Jess Moore
@jlmoore.bsky.social
Schmidt Science Fellow, Cagla Eroglu’s lab @ Duke
Studying astrocyte endfeet ⭐️
PhD from Valentina Greco’s lab @ Yale
Studying astrocyte endfeet ⭐️
PhD from Valentina Greco’s lab @ Yale
Reposted by Jess Moore
Finally it’s here! 🌟⬇️
www.nature.com/articles/s41...
I’m sooo excited to share our latest article led by Steve Hill and Isabel Bravo-Ferrer
1- How does the vasculature communicate with astrocytes?
2- Is this communication dependent to what happens in the body.
3- Is it relevant to human diseases?
www.nature.com/articles/s41...
I’m sooo excited to share our latest article led by Steve Hill and Isabel Bravo-Ferrer
1- How does the vasculature communicate with astrocytes?
2- Is this communication dependent to what happens in the body.
3- Is it relevant to human diseases?
Fig. 1: Establishment of methods to identify astrocyte endfoot proteins. | Nature Communications
www.nature.com
November 6, 2025 at 11:26 AM
Finally it’s here! 🌟⬇️
www.nature.com/articles/s41...
I’m sooo excited to share our latest article led by Steve Hill and Isabel Bravo-Ferrer
1- How does the vasculature communicate with astrocytes?
2- Is this communication dependent to what happens in the body.
3- Is it relevant to human diseases?
www.nature.com/articles/s41...
I’m sooo excited to share our latest article led by Steve Hill and Isabel Bravo-Ferrer
1- How does the vasculature communicate with astrocytes?
2- Is this communication dependent to what happens in the body.
3- Is it relevant to human diseases?
Reposted by Jess Moore
What cell states are possible when they are missing key factors - Nanog, Pou5f3 (Oct4), & Sox19b (Sox2) - that are required for the first embryonic reprogramming steps? Follow along with our latest publication, finally out at doi.org/10.1016/j.ce... #devbio #reprogramming #zebrafish #embryo (1/6)
November 3, 2025 at 6:09 PM
What cell states are possible when they are missing key factors - Nanog, Pou5f3 (Oct4), & Sox19b (Sox2) - that are required for the first embryonic reprogramming steps? Follow along with our latest publication, finally out at doi.org/10.1016/j.ce... #devbio #reprogramming #zebrafish #embryo (1/6)
Reposted by Jess Moore
@joann-trejo.bsky.social, @marymunson4.bsky.social and I have a commentary in @natcellbio.nature.com on recent attacks on DEI in biomedical research: "If scientific research, especially biomedical research, is meant to serve everyone, then it requires that everyone has an opportunity to participate"
Scaling back DEI programmes and the loss of scientific talent
Nature Cell Biology - Programmes that support diversity, equity and inclusion (DEI) in science are under attack in the USA. Data indicate that diversity in the scientific workforce increases...
www.nature.com
October 23, 2025 at 4:36 PM
@joann-trejo.bsky.social, @marymunson4.bsky.social and I have a commentary in @natcellbio.nature.com on recent attacks on DEI in biomedical research: "If scientific research, especially biomedical research, is meant to serve everyone, then it requires that everyone has an opportunity to participate"
Reposted by Jess Moore
My colleague @sarahhird.bsky.social has been fighting for family care leave for over a year now. So impressed with her leadership!
ctmirror.org/2025/10/21/t...
ctmirror.org/2025/10/21/t...
Opinion: This is UConn: Zero paid family leave for professors
UConn currently lets every pregnant/expecting individual reinvent the wheel, cobbling together a leave plan with whatever resources and departmental grace they can muster.
ctmirror.org
October 21, 2025 at 12:15 PM
My colleague @sarahhird.bsky.social has been fighting for family care leave for over a year now. So impressed with her leadership!
ctmirror.org/2025/10/21/t...
ctmirror.org/2025/10/21/t...
Reposted by Jess Moore
When Macrophages Disappear, Skin Blood Vessels Age!
