JP Lopes
@jplopesmd.bsky.social
The immune system is everywhere. Al at CWRU/UH RBC in Cleveland, OH. Icahn School of Medicine at Mount Sinai, NYC, NY alumn. All opinions are personal.
Reposted by JP Lopes
Important talk on disparities in diagnosis of #inbornerrorsofimmunity happening now at #CIS2025
May 2, 2025 at 2:18 PM
Important talk on disparities in diagnosis of #inbornerrorsofimmunity happening now at #CIS2025
Reposted by JP Lopes
#CIS2025 is starting! For those attending join us tomorrow, Friday, for a lunch discussion on publishing including information about our new journal @jhumimmunity.org #CIS, #IAPIDS
May 1, 2025 at 4:41 PM
#CIS2025 is starting! For those attending join us tomorrow, Friday, for a lunch discussion on publishing including information about our new journal @jhumimmunity.org #CIS, #IAPIDS
Reposted by JP Lopes
Just published @science.org
A basis—lung inflammation—for #LongCovid (PASC) in the experimental model, and a potential therapy
[driven by alveolar macrophages and loss of their peroxisomes (Figure)]
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
A basis—lung inflammation—for #LongCovid (PASC) in the experimental model, and a potential therapy
[driven by alveolar macrophages and loss of their peroxisomes (Figure)]
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
March 6, 2025 at 7:00 PM
Just published @science.org
A basis—lung inflammation—for #LongCovid (PASC) in the experimental model, and a potential therapy
[driven by alveolar macrophages and loss of their peroxisomes (Figure)]
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
A basis—lung inflammation—for #LongCovid (PASC) in the experimental model, and a potential therapy
[driven by alveolar macrophages and loss of their peroxisomes (Figure)]
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
This would be such a significant development. You may think about norovirus as a "cruise nuisance" but it can be very severe and life-changing in a large slice of immunodeficient patients (even if we could not guarantee their immunity with the vaccine, reducing transmission could help).
In the US alone, each year, norovirus causes ~20 million acute gastroenteritis cases, 70,000 hospitalizations, up to 800 deaths, at a cost of ~$10.6 billion annually.
An pill vaccine shows considerable promise in a clinical trial, establishing mucosal immunity
www.science.org/doi/10.1126/...
An pill vaccine shows considerable promise in a clinical trial, establishing mucosal immunity
www.science.org/doi/10.1126/...
An oral norovirus vaccine tablet was safe and elicited mucosal immunity in older adults in a phase 1b clinical trial
An oral norovirus vaccine tablet is safe and induces strong mucosal and systemic immune responses in adults aged 55 to 80 years.
www.science.org
March 6, 2025 at 12:30 AM
This would be such a significant development. You may think about norovirus as a "cruise nuisance" but it can be very severe and life-changing in a large slice of immunodeficient patients (even if we could not guarantee their immunity with the vaccine, reducing transmission could help).
Reposted by JP Lopes
West Texas measles outbreak latest count: 159
Looks to be slowing down. CDC sent out a response team this week, too, which will hopefully help even more.
Looks to be slowing down. CDC sent out a response team this week, too, which will hopefully help even more.
March 4, 2025 at 9:06 PM
West Texas measles outbreak latest count: 159
Looks to be slowing down. CDC sent out a response team this week, too, which will hopefully help even more.
Looks to be slowing down. CDC sent out a response team this week, too, which will hopefully help even more.
These days are so intense but honored to present and to moderate sessions, and happy to see colleagues and friends. In a time where science is being tested to limits not previously seen, it is reassuring to see so many brilliant people together and that we are, for now, in great hands. #AAAAI25
March 4, 2025 at 1:10 AM
These days are so intense but honored to present and to moderate sessions, and happy to see colleagues and friends. In a time where science is being tested to limits not previously seen, it is reassuring to see so many brilliant people together and that we are, for now, in great hands. #AAAAI25
Had an incredible time in beautiful San Diego at our annual AAAAI meeting, this time a joint congress with WAO (with the extra pride of seeing Portuguese Professor Mário Morais de Almeida as WAO president). #AAAAI25
March 4, 2025 at 1:08 AM
Had an incredible time in beautiful San Diego at our annual AAAAI meeting, this time a joint congress with WAO (with the extra pride of seeing Portuguese Professor Mário Morais de Almeida as WAO president). #AAAAI25