Jeremy Jacobs, MD, MHS, FASCP
@jwjacobs12.bsky.social
Assistant professor, coagulation and transfusion medicine at Vanderbilt. Alum: Mayo Clinic, Yale Lab Med, Vanderbilt, Johns Hopkins | he/him | animal rights advocate
Reposted by Jeremy Jacobs, MD, MHS, FASCP
“This trial adds to the growing body of evidence suggesting no clinically meaningful benefit to albumin administration in the resuscitation of septic patients”
🧪 ICARUS-ED: Early albumin in sepsis?
📉 Minor gains in numbers, no real outcome benefit
💰 30x the cost vs crystalloids
⚠️ Outcomes > optics
🔍 Full breakdown: https://wp.me/pdrP8b-5oc
❤️ Like 🔁 Repost 🔔 Follow for more
#FOAMed #MedX #MedTwitter #MedEd
📉 Minor gains in numbers, no real outcome benefit
💰 30x the cost vs crystalloids
⚠️ Outcomes > optics
🔍 Full breakdown: https://wp.me/pdrP8b-5oc
❤️ Like 🔁 Repost 🔔 Follow for more
#FOAMed #MedX #MedTwitter #MedEd
August 26, 2025 at 2:56 PM
“This trial adds to the growing body of evidence suggesting no clinically meaningful benefit to albumin administration in the resuscitation of septic patients”
Our most recent article hits particularly close to home for me. Had the OBBB passed 10 years ago, it’s unlikely that I would have been able to attend medical school. The new changes threaten to “make the rich, richer”.
Viewpoint: The One Big Beautiful Bill Act's federal loan caps may exacerbate socioeconomic disparities in #MedEd, worsening the Matthew Effect and hindering diversity and equity within the physician workforce.
ja.ma/45xfUKn
ja.ma/45xfUKn
August 25, 2025 at 7:39 PM
Our most recent article hits particularly close to home for me. Had the OBBB passed 10 years ago, it’s unlikely that I would have been able to attend medical school. The new changes threaten to “make the rich, richer”.
Reposted by Jeremy Jacobs, MD, MHS, FASCP
The Annals of Internal Medicine has refused US health secretary Robert F Kennedy Jr’s demand to retract a study that found that vaccines containing the adjuvant aluminium hydroxide did not increase the incidence of 50 chronic disorders, including autism and asthma
www.bmj.com/content/390/...
www.bmj.com/content/390/...
August 18, 2025 at 8:07 PM
The Annals of Internal Medicine has refused US health secretary Robert F Kennedy Jr’s demand to retract a study that found that vaccines containing the adjuvant aluminium hydroxide did not increase the incidence of 50 chronic disorders, including autism and asthma
www.bmj.com/content/390/...
www.bmj.com/content/390/...
Reposted by Jeremy Jacobs, MD, MHS, FASCP
New Opinion article by @jwjacobs12.bsky.social and Shazia Khan: "Erasing the evidence: United States climate rollbacks and the implications for public health"
journals.plos.org/climate/arti...
journals.plos.org/climate/arti...
July 21, 2025 at 8:52 AM
New Opinion article by @jwjacobs12.bsky.social and Shazia Khan: "Erasing the evidence: United States climate rollbacks and the implications for public health"
journals.plos.org/climate/arti...
journals.plos.org/climate/arti...
Reposted by Jeremy Jacobs, MD, MHS, FASCP
Blood is shared across legal borders to save lives.
Equitable and efficient movement of blood is guided by science and justice and must be insulated from ideologically motivated practices, argue co-authors @jwjacobs12.bsky.social @aabbupdates.bsky.social
onlinelibrary.wiley.com/doi/10.1111/...
Equitable and efficient movement of blood is guided by science and justice and must be insulated from ideologically motivated practices, argue co-authors @jwjacobs12.bsky.social @aabbupdates.bsky.social
onlinelibrary.wiley.com/doi/10.1111/...
Blood Borders: State laws, vaccine misinformation, and the threat to the United States blood supply
Click on the article title to read more.
onlinelibrary.wiley.com
June 18, 2025 at 12:53 AM
Blood is shared across legal borders to save lives.
Equitable and efficient movement of blood is guided by science and justice and must be insulated from ideologically motivated practices, argue co-authors @jwjacobs12.bsky.social @aabbupdates.bsky.social
onlinelibrary.wiley.com/doi/10.1111/...
Equitable and efficient movement of blood is guided by science and justice and must be insulated from ideologically motivated practices, argue co-authors @jwjacobs12.bsky.social @aabbupdates.bsky.social
onlinelibrary.wiley.com/doi/10.1111/...