Check out our new study @nature.com that uncovers how the loss of capillary-associated macrophages with age blocks vessel repair and blood flow, revealing a new cellular trigger of tissue aging. #Aging #Immunology
👇👇
www.nature.com/articles/s41...
Check out our new study @nature.com that uncovers how the loss of capillary-associated macrophages with age blocks vessel repair and blood flow, revealing a new cellular trigger of tissue aging. #Aging #Immunology
👇👇
www.nature.com/articles/s41...
Niche-specific dermal macrophage loss promotes skin capillary ageing - Nature
Capillary-associated macrophages are selectively lost over time, contributing to impaired vascular repair and reduced tissue perfusion in older mice.
www.nature.com
October 15, 2025 at 3:52 PM
When Macrophages Disappear, Skin Blood Vessels Age!
Check out our new study @nature.com that uncovers how the loss of capillary-associated macrophages with age blocks vessel repair and blood flow, revealing a new cellular trigger of tissue aging. #Aging #Immunology
👇👇
www.nature.com/articles/s41...
Check out our new study @nature.com that uncovers how the loss of capillary-associated macrophages with age blocks vessel repair and blood flow, revealing a new cellular trigger of tissue aging. #Aging #Immunology
👇👇
www.nature.com/articles/s41...
Reposted by Jess Moore
Interested in the heterogeneity of blood vessels in the CNS? Here we review the unique features of the spinal cord vasculature, its barrier properties and neurovascular interactions, highlighting unknown aspects and future research directions.
@CRC1366
@erc.europa.eu @immunosens.bsky.social
@CRC1366
@erc.europa.eu @immunosens.bsky.social
October 14, 2025 at 5:16 PM
Interested in the heterogeneity of blood vessels in the CNS? Here we review the unique features of the spinal cord vasculature, its barrier properties and neurovascular interactions, highlighting unknown aspects and future research directions.
@CRC1366
@erc.europa.eu @immunosens.bsky.social
@CRC1366
@erc.europa.eu @immunosens.bsky.social
Reposted by Jess Moore
Ho, @stephgupton.bsky.social et al. find that coronin 1A mediates neuronal growth cone & filopodial dynamics, & its interaction with E3 ubiquitin ligase TRIM67 is required for morphological responses to the guidance cue netrin-1 rupress.org/jcb/article/...
#Neuroscience #Cytoskeleton #Development
#Neuroscience #Cytoskeleton #Development
October 14, 2025 at 4:15 PM
Ho, @stephgupton.bsky.social et al. find that coronin 1A mediates neuronal growth cone & filopodial dynamics, & its interaction with E3 ubiquitin ligase TRIM67 is required for morphological responses to the guidance cue netrin-1 rupress.org/jcb/article/...
#Neuroscience #Cytoskeleton #Development
#Neuroscience #Cytoskeleton #Development
Reposted by Jess Moore
Consider donating to a hardworking non-profit that seeks to keep doors open into STEM higher ed and academia 🎓💜
www.cientificolatino.com/donate
www.cientificolatino.com/donate
Last year, we helped 100 students save $31K in grad school app fees, giving students from underserved communities the freedom to apply widely.
This year we lost 16 partners = $8.2K setback = 110 fewer dreams.
🎓 You can change that.
💸 Donate to open 110 new doors.
givebutter.com/supportCL
This year we lost 16 partners = $8.2K setback = 110 fewer dreams.
🎓 You can change that.
💸 Donate to open 110 new doors.
givebutter.com/supportCL
October 14, 2025 at 2:09 AM
Consider donating to a hardworking non-profit that seeks to keep doors open into STEM higher ed and academia 🎓💜
www.cientificolatino.com/donate
www.cientificolatino.com/donate
Reposted by Jess Moore
I am thrilled to share our latest story led by the incredibly talented Brooke D’Arcy and Camila Musso. We discover a rich world of local gene expression in radial glia, essential neural and glial precursors, and develop a new method for sub-cellular mRNA manipulation. www.biorxiv.org/content/10.1...
