Johannes Zuber
@johanneszuber.bsky.social
Senior Group Leader IMP / Adjunct Professor Medical University of Vienna. Fascinated by functional genetics (CRISPR, RNAi, degrons) and time-resolved omics towards understanding cancer biology and probing new therapeutic concepts.
Pinned
🌍Open call: Junior Group Leader positions!
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Become our colleague! Apply for Junior Group Leader positions at @impvienna.bsky.social!
Become our colleague! Apply for Junior Group Leader positions at @impvienna.bsky.social!
🌍Open call: Junior Group Leader positions!
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
November 10, 2025 at 10:22 PM
Become our colleague! Apply for Junior Group Leader positions at @impvienna.bsky.social!
Reposted by Johannes Zuber
Read more about Paul's project here: imp.ac.at/news/article...
And more about Robert's thesis here: imp.ac.at/news/article...
@vbcscitraining.bsky.social, @viennabiocenter.bsky.social, @johanneszuber.bsky.social, @fbzt.bsky.social
And more about Robert's thesis here: imp.ac.at/news/article...
@vbcscitraining.bsky.social, @viennabiocenter.bsky.social, @johanneszuber.bsky.social, @fbzt.bsky.social
November 7, 2025 at 5:20 PM
Read more about Paul's project here: imp.ac.at/news/article...
And more about Robert's thesis here: imp.ac.at/news/article...
@vbcscitraining.bsky.social, @viennabiocenter.bsky.social, @johanneszuber.bsky.social, @fbzt.bsky.social
And more about Robert's thesis here: imp.ac.at/news/article...
@vbcscitraining.bsky.social, @viennabiocenter.bsky.social, @johanneszuber.bsky.social, @fbzt.bsky.social
Reposted by Johannes Zuber
🧵1/17
📣Thrilled to share our latest study just out in Cancer Discovery!
➡️
aacrjournals.org/cancerdiscov...
📣Thrilled to share our latest study just out in Cancer Discovery!
➡️
aacrjournals.org/cancerdiscov...
A plastic EMP1⁺ to LGR5⁺ cell state conversion as a bypass to KRAS-G12D pharmacological inhibition in metastatic colorectal cancer
Abstract. Inhibitors of the oncogene KRAS hold promise for treating metastatic CRC (mCRC). Here we show that a selective, covalent small molecule inhibitor of the active (ON) conformation of RAS-G12D,...
aacrjournals.org
October 23, 2025 at 6:07 PM
🧵1/17
📣Thrilled to share our latest study just out in Cancer Discovery!
➡️
aacrjournals.org/cancerdiscov...
📣Thrilled to share our latest study just out in Cancer Discovery!
➡️
aacrjournals.org/cancerdiscov...
Just out in @science.org: Together with the lab of @wilhelmpalm.bsky.social, we used sequential in-vitro/in-vivo CRISPR screens to decipher metabolic adaptations in tumors. We find that acidosis is a dominant factor that shapes energy metabolism and stress resilience. www.science.org/doi/10.1126/...
October 9, 2025 at 7:37 PM
Just out in @science.org: Together with the lab of @wilhelmpalm.bsky.social, we used sequential in-vitro/in-vivo CRISPR screens to decipher metabolic adaptations in tumors. We find that acidosis is a dominant factor that shapes energy metabolism and stress resilience. www.science.org/doi/10.1126/...
Reposted by Johannes Zuber
📢Open call: the International Birnstiel Award for Doctoral Research in Molecular Life Sciences is now accepting nominations!
Do you know an outstanding PhD student who deserves recognition?
Nominate them by 30 June 👉 www.imp.ac.at/achievements...
🎥 www.youtube.com/watch?v=ghfQ...
Do you know an outstanding PhD student who deserves recognition?
Nominate them by 30 June 👉 www.imp.ac.at/achievements...
🎥 www.youtube.com/watch?v=ghfQ...
