Joe Sneath Thompson
jsneaththompson.bsky.social
Joe Sneath Thompson
@jsneaththompson.bsky.social
Reposted by Joe Sneath Thompson
This project has been with me since day 1 in the lab - a long journey of challenges, growth & incredible teamwork 🚀

So proud of @gmaci.bsky.social team for pushing this work to the finish line! Thks to collaborators (#Barbacid & #FSanchezVega labs) and @caixaresearch.bsky.social for their support
November 28, 2025 at 1:07 PM
Reposted by Joe Sneath Thompson
📢 New preprint out!

We are thrilled to introduce our framework to track #ongoingCIN by leveraging single-cell genomics and CIN signatures:

www.biorxiv.org/content/10.1...
Tracking ongoing chromosomal instability using single-cell whole-genome sequencing
Chromosomal instability (CIN) generates aneuploid genomes that are characteristic of most cancers. While bulk genome sequencing reveals historical CIN, it lacks the resolution to identify ongoing CIN ...
www.biorxiv.org
November 28, 2025 at 1:07 PM
Reposted by Joe Sneath Thompson
The paper is published in @natgenet.nature.com. First authors: @bhernando.bsky.social, @jsneaththompson.bsky.social and Laura Madrid. With collaborations from Tailor Bio and @cam.ac.uk

Funding: @saludisciii.bsky.social @cienciagob.bsky.social  @cruk-ci.bsky.social  y @lacaixa.bsky.social
June 23, 2025 at 4:14 PM
Reposted by Joe Sneath Thompson
The days of one-size-fits-all chemotherapy are ending.

Researchers at our Institute, @cniostopcancer.bsky.social & Tailor Bio have developed a test that predicts resistance to common chemo drugs — paving the way for personalised cancer treatment.

Find out more 👉 www.cruk.cam.ac.uk/news/scienti...
June 23, 2025 at 9:00 AM
Reposted by Joe Sneath Thompson
📢OUT TODAY @natgenet.nature.com

📰Predicting resistance to chemotherapy using chromosomal instability signatures.

By @jsneaththompson.bsky.social, @gmaci.bsky.social and colleagues.

⬇️

www.nature.com/articles/s41...
June 23, 2025 at 2:18 PM
Reposted by Joe Sneath Thompson
🚨Chemo treatment upgrade!🚨

Check out our approach to modernise chemotherapy treatment published today in @natgenet.nature.com. From @cniostopcancer.bsky.social #TailorBio @cruk-ci.bsky.social www.nature.com/articles/s41... More details 👇
www.nature.com
June 23, 2025 at 9:03 AM