Jakob Reichmann
@jkbrmn.bsky.social
PostDoc at the Francis Crick Institute.
X-ray Imaging x Connectomics.
X-ray Imaging x Connectomics.
Reposted by Jakob Reichmann
#paper!
X-rays can resolve #ultrastructure in tissues non-destructively.
www.nature.com/articles/s41...
Shoutout to key collaborators at @crick.ac.uk and @psich.bsky.social Ana Diaz, @adrianawanner.bsky.social and @andreas-t-schaefer.bsky.social, and to the whole team that made this possible.
X-rays can resolve #ultrastructure in tissues non-destructively.
www.nature.com/articles/s41...
Shoutout to key collaborators at @crick.ac.uk and @psich.bsky.social Ana Diaz, @adrianawanner.bsky.social and @andreas-t-schaefer.bsky.social, and to the whole team that made this possible.
Nondestructive X-ray tomography of brain tissue ultrastructure - Nature Methods
Optimizations of X-ray nanotomography including the choice of resin allows high-resolution imaging of mouse brain tissue, approaching the resolution of volume electron microscopy. Since it does not re...
www.nature.com
November 27, 2025 at 11:51 AM
#paper!
X-rays can resolve #ultrastructure in tissues non-destructively.
www.nature.com/articles/s41...
Shoutout to key collaborators at @crick.ac.uk and @psich.bsky.social Ana Diaz, @adrianawanner.bsky.social and @andreas-t-schaefer.bsky.social, and to the whole team that made this possible.
X-rays can resolve #ultrastructure in tissues non-destructively.
www.nature.com/articles/s41...
Shoutout to key collaborators at @crick.ac.uk and @psich.bsky.social Ana Diaz, @adrianawanner.bsky.social and @andreas-t-schaefer.bsky.social, and to the whole team that made this possible.
Reposted by Jakob Reichmann
The Crick is an absolutely amazing place to work in - please share this opportunity widely with your colleagues and postdocs - and DM me if I can help in any way
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
October 9, 2025 at 3:00 PM
The Crick is an absolutely amazing place to work in - please share this opportunity widely with your colleagues and postdocs - and DM me if I can help in any way
Reposted by Jakob Reichmann
Join us *next Monday*!
#CrickXrays25
X-ray #nanoimaging of biological tissues
🇬🇧🌐 @crick.ac.uk & online
tinyurl.com/crickxrays25
Sponsored by @dectris.bsky.social, @webknossos.org and @biologists.bsky.social and backed by @brukercorporation.bsky.social and Histomography
#CrickXrays25
X-ray #nanoimaging of biological tissues
🇬🇧🌐 @crick.ac.uk & online
tinyurl.com/crickxrays25
Sponsored by @dectris.bsky.social, @webknossos.org and @biologists.bsky.social and backed by @brukercorporation.bsky.social and Histomography
October 7, 2025 at 9:20 AM
Join us *next Monday*!
#CrickXrays25
X-ray #nanoimaging of biological tissues
🇬🇧🌐 @crick.ac.uk & online
tinyurl.com/crickxrays25
Sponsored by @dectris.bsky.social, @webknossos.org and @biologists.bsky.social and backed by @brukercorporation.bsky.social and Histomography
#CrickXrays25
X-ray #nanoimaging of biological tissues
🇬🇧🌐 @crick.ac.uk & online
tinyurl.com/crickxrays25
Sponsored by @dectris.bsky.social, @webknossos.org and @biologists.bsky.social and backed by @brukercorporation.bsky.social and Histomography
In other news: our Brain Pathology paper is out! We used multiscale #XPCT on human FFPE brain to 3D-image Lewy & Hirano bodies, GvD, NFTs, and β-amyloid aggregates at subcellular resolution, quantifying electron density. doi.org/10.1111/bpa....
@uni-goettingen.de @esrf.fr
@uni-goettingen.de @esrf.fr
October 2, 2025 at 10:34 AM
In other news: our Brain Pathology paper is out! We used multiscale #XPCT on human FFPE brain to 3D-image Lewy & Hirano bodies, GvD, NFTs, and β-amyloid aggregates at subcellular resolution, quantifying electron density. doi.org/10.1111/bpa....
@uni-goettingen.de @esrf.fr
@uni-goettingen.de @esrf.fr
Excited to co-author work led by @karlokomorowski.bsky.social: multiscale XPCT of FFPE human heart-forming organoids at isotropic, subcellular resolution – 3D histology w/o sectioning or staining! 🫀 This opens the door for volumetric histology of complex organoid systems.
doi.org/10.1038/s420...
doi.org/10.1038/s420...
October 2, 2025 at 8:20 AM
Excited to co-author work led by @karlokomorowski.bsky.social: multiscale XPCT of FFPE human heart-forming organoids at isotropic, subcellular resolution – 3D histology w/o sectioning or staining! 🫀 This opens the door for volumetric histology of complex organoid systems.
doi.org/10.1038/s420...
doi.org/10.1038/s420...
Reposted by Jakob Reichmann
#Nanoimaging symposium @crick.ac.uk!
