Jack Goodall
@jackwgoodall.bsky.social
Sheffield Infectious Diseases Registrar //
NIHR researcher //
Interested in molecular diagnostics and transmission modelling //
Lover of art, literature, fermentation and the great outdoors //
NIHR researcher //
Interested in molecular diagnostics and transmission modelling //
Lover of art, literature, fermentation and the great outdoors //
Reposted by Jack Goodall
So this interview lasted 2 hours so this “you’re scaring me” part might seem like an overreaction or fearmongering to someone without that context.
There’s a lot of evidence to support my hypothesis that a potential H5N1 pandemic would be worse than COVID.
There’s a lot of evidence to support my hypothesis that a potential H5N1 pandemic would be worse than COVID.
April 21, 2025 at 1:28 PM
So this interview lasted 2 hours so this “you’re scaring me” part might seem like an overreaction or fearmongering to someone without that context.
There’s a lot of evidence to support my hypothesis that a potential H5N1 pandemic would be worse than COVID.
There’s a lot of evidence to support my hypothesis that a potential H5N1 pandemic would be worse than COVID.
Reposted by Jack Goodall
ID gurus - what are your thoughts on the optimal tx for S. pneumo meningitis that is pansensitive?
ESCMID guidelines: PCN or amp/amox
IDSA guidelines: PCN
NICE guidelines: Ceftriaxone
PCN: lower risk of CDiff, antimicrobial stewardship rizz
Ceftriaxone: fewer infusions, pt already on this
#IDsky
ESCMID guidelines: PCN or amp/amox
IDSA guidelines: PCN
NICE guidelines: Ceftriaxone
PCN: lower risk of CDiff, antimicrobial stewardship rizz
Ceftriaxone: fewer infusions, pt already on this
#IDsky
a woman says " i feel the conflict in you "
ALT: a woman says " i feel the conflict in you "
media.tenor.com
January 17, 2025 at 11:43 PM
ID gurus - what are your thoughts on the optimal tx for S. pneumo meningitis that is pansensitive?
ESCMID guidelines: PCN or amp/amox
IDSA guidelines: PCN
NICE guidelines: Ceftriaxone
PCN: lower risk of CDiff, antimicrobial stewardship rizz
Ceftriaxone: fewer infusions, pt already on this
#IDsky
ESCMID guidelines: PCN or amp/amox
IDSA guidelines: PCN
NICE guidelines: Ceftriaxone
PCN: lower risk of CDiff, antimicrobial stewardship rizz
Ceftriaxone: fewer infusions, pt already on this
#IDsky
Reposted by Jack Goodall
Our @shorten2trial.bsky.social aims to confirm that 7-day treatments are superior to 14-day courses for uncomplicated P. aeruginosa BSI.
Check out our full protocol 👉🏻 journals.plos.org/plosone/arti...
#AMSsky #IDSky
Check out our full protocol 👉🏻 journals.plos.org/plosone/arti...
#AMSsky #IDSky
November 21, 2024 at 8:07 AM
Our @shorten2trial.bsky.social aims to confirm that 7-day treatments are superior to 14-day courses for uncomplicated P. aeruginosa BSI.
Check out our full protocol 👉🏻 journals.plos.org/plosone/arti...
#AMSsky #IDSky
Check out our full protocol 👉🏻 journals.plos.org/plosone/arti...
#AMSsky #IDSky
Reposted by Jack Goodall
💉 How do we optimise the neutralising antibody responses of HSCT/CAR-T recipients following COVID vaccination? We found ChAdOx1-S recipients were EIGHT times more likely to have neutralising antibodies than those receiving mRNA vaccines in our new paper! Read more --> doi.org/10.1111/bjh....
Greater preservation of SARS‐CoV‐2 neutralising antibody responses following the ChAdOx1‐S (AZD1222) vaccine compared with mRNA vaccines in haematopoietic cell transplant recipients
Knowledge of factors impacting immune responses after COVID-19 vaccination is essential for guiding revaccination strategies in haematopoietic stem cell transplant (HSCT) and chimeric antigen recepto...
doi.org
November 19, 2024 at 12:46 PM
💉 How do we optimise the neutralising antibody responses of HSCT/CAR-T recipients following COVID vaccination? We found ChAdOx1-S recipients were EIGHT times more likely to have neutralising antibodies than those receiving mRNA vaccines in our new paper! Read more --> doi.org/10.1111/bjh....
Reposted by Jack Goodall
BIA now on blue sky 👏 - and please consider applying for our ECR and small project grants!
Grants: we provide travel and research grants for infection trainees and undergraduates. Scientific committee chair: @thushan-desilva.bsky.social
Our call for Early Career Research and Small Project Grants is open. Closing date 31st January 2025
www.britishinfection.org/research-gra...
Our call for Early Career Research and Small Project Grants is open. Closing date 31st January 2025
www.britishinfection.org/research-gra...
Grants | British Infection Association (BIA)
www.britishinfection.org
November 12, 2024 at 9:36 AM
BIA now on blue sky 👏 - and please consider applying for our ECR and small project grants!
This is a really useful insight that hopefully will guide how we prevent future spill overs
New preprint from Rwanda’s Marburg outbreak shows genetic evidence that the outbreak was due to a single spillover event, followed by human-to-human transmission that can be traced to the index case. 🧪🩺 IDSky www.medrxiv.org/content/10.1...
