Jonna Singh
@jonnasingh.bsky.social
Interoception, psychedelics, pain, flashy neurons, and everything in between
prev basal ganglia and birds
Postdoc @ Andermann lab
prev basal ganglia and birds
Postdoc @ Andermann lab
Thanks @thetransmitter.bsky.social and to my lab for brightening my week with this rising stars in neuroscience award!! Wish I could be in #sfn to celebrate in the sun.
Wonderful list of people: www.thetransmitter.org/early-career...
Wonderful list of people: www.thetransmitter.org/early-career...
November 17, 2025 at 4:46 PM
Thanks @thetransmitter.bsky.social and to my lab for brightening my week with this rising stars in neuroscience award!! Wish I could be in #sfn to celebrate in the sun.
Wonderful list of people: www.thetransmitter.org/early-career...
Wonderful list of people: www.thetransmitter.org/early-career...
Woulda guessed 50%, glass half full kinda person
Hundreds of animal studies about early brain injury after subarachnoid hemorrhage show signs of image manipulation or duplication, which may have stalled research into treatments.
By @lauren-schneider.com
#neuroskyence
www.thetransmitter.org/publishing/i...
By @lauren-schneider.com
#neuroskyence
www.thetransmitter.org/publishing/i...
Image integrity issues create new headache for subarachnoid hemorrhage research
First-time sleuths found potentially problematic images in hundreds of papers about early brain injury after subarachnoid hemorrhage.
www.thetransmitter.org
November 2, 2025 at 2:45 PM
Woulda guessed 50%, glass half full kinda person
Reposted by Jonna Singh
ADD YOUR THOUGHTS ON LIMITING STUDENT VISA TO FOUR YEARS
Comment period ends September 29th
www.federalregister.gov/documents/20...
1/2
Comment period ends September 29th
www.federalregister.gov/documents/20...
1/2
Establishing a Fixed Time Period of Admission and an Extension of Stay Procedure for Nonimmigrant Academic Students, Exchange Visitors, and Representatives of Foreign Information Media
Unlike most nonimmigrant classifications, which are admitted for a fixed time period, aliens in the F (academic student), J (exchange visitor), and most I (representatives of foreign information media...
www.federalregister.gov
September 20, 2025 at 10:38 AM
ADD YOUR THOUGHTS ON LIMITING STUDENT VISA TO FOUR YEARS
Comment period ends September 29th
www.federalregister.gov/documents/20...
1/2
Comment period ends September 29th
www.federalregister.gov/documents/20...
1/2
graphical abstract goes hard
June 17, 2025 at 2:24 AM
graphical abstract goes hard
Reposted by Jonna Singh
Wild!
Stephen, Praneel and their team use fluorescence lifetime imaging and various manipulations to show that, in male mice, both mating drive and hypothalamic tonic dopamine release drop after a successful mating and gradually recover over the next week, paralleling the recovery in sperm count.
Stephen, Praneel and their team use fluorescence lifetime imaging and various manipulations to show that, in male mice, both mating drive and hypothalamic tonic dopamine release drop after a successful mating and gradually recover over the next week, paralleling the recovery in sperm count.
I am excited to share our preprint on how hypothalamic dopamine neurons govern slow changes in motivation over days! Below are our findings:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Slow-Timescale Regulation of Dopamine Release and Mating Drive over Days
The rise and fall of motivational states may take place over timescales as long as many days. We used mouse mating behavior to model how the brain orchestrates slow-timescale changes in motivation. Ma...
www.biorxiv.org
June 2, 2025 at 7:26 PM
Wild!
Stephen, Praneel and their team use fluorescence lifetime imaging and various manipulations to show that, in male mice, both mating drive and hypothalamic tonic dopamine release drop after a successful mating and gradually recover over the next week, paralleling the recovery in sperm count.
Stephen, Praneel and their team use fluorescence lifetime imaging and various manipulations to show that, in male mice, both mating drive and hypothalamic tonic dopamine release drop after a successful mating and gradually recover over the next week, paralleling the recovery in sperm count.
Featuring 2p FLIM to track DA levels over days, and a demonstration that a neurons molecular identity is pretty labile @stephen-zhang.bsky.social @markandermann.bsky.social
P.S: Praneel will be applying to MD PhD and is an absolute beast. Systems neuro labs don’t miss out!!
P.S: Praneel will be applying to MD PhD and is an absolute beast. Systems neuro labs don’t miss out!!
