Jay Lusk, MD, MBA
@jayblusk.bsky.social
Preventive medicine/public health physician, clinical data scientist. Driven to prevent chronic disease with big data. MD/MBA at Duke, currently preventive medicine residency at UNC. jaylusk.md
Proud to share my latest paper in @bmj.com www.bmj.com/content/389/.... Takeaways: Dementia incidence ⬇️, prevalence ⬆️, and dementia is unequally distributed. In an opinion article, I argue we need to redouble our efforts to manage multimorbidity across the life course: www.bmj.com/content/389/...
Incidence and prevalence of dementia among US Medicare beneficiaries, 2015-21: population based study
Objective To determine the incidence and prevalence of dementia in a nationally representative cohort of US Medicare beneficiaries, stratified by important subgroups.
Design Population based study.
...
www.bmj.com
May 24, 2025 at 11:27 AM
Proud to share my latest paper in @bmj.com www.bmj.com/content/389/.... Takeaways: Dementia incidence ⬇️, prevalence ⬆️, and dementia is unequally distributed. In an opinion article, I argue we need to redouble our efforts to manage multimorbidity across the life course: www.bmj.com/content/389/...
Reposted by Jay Lusk, MD, MBA
Smoking cigarettes is associated with developing both subtypes of HF, independent from baseline lung function.
Jackson Heart Study
#CardioSky #MedSky #JAHA
@robmentz.bsky.social @dranulala.bsky.social @anastasiasmihaili.bsky.social
@ahajournals.bsky.social
www.ahajournals.org/doi/10.1161/...
Jackson Heart Study
#CardioSky #MedSky #JAHA
@robmentz.bsky.social @dranulala.bsky.social @anastasiasmihaili.bsky.social
@ahajournals.bsky.social
www.ahajournals.org/doi/10.1161/...
December 16, 2024 at 1:25 AM
Smoking cigarettes is associated with developing both subtypes of HF, independent from baseline lung function.
Jackson Heart Study
#CardioSky #MedSky #JAHA
@robmentz.bsky.social @dranulala.bsky.social @anastasiasmihaili.bsky.social
@ahajournals.bsky.social
www.ahajournals.org/doi/10.1161/...
Jackson Heart Study
#CardioSky #MedSky #JAHA
@robmentz.bsky.social @dranulala.bsky.social @anastasiasmihaili.bsky.social
@ahajournals.bsky.social
www.ahajournals.org/doi/10.1161/...
Really essential to have patient perspectives centered in research around DBS. Very nice paper highlighting the complexity and nuance of patient experiences in this space.
Are there changes in personal characteristics following deep brain stimulation (DBS) in Parkinson's disease? I love that many responses did not reflect 'prototypical traits or behaviors reflected in standard measures, but instead reflect patient-specific values.'
December 2, 2024 at 1:19 PM
Really essential to have patient perspectives centered in research around DBS. Very nice paper highlighting the complexity and nuance of patient experiences in this space.
Excellent pragmatic trial out in Lancet showing that a traditional Chinese medicine did not improve ICH outcomes. Shows how important trials are for TCM/herbal interventions. Contrast with positive trial of tongxinluo published in JAMA last year. #MedSky #StrokeSky www.thelancet.com/journals/lan...
December 2, 2024 at 1:14 PM
Excellent pragmatic trial out in Lancet showing that a traditional Chinese medicine did not improve ICH outcomes. Shows how important trials are for TCM/herbal interventions. Contrast with positive trial of tongxinluo published in JAMA last year. #MedSky #StrokeSky www.thelancet.com/journals/lan...
Really interesting pragmatic, factorial trial of feedback to PCPs on antibiotic prescribing. Adds to literature from other settings (e.g. alcohol use among college students) that this type of comparison-based intervention can be powerful to drive behavior change. www.bmj.com/content/385/...
Mailed feedback to primary care physicians on antibiotic prescribing for patients aged 65 years and older: pragmatic, factorial randomised controlled trial
Objectives To evaluate whether providing family physicians with feedback on their antibiotic prescribing compared with that of their peers reduces antibiotic prescriptions. To also identify effects on...
www.bmj.com
November 29, 2024 at 4:32 AM
Really interesting pragmatic, factorial trial of feedback to PCPs on antibiotic prescribing. Adds to literature from other settings (e.g. alcohol use among college students) that this type of comparison-based intervention can be powerful to drive behavior change. www.bmj.com/content/385/...
Reposted by Jay Lusk, MD, MBA
Maybe instead grants, early career investigators will need to support their work through affiliate links and corporate brand deals in our manuscripts.