In this Nature Medicine commentary @drgsbooth1.bsky.social and I discuss how the current political environment in the USA, including the weaponization of immigration enforcement, is impacting global scientific research, and the implications for science.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
How US politics is undermining global science
Nature Medicine - How US politics is undermining global science
www.nature.com
May 23, 2025 at 12:50 PM
In this Nature Medicine commentary @drgsbooth1.bsky.social and I discuss how the current political environment in the USA, including the weaponization of immigration enforcement, is impacting global scientific research, and the implications for science.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
🩸Would you want “unvaccinated” blood? Some patients now demand it—and lawmakers are listening.
Our new Annals piece warns why this shift could endanger blood safety, amplify misinformation, and erode public trust.
Read: www.acpjournals.org/doi/10.7326/...
#BloodSafety #Bioethics #Misinformation
Our new Annals piece warns why this shift could endanger blood safety, amplify misinformation, and erode public trust.
Read: www.acpjournals.org/doi/10.7326/...
#BloodSafety #Bioethics #Misinformation
Medical, Societal, and Ethical Considerations for Directed Blood Donation in 2025 | Annals of Internal Medicine
In the United States and other high-income countries, blood donation primarily relies on anonymous, voluntary donors. However, directed blood donation—where people donate for a specific recipient—has ...
www.acpjournals.org
May 14, 2025 at 10:37 PM
🩸Would you want “unvaccinated” blood? Some patients now demand it—and lawmakers are listening.
Our new Annals piece warns why this shift could endanger blood safety, amplify misinformation, and erode public trust.
Read: www.acpjournals.org/doi/10.7326/...
#BloodSafety #Bioethics #Misinformation
Our new Annals piece warns why this shift could endanger blood safety, amplify misinformation, and erode public trust.
Read: www.acpjournals.org/doi/10.7326/...
#BloodSafety #Bioethics #Misinformation
Reposted by Jeremy Jacobs, MD, MHS, FASCP
In other words, the US government has suspended free speech.
Effective immediately, the government says it will begin screening immigrant social media for activity that officials think indicates support for antisemitism.
U.S. says it is now monitoring immigrants' social media for antisemitism
Effective immediately, the government says it will begin screening immigrant social media for activity that officials think indicates support for antisemitism.
www.npr.org
April 9, 2025 at 10:55 PM
In other words, the US government has suspended free speech.
Check out our recent viewpoint in @jama.com. The appointment of David Geier to lead the “vaccine and autism link” study, the forced resignation of Peter Marks at the FDA, and the overall leadership of RFK Jr. and Trump are literally killing Americans. We must resist this new world.
"Public health institutions must now rebuild confidence in vaccines against a backdrop of deep polarization and growing scientific illiteracy."
This Viewpoint discusses the growing influence of vaccine skeptics within public health institutions. #MedSky
This Viewpoint discusses the growing influence of vaccine skeptics within public health institutions. #MedSky
Unreliable Vaccine Information and the Erosion of Science
This Viewpoint explores how appointing vaccine skeptics to positions of power in the US government contributes to the spread of unreliable information, subverts public confidence in vaccines, and unde...
jamanetwork.com
April 9, 2025 at 10:17 PM
Check out our recent viewpoint in @jama.com. The appointment of David Geier to lead the “vaccine and autism link” study, the forced resignation of Peter Marks at the FDA, and the overall leadership of RFK Jr. and Trump are literally killing Americans. We must resist this new world.
Reposted by Jeremy Jacobs, MD, MHS, FASCP
The Health Secretary is promoting quack doctors in the midst of a measles outbreak and literally nothing was more predictable.
April 7, 2025 at 1:11 AM
The Health Secretary is promoting quack doctors in the midst of a measles outbreak and literally nothing was more predictable.
Reposted by Jeremy Jacobs, MD, MHS, FASCP
Here is an open letter signed from UChicago AAUP signed by over 200 faculty to our administration on what we believe this moment requires:
uchicagoaaup.wordpress.com
uchicagoaaup.wordpress.com
March 10, 2025 at 3:15 PM
Here is an open letter signed from UChicago AAUP signed by over 200 faculty to our administration on what we believe this moment requires:
uchicagoaaup.wordpress.com
uchicagoaaup.wordpress.com
Reposted by Jeremy Jacobs, MD, MHS, FASCP
EU foreign policy chief:
“.. Today, it became clear that the free world needs a new leader.”
@kajakallas.bsky.social
“.. Today, it became clear that the free world needs a new leader.”
@kajakallas.bsky.social
February 28, 2025 at 8:57 PM
EU foreign policy chief:
“.. Today, it became clear that the free world needs a new leader.”
