Jack Wilkinson
@jdwilko.bsky.social
Centre for Biostatistics, Uni of Manchester. INSPECT-SR, a tool to identify problematic clinical trials. Research misconduct, fertility research. Own opinions.
Pinned
Jack Wilkinson
@jdwilko.bsky.social
· Sep 5
INSPECT-SR: a tool for assessing trustworthiness of randomised controlled trials
The integrity of evidence synthesis is threatened by problematic randomised controlled trials (RCTs). These are RCTs where there are serious concerns about the trustworthiness of the data or findings....
www.medrxiv.org
www.medrxiv.org/content/10.1...
INSPECT-SR: A tool for assessing trustworthiness of randomised controlled trials.
INSPECT-SR: A tool for assessing trustworthiness of randomised controlled trials.
Have increased capacity for this December INSPECT-SR online training workshop following a successful 1st event today. Book here: www.trybooking.com/uk/FKHV
Introduction to INSPECT-SR Training Workshop December
An introductory 2-hour online workshop will introduce participants to the INSPECT-SR tool for assessing trustworthiness of randomised controlled...
www.trybooking.com
November 6, 2025 at 5:55 PM
Have increased capacity for this December INSPECT-SR online training workshop following a successful 1st event today. Book here: www.trybooking.com/uk/FKHV
Reposted by Jack Wilkinson
We've got loads of resources here for people to get started and be convinced to try it: asapbio.org/about/why-pr...
Why Preprints? – ASAPbio
Discover how preprints accelerate scientific discovery, increase visibility of research, and enable rapid feedback while maintaining research quality standards.
asapbio.org
October 25, 2025 at 6:40 PM
We've got loads of resources here for people to get started and be convinced to try it: asapbio.org/about/why-pr...
Reposted by Jack Wilkinson
Happy to follow up individually if there's more info I can provide. See also our FAQs: asapbio.org/about/faq/pr...
Preprint FAQ – ASAPbio
asapbio.org
October 25, 2025 at 6:40 PM
Happy to follow up individually if there's more info I can provide. See also our FAQs: asapbio.org/about/faq/pr...
Reposted by Jack Wilkinson
We have senior people in our department telling PhD students not to post preprints as journals will refuse to publish due to prior publication. Is there anywhere in health this is actually true? Genuine question, but I doubt it?
October 24, 2025 at 1:09 PM
We have senior people in our department telling PhD students not to post preprints as journals will refuse to publish due to prior publication. Is there anywhere in health this is actually true? Genuine question, but I doubt it?
Reposted by Jack Wilkinson
Free online workshop for assessing trustworthiness of RCTs
Introductory online INSPECT-SR workshop. November 6th, 12-2pm UK-time. Free, places limited. BOOK: www.trybooking.com/uk/events/la...
Introduction to INSPECT-SR Training Workshop November
An introductory 2-hour online workshop will introduce participants to the INSPECT-SR tool for assessing trustworthiness of randomised controlled...
www.trybooking.com
October 22, 2025 at 8:16 AM
Free online workshop for assessing trustworthiness of RCTs
I agree with Tim that the value of target trials is to help think about assumptions and limitations (what we would like to do vs what we can do). But I fear it is going to be used differently-to minimise limitations, implying a NRSI is as good as randomised tpmorris.substack.com/p/firing-at-...
Firing at Target
The Target statement recently appeared in JAMA, and I hereby confer it with two acronym-related awards: “Most dubious” and possibly “Longest gap between two successive letters in the acronym”.
tpmorris.substack.com
October 21, 2025 at 3:55 PM
I agree with Tim that the value of target trials is to help think about assumptions and limitations (what we would like to do vs what we can do). But I fear it is going to be used differently-to minimise limitations, implying a NRSI is as good as randomised tpmorris.substack.com/p/firing-at-...
Reposted by Jack Wilkinson
Introductory online INSPECT-SR workshop. November 6th, 12-2pm UK-time. Free, places limited. BOOK: www.trybooking.com/uk/events/la...
Introduction to INSPECT-SR Training Workshop November
An introductory 2-hour online workshop will introduce participants to the INSPECT-SR tool for assessing trustworthiness of randomised controlled...
www.trybooking.com
October 3, 2025 at 11:08 AM
Introductory online INSPECT-SR workshop. November 6th, 12-2pm UK-time. Free, places limited. BOOK: www.trybooking.com/uk/events/la...
Introductory online INSPECT-SR workshop. November 6th, 12-2pm UK-time. Free, places limited. BOOK: www.trybooking.com/uk/events/la...
Introduction to INSPECT-SR Training Workshop November
An introductory 2-hour online workshop will introduce participants to the INSPECT-SR tool for assessing trustworthiness of randomised controlled...
www.trybooking.com
October 3, 2025 at 11:08 AM
Introductory online INSPECT-SR workshop. November 6th, 12-2pm UK-time. Free, places limited. BOOK: www.trybooking.com/uk/events/la...