October 10, 2025 at 10:28 PM
I am thrilled to share our latest story led by the incredibly talented Brooke D’Arcy and Camila Musso. We discover a rich world of local gene expression in radial glia, essential neural and glial precursors, and develop a new method for sub-cellular mRNA manipulation. www.biorxiv.org/content/10.1...
Reposted by Jess Moore
So excited to announce lab alumni Dr. Helen Mengze He and Liana Boraas work at @yalecvrc.bsky.social in collaboration with the Kaelyn Sumigray lab @yaleschoolofmed.bsky.social is published today in @natcomms.nature.com and highlighted in Yale News! medicine.yale.edu/news-article...
Unlocking the Skin’s Natural Healing Power
Researchers show that embryonic skin stem cells rely on a specialized mechanism to resist injury. The findings could lead to new strategies for repairing wounds
medicine.yale.edu
October 10, 2025 at 3:39 PM
So excited to announce lab alumni Dr. Helen Mengze He and Liana Boraas work at @yalecvrc.bsky.social in collaboration with the Kaelyn Sumigray lab @yaleschoolofmed.bsky.social is published today in @natcomms.nature.com and highlighted in Yale News! medicine.yale.edu/news-article...
Reposted by Jess Moore
I am really glad that @jeremymberg.bsky.social wrote this. Everybody who cares about science, and about knowledge generation and civil society generally, should read and share with their favorite administrator.
Deafening Quiet from the Scientific Establishment
open.substack.com/pub/donmoyni...
Deafening Quiet from the Scientific Establishment
open.substack.com/pub/donmoyni...
Deafening Quiet from the Scientific Establishment
Leaders are underestimating the risks of not fighting back
open.substack.com
October 9, 2025 at 1:31 PM
I am really glad that @jeremymberg.bsky.social wrote this. Everybody who cares about science, and about knowledge generation and civil society generally, should read and share with their favorite administrator.
Deafening Quiet from the Scientific Establishment
open.substack.com/pub/donmoyni...
Deafening Quiet from the Scientific Establishment
open.substack.com/pub/donmoyni...
Reposted by Jess Moore
Goebbels Ends Careers of Five 'Aryan' Actors Who Made Witticisms About the Nazi Regime (Published 1939)
www.nytimes.com
September 18, 2025 at 3:15 PM
Reposted by Jess Moore
It's been a while since I applied to the #NSFGRFP... but over that time I developed this guide based on my experiences and mentoring other students with the NSF-GRFP through Cientifico Latino, Inc. (and otherwise)! 💛
Thank you to John Lê for the additional contributions!!
Thank you to John Lê for the additional contributions!!
Applying to the NSF-GRFP (or another fellowship) on a tight deadline?
We built a 7-week guide + timeline to get you from draft to submission. It’s not too late — you’ve got this! ✨
🔗 cientificolatino.com/apply-in-7-weeks
#NSFGRFP #GradSchool #Fellowship
We built a 7-week guide + timeline to get you from draft to submission. It’s not too late — you’ve got this! ✨
🔗 cientificolatino.com/apply-in-7-weeks
#NSFGRFP #GradSchool #Fellowship
September 9, 2025 at 4:22 PM
It's been a while since I applied to the #NSFGRFP... but over that time I developed this guide based on my experiences and mentoring other students with the NSF-GRFP through Cientifico Latino, Inc. (and otherwise)! 💛
Thank you to John Lê for the additional contributions!!
Thank you to John Lê for the additional contributions!!
Reposted by Jess Moore
Rodriguez Salazar, @caglaeroglu.bsky.social et al. @dukehealth.bsky.social show that Drp1-mediated mitochondrial fission is necessary for peripheral #astrocyte process formation. Loss of Drp1 induces astrocyte reactivity & disrupts cortical astrocyte organization rupress.org/jcb/article/...
September 3, 2025 at 6:30 PM
Rodriguez Salazar, @caglaeroglu.bsky.social et al. @dukehealth.bsky.social show that Drp1-mediated mitochondrial fission is necessary for peripheral #astrocyte process formation. Loss of Drp1 induces astrocyte reactivity & disrupts cortical astrocyte organization rupress.org/jcb/article/...
