Jonathan D. Good
@jdgood1.bsky.social
Reposted by Jonathan D. Good
#ASH25 is almost here and the latest #ASHinaFlash has everything you need to know about clonal hematopoiesis before you arrive. Dr. Peter van Galen's session explores how clonal hematopoiesis influences leukemia risk, cardiovascular health, and more.
Register today: https://ow.ly/6pbU50XyfqN
Register today: https://ow.ly/6pbU50XyfqN
November 26, 2025 at 4:31 PM
#ASH25 is almost here and the latest #ASHinaFlash has everything you need to know about clonal hematopoiesis before you arrive. Dr. Peter van Galen's session explores how clonal hematopoiesis influences leukemia risk, cardiovascular health, and more.
Register today: https://ow.ly/6pbU50XyfqN
Register today: https://ow.ly/6pbU50XyfqN
Reposted by Jonathan D. Good
Ferroptosis and 🩸 stem cell biology have a lot to say to each other... Hoping this work inspires #ferroptosis researchers to explore HSCs and #hematopoiesis researchers to lean into ferroptosis 🤝
Excited to share our new study, led by @dellaVolpe_L, now out in @natcellbio.nature.com! Blocking #ferroptosis enhances human 🩸 stem cell expansion, with implications for transplantation and gene therapy. www.nature.com/articles/s41...
November 19, 2025 at 10:07 PM
Ferroptosis and 🩸 stem cell biology have a lot to say to each other... Hoping this work inspires #ferroptosis researchers to explore HSCs and #hematopoiesis researchers to lean into ferroptosis 🤝
Reposted by Jonathan D. Good
Excited to share our new study, led by @dellaVolpe_L, now out in @natcellbio.nature.com! Blocking #ferroptosis enhances human 🩸 stem cell expansion, with implications for transplantation and gene therapy. www.nature.com/articles/s41...
November 18, 2025 at 5:49 PM
Excited to share our new study, led by @dellaVolpe_L, now out in @natcellbio.nature.com! Blocking #ferroptosis enhances human 🩸 stem cell expansion, with implications for transplantation and gene therapy. www.nature.com/articles/s41...
Reposted by Jonathan D. Good
Thank you to everyone involved! Maria Capilla-Guerra, Andre Monteleone, Jonathan Young, Subha Shankar, Phillip Michaels, Harrison Tsai, @jdgood1.bsky.social, Antonia Kreso, @vangalenlab.bsky.social, Christoph Schliemann and Evan Chen. @danafarber.bsky.social @broadinstitute.org (11/11)
September 22, 2025 at 9:10 PM
Thank you to everyone involved! Maria Capilla-Guerra, Andre Monteleone, Jonathan Young, Subha Shankar, Phillip Michaels, Harrison Tsai, @jdgood1.bsky.social, Antonia Kreso, @vangalenlab.bsky.social, Christoph Schliemann and Evan Chen. @danafarber.bsky.social @broadinstitute.org (11/11)
Reposted by Jonathan D. Good
Excited to share our latest work on blood aging! To find out why the blood system changes as people age, we started at the source: hematopoietic stem cells (HSCs) #hemesky 🩸🧬 doi.org/10.1101/2025... 🧵 1/5
September 6, 2025 at 1:33 AM
Excited to share our latest work on blood aging! To find out why the blood system changes as people age, we started at the source: hematopoietic stem cells (HSCs) #hemesky 🩸🧬 doi.org/10.1101/2025... 🧵 1/5
Reposted by Jonathan D. Good
This new way of looking at cellular diversity in single-cell sequencing is transformative imo, which is why we've taken a similar approach to study aging blood stem cells. Congratulations @dkotliar.bsky.social and @soumya-boston.bsky.social! 🩸🧪🧬 #hemesky
Paper from me, Michelle Curtis, @soumya-boston.bsky.social and co out now in @natmethods.nature.com! We now call it starCAT instead of *CAT but the strategy is the same: Build a catalog of ~50 interpretable T cell gene expression programs + use them to interpret new data nature.com/articles/s41...
Reproducible single-cell annotation of programs underlying T cell subsets, activation states and functions - Nature Methods
TCAT is a pipeline that can simultaneously capture gene expression programs related to T cell subsets and activation states for accurate T cell characterization.
nature.com
September 6, 2025 at 11:52 PM
This new way of looking at cellular diversity in single-cell sequencing is transformative imo, which is why we've taken a similar approach to study aging blood stem cells. Congratulations @dkotliar.bsky.social and @soumya-boston.bsky.social! 🩸🧪🧬 #hemesky
Reposted by Jonathan D. Good
New insights into the Unfolded Protein Response in hematopoietic stem cells in @bloodjournal.bsky.social this week + commentary from @basitsalik.bsky.social and me🩸🐁 #hemesky doi.org/10.1182/bloo...
The PERKs of ER homeostasis for hematopoietic stem cells
In this issue of Blood, Zheng et al1 show that the unfolded protein response (UPR) sensor PERK (protein kinase R-like endoplasmic reticulum kinase) is disp
doi.org
August 15, 2025 at 3:12 PM
New insights into the Unfolded Protein Response in hematopoietic stem cells in @bloodjournal.bsky.social this week + commentary from @basitsalik.bsky.social and me🩸🐁 #hemesky doi.org/10.1182/bloo...
Reposted by Jonathan D. Good
Had a great time catching up with friends and learning new science at FASEB Hematologic Malignancies! #hemesky @faseborg.bsky.social #HEMSRC
August 2, 2025 at 1:48 PM
Had a great time catching up with friends and learning new science at FASEB Hematologic Malignancies! #hemesky @faseborg.bsky.social #HEMSRC
Reposted by Jonathan D. Good
We caught up with some Ludwig researchers at the #AACR25 Annual Meeting and asked them about their work. Ludwig @harvard.edu's Adrienne Parsons describes her research here: youtu.be/LBU_NAKIA7M
Adrienne Parsons at AACR 25
YouTube video by Ludwig Cancer Research
youtu.be
May 5, 2025 at 7:48 PM
We caught up with some Ludwig researchers at the #AACR25 Annual Meeting and asked them about their work. Ludwig @harvard.edu's Adrienne Parsons describes her research here: youtu.be/LBU_NAKIA7M
Reposted by Jonathan D. Good
Ludwig @harvard.edu’s Adrienne Parsons presented @ #AACR25 her work on age-associated differences in cell states and interactions in estrogen receptor-positive and triple-negative breast cancers—work that provides clues to age-adapted interventions for breast cancer therapy.
May 2, 2025 at 5:35 PM
Ludwig @harvard.edu’s Adrienne Parsons presented @ #AACR25 her work on age-associated differences in cell states and interactions in estrogen receptor-positive and triple-negative breast cancers—work that provides clues to age-adapted interventions for breast cancer therapy.