Jesse
@jesse.bpd.fyi
Independent researcher studying the endogenous opioid system in BPD & dissociative disorders.
Mechanism-based analysis bridging clinicians and patients.
bpd.fyi
they/them
Mechanism-based analysis bridging clinicians and patients.
bpd.fyi
they/them
Reposted by Jesse
the Black Panthers were right
February 15, 2026 at 5:47 PM
the Black Panthers were right
Dissociation is mediated in part by the endogenous opioid system
I explore the overlap with BPD and why slow, continuous transdermal buprenorphine may help a subset of patients
Also covers ultra-low-dose naltrexone in plural systems
bpd.fyi/did-and-bpd
#BPD #Dissociation #DID #OSDD #Psychiatry
I explore the overlap with BPD and why slow, continuous transdermal buprenorphine may help a subset of patients
Also covers ultra-low-dose naltrexone in plural systems
bpd.fyi/did-and-bpd
#BPD #Dissociation #DID #OSDD #Psychiatry
Why Transdermal Buprenorphine Might Help in DID and BPD
bpd.fyi is a patient-run resource for people with Borderline Personality Disorder exploring treatment options and self-advocacy. Documents lived experience with low-dose buprenorphine with research co...
bpd.fyi
February 16, 2026 at 4:01 PM
Dissociation is mediated in part by the endogenous opioid system
I explore the overlap with BPD and why slow, continuous transdermal buprenorphine may help a subset of patients
Also covers ultra-low-dose naltrexone in plural systems
bpd.fyi/did-and-bpd
#BPD #Dissociation #DID #OSDD #Psychiatry
I explore the overlap with BPD and why slow, continuous transdermal buprenorphine may help a subset of patients
Also covers ultra-low-dose naltrexone in plural systems
bpd.fyi/did-and-bpd
#BPD #Dissociation #DID #OSDD #Psychiatry
i owe some people replies. it's been a busy & chaotic month to say the least.
February 1, 2026 at 4:29 AM
i owe some people replies. it's been a busy & chaotic month to say the least.
Learned more than I ever expected about ERISA and how employer-sponsored insurance plans are actually enforced.
January 14, 2026 at 6:26 AM
Learned more than I ever expected about ERISA and how employer-sponsored insurance plans are actually enforced.
this is still somewhat true of what life looks like for me, but in the 2nd half of 2025 i did a lot more paid work, mostly programming, & it was really enjoyable for many reasons.
caregiving is pretty lonely. usually it's keeping me pretty busy with chores, finding new medical providers, arguing with insurance, fixing medicine problems. i don't usually have time for posting or talking with people really. i'm just exhausted.
January 6, 2026 at 4:32 PM
this is still somewhat true of what life looks like for me, but in the 2nd half of 2025 i did a lot more paid work, mostly programming, & it was really enjoyable for many reasons.
I put together a website about BPD & how low-dose buprenorphine helped me become more stable. The endogenous opioid dysregulation theory suggests that people with BPD may have lower baseline endogenous opioids & end up trying to self-regulate through intense behaviors.
bpd.fyi
bpd.fyi
bpd.fyi — Buprenorphine & BPD Resource
A clear, patient-centered overview of buprenorphine’s potential role in stabilizing BPD symptoms, with research citations and accessible explanations.
bpd.fyi
December 11, 2025 at 6:05 PM
I put together a website about BPD & how low-dose buprenorphine helped me become more stable. The endogenous opioid dysregulation theory suggests that people with BPD may have lower baseline endogenous opioids & end up trying to self-regulate through intense behaviors.
bpd.fyi
bpd.fyi
I finally feel better today after a month of feeling off & low energy.
November 26, 2025 at 8:51 PM
I finally feel better today after a month of feeling off & low energy.
today's plan
- quick sample drop off at the vet
- build a cabinet
- sit with Vera for an appointment
- make progress on my coding demo
- quick sample drop off at the vet
- build a cabinet
- sit with Vera for an appointment
- make progress on my coding demo
November 21, 2025 at 5:24 PM
today's plan
- quick sample drop off at the vet
- build a cabinet
- sit with Vera for an appointment
- make progress on my coding demo
- quick sample drop off at the vet
- build a cabinet
- sit with Vera for an appointment
- make progress on my coding demo
i'm capable of solving difficult problems
November 20, 2025 at 9:01 PM
i'm capable of solving difficult problems
I was thinking about why it seems like I'm all of a sudden able to and have more desire to talk with people again.
I got back on some medicine on November 1st, after being off it for a year and a half.
I got back on some medicine on November 1st, after being off it for a year and a half.
November 16, 2025 at 5:14 PM
I was thinking about why it seems like I'm all of a sudden able to and have more desire to talk with people again.
