Joana Segura-Martinez
LightNews LightNews
joanasgrmrtnz.bsky.social
Joana Segura-Martinez
@joanasgrmrtnz.bsky.social
18 followers 13 following 5 posts
Posts Replies Media Videos
Reposted by Joana Segura-Martinez
acarreiralab.bsky.social
🚨 Exciting news! Our latest study is out in Nature Communications!
We reveal how specific BRCA2 mutations can hijack transcriptional programs—beyond their role in DNA repair.
🔗 rdcu.be/eT1R9
#CancerResearch #BRCA2 #Genomics
A recurrent pathogenic BRCA2 truncating variant reveals a role for BRCA2-PCAF complex in modulating NF-κB-driven transcription - Nature Communications
Pathogenic BRCA2 truncating variants in heterozygosis drive distinct cancer-linked mechanisms. Here the authors show that one causes PARPi sensitivity and HR loss via haploinsufficiency, while another...
www.nature.com
December 10, 2025 at 12:11 PM
Reposted by Joana Segura-Martinez
harry-brennan.bsky.social
⚗️🧪 Hoy tocó desayuno de celebración en el @genomefun.bsky.social y coincidió con el #DíaDelQuímico 🧬🧫
December 1, 2025 at 5:40 PM
Reposted by Joana Segura-Martinez
harry-brennan.bsky.social
🏵 ¡La celebración por el #DíaDeMuertos llegó al laboratorio de la Organización Funcional del Genoma de Mamíferos! 🧬
October 30, 2025 at 5:04 PM
Reposted by Joana Segura-Martinez
cbm-csic-uam.bsky.social
Mil gracias a Julia Otero y todo el equipo de @juliaenlaonda.bsky.social por contar a vuestra audiencia lo que hacemos en el CBM, lo que llevamos haciendo 50 años siguiendo la estela de Severo Ochoa. ¡Por otros cincuenta años más del CBM y de #JELO! @ondacero.es @csic.es @uam.es
November 1, 2025 at 11:45 AM
Reposted by Joana Segura-Martinez
genomefun.bsky.social
The @cbm-csic-uam.bsky.social has celebrated its Golden Jubilee with two days filled with inspiring talks. We had the joy of hearing from outstanding scientists — including Nobel Prize laureates and leading figures in molecular biology — we were truly honored to have spoken with Dr. Svante Pääbo
September 30, 2025 at 6:17 PM
Reposted by Joana Segura-Martinez
emlecona.bsky.social
We are looking for a candidate to apply to a #MSCA Postdoctoral Fellowship in our lab in the @CBM_CSIC_UAM, working on the connections between DNA replication dynamics, replication stress and genomic instability in cáncer. Contact us if you are interested and please retweet.
a cartoon of a coyote with binoculars and the words looney tunes on the bottom right
ALT: a cartoon of a coyote with binoculars and the words looney tunes on the bottom right
media.tenor.com
August 4, 2025 at 1:32 PM
joanasgrmrtnz.bsky.social
It's Science... 🧪
First human genome from ancient Egypt sequenced from 4,800-year-old teeth
Forty years after the first effort to extract mummy DNA, researchers have finally generated a full genome sequence from an ancient Egyptian.
www.nature.com
July 3, 2025 at 4:54 PM
joanasgrmrtnz.bsky.social
Congratulations to all 🎉
Terrific work 👇🏼
emlecona.bsky.social Emilio Lecona @emlecona.bsky.social · Jul 3
Very happy to share our recently published work on the role of VCP/p97 during DNA replication.
replifate.bsky.social Replifate Consortium @replifate.bsky.social · Jul 3
Just published!

Lecona (@emlecona.bsky.social ) & Méndez #RepliFate labs show that VCP/p97 removes Pol α/primase from chromatin to avoid excess ATR activation during normal #DNAreplication

VCP/p97 = checkpoint gatekeeper!

Read the full study: doi.org/10.1038/s414...
July 3, 2025 at 1:53 PM
Reposted by Joana Segura-Martinez
cbm-csic-uam.bsky.social
¿Te interesa el cruce entre arte y ciencia? Este viernes 4 de julio a las 12:00, ven a la charla de la artista residente RepliFate Helen Pynor y a la mesa redonda con científic@s del CBM y CNIO.
📍 Evento en inglés con subtítulos en vivo en español
🎟️ Entrada libre
¡Te esperamos!
June 30, 2025 at 2:55 PM
Reposted by Joana Segura-Martinez
cbm-csic-uam.bsky.social
¡ #arteyciencia en el CBM! Durante dos semanas tenemos con nosotros a la artista autraliana Helen Pynor, como parte del programa "Artists in Residence" de la red doctoral europea RepliFate. Trabajará con Emilio Lecona y María Gomez, IPs de esta red en el CBM.

@csic.es @uam.es
June 25, 2025 at 12:35 PM
Reposted by Joana Segura-Martinez
cbm-csic-uam.bsky.social
La semana pasada recibimos en el CBM a 7 estudiantes del programa Científic@s en prácticas. Pasaron cinco días increíbles en los laboratorios de Miguel Manzanares, María Gómez y Natalia Azpiazu. ¡Gracias a l@s investigador@s por su generosidad y a l@s chic@s por su entusiasmo! 🥼
June 24, 2025 at 12:47 PM
joanasgrmrtnz.bsky.social
So grateful to have reconnected with my former boss and mentor — such an inspiring scientist and person. I hope we can stay in touch and maybe even do some science together again! 😊
genomefun.bsky.social Genome Function Lab @genomefun.bsky.social · Jun 6
Today we had the pleasure of hosting @aruizherrera.bsky.social at the @cbm-csic-uam.bsky.social !
She shared fascinating insights into chromatin organization across evolution and cell types, sparking engaging discussions and fresh ideas.
We look forward to seeing you again soon! Thank you!
June 8, 2025 at 6:52 AM