to affordable, sensitive, and user-friendly viral load diagnostics, particularly in resource-limited settings. To address th...
pubs.rsc.org
October 29, 2025 at 2:06 PM
Reposted by Lab on a Chip
ertrunnell.bsky.social
The @darpa.mil funded study also demonstrated that human organ chips are a more clinically relevant model for preclinical testing of crRNA therapeutics’ efficacy and safety.

In @labonachip.rsc.org:
pubs.rsc.org/en/content/a...
Preclinical assessment of pan-influenza A virus CRISPR RNA therapeutics in a human lung alveolus chip
CRISPR technology offers an entirely new approach to therapeutic development because it can target specific nucleotide sequences with high specificity, however, preclinical animal models are not usefu...
pubs.rsc.org
October 29, 2025 at 11:41 PM
Reposted by Lab on a Chip
ertrunnell.bsky.social
To explore the use of CRISPR-Cas13 for developing influenza therapeutics, @wyssinstitute.bsky.social & @harvardmed.bsky.social scientists used a human lung chip infected with influenza A virus to evaluate the on-target and off-target effects of antiviral crRNA therapeutics. 🧪
A quote in black text reads: “[C]rRNA and gene target interactions are so specific and sensitive that the efficacy of antiviral crRNA therapeutics targeting human IAVs or human gene sequences cannot be assessed in animal models. ... Second, off-target effects and potential toxicities of crRNAs cannot be analyzed in animal models because humans and animals share different genomes, anatomy, immune systems, and physiology.” Below the quote is the citation in a yellow rectangle: Man et al. (2025) DOI: 10.1039/D5LC00156K. The design of the graphic includes an orange background with a yellow quotation mark to the top left, and part of a dark orange oval and a lighter orange oval with see-through lines running through it, perpendicular to one another, at the top right and bottom left.
October 29, 2025 at 11:41 PM
labonachip.rsc.org
On the inside back cover of issue 21 of Lab on a Chip:
Kappa(κ)Chip: a modular microfluidic device for analyte screening using parallelized assays and a multiple shear rate approach.
#OpenAccess from Jose A. Wippold et al.
Read now: pubs.rsc.org/en/content/a...
Inside back cover of issue 21 of Lab on a Chip
October 27, 2025 at 3:08 PM
labonachip.rsc.org
Engineering a diagnostic platform based on a spatially resolved electrochemiluminescence immunoassay for low-plex biomarker detection at point-of-care: mild traumatic brain injury and cardiac applications.
#OpenAccess from Marc E. Pfeifer et al.
Read now: pubs.rsc.org/en/content/a...
Back cover of issue 21 of Lab on a Chip: Analytes from a brain flowing into microfluidic chip.
October 27, 2025 at 1:21 PM
labonachip.rsc.org
On the inside front cover of issue 21 of Lab on a Chip:
In situ electrochemical measurement of alkaline phosphatase activity in engineered gut models using a porous membrane electrode device.
Kosuke Ino, Yoshinobu Utagawa et al.
pubs.rsc.org/en/content/a...
Inside front cover of issue 21 of Lab on a Chip: Yellow and pink cartoon characters anthropomorphising electrochemistry
October 27, 2025 at 9:43 AM
Reposted by Lab on a Chip
elishakrieg.bsky.social
Full article:
pubs.rsc.org/en/content/a...
Multiplexed detection of respiratory viral pathogens by isothermal amplification on an autonomously loaded chip at the point-of-care
Recent viral outbreaks have shown the need for reliable diagnostic platforms to rapidly detect various viral and bacterial pathogens at the point-of-care. Over the last decade, isothermal nucleic acid...
pubs.rsc.org
October 23, 2025 at 2:21 PM
labonachip.rsc.org
In our latest issue:
Myo-MOVES: a custom electrical stimulation system for functional studies of 3D bioengineered muscle
#OpenAccess from Juan M. Fernández-Costa, Javier Ramón-Azcón et al
@juanmafercos.bsky.social @ainoatejedera.bsky.social @ibecbarcelona.eu.
Read now: pubs.rsc.org/en/content/a...
Myo-MOVES: a custom electrical stimulation system for functional studies of 3D bioengineered muscle
Electrical pulse stimulation (EPS) is used to replicate motor neuron activation in muscle tissues, enabling in vitro studies of muscle contraction. However, both custom-built and commercial existing E...
pubs.rsc.org
October 22, 2025 at 11:26 AM
labonachip.rsc.org
On the front cover of issue 21 of Lab on a Chip:
Dynamic sub-wavelength microparticle patterning via phase-modulated pulsing coherent surface acoustic wave tweezers.