Trying to reproduce results from old papers can take you to interesting places
September 18, 2025 at 1:36 PM
Trying to reproduce results from old papers can take you to interesting places
Reposted by Jack Wilkinson
International #ResearchIntegrity conference 16-18 November 2025
Come to hear @elisabethbik.bsky.social Ivan Oransky @jamesheathers.bsky.social @retractionwatch.com Lisa Bero @liammannix.bsky.social @jdwilko.bsky.social @jacksonwryan.com +many others, stay for Sydney in late Spring @sydney.edu.au 🧪
Come to hear @elisabethbik.bsky.social Ivan Oransky @jamesheathers.bsky.social @retractionwatch.com Lisa Bero @liammannix.bsky.social @jdwilko.bsky.social @jacksonwryan.com +many others, stay for Sydney in late Spring @sydney.edu.au 🧪
International Research Integrity Conference researchintegrityconf.com has been moved to University of Sydney (Refectory and Cullen rooms) Nov 16-18th 2025. Registrations filling fast
International Research Integrity Conference | 16-18 November 2025, Sydney, Australia
researchintegrityconf.com
September 14, 2025 at 1:08 AM
International #ResearchIntegrity conference 16-18 November 2025
Come to hear @elisabethbik.bsky.social Ivan Oransky @jamesheathers.bsky.social @retractionwatch.com Lisa Bero @liammannix.bsky.social @jdwilko.bsky.social @jacksonwryan.com +many others, stay for Sydney in late Spring @sydney.edu.au 🧪
Come to hear @elisabethbik.bsky.social Ivan Oransky @jamesheathers.bsky.social @retractionwatch.com Lisa Bero @liammannix.bsky.social @jdwilko.bsky.social @jacksonwryan.com +many others, stay for Sydney in late Spring @sydney.edu.au 🧪
Reposted by Jack Wilkinson
Nearly 3 months since I contacted both the authors and editor of @jama.com about failure to share data.
Article states data and code is available, but the github repo is empty.
Not private or partial, empty. Has never contained anything.
No replies from anyone.
jamanetwork.com/journals/jam...
Article states data and code is available, but the github repo is empty.
Not private or partial, empty. Has never contained anything.
No replies from anyone.
jamanetwork.com/journals/jam...
Addictive Screen Use Trajectories and Suicidal Behaviors, Suicidal Ideation, and Mental Health in US Youths
This cohort study identifies trajectories of addictive use of social media, mobile phones, and video games among US youths and examines their associations with suicidal behaviors and ideation and ment...
jamanetwork.com
September 8, 2025 at 7:52 AM
Nearly 3 months since I contacted both the authors and editor of @jama.com about failure to share data.
Article states data and code is available, but the github repo is empty.
Not private or partial, empty. Has never contained anything.
No replies from anyone.
jamanetwork.com/journals/jam...
Article states data and code is available, but the github repo is empty.
Not private or partial, empty. Has never contained anything.
No replies from anyone.
jamanetwork.com/journals/jam...
For Monday crowd. INSPECT-SR, a tool to help you identify problematic (inc. fraudulent) RCTs, now available.
www.medrxiv.org/content/10.1...
INSPECT-SR: A tool for assessing trustworthiness of randomised controlled trials.
INSPECT-SR: A tool for assessing trustworthiness of randomised controlled trials.
INSPECT-SR: a tool for assessing trustworthiness of randomised controlled trials
The integrity of evidence synthesis is threatened by problematic randomised controlled trials (RCTs). These are RCTs where there are serious concerns about the trustworthiness of the data or findings....
www.medrxiv.org
September 8, 2025 at 7:22 AM
For Monday crowd. INSPECT-SR, a tool to help you identify problematic (inc. fraudulent) RCTs, now available.
Reposted by Jack Wilkinson
📚 INSPECT-SR: a tool for assessing trustworthiness of randomised controlled trials www.medrxiv.org/content/10.1...
INSPECT-SR: a tool for assessing trustworthiness of randomised controlled trials
The integrity of evidence synthesis is threatened by problematic randomised controlled trials (RCTs). These are RCTs where there are serious concerns about the trustworthiness of the data or findings....
www.medrxiv.org
September 6, 2025 at 9:26 AM
📚 INSPECT-SR: a tool for assessing trustworthiness of randomised controlled trials www.medrxiv.org/content/10.1...
Reposted by Jack Wilkinson
Science is not always as good as it appears on print in a research paper. Ready to be scared by finding nasty truths. Try out INSPECT-SR for checking the trustworthiness of trial results when you do systematic reviews.