“Acknowledgements: We thank Peloton for supporting our work. Use the code ‘Green’ for 10% off a yearly subscription of workouts!”🧪🛟 #MedSky
“Acknowledgements: We thank Peloton for supporting our work. Use the code ‘Green’ for 10% off a yearly subscription of workouts!”🧪🛟 #MedSky
#NIH #NINDS paylines are at 8% for fiscal 2025. Tough year is due to increased research costs and federal budget uncertainty for FY 2025. Director's message here. Worth reading. www.ninds.nih.gov/news-events/...
Featured Director's Message
www.ninds.nih.gov
November 27, 2024 at 3:16 AM
Maybe instead grants, early career investigators will need to support their work through affiliate links and corporate brand deals in our manuscripts.
“Acknowledgements: We thank Peloton for supporting our work. Use the code ‘Green’ for 10% off a yearly subscription of workouts!”🧪🛟 #MedSky
“Acknowledgements: We thank Peloton for supporting our work. Use the code ‘Green’ for 10% off a yearly subscription of workouts!”🧪🛟 #MedSky
Reposted by Jay Lusk, MD, MBA
Now out in #AHAJournals Most studies focus on the association between socioeconomic disadvantage and 30-day Heart Failure readmissions, our work focuses on the cumulative impact on patient outcomes after diagnosis. #CardioSky #MedSky #HF @ahajournals.bsky.social www.ahajournals.org/doi/abs/10.1...
November 25, 2024 at 1:53 PM
Now out in #AHAJournals Most studies focus on the association between socioeconomic disadvantage and 30-day Heart Failure readmissions, our work focuses on the cumulative impact on patient outcomes after diagnosis. #CardioSky #MedSky #HF @ahajournals.bsky.social www.ahajournals.org/doi/abs/10.1...
Reposted by Jay Lusk, MD, MBA
New paper on how to calculate a multistate death distribution! What's that, you ask? Usually, we plot a death distribution by age at death. But age at death is the sum of our time spent in different states. If we split time between being healthy or not, then the distribution is multistate (1/3)
November 25, 2024 at 10:32 PM
New paper on how to calculate a multistate death distribution! What's that, you ask? Usually, we plot a death distribution by age at death. But age at death is the sum of our time spent in different states. If we split time between being healthy or not, then the distribution is multistate (1/3)
State medical board records have some amazing stories. Take this one. PA applies for a license in NC, submits license documentation. States she had changed her name, provides documents. Sounds legit. Licensed approved. Turns out, SHE STOLE ANOTHER PA’s identity?! License summarily suspended.
November 24, 2024 at 2:31 AM
State medical board records have some amazing stories. Take this one. PA applies for a license in NC, submits license documentation. States she had changed her name, provides documents. Sounds legit. Licensed approved. Turns out, SHE STOLE ANOTHER PA’s identity?! License summarily suspended.
New Lancet paper on disparities in life expectancy since 2000. In the “ten americas”, precipitous decline in life expectancy among “America 10” (1.3 million American Indian/Alaska Native residents in the west) stands out. Urgent need for policy interventions #MedSky www.thelancet.com/journals/lan...
November 23, 2024 at 2:37 AM
New Lancet paper on disparities in life expectancy since 2000. In the “ten americas”, precipitous decline in life expectancy among “America 10” (1.3 million American Indian/Alaska Native residents in the west) stands out. Urgent need for policy interventions #MedSky www.thelancet.com/journals/lan...
Intensive BP control stands out. We shouldn’t be exposing healthy 80 year old patients to chronic poorly controlled BP. Care required to avoid orthostatic hypotension and falls, but the consequences of undertreated HTN are dire. So much therapeutic nihilism about this… #MedSky #CardioSky #GeriSkys
Medicine focuses a lot on the question “will this help my patient” but not on the question “when will it help my patient.” The latter becomes important as we age. We’ve developed a “time-to-benefit” tool on eprognosis.ucsf.edu to help answer this question. Here is a snapshot
#MedSky #FOAMed #meded
#MedSky #FOAMed #meded
November 19, 2024 at 1:02 AM
Intensive BP control stands out. We shouldn’t be exposing healthy 80 year old patients to chronic poorly controlled BP. Care required to avoid orthostatic hypotension and falls, but the consequences of undertreated HTN are dire. So much therapeutic nihilism about this… #MedSky #CardioSky #GeriSkys
Best thing about #AHA2024 is the chance to catch up with shared connections: “academic families.” Wonderful to see @michaeldgreen.com + Duke Undergrad Perisa Ashar. Common thread is mentor Emily O’Brien who has been instrumental to all our careers and connections with each other #CardioSky #MedSky
November 19, 2024 at 12:10 AM
Best thing about #AHA2024 is the chance to catch up with shared connections: “academic families.” Wonderful to see @michaeldgreen.com + Duke Undergrad Perisa Ashar. Common thread is mentor Emily O’Brien who has been instrumental to all our careers and connections with each other #CardioSky #MedSky
Moderated an amazing presentation from @vinaykini.bsky.social #AHA2024 now published in @jaccjournals.bsky.social. Outstanding work with thoughtful causal inference methods to show no improvement in care quality after vertical integration of cardiology practices. #CardioSky #MedSky
November 18, 2024 at 11:11 PM
Moderated an amazing presentation from @vinaykini.bsky.social #AHA2024 now published in @jaccjournals.bsky.social. Outstanding work with thoughtful causal inference methods to show no improvement in care quality after vertical integration of cardiology practices. #CardioSky #MedSky
Primary prevention of heart failure ought to be a central focus of #preventivemedicine and chronic disease prevention. Everything we do to prevent heart failure in primary care and prevention clinics will have positive knock-on effects on other CVD and prevent multimorbidity accumulation.
