Jaakko Lehtimäki
@jalehtimaki.bsky.social
Currently post-doc @CellMigrationLab, previously @NordenLab. PhD from @LabLappalainen. Fascinated by cells on the move, zebrafish and boulders.
2. Attraction through Gfrα1 receptor (HC) and Neurturin secreted from apical photoreceptors.
-Weaker cue ensuring HCs reach the photoreceptors. Take both Neurturin and Robo2 out and majority of HCs (cyan + yellow) are misplaced in the amacrine cell layer (yellow).
-Weaker cue ensuring HCs reach the photoreceptors. Take both Neurturin and Robo2 out and majority of HCs (cyan + yellow) are misplaced in the amacrine cell layer (yellow).
July 25, 2025 at 5:46 AM
2. Attraction through Gfrα1 receptor (HC) and Neurturin secreted from apical photoreceptors.
-Weaker cue ensuring HCs reach the photoreceptors. Take both Neurturin and Robo2 out and majority of HCs (cyan + yellow) are misplaced in the amacrine cell layer (yellow).
-Weaker cue ensuring HCs reach the photoreceptors. Take both Neurturin and Robo2 out and majority of HCs (cyan + yellow) are misplaced in the amacrine cell layer (yellow).
1. Repulsion through Robo2 receptor (HC) and Slit1b/2, expressed by the basal amacrine cells (yellow).
-Without Robo2 HCs (cyan + yellow), especially the ones further away from photoreceptor cell layer (grey arrowheads), fail to laminate correctly.
-Without Robo2 HCs (cyan + yellow), especially the ones further away from photoreceptor cell layer (grey arrowheads), fail to laminate correctly.
July 25, 2025 at 5:46 AM
1. Repulsion through Robo2 receptor (HC) and Slit1b/2, expressed by the basal amacrine cells (yellow).
-Without Robo2 HCs (cyan + yellow), especially the ones further away from photoreceptor cell layer (grey arrowheads), fail to laminate correctly.
-Without Robo2 HCs (cyan + yellow), especially the ones further away from photoreceptor cell layer (grey arrowheads), fail to laminate correctly.
Interested in cell migration yet bored of the canonical translocation modes? 😴 Don’t worry — we @nordenlab.bsky.social with @aiopticalbiolab.bsky.social have multipolar migration back in stock! No need to follow the other cells: extend long protrusions and roam more freely🪼 in the crowded brain.
July 25, 2025 at 5:46 AM
Interested in cell migration yet bored of the canonical translocation modes? 😴 Don’t worry — we @nordenlab.bsky.social with @aiopticalbiolab.bsky.social have multipolar migration back in stock! No need to follow the other cells: extend long protrusions and roam more freely🪼 in the crowded brain.
After ~3.5 inspiring years @nordenlab.bsky.social, I’ve migrated back to 'apical' Finland. The last months, I appeared a lot like these multipolar retinal cells. Excited to share more soon about their fascinating in vivo navigation!
January 7, 2025 at 11:11 AM
After ~3.5 inspiring years @nordenlab.bsky.social, I’ve migrated back to 'apical' Finland. The last months, I appeared a lot like these multipolar retinal cells. Excited to share more soon about their fascinating in vivo navigation!