At #CrickXrays25 we'll tackle:
💫synchrotron upgrades
📈current limits in throughput, volume, resolution
🧪sample preparation for X-ray PC imaging
🧠♥️applications in neuroscience and tissue life science
🗓️13th October 2025
🇬🇧🌐 London & online
tinyurl.com/crickxrays25
At #CrickXrays25 we'll tackle:
💫synchrotron upgrades
📈current limits in throughput, volume, resolution
🧪sample preparation for X-ray PC imaging
🧠♥️applications in neuroscience and tissue life science
🗓️13th October 2025
🇬🇧🌐 London & online
tinyurl.com/crickxrays25
Hard X-ray imaging of biological soft tissues symposium 2025
tinyurl.com
September 23, 2025 at 10:43 AM
#Nanoimaging symposium @crick.ac.uk!
At #CrickXrays25 we'll tackle:
💫synchrotron upgrades
📈current limits in throughput, volume, resolution
🧪sample preparation for X-ray PC imaging
🧠♥️applications in neuroscience and tissue life science
🗓️13th October 2025
🇬🇧🌐 London & online
tinyurl.com/crickxrays25
At #CrickXrays25 we'll tackle:
💫synchrotron upgrades
📈current limits in throughput, volume, resolution
🧪sample preparation for X-ray PC imaging
🧠♥️applications in neuroscience and tissue life science
🗓️13th October 2025
🇬🇧🌐 London & online
tinyurl.com/crickxrays25
Reposted by Jakob Reichmann
Our pre-print is out!
Critical point drying of brain tissue for x-ray phase contrast imaging.
@apeart.bsky.social @yuxinzhang.bsky.social @jkbrmn.bsky.social @apacureanu.bsky.social @andreas-t-schaefer.bsky.social
@carlesbosch.bsky.social
@esrf.fr
@crick.ac.uk
bioarXiv: doi.org/10.1101/2025...
Critical point drying of brain tissue for x-ray phase contrast imaging.
@apeart.bsky.social @yuxinzhang.bsky.social @jkbrmn.bsky.social @apacureanu.bsky.social @andreas-t-schaefer.bsky.social
@carlesbosch.bsky.social
@esrf.fr
@crick.ac.uk
bioarXiv: doi.org/10.1101/2025...
Critical point drying of brain tissue for X-ray phase contrast imaging
X-ray phase contrast tomography is emerging as a powerful method for imaging large volumes of brain tissue at sub-cellular resolution. However, current sample preparation methods are largely inherited...
doi.org
September 10, 2025 at 3:19 PM
Our pre-print is out!
Critical point drying of brain tissue for x-ray phase contrast imaging.
@apeart.bsky.social @yuxinzhang.bsky.social @jkbrmn.bsky.social @apacureanu.bsky.social @andreas-t-schaefer.bsky.social
@carlesbosch.bsky.social
@esrf.fr
@crick.ac.uk
bioarXiv: doi.org/10.1101/2025...
Critical point drying of brain tissue for x-ray phase contrast imaging.
@apeart.bsky.social @yuxinzhang.bsky.social @jkbrmn.bsky.social @apacureanu.bsky.social @andreas-t-schaefer.bsky.social
@carlesbosch.bsky.social
@esrf.fr
@crick.ac.uk
bioarXiv: doi.org/10.1101/2025...
Thanks for featuring!
Examining the placenta in detail in 3D brings insights for preventing complications in pregnancy
📹 Jakob Reichmann et al, University of Göttingen, Germany in
@pnasnexus.org
➡️ bpod.org.uk/archive/2025... with
John Ankers
📹 Jakob Reichmann et al, University of Göttingen, Germany in
@pnasnexus.org
➡️ bpod.org.uk/archive/2025... with
John Ankers
May 26, 2025 at 11:50 AM
Thanks for featuring!
Reposted by Jakob Reichmann
My PhD project is out as a preprint!
We combined 2P and synchrotron X-ray to understand mouse olfactory bulb circuits, linking physiology to structure in 3 animals!
doi.org/10.1101/2025...
🙌 @carlesbosch.bsky.social, @apacureanu.bsky.social, @andreas-t-schaefer.bsky.social, @esrf.fr, @crick.ac.uk
We combined 2P and synchrotron X-ray to understand mouse olfactory bulb circuits, linking physiology to structure in 3 animals!
doi.org/10.1101/2025...
🙌 @carlesbosch.bsky.social, @apacureanu.bsky.social, @andreas-t-schaefer.bsky.social, @esrf.fr, @crick.ac.uk
May 1, 2025 at 12:20 PM
My PhD project is out as a preprint!
We combined 2P and synchrotron X-ray to understand mouse olfactory bulb circuits, linking physiology to structure in 3 animals!
doi.org/10.1101/2025...
🙌 @carlesbosch.bsky.social, @apacureanu.bsky.social, @andreas-t-schaefer.bsky.social, @esrf.fr, @crick.ac.uk
We combined 2P and synchrotron X-ray to understand mouse olfactory bulb circuits, linking physiology to structure in 3 animals!
doi.org/10.1101/2025...
🙌 @carlesbosch.bsky.social, @apacureanu.bsky.social, @andreas-t-schaefer.bsky.social, @esrf.fr, @crick.ac.uk
Reposted by Jakob Reichmann
Using cutting-edge visualization tools, researchers captured a high-resolution, three-dimensional view of the human placenta, an often-overlooked organ upon which every living human once depended. In PNAS Nexus: academic.oup.com/pnasnexus/ad...
January 16, 2025 at 8:01 PM
Using cutting-edge visualization tools, researchers captured a high-resolution, three-dimensional view of the human placenta, an often-overlooked organ upon which every living human once depended. In PNAS Nexus: academic.oup.com/pnasnexus/ad...