We need to move toward new primary prevention paradigms in heart failure. #AHA24 @ahascience.bsky.social
November 18, 2024 at 11:05 PM
Primary prevention of heart failure ought to be a central focus of #preventivemedicine and chronic disease prevention. Everything we do to prevent heart failure in primary care and prevention clinics will have positive knock-on effects on other CVD and prevent multimorbidity accumulation.
Great slate of #healthpolicy #qcor moderated posters here at #aha2024. Come join Paula Chatterjee and I at MDP12 in Zone 3 to hear some exciting work in cardiovascular health policy! #cardiosky #medsky
November 18, 2024 at 5:07 PM
Great slate of #healthpolicy #qcor moderated posters here at #aha2024. Come join Paula Chatterjee and I at MDP12 in Zone 3 to hear some exciting work in cardiovascular health policy! #cardiosky #medsky
Any #aha2024 #cardiosky #neurosky interested in whether INR levels predict ischemic stroke severity for patients taking DOACs? Come over to Zone 4 (4047) and take a look at our poster.
November 17, 2024 at 5:53 PM
Any #aha2024 #cardiosky #neurosky interested in whether INR levels predict ischemic stroke severity for patients taking DOACs? Come over to Zone 4 (4047) and take a look at our poster.
Great presentations at #aha2024. Come to MDP Session 13 to hear the exciting work! #cardiosky
November 16, 2024 at 7:14 PM
Great presentations at #aha2024. Come to MDP Session 13 to hear the exciting work! #cardiosky
Small, retrospective study evaluating CPAP for secondary prevention of CVD after AMI. As expected, long-term adherence to CPAP (>4 hours per night) is associated with 50% decreased risk of recurrent MACCE. I suspect impact on #htn control may drive effect. Need for larger and prospective studies.
November 16, 2024 at 4:08 PM
Small, retrospective study evaluating CPAP for secondary prevention of CVD after AMI. As expected, long-term adherence to CPAP (>4 hours per night) is associated with 50% decreased risk of recurrent MACCE. I suspect impact on #htn control may drive effect. Need for larger and prospective studies.
Incredible evidence to support more focus on control of #htn. Hyperglycemia is not the only contributor to CVD risk in T2DM. We can’t be content with SBPs in the 130s. Time to tackle therapeutic inertia in HTN treatment!
Amazing results from BPROAD trial showing lowering BP in T2DM to SBP<120 vs <140 mmHg reduces 4 points MACE HR0.79(.69-.9). Will be interesting to see how many are on SGLT2i or GLP1ra #AHA24
November 16, 2024 at 3:59 PM
Incredible evidence to support more focus on control of #htn. Hyperglycemia is not the only contributor to CVD risk in T2DM. We can’t be content with SBPs in the 130s. Time to tackle therapeutic inertia in HTN treatment!
Another incredible win for GLP-1RA/GIP Tirzepatide in SUMMIT! 38% reduction in CVD death/worsening HF and improved patient-reported outcomes. Time for policy change to get these therapies to patients with #obesity #hfpef #aha2024 #cardiosky
November 16, 2024 at 3:50 PM
Another incredible win for GLP-1RA/GIP Tirzepatide in SUMMIT! 38% reduction in CVD death/worsening HF and improved patient-reported outcomes. Time for policy change to get these therapies to patients with #obesity #hfpef #aha2024 #cardiosky
Hi everyone! I am a preventive medicine physician and clinician-scientist in clinical data science and #populationhealth. I’m excited to leverage the power of #bigdata to improve care for #chronicdisease. You can learn more about me at jaylusk.md. Hope to meet other #publichealth folks here!
Jay Lusk
jaylusk.md
November 16, 2024 at 1:45 PM
Hi everyone! I am a preventive medicine physician and clinician-scientist in clinical data science and #populationhealth. I’m excited to leverage the power of #bigdata to improve care for #chronicdisease. You can learn more about me at jaylusk.md. Hope to meet other #publichealth folks here!