I am excited to share our preprint on how hypothalamic dopamine neurons govern slow changes in motivation over days! Below are our findings:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Slow-Timescale Regulation of Dopamine Release and Mating Drive over Days
The rise and fall of motivational states may take place over timescales as long as many days. We used mouse mating behavior to model how the brain orchestrates slow-timescale changes in motivation. Ma...
www.biorxiv.org
June 3, 2025 at 11:13 PM
Featuring 2p FLIM to track DA levels over days, and a demonstration that a neurons molecular identity is pretty labile @stephen-zhang.bsky.social @markandermann.bsky.social
P.S: Praneel will be applying to MD PhD and is an absolute beast. Systems neuro labs don’t miss out!!
P.S: Praneel will be applying to MD PhD and is an absolute beast. Systems neuro labs don’t miss out!!
Reposted by Jonna Singh
URGENT! Contact your senators today to advocate to fund science agencies and programs!
The Senate Appropriations Committee & its subcommittees are writing appropriation bills for the federal FY26 budget now.
Here's how you can help: esa.org/esablog/2025...
The Senate Appropriations Committee & its subcommittees are writing appropriation bills for the federal FY26 budget now.
Here's how you can help: esa.org/esablog/2025...
June 2, 2025 at 5:18 PM
URGENT! Contact your senators today to advocate to fund science agencies and programs!
The Senate Appropriations Committee & its subcommittees are writing appropriation bills for the federal FY26 budget now.
Here's how you can help: esa.org/esablog/2025...
The Senate Appropriations Committee & its subcommittees are writing appropriation bills for the federal FY26 budget now.
Here's how you can help: esa.org/esablog/2025...
Reposted by Jonna Singh
I know it's not very helpful, but I find myself thinking about those who criticized Nature's and Scientific American's Harris endorsement on the grounds that "science should stay out of politics." I think about those people quite a lot.
NBC News confirms: The Trump admin aims to cut all remaining ties with Harvard and the White House intends to ask all federal agencies to seek ways to end its contracts with the school today. @msnbc.com
May 27, 2025 at 5:19 PM
I know it's not very helpful, but I find myself thinking about those who criticized Nature's and Scientific American's Harris endorsement on the grounds that "science should stay out of politics." I think about those people quite a lot.
It’s is practically guaranteed that what is happening to Harvard WILL happen to your favorite R1 institution if we don’t continue to engage our local representatives.
May 24, 2025 at 10:21 PM
It’s is practically guaranteed that what is happening to Harvard WILL happen to your favorite R1 institution if we don’t continue to engage our local representatives.
Reminder: Bluesky is an echo chamber.
As useful as it is to get informed and feel support on here, it’s time to get uncomfortable and speak up *in real life*.
Talk to those who are not here. Be ready to explain these catastrophes. Add YOUR grain of salt to the mobilization process. It matters.
As useful as it is to get informed and feel support on here, it’s time to get uncomfortable and speak up *in real life*.
Talk to those who are not here. Be ready to explain these catastrophes. Add YOUR grain of salt to the mobilization process. It matters.
JUST IN: International students make up more than a quarter of Harvard University's student body. Harvard says the government's actions, which could cut off a major revenue stream, are "unlawful."
Trump administration revokes Harvard's ability to enroll international students
International students make up more than a quarter of Harvard University's student body. Harvard says the government's actions, which could cut off a major revenue stream, are "unlawful."
www.npr.org
May 23, 2025 at 12:24 PM
Reminder: Bluesky is an echo chamber.
As useful as it is to get informed and feel support on here, it’s time to get uncomfortable and speak up *in real life*.
Talk to those who are not here. Be ready to explain these catastrophes. Add YOUR grain of salt to the mobilization process. It matters.
As useful as it is to get informed and feel support on here, it’s time to get uncomfortable and speak up *in real life*.
Talk to those who are not here. Be ready to explain these catastrophes. Add YOUR grain of salt to the mobilization process. It matters.
Positional molecular markers guide the regeneration of the correct body parts in axolotls.
Go axolotl gang!
Go axolotl gang!
Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury.
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
May 22, 2025 at 10:32 AM
Positional molecular markers guide the regeneration of the correct body parts in axolotls.
Go axolotl gang!
Go axolotl gang!
Reposted by Jonna Singh
Under 65 years old? No Novovax COVID vaccine for you this year.
As expected, the Republicans have enabled RFK Jr. and his coterie of antivax grifters to take away your right to make your own medical decisions in consultation with your doctor.
Gift Link: www.nytimes.com/2025/05/17/h...