I got back on some medicine on November 1st, after being off it for a year and a half.
I got back on some medicine on November 1st, after being off it for a year and a half.
Here's a picture of my cats. They love each other.
November 14, 2025 at 4:15 PM
Here's a picture of my cats. They love each other.
Reposted by Jesse
nori's website is gone now, i would like to share this one part. they're good values, and i will try to carry them with me. you nailed it on all of them. i am proud to have been able to call you a friend
November 6, 2025 at 1:39 PM
nori's website is gone now, i would like to share this one part. they're good values, and i will try to carry them with me. you nailed it on all of them. i am proud to have been able to call you a friend
Reposted by Jesse
Poet, musician, and software engineer nori li, here as @nori.gay, has died. She was phenomenally talented and dearly loved
💜 🏳️⚧️ 💜
💜 🏳️⚧️ 💜
honoring the life of nori li
A celebration of nori li, an American poet, musician and software engineer, who was passionate about the arts and trans liberation.
honoringnori.gay
November 6, 2025 at 2:08 AM
Poet, musician, and software engineer nori li, here as @nori.gay, has died. She was phenomenally talented and dearly loved
💜 🏳️⚧️ 💜
💜 🏳️⚧️ 💜
I’ve been offline for a while. I miss being in quiet connection with people.
starting small again.
starting small again.
November 5, 2025 at 4:16 AM
I’ve been offline for a while. I miss being in quiet connection with people.
starting small again.
starting small again.
Reposted by Jesse
How do I explain to offline people that my favorite Japanese mascot said "we can only be liberated from queer oppression if we are truly seen as human" and then started wielding fireworks like a rocket launcher on the side of a mountain without sounding like I've totally lost it?
Chiitan forever
Chiitan forever
Chiitan has a dream.
I hope that one day the term LGBT will become a thing of the past.
I will continue to spread my message until we live in a world where everyone can love freely and is free from persecution and discrimination.
Until then, let's all support each other🤍
I hope that one day the term LGBT will become a thing of the past.
I will continue to spread my message until we live in a world where everyone can love freely and is free from persecution and discrimination.
Until then, let's all support each other🤍
October 9, 2025 at 7:18 PM
How do I explain to offline people that my favorite Japanese mascot said "we can only be liberated from queer oppression if we are truly seen as human" and then started wielding fireworks like a rocket launcher on the side of a mountain without sounding like I've totally lost it?
Chiitan forever
Chiitan forever
Reposted by Jesse
I urge companies to take funding contributors seriously, in ways that aren’t tied to projects and goals. Being a generalist in the compiler meant that often I wasn’t working towards a roadmap, but my contributions *always* paid off in the long term extensibility of the language.
September 5, 2025 at 1:14 PM
I urge companies to take funding contributors seriously, in ways that aren’t tied to projects and goals. Being a generalist in the compiler meant that often I wasn’t working towards a roadmap, but my contributions *always* paid off in the long term extensibility of the language.
first week at the new job & it's going well i think! it's a 3 month contract to work on a few contributions to DocC. all of my work is open source so hopefully i'll share a bit along the way.
July 31, 2025 at 3:32 PM
first week at the new job & it's going well i think! it's a 3 month contract to work on a few contributions to DocC. all of my work is open source so hopefully i'll share a bit along the way.
i think my new manager should put a meeting on my calendar with the name "HEY >:("
i opened my calendar _yesterday_ & saw i missed TWO meetings.
first: "hello!"
second: "HELLO! :)"
i opened my calendar _yesterday_ & saw i missed TWO meetings.
first: "hello!"
second: "HELLO! :)"
July 31, 2025 at 3:21 PM
i think my new manager should put a meeting on my calendar with the name "HEY >:("
i opened my calendar _yesterday_ & saw i missed TWO meetings.
first: "hello!"
second: "HELLO! :)"
i opened my calendar _yesterday_ & saw i missed TWO meetings.
first: "hello!"
second: "HELLO! :)"
i got the job i interviewed for & i start on monday. i'm genuinely so excited & grateful. 😌
July 23, 2025 at 3:39 PM
i got the job i interviewed for & i start on monday. i'm genuinely so excited & grateful. 😌
i got a chance to go to the park today & i had my celebration rice noodle ramen.
July 14, 2025 at 10:27 PM
i got a chance to go to the park today & i had my celebration rice noodle ramen.
i'm finally trying to introduce more foods after doing SCD since september 2023.
July 13, 2025 at 5:57 PM
i'm finally trying to introduce more foods after doing SCD since september 2023.
i have a technical interview tomorrow for the first time in several years & i'm really hoping it goes well.
July 13, 2025 at 3:02 PM
i have a technical interview tomorrow for the first time in several years & i'm really hoping it goes well.