International Birnstiel Award for Doctoral Research in Molecular Life Sciences
YouTube video by Research Institute of Molecular Pathology
www.youtube.com
May 8, 2025 at 7:51 AM
📢Open call: the International Birnstiel Award for Doctoral Research in Molecular Life Sciences is now accepting nominations!
Do you know an outstanding PhD student who deserves recognition?
Nominate them by 30 June 👉 www.imp.ac.at/achievements...
🎥 www.youtube.com/watch?v=ghfQ...
Do you know an outstanding PhD student who deserves recognition?
Nominate them by 30 June 👉 www.imp.ac.at/achievements...
🎥 www.youtube.com/watch?v=ghfQ...
Reposted by Johannes Zuber
Here's a first collection of great life science institutes worldwide you can follow to help you get back in the loop. 🌍🔬
Did we miss any? Let us know, and we'll add them!
go.bsky.app/A5Jrf8N
Did we miss any? Let us know, and we'll add them!
go.bsky.app/A5Jrf8N
February 4, 2025 at 8:25 AM
Here's a first collection of great life science institutes worldwide you can follow to help you get back in the loop. 🌍🔬
Did we miss any? Let us know, and we'll add them!
go.bsky.app/A5Jrf8N
Did we miss any? Let us know, and we'll add them!
go.bsky.app/A5Jrf8N
Are you a #Masters student interested in translational
#cancer research, tumor immunology and #CRISPR screens? Then apply to our lab at the @impvienna.bsky.social in Vienna:
www.imp.ac.at/career/open-...
#oncology, #cancerresearch, #CRISPR
#cancer research, tumor immunology and #CRISPR screens? Then apply to our lab at the @impvienna.bsky.social in Vienna:
www.imp.ac.at/career/open-...
#oncology, #cancerresearch, #CRISPR
January 7, 2025 at 6:50 PM
Are you a #Masters student interested in translational
#cancer research, tumor immunology and #CRISPR screens? Then apply to our lab at the @impvienna.bsky.social in Vienna:
www.imp.ac.at/career/open-...
#oncology, #cancerresearch, #CRISPR
#cancer research, tumor immunology and #CRISPR screens? Then apply to our lab at the @impvienna.bsky.social in Vienna:
www.imp.ac.at/career/open-...
#oncology, #cancerresearch, #CRISPR
Another masterpiece from our friends in the Obenauf lab, deciphering an entire cascade that enables cancer cells to evade immunity & discovering a key role of monocytes in T-cell activation! Huge congrats to @obenaufa.bsky.social, @aelewaut.bsky.social, @guillemxtivill.bsky.social & all co-authors!
1/23 Big news for the #ObenaufLab! So excited to finally share our new study providing another puzzle piece, why immunotherapy fails in many tumors, now out in @Nature 🧵👇 www.nature.com/articles/s41...
November 27, 2024 at 6:36 PM
Another masterpiece from our friends in the Obenauf lab, deciphering an entire cascade that enables cancer cells to evade immunity & discovering a key role of monocytes in T-cell activation! Huge congrats to @obenaufa.bsky.social, @aelewaut.bsky.social, @guillemxtivill.bsky.social & all co-authors!
Reposted by Johannes Zuber
Are you a #postdoc with an innovative vision for starting your own lab in #Syntheticbiology, #Genomics, #GeneRegulation, #Development, #Cancer, #Immunology or #InfectionBiology?
@IMPvienna is inviting applications for group leader positions: www.imp.ac.at/career/open-...
Pls share!
@IMPvienna is inviting applications for group leader positions: www.imp.ac.at/career/open-...
Pls share!
November 19, 2024 at 3:08 PM
Are you a #postdoc with an innovative vision for starting your own lab in #Syntheticbiology, #Genomics, #GeneRegulation, #Development, #Cancer, #Immunology or #InfectionBiology?
@IMPvienna is inviting applications for group leader positions: www.imp.ac.at/career/open-...
Pls share!
@IMPvienna is inviting applications for group leader positions: www.imp.ac.at/career/open-...
Pls share!