@kajakallas.bsky.social
“.. Today, it became clear that the free world needs a new leader.”
@kajakallas.bsky.social
Reposted by Jeremy Jacobs, MD, MHS, FASCP
In this issue of NEJM Evidence, @jwjacobs12.bsky.social and I interpret the recent individual-patient meta-analysis for RBC transfusion in myocardial infarction by Carson et al and make a case for nuanced interpretation evidence.nejm.org/doi/full/10.... #medsky #transfusion
Transfusion Strategies in Myocardial Ischemia — Treat Patients, Not Numbers
Consider a relatively common clinical scenario: a 55-year-old man arrives in the emergency
department after experiencing crushing retrosternal chest pain while shoveling the
first snowfall of winte...
evidence.nejm.org
January 29, 2025 at 12:48 AM
In this issue of NEJM Evidence, @jwjacobs12.bsky.social and I interpret the recent individual-patient meta-analysis for RBC transfusion in myocardial infarction by Carson et al and make a case for nuanced interpretation evidence.nejm.org/doi/full/10.... #medsky #transfusion
Reposted by Jeremy Jacobs, MD, MHS, FASCP
H and B Blood Antigens are Essential for In Vitro Replication of GII.2 Human Norovirus
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
H and B Blood Antigens are Essential for In Vitro Replication of GII.2 Human Norovirus
Human norovirus (HuNoV) is a major cause of enteric infectious gastroenteritis and is classified into several genotypes based on its capsid protein amino acid sequence and nucleotide sequence of the polymerase gene.
buff.ly
December 23, 2024 at 3:33 PM
H and B Blood Antigens are Essential for In Vitro Replication of GII.2 Human Norovirus
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Reposted by Jeremy Jacobs, MD, MHS, FASCP
Our correspondence with @natureportfolio.bsky.social advocating that scholarly journals support direct link-sharing to #Bluesky amidst the exodus of academic communities from X (formerly Twitter)
@drgsbooth1.bsky.social @jwjacobs12.bsky.social @path-brian.bsky.social
www.nature.com/articles/d41...
@drgsbooth1.bsky.social @jwjacobs12.bsky.social @path-brian.bsky.social
www.nature.com/articles/d41...
December 17, 2024 at 3:04 PM
Our correspondence with @natureportfolio.bsky.social advocating that scholarly journals support direct link-sharing to #Bluesky amidst the exodus of academic communities from X (formerly Twitter)
@drgsbooth1.bsky.social @jwjacobs12.bsky.social @path-brian.bsky.social
www.nature.com/articles/d41...
@drgsbooth1.bsky.social @jwjacobs12.bsky.social @path-brian.bsky.social
www.nature.com/articles/d41...
Excited to share our recent study in which we assessed whether iodinated radiocontrast media (as might be given for a CT scan) interferes with ADAMTS13 activity via the gold standard FRET method - it doesn’t, though read the open access paper for caveats. academic.oup.com/ajcp/advance...
Evaluating the potential for iodinated radiocontrast agents to interfere with ADAMTS13 activity testing via fluorescence resonance energy transfer methodology
AbstractObjectives. Fluorescence resonance energy transfer (FRET)–based ADAMTS13 activity assays are critical for the diagnosis of thrombotic thrombocytope
academic.oup.com
December 5, 2024 at 10:14 PM
Excited to share our recent study in which we assessed whether iodinated radiocontrast media (as might be given for a CT scan) interferes with ADAMTS13 activity via the gold standard FRET method - it doesn’t, though read the open access paper for caveats. academic.oup.com/ajcp/advance...
Reposted by Jeremy Jacobs, MD, MHS, FASCP
Tranexamic acid did not prevent bleeding or increase clotting in this ~600 patient RCT of heme malignancy patients (TXA was given 1 g IV every 8 hours or 1.5 g orally every 8 hours)🤷🏽♂️
Which is too bad--we don't have a tonne to offer these patients.. :(
www.thelancet.com/journals/lan... #transfusion
Which is too bad--we don't have a tonne to offer these patients.. :(
www.thelancet.com/journals/lan... #transfusion
December 5, 2024 at 4:30 AM
Tranexamic acid did not prevent bleeding or increase clotting in this ~600 patient RCT of heme malignancy patients (TXA was given 1 g IV every 8 hours or 1.5 g orally every 8 hours)🤷🏽♂️
Which is too bad--we don't have a tonne to offer these patients.. :(
www.thelancet.com/journals/lan... #transfusion
Which is too bad--we don't have a tonne to offer these patients.. :(
www.thelancet.com/journals/lan... #transfusion
Reposted by Jeremy Jacobs, MD, MHS, FASCP
Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪
There are already many articles for which there is more attention on Bluesky than on other comparable micro-blogging sites, meaning the academic community and the general public have clearly adopted Bluesky as one of its core places to disseminate and discuss new research.
