Josef
@jmelcr.bsky.social
Scientist, startup founder, dad, writer, bass player, photographer, philosopher and board game geek. Can be really charming on a nice day.
When I first looked at the figure in the attached paper, I first thought it depicts a brain, huh!
For decades, how methanogenic archaea activate the MCR complex to produce methane remained a mystery. Today in Nature, we report the high-resolution cryo-EM structure of the MCR activation complex!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Structure of the ATP-driven methyl-coenzyme M reductase activation complex - Nature
The structure and function of the MCR activation complex from Methanococcus maripaludis were revealed, demonstrating its ATP-dependent ability to activate MCR and form methane while uncovering a uniqu...
www.nature.com
April 16, 2025 at 5:50 PM
When I first looked at the figure in the attached paper, I first thought it depicts a brain, huh!
Reposted by Josef
I'm so used to bar bathrooms with cutesy signs that I had to stop here and ask myself if I was a Mario or a Wario
April 13, 2025 at 3:33 AM
I'm so used to bar bathrooms with cutesy signs that I had to stop here and ask myself if I was a Mario or a Wario
I wonder what adventure Indiana Jones would do in 2025. And where.
We know that Indiana Jones lives into the 1990s.
In 1977, do you think he went to a movie theater to watch “Star Wars”?
In 1977, do you think he went to a movie theater to watch “Star Wars”?
March 30, 2025 at 6:41 AM
I wonder what adventure Indiana Jones would do in 2025. And where.
Shocking.
Imagine any other world leader saying this about another country.
March 30, 2025 at 6:33 AM
Shocking.
Lessons from history - interesting read on medium
medium.com/lessons-from...
medium.com/lessons-from...
A 1939 Nazi Rally in New York Revealed How Hateful Religious Views Fueled Racism
The rally’s speakers mixed American pride with religious talk to back racist ideas.
medium.com
March 29, 2025 at 3:54 PM
Lessons from history - interesting read on medium
medium.com/lessons-from...
medium.com/lessons-from...
🤭
March 29, 2025 at 8:40 AM
🤭
Reposted by Josef
Time is the only currency you spend without ever knowing your balance.
Use it wisely.
Use it wisely.
March 16, 2025 at 4:04 AM
Time is the only currency you spend without ever knowing your balance.
Use it wisely.
Use it wisely.
History keeps repeating itself, only its means while with technology. Once it was governance over press, nowadays over AI.
March 16, 2025 at 7:51 PM
History keeps repeating itself, only its means while with technology. Once it was governance over press, nowadays over AI.
Been there! 🤣
Oh no. While cooking the meal I have accidentally eaten 2/3s of the grated cheese. And it was so incremental I don’t even feel like I have eaten cheese
March 16, 2025 at 6:02 PM
Been there! 🤣
Some consider #StarWars as just a frivolous fiction space opera. But I find it hard to resist the feeling that our world has never been closer to the plot as an allegory to #society. Political and economical #power stand against #struggle for #freedom.
#Rebels and #Jedi needed!
#Rebels and #Jedi needed!
March 16, 2025 at 6:00 PM
March 1, 2025 at 2:24 PM
I read news and I'm disgusted.
March 1, 2025 at 10:35 AM
I read news and I'm disgusted.
It takes courage to choose kindness, especially when you feel you've been wronged. It's worth it.
Kindness helped me in disarming and angry violent person I encountered recently. I chose kindness despite I was the victim of their verbal attacks. #proudofmyself #resolve #conflict #in #peace
Kindness helped me in disarming and angry violent person I encountered recently. I chose kindness despite I was the victim of their verbal attacks. #proudofmyself #resolve #conflict #in #peace
February 23, 2025 at 7:14 AM
It takes courage to choose kindness, especially when you feel you've been wronged. It's worth it.
Kindness helped me in disarming and angry violent person I encountered recently. I chose kindness despite I was the victim of their verbal attacks. #proudofmyself #resolve #conflict #in #peace
Kindness helped me in disarming and angry violent person I encountered recently. I chose kindness despite I was the victim of their verbal attacks. #proudofmyself #resolve #conflict #in #peace
You're the only one who can truly give you everything. You are your greatest asset. #Believeinyourself #motivation #positive #thinking
February 22, 2025 at 2:05 PM
You're the only one who can truly give you everything. You are your greatest asset. #Believeinyourself #motivation #positive #thinking
Reposted by Josef
Worst. Episode. EVER.
February 22, 2025 at 4:00 AM
Worst. Episode. EVER.
Reposted by Josef
Yeah, it's his perpetually healing blood. But kids can't drink it.
February 4, 2025 at 3:37 AM
Yeah, it's his perpetually healing blood. But kids can't drink it.
Reposted by Josef
January 4, 2025 at 4:20 PM
I like to flip these pictures around to get an interesting new perspective.
This one looks so well upside down!
This one looks so well upside down!
December 29, 2024 at 4:31 PM
I like to flip these pictures around to get an interesting new perspective.
This one looks so well upside down!
This one looks so well upside down!
Compared to animals, people have an extra weapon - reason, a double-edged sword that can be used for both good as well as .. not so good.
Yet we are always free to choose how to wield it.
#philosophy #reason #life #positive #thinking
Yet we are always free to choose how to wield it.
#philosophy #reason #life #positive #thinking
True statement that often makes me feel terribly sad ashamed of the world we live in. 😪🙏
December 29, 2024 at 4:19 PM
Compared to animals, people have an extra weapon - reason, a double-edged sword that can be used for both good as well as .. not so good.
Yet we are always free to choose how to wield it.
#philosophy #reason #life #positive #thinking
Yet we are always free to choose how to wield it.
#philosophy #reason #life #positive #thinking
Reposted by Josef
A passage from the Tao that’s frequently worth revisiting.
December 27, 2024 at 10:15 PM
A passage from the Tao that’s frequently worth revisiting.
Long journey to improve Martini lipids coming to its close. Glad to be part of it at the very beginning.
Excited to announce the release of our preprint, "The Martini 3 Lipidome: Expanded and Refined Parameters Improve Lipid Phase Behavior", now available on @chemrxiv.bsky.social
👉 Read the full preprint here: chemrxiv.org/engage/chemr...
👉 Read the full preprint here: chemrxiv.org/engage/chemr...
December 26, 2024 at 6:27 PM
Long journey to improve Martini lipids coming to its close. Glad to be part of it at the very beginning.