Reposted by Jess Moore
1/ Thrilled to share that my PhD thesis work is now out in its final form @nature.com! A huge thanks to the entire team (which has only grown since we first put this out), our peer reviewers, the Nature editorial team, and the incredible @arimolofskylab.bsky.social.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Dynamic fibroblast–immune interactions shape recovery after brain injury - Nature
Spatial transcriptomic studies and lineage tracing reveal that, after brain injury, transient profibrotic fibroblasts develop from existing brain fibroblasts, infiltrate lesions, regulate the local im...
www.nature.com
September 3, 2025 at 4:43 PM
1/ Thrilled to share that my PhD thesis work is now out in its final form @nature.com! A huge thanks to the entire team (which has only grown since we first put this out), our peer reviewers, the Nature editorial team, and the incredible @arimolofskylab.bsky.social.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Jess Moore
Calling all @apsphysiology.bsky.social members: let’s help raise some money to support ABRCMS student presentation awards! Goal is $1200/discipline to support 12 awards by Sept 30th! 🧪 abrcms.org/donate/stude...
ABRCMS Fundraising - Student Presentation Awards - ABRCMS
Judges – Help Us Raise Funds for Student Presentation Awards Thank you for your service as a judge at ABRCMS. Your dedication has helped shape the future of countless student scientists, and we’re dee...
abrcms.org
August 21, 2025 at 2:15 AM
Calling all @apsphysiology.bsky.social members: let’s help raise some money to support ABRCMS student presentation awards! Goal is $1200/discipline to support 12 awards by Sept 30th! 🧪 abrcms.org/donate/stude...
Reposted by Jess Moore
The White House budget proposal includes an $18B cut to NIH research funding in FY26. Explore the anticipated economic impacts in communities nationwide & click on any district to learn more and get a shareable scorecard.
New from our #SCIMaP team: scienceimpacts.org/fy26
New from our #SCIMaP team: scienceimpacts.org/fy26
SCIMaP - Impacts of Federal Cuts to Science and Medical Research
View Projected Impact of the FY2026 Budget Cuts to the NIH
scienceimpacts.org
August 15, 2025 at 2:53 PM
The White House budget proposal includes an $18B cut to NIH research funding in FY26. Explore the anticipated economic impacts in communities nationwide & click on any district to learn more and get a shareable scorecard.
New from our #SCIMaP team: scienceimpacts.org/fy26
New from our #SCIMaP team: scienceimpacts.org/fy26
Reposted by Jess Moore
Congratulations 2025 Gilliam Fellows and Advisors! 🎉
The Gilliam Fellows Program launches promising PhD students into impactful scientific research careers while fostering inclusive training environments.
Through this program, HHMI supports both graduate students and their faculty thesis advisors.
The Gilliam Fellows Program launches promising PhD students into impactful scientific research careers while fostering inclusive training environments.
Through this program, HHMI supports both graduate students and their faculty thesis advisors.
August 7, 2025 at 1:05 PM
Congratulations 2025 Gilliam Fellows and Advisors! 🎉
The Gilliam Fellows Program launches promising PhD students into impactful scientific research careers while fostering inclusive training environments.
Through this program, HHMI supports both graduate students and their faculty thesis advisors.
The Gilliam Fellows Program launches promising PhD students into impactful scientific research careers while fostering inclusive training environments.
Through this program, HHMI supports both graduate students and their faculty thesis advisors.
Reposted by Jess Moore
Thanks to @thetransmitter.bsky.social and @ldattaro.bsky.social for this coverage of our recent paper!
Some neurons respond more strongly to visual stimuli than others. But the rest of the brain doesn’t prioritize signals from those neurons, according to a new study. Read more in this month’s Null and Noteworthy.
By @ldattaro.bsky.social
#neuroskyence
www.thetransmitter.org/null-and-not...
By @ldattaro.bsky.social
#neuroskyence
www.thetransmitter.org/null-and-not...