A Place of Joy.
A Place of Joy.
December 3, 2024 at 2:10 PM
Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪
Reposted by Jeremy Jacobs, MD, MHS, FASCP
Good news, Altmetric has now started watching BlueSky for mentions of publications. And by the way, provides an easy comparison between this and the old site for a recent preprint of mine which I posted simultaneousl at both. Numbers speak by themselves !
December 2, 2024 at 6:35 PM
Good news, Altmetric has now started watching BlueSky for mentions of publications. And by the way, provides an easy comparison between this and the old site for a recent preprint of mine which I posted simultaneousl at both. Numbers speak by themselves !
Reposted by Jeremy Jacobs, MD, MHS, FASCP
🩸Platelets!
Lifespan 7-10 days
150-450 × 10⁹/L
Stimulated by TPO
1/3 sequestered in spleen
Receptors:
GpIIbIIIa -> fibrinogen
GPIb-IX-V -> vWF
P2Y12 -> ADP
Granules:
Alpha = fibrinogen, vWF, V, VEGF, PF4, PDGF, P-selectin
Dense = ADP, Ca, Serotonin
#hemesky #MedSky
van der Meijden et al, 2019
Lifespan 7-10 days
150-450 × 10⁹/L
Stimulated by TPO
1/3 sequestered in spleen
Receptors:
GpIIbIIIa -> fibrinogen
GPIb-IX-V -> vWF
P2Y12 -> ADP
Granules:
Alpha = fibrinogen, vWF, V, VEGF, PF4, PDGF, P-selectin
Dense = ADP, Ca, Serotonin
#hemesky #MedSky
van der Meijden et al, 2019
December 1, 2024 at 1:05 PM
Reposted by Jeremy Jacobs, MD, MHS, FASCP
Wonderful article by my mentor showing cognitive biases persist in AI chatbots, replicates known studies on biases in human and AI LLMs for comparison. Evidence that LLMs are inheriting some of our biases, in some cases quite strongly so ai.nejm.org/doi/full/10....
#mlsky #ai
#mlsky #ai
December 1, 2024 at 1:44 AM
Wonderful article by my mentor showing cognitive biases persist in AI chatbots, replicates known studies on biases in human and AI LLMs for comparison. Evidence that LLMs are inheriting some of our biases, in some cases quite strongly so ai.nejm.org/doi/full/10....
#mlsky #ai
#mlsky #ai
Advocating for @altmetric.com to include #Bluesky in its tracking
@drgsbooth1.bsky.social @sraza.bsky.social @path-brian.bsky.social
@drgsbooth1.bsky.social @sraza.bsky.social @path-brian.bsky.social
November 27, 2024 at 11:15 PM
Advocating for @altmetric.com to include #Bluesky in its tracking
@drgsbooth1.bsky.social @sraza.bsky.social @path-brian.bsky.social
@drgsbooth1.bsky.social @sraza.bsky.social @path-brian.bsky.social
A fantastic person/physician/researcher to follow!
Hello #BlueSky #MedSky! Figured I would give these skies a venture. Briefly, I’m Sara, a #urology resident at Mayo Clinic Florida. Passionate about #medicalhumanities, advocating for #womeninmedicine #womeninsurgery, & #medicaleducation. Ask me about #medicalillustration & or my kid’s book!
November 19, 2024 at 2:02 AM
A fantastic person/physician/researcher to follow!
Reposted by Jeremy Jacobs, MD, MHS, FASCP
How do we screen for hemoglobin abnormality in the US?
-All state newborn screens evaluate hemoglobin
-pediatric-age immigrants often get newborn when they come to US
-Thalassemia trait often identified in pregnant patients or patients with persistent microcytosis after correcting iron deficiency
-All state newborn screens evaluate hemoglobin
-pediatric-age immigrants often get newborn when they come to US
-Thalassemia trait often identified in pregnant patients or patients with persistent microcytosis after correcting iron deficiency
November 17, 2024 at 4:35 PM
How do we screen for hemoglobin abnormality in the US?
-All state newborn screens evaluate hemoglobin
-pediatric-age immigrants often get newborn when they come to US
-Thalassemia trait often identified in pregnant patients or patients with persistent microcytosis after correcting iron deficiency
-All state newborn screens evaluate hemoglobin
-pediatric-age immigrants often get newborn when they come to US
-Thalassemia trait often identified in pregnant patients or patients with persistent microcytosis after correcting iron deficiency
The best girls
November 10, 2024 at 4:01 AM
The best girls