@kristeenapn.bsky.social
Reposted
A new approach enables real-time tracking of synaptic proteome changes, revealing that toxic tau disrupts postsynaptic structures early, leading to progressive synapse loss in Alzheimer's disease. doi.org/hbmvm3
Discovery shines light on a cascade of events that occurs when toxic tau impacts synapses
A holistic inquiry into how toxic tau impacts synapses provides a new take on the processes that lead to neuronal dysfunction and memory loss in Alzheimer's disease.
medicalxpress.com
January 29, 2026 at 9:50 PM
A new approach enables real-time tracking of synaptic proteome changes, revealing that toxic tau disrupts postsynaptic structures early, leading to progressive synapse loss in Alzheimer's disease. doi.org/hbmvm3
Reposted
Tau #oligomers modulate synapse fate by eliciting progressive bipartite #synapse dysregulation and synapse loss
Kristeen A. Pareja-Navarro, Christina D. King, Grant Kauwe...Tara E. Tracy @buckinstitute.org #AlzheimersDisease #iPSCs
link.springer.com/article/10.1...
Kristeen A. Pareja-Navarro, Christina D. King, Grant Kauwe...Tara E. Tracy @buckinstitute.org #AlzheimersDisease #iPSCs
link.springer.com/article/10.1...
January 22, 2026 at 8:13 PM
Tau #oligomers modulate synapse fate by eliciting progressive bipartite #synapse dysregulation and synapse loss
Kristeen A. Pareja-Navarro, Christina D. King, Grant Kauwe...Tara E. Tracy @buckinstitute.org #AlzheimersDisease #iPSCs
link.springer.com/article/10.1...
Kristeen A. Pareja-Navarro, Christina D. King, Grant Kauwe...Tara E. Tracy @buckinstitute.org #AlzheimersDisease #iPSCs
link.springer.com/article/10.1...
Reposted
Count down: The 5 top accessed research manuscripts of 2024!
#5: KIBRA in tauopathy-related memory loss
https://www.jci.org/articles/view/169064
#5: KIBRA in tauopathy-related memory loss
https://www.jci.org/articles/view/169064
December 27, 2024 at 7:20 PM
Count down: The 5 top accessed research manuscripts of 2024!
#5: KIBRA in tauopathy-related memory loss
https://www.jci.org/articles/view/169064
#5: KIBRA in tauopathy-related memory loss
https://www.jci.org/articles/view/169064