Yancheng Wang et al.
pubs.rsc.org/en/content/a...
Front cover of issue 21 of Lab on a Chip: Rendering of microfluidic chip with acoustic wave tweezers
October 22, 2025 at 9:45 AM
Reposted by Lab on a Chip
taghivscience.bsky.social
A luminescence-based point-of-care #HIV viral load test for antiretroviral therapy monitoring pubs.rsc.org/en/content/a... (subscription req for full text)
A luminescence-based point-of-care HIV viral load test for antiretroviral therapy monitoring
Effective monitoring of HIV treatment remains constrained by limited access to affordable, sensitive, and user-friendly viral load diagnostics, particularly in resource-limited settings. To address th...
pubs.rsc.org
October 21, 2025 at 12:50 PM
Reposted by Lab on a Chip
suzumado.bsky.social
www.protein.osaka-u.ac.jp/en/notice/20...
October 17, 2025 at 5:47 AM
labonachip.rsc.org
Full paper available to read via #OpenAccess:
pubs.rsc.org/en/content/a...
Preclinical assessment of pan-influenza A virus CRISPR RNA therapeutics in a human lung alveolus chip
Donald E. Ingber et al
@wyssinstitute.bsky.social
October 16, 2025 at 7:06 AM
labonachip.rsc.org
Available via #OpenAccess.
pubs.rsc.org/en/content/a...
Blood-perfused Vessels-on-Chips stimulated with patient plasma recapitulate endothelial activation and microthrombosis in COVID-19
Huub J. Weener et al
@andriesvdm.bsky.social @rvhelden.bsky.social @middeldorps.bsky.social
October 14, 2025 at 8:39 AM
labonachip.rsc.org
On the inside front cover of issue 20 of Lab on a Chip:
Self-assembled human arteriole-on-a-chip for arterial functionality testing and disease modeling.
#OpenAccess from Yu-Hsiang Hsu et al.
pubs.rsc.org/en/content/a...
inside front cover of issue 20 of Lab on a Chip. Image shows a grey, green and red 3D density model of abstract shapes (An arteriole thrombosis model using self-assembled human arterioles on a chip)
October 13, 2025 at 9:17 AM
labonachip.rsc.org
Available to read via #OpenAccess
The egg-counter: a novel microfluidic platform for characterization of Caenorhabditis elegans egg-laying
pubs.rsc.org/en/content/a...
Patrick C. Phillips et al
@patrickphillips.bsky.social @uoregon.bsky.social @stephenbanse.bsky.social
October 13, 2025 at 8:43 AM
labonachip.rsc.org
On the inside back cover of issue 20 of Lab on a Chip:
A high-sensitivity and clogging-free microfluidic impedance flow cytometer based on three-dimensional hydrodynamic focusing.
Jian Chen, Yi Zhang, Yueying Li et al.
pubs.rsc.org/en/content/a...
Inside back cover of issue 20 of Lab on a Chip. Image of bright particle moving through microfluidic channel.
October 10, 2025 at 8:27 AM
labonachip.rsc.org
On the back cover of issue 20 of Lab on a Chip:
Bistable magnetic valves for selective sweat sampling in wearable microfluidics.
#OpenAccess from Anna Lee, Jonghyun Ha, Jungil Choi et al.
Read now: pubs.rsc.org/en/content/a...
Back cover of issue 20 of Lab on a Chip. Image of a wearable chip on human arm next to magnet.
October 9, 2025 at 7:51 AM
labonachip.rsc.org
On the front cover of issue 20 of Lab on a Chip:
Analysis of and methods for void-free liquid filling of blind microchambers in centrifugal microfluidics.
Mengxi Wu, Junshan Liu et al.
pubs.rsc.org/en/content/a...
Front cover of issue 20 of Lab on a Chip. Image shows Centrifuge channeling pink liquid into microchambers.
October 7, 2025 at 2:02 PM
labonachip.rsc.org
Available to read now via #Open Access.
pubs.rsc.org/en/content/a...
Spatiotemporal temperature control by holographic heating microscopy unveils cellular thermosensitive calcium signalling.
Kotaro Oyama, Madoka Suzuki et al.
October 7, 2025 at 7:38 AM