Null and Noteworthy: Downstream brain areas read visual cortex signals en masse in mice
The finding contradicts a theory that the regions prioritize neurons that are adept at identifying specific stimuli. Plus, a response to a study that questioned immune memory in astrocytes.
www.thetransmitter.org
August 1, 2025 at 1:56 AM
Thanks to @thetransmitter.bsky.social and @ldattaro.bsky.social for this coverage of our recent paper!
Reposted by Jess Moore
Birth defects kill twice as many children as cancer. Animal model are crucial; no stem-cell or computer models can yet recapitulate the embryo's complexity. If you support birth defects research tell NIH that animal models are important! Click & scroll below to comment.
tinyurl.com/mr3he6bx
tinyurl.com/mr3he6bx
FDA-NIH Workshop: Reducing Animal Testing
The FDA is hosting a workshop on reducing animal testing. The workshop is open to current FDA and NIH employees.
tinyurl.com
July 11, 2025 at 5:22 PM
Birth defects kill twice as many children as cancer. Animal model are crucial; no stem-cell or computer models can yet recapitulate the embryo's complexity. If you support birth defects research tell NIH that animal models are important! Click & scroll below to comment.
tinyurl.com/mr3he6bx
tinyurl.com/mr3he6bx
Reposted by Jess Moore
This is so wrong-headed. You could not pay me to take a drug that was not tested in animals, and animal models remain absolutely essential for discovery research www.statnews.com/2025/05/19/a...
July 8, 2025 at 12:41 AM
This is so wrong-headed. You could not pay me to take a drug that was not tested in animals, and animal models remain absolutely essential for discovery research www.statnews.com/2025/05/19/a...
Reposted by Jess Moore
Happy to see the article I wrote in print back home! Thankful for the McClintock Letters organizers (@cornellasap.bsky.social) and Science Homecoming (@sciencehomecoming.bsky.social) for all their hard work in coordinating this effort.
Science Funding Cuts Affect Our Present and Future
Zebrafish are cool. They’re just one of a handful of animals that can regenerate their brain, spine, and even heart after injury. Unsurprisingly, a lot can be learned from studying how these injured o...
www.theintelligencer.net
June 14, 2025 at 11:07 AM
Happy to see the article I wrote in print back home! Thankful for the McClintock Letters organizers (@cornellasap.bsky.social) and Science Homecoming (@sciencehomecoming.bsky.social) for all their hard work in coordinating this effort.
Reposted by Jess Moore
No Kings march in Durham, NC. Easily the largest protest I've been to in Durham. Thousands ahead and behind me on the street /1
June 14, 2025 at 6:41 PM
No Kings march in Durham, NC. Easily the largest protest I've been to in Durham. Thousands ahead and behind me on the street /1
Reposted by Jess Moore
"We are speaking on behalf of hundreds of NIH staff who are standing up together to say: WE DISSENT.
I am so scared about doing this but I am trying to be brave for my kids because it's only gonna get harder to speak up."
Thank you to Dr. Jenna Norton and NIH scientists for your courage!
I am so scared about doing this but I am trying to be brave for my kids because it's only gonna get harder to speak up."
Thank you to Dr. Jenna Norton and NIH scientists for your courage!
June 9, 2025 at 5:25 PM
"We are speaking on behalf of hundreds of NIH staff who are standing up together to say: WE DISSENT.
I am so scared about doing this but I am trying to be brave for my kids because it's only gonna get harder to speak up."
Thank you to Dr. Jenna Norton and NIH scientists for your courage!
I am so scared about doing this but I am trying to be brave for my kids because it's only gonna get harder to speak up."
Thank you to Dr. Jenna Norton and NIH scientists for your courage!
Reposted by Jess Moore
We need your help! Support the next generation of STEM by becoming a #CLGSMI mentor 🩷
Learn more and apply here: cientificolatino.com/gsmi
Learn more and apply here: cientificolatino.com/gsmi
June 3, 2025 at 11:03 PM
We need your help! Support the next generation of STEM by becoming a #CLGSMI mentor 🩷
Learn more and apply here: cientificolatino.com/gsmi
Learn more and apply here: cientificolatino.com/gsmi