September 5, 2025 at 7:11 PM
Science is not always as good as it appears on print in a research paper. Ready to be scared by finding nasty truths. Try out INSPECT-SR for checking the trustworthiness of trial results when you do systematic reviews.
www.medrxiv.org/content/10.1...
INSPECT-SR: A tool for assessing trustworthiness of randomised controlled trials.
INSPECT-SR: A tool for assessing trustworthiness of randomised controlled trials.
INSPECT-SR: a tool for assessing trustworthiness of randomised controlled trials
The integrity of evidence synthesis is threatened by problematic randomised controlled trials (RCTs). These are RCTs where there are serious concerns about the trustworthiness of the data or findings....
www.medrxiv.org
September 5, 2025 at 6:11 PM
www.medrxiv.org/content/10.1...
INSPECT-SR: A tool for assessing trustworthiness of randomised controlled trials.
INSPECT-SR: A tool for assessing trustworthiness of randomised controlled trials.
Reposted by Jack Wilkinson
One of the most common misunderstandings about the use and value of placebos in clinical RCTs, often made by both methodological experts and experienced trialists:
(from @stephensenn.bsky.social in academic.oup.com/jrsssa/advan...)
(from @stephensenn.bsky.social in academic.oup.com/jrsssa/advan...)
September 5, 2025 at 5:52 AM
One of the most common misunderstandings about the use and value of placebos in clinical RCTs, often made by both methodological experts and experienced trialists:
(from @stephensenn.bsky.social in academic.oup.com/jrsssa/advan...)
(from @stephensenn.bsky.social in academic.oup.com/jrsssa/advan...)
Hoping INSPECT-SR will appear on medRxiV at some point today…
September 4, 2025 at 7:24 AM
Hoping INSPECT-SR will appear on medRxiV at some point today…
Last chance to participate - this will close on Sunday pm UK time. These results will be used to formulate guidance on demonstrating promise of an intervention when applying for funding for an RCT, pilot, or feasibility trial.
How to demonstrate ‘promise of the intervention’ ahead of an RCT of the intervention? If you’d like to participate in the final round of the Promise Delphi, even if you didn’t do Round 1, then get in touch!
August 20, 2025 at 8:20 AM
Last chance to participate - this will close on Sunday pm UK time. These results will be used to formulate guidance on demonstrating promise of an intervention when applying for funding for an RCT, pilot, or feasibility trial.
Reposted by Jack Wilkinson
A letter from myself and @jdwilko.bsky.social that expands on this a bit more. Thanks to Fertility and Sterility for the opportunity.
doi.org/10.1016/j.fe...
doi.org/10.1016/j.fe...
August 12, 2025 at 9:54 AM
A letter from myself and @jdwilko.bsky.social that expands on this a bit more. Thanks to Fertility and Sterility for the opportunity.
doi.org/10.1016/j.fe...
doi.org/10.1016/j.fe...
How to demonstrate ‘promise of the intervention’ ahead of an RCT of the intervention? If you’d like to participate in the final round of the Promise Delphi, even if you didn’t do Round 1, then get in touch!
August 11, 2025 at 7:22 AM
How to demonstrate ‘promise of the intervention’ ahead of an RCT of the intervention? If you’d like to participate in the final round of the Promise Delphi, even if you didn’t do Round 1, then get in touch!
Any OSF-heads have suggestions here? I noticed a typo in a public OSF document I had uploaded. So I deleted and uploaded the corrected version. But the new version (a Word document, same as the previous doc) won't display - 'Unexpected server response'. Any ideas?
August 8, 2025 at 10:33 AM
Any OSF-heads have suggestions here? I noticed a typo in a public OSF document I had uploaded. So I deleted and uploaded the corrected version. But the new version (a Word document, same as the previous doc) won't display - 'Unexpected server response'. Any ideas?
Reposted by Jack Wilkinson
Did you have a chance to catch @davidhosch.bsky.social, @neiloconnell.bsky.social, @jdwilko.bsky.social, @nadiasoliman.bsky.social, @lesleyuttley.bsky.social discuss “trustworthiness” in clinical trial data? Watch the recording here bit.ly/4luQVMS
July 28, 2025 at 7:00 PM
Did you have a chance to catch @davidhosch.bsky.social, @neiloconnell.bsky.social, @jdwilko.bsky.social, @nadiasoliman.bsky.social, @lesleyuttley.bsky.social discuss “trustworthiness” in clinical trial data? Watch the recording here bit.ly/4luQVMS
Happening now!
Have you wanted to understand what is meant by “trustworthy” research? Attend this #webinar TODAY to hear from @davidhosch.bsky.social, @neiloconnell.bsky.social, @jdwilko.bsky.social, @nadiasoliman.bsky.social, @lesleyuttley.bsky.social bit.ly/4kSQjjy
July 21, 2025 at 2:06 PM
Happening now!