As expected, the Republicans have enabled RFK Jr. and his coterie of antivax grifters to take away your right to make your own medical decisions in consultation with your doctor.
Gift Link: www.nytimes.com/2025/05/17/h...
May 18, 2025 at 4:11 AM
Under 65 years old? No Novovax COVID vaccine for you this year.
As expected, the Republicans have enabled RFK Jr. and his coterie of antivax grifters to take away your right to make your own medical decisions in consultation with your doctor.
Gift Link: www.nytimes.com/2025/05/17/h...
As expected, the Republicans have enabled RFK Jr. and his coterie of antivax grifters to take away your right to make your own medical decisions in consultation with your doctor.
Gift Link: www.nytimes.com/2025/05/17/h...
Reposted by Jonna Singh
Dozens of responses to my essay summarized.
1. Why aren’t scientists in an uproar?
2. Most Americans don't know that defunding science will make their lives worse.
Bluesky, tell your neighbors, science matters. Scientists, roar.
🧪💙📚 #scicomm #science 🌎 🔬 ⚒️
theconversation.com/unprecedente...
1. Why aren’t scientists in an uproar?
2. Most Americans don't know that defunding science will make their lives worse.
Bluesky, tell your neighbors, science matters. Scientists, roar.
🧪💙📚 #scicomm #science 🌎 🔬 ⚒️
theconversation.com/unprecedente...
Unprecedented cuts to the National Science Foundation endanger research that improves economic growth, national security and your life
The Trump administration has terminated hundreds of federal grants that support engineering, biology, geology, computer science, STEM education and much more.
theconversation.com
May 16, 2025 at 3:19 PM
Dozens of responses to my essay summarized.
1. Why aren’t scientists in an uproar?
2. Most Americans don't know that defunding science will make their lives worse.
Bluesky, tell your neighbors, science matters. Scientists, roar.
🧪💙📚 #scicomm #science 🌎 🔬 ⚒️
theconversation.com/unprecedente...
1. Why aren’t scientists in an uproar?
2. Most Americans don't know that defunding science will make their lives worse.
Bluesky, tell your neighbors, science matters. Scientists, roar.
🧪💙📚 #scicomm #science 🌎 🔬 ⚒️
theconversation.com/unprecedente...
Reposted by Jonna Singh
TOMORROW 12pm PT/3pm ET, academic workers across the country are organizing to call Senators and Representatives, particularly from historically “red” districts, to sign onto to letters supporting federal research funding. Register here to join the phonebank: form.laborbase.org/251246245216...
Phonebank to Support Federal Research Funding on 5/13
Please click the link to complete this form.
form.laborbase.org
May 12, 2025 at 1:52 PM
TOMORROW 12pm PT/3pm ET, academic workers across the country are organizing to call Senators and Representatives, particularly from historically “red” districts, to sign onto to letters supporting federal research funding. Register here to join the phonebank: form.laborbase.org/251246245216...
Hardest surgery I’ve seen to get the coolest brainstem imaging I’ve seen!
Rachel’s paper shows interoceptive information, in particular feeding-related info, is organized across PBN
Rachel’s paper shows interoceptive information, in particular feeding-related info, is organized across PBN
I’m so excited to share our preprint on how brainstem neurons sense and integrate multiple body signals during food consumption. We imaged 1000s of neurons across the lateral parabrachial nucleus (LPBN) in behaving mice. www.biorxiv.org/content/10.1...
Brainstem sensing of multiple body signals during food consumption
Studies of body-to-brain communication often examine one stimulus or organ at a time, yet the brain must integrate many body signals during behavior. For example, food consumption generates diverse or...
www.biorxiv.org
May 10, 2025 at 1:28 PM
Hardest surgery I’ve seen to get the coolest brainstem imaging I’ve seen!
Rachel’s paper shows interoceptive information, in particular feeding-related info, is organized across PBN
Rachel’s paper shows interoceptive information, in particular feeding-related info, is organized across PBN
Reposted by Jonna Singh
A thread: NIH Fellows United is committed to showing up, even when leadership won’t. 🧪
May 9, 2025 at 6:57 PM
A thread: NIH Fellows United is committed to showing up, even when leadership won’t. 🧪
Pretty ironic that those who stand to gain the most from a quantitative arm are biologists given the reformatting of the field with new tech.
1/15) We had an interesting conversation on BlueSky here last week about why there's not more of an interface between theory and experiments in neuroscience.
Thanks to those who chimed in!
My broader take is shown below.
A🧵on the experience that led me to this take:
🧠📈 🧪
Thanks to those who chimed in!
My broader take is shown below.
A🧵on the experience that led me to this take:
🧠📈 🧪
I largely agree with this, but mostly blame the fact that we don’t include formal modelling in the core neuroscience curriculum.
May 6, 2025 at 12:42 PM
Pretty ironic that those who stand to gain the most from a quantitative arm are biologists given the reformatting of the field with new tech.
Reposted by Jonna Singh
One of the most inspiring essays I’ve read on resistance. www.vnews.com/Column-A-tim...
Column: A time for bravery
It is no longer enough to be good; it is time to be brave.
www.vnews.com
May 4, 2025 at 2:31 AM
One of the most inspiring essays I’ve read on resistance. www.vnews.com/Column-A-tim...
Reposted by Jonna Singh
I am extremely pleased to share this feature articulating why I have lost my sanity lately. www.science.org/content/arti...
U.S. scientists’ lives and careers are being upended. Here are five of their stories
As the second Trump administration sends U.S. science into upheaval, countless researchers are fighting for their futures
www.science.org
May 3, 2025 at 10:23 PM
I am extremely pleased to share this feature articulating why I have lost my sanity lately. www.science.org/content/arti...
Reposted by Jonna Singh
🚀🔬🦠 Releasing 🤖Cellpose-SAM🤖, a cellular segmentation algorithm with superhuman generalization 🦸♀️. Try it now on 🤗 huggingface.co/spaces/mouse...
paper: www.biorxiv.org/content/10.1...
w/ @computingnature.bsky.social 1/n
paper: www.biorxiv.org/content/10.1...
w/ @computingnature.bsky.social 1/n
May 3, 2025 at 7:12 PM
🚀🔬🦠 Releasing 🤖Cellpose-SAM🤖, a cellular segmentation algorithm with superhuman generalization 🦸♀️. Try it now on 🤗 huggingface.co/spaces/mouse...
paper: www.biorxiv.org/content/10.1...
w/ @computingnature.bsky.social 1/n
paper: www.biorxiv.org/content/10.1...
w/ @computingnature.bsky.social 1/n
Reposted by Jonna Singh
The scientific community is at a pivotal moment right now. And we are seeing things start to shift. Now is the time for scientists and scientific institutions to step up. No one is coming to save us. 🧵
May 2, 2025 at 2:57 PM
The scientific community is at a pivotal moment right now. And we are seeing things start to shift. Now is the time for scientists and scientific institutions to step up. No one is coming to save us. 🧵
I 💙 seeing team science makin it happen
After 7 years, thrilled to finally share our #MICrONS functional connectomics results!
We recorded activity from ~75K neurons in the visual cortex of a single mouse, then mapped its wiring using electron microscopy.
nature.com/immersive/d42859-025-00001-w/index.html
We recorded activity from ~75K neurons in the visual cortex of a single mouse, then mapped its wiring using electron microscopy.
nature.com/immersive/d42859-025-00001-w/index.html
The MICrONS Project
An unprecedented dataset of high resolution anatomical images of individual cells in mouse visual cortex, mapped on to their responses. This integrated view of function and structure lays a foundation...
nature.com
April 11, 2025 at 12:01 AM
I 💙 seeing team science makin it happen
Reposted by Jonna Singh
www.nytimes.com/2025/04/03/o...
Really important piece to share widely. Too many Americans don’t know how severe a threat this Administration poses to our scientific infrastructure, global leadership, and health security
Really important piece to share widely. Too many Americans don’t know how severe a threat this Administration poses to our scientific infrastructure, global leadership, and health security
Opinion | The Uncertain Fate of the Young American Scientist (Gift Article)
Young researchers are choosing between staying in science and staying in the United States.
www.nytimes.com
April 4, 2025 at 7:32 AM
www.nytimes.com/2025/04/03/o...
Really important piece to share widely. Too many Americans don’t know how severe a threat this Administration poses to our scientific infrastructure, global leadership, and health security
Really important piece to share widely. Too many Americans don’t know how severe a threat this Administration poses to our scientific infrastructure, global leadership, and health security
Reposted by Jonna Singh
BREAKING: We're suing the National Institutes of Health over their politically-motivated purge of research grants.
This is an unlawful attack on scientific progress that puts lives at risk.
This is an unlawful attack on scientific progress that puts lives at risk.
April 2, 2025 at 8:03 PM
BREAKING: We're suing the National Institutes of Health over their politically-motivated purge of research grants.
This is an unlawful attack on scientific progress that puts lives at risk.
This is an unlawful attack on scientific progress that puts lives at risk.