Genomic characterization uncovers transmission dynamics of Marburg Virus in Rwanda following a single zoonotic spillover event
The ongoing outbreak of Marburg virus disease (MVD) in Rwanda marks the third largest historically, though it has exhibited the lowest fatality rate. Genomic analysis has identified a lineage with lim...
www.medrxiv.org
November 8, 2024 at 5:44 PM
This is a really useful insight that hopefully will guide how we prevent future spill overs
R markdown is an amazing way to share pre-publication findings with colleagues and collaborators.
If you use R but haven't taken advantage of markdown then I have a tutorial just for you: jackwgoodall.github.io/floreytemplate
It's new so I would love your feedback.
#IDsky #AcademicSky #episky
If you use R but haven't taken advantage of markdown then I have a tutorial just for you: jackwgoodall.github.io/floreytemplate
It's new so I would love your feedback.
#IDsky #AcademicSky #episky
jackwgoodall.github.io
November 8, 2024 at 9:16 AM
R markdown is an amazing way to share pre-publication findings with colleagues and collaborators.
If you use R but haven't taken advantage of markdown then I have a tutorial just for you: jackwgoodall.github.io/floreytemplate
It's new so I would love your feedback.
#IDsky #AcademicSky #episky
If you use R but haven't taken advantage of markdown then I have a tutorial just for you: jackwgoodall.github.io/floreytemplate
It's new so I would love your feedback.
#IDsky #AcademicSky #episky
Reposted by Jack Goodall
New to this place 🦋, moving on from the other place
Here to provide you #EpiSky #IDsky updates from Europe's weekly, peer-reviewed scientific journal on infectious disease epidemiology, prevention & control
#PublicHealth
Submit your papers now for our annual theme 2025 😷💉
bit.ly/annualtheme25
Here to provide you #EpiSky #IDsky updates from Europe's weekly, peer-reviewed scientific journal on infectious disease epidemiology, prevention & control
#PublicHealth
Submit your papers now for our annual theme 2025 😷💉
bit.ly/annualtheme25
November 4, 2024 at 7:03 PM
New to this place 🦋, moving on from the other place
Here to provide you #EpiSky #IDsky updates from Europe's weekly, peer-reviewed scientific journal on infectious disease epidemiology, prevention & control
#PublicHealth
Submit your papers now for our annual theme 2025 😷💉
bit.ly/annualtheme25
Here to provide you #EpiSky #IDsky updates from Europe's weekly, peer-reviewed scientific journal on infectious disease epidemiology, prevention & control
#PublicHealth
Submit your papers now for our annual theme 2025 😷💉
bit.ly/annualtheme25
Reposted by Jack Goodall
🧵Next week, you will see people using something called Benford's Law to try to prove election fraud.
⛔️These people are wrong⛔️
I am a scientist who has published on Benford's Law. Let me tell you what it is and why what they are doing is mathematically incorrect. 1/
⛔️These people are wrong⛔️
I am a scientist who has published on Benford's Law. Let me tell you what it is and why what they are doing is mathematically incorrect. 1/
November 2, 2024 at 11:25 PM
🧵Next week, you will see people using something called Benford's Law to try to prove election fraud.
⛔️These people are wrong⛔️
I am a scientist who has published on Benford's Law. Let me tell you what it is and why what they are doing is mathematically incorrect. 1/
⛔️These people are wrong⛔️
I am a scientist who has published on Benford's Law. Let me tell you what it is and why what they are doing is mathematically incorrect. 1/
This is an amazing idea - using microbiome assessments to account for the inaccuracies that are invariably present in self reported diet recall www.nature.com/articles/s41...
Microbiome-based correction for random errors in nutrient profiles derived from self-reported dietary assessments - Nature Communications
Here, the authors introduce METRIC, a deep-learning method that corrects measurement errors in self-reported dietary nutrient profiles using assessed data and microbial composition, effectively enhanc...
www.nature.com
October 23, 2024 at 7:50 PM
This is an amazing idea - using microbiome assessments to account for the inaccuracies that are invariably present in self reported diet recall www.nature.com/articles/s41...
Reposted by Jack Goodall
Dear IDTwitter refugees
I made an #IDSky starter pack which makes it easy to find accounts of ID clinicians, medical microbiologists, ID researchers, ID epidemiologists, ID focused reporters, and of course journals ahead of the curve. Let me know if I missed you!
go.bsky.app/LnAQjdq
I made an #IDSky starter pack which makes it easy to find accounts of ID clinicians, medical microbiologists, ID researchers, ID epidemiologists, ID focused reporters, and of course journals ahead of the curve. Let me know if I missed you!
go.bsky.app/LnAQjdq
patrick star from spongebob squarepants is standing on a sandy beach next to a black line .
ALT: patrick star from spongebob squarepants is standing on a sandy beach next to a black line .
media.tenor.com
October 17, 2024 at 11:00 PM
Dear IDTwitter refugees
I made an #IDSky starter pack which makes it easy to find accounts of ID clinicians, medical microbiologists, ID researchers, ID epidemiologists, ID focused reporters, and of course journals ahead of the curve. Let me know if I missed you!
go.bsky.app/LnAQjdq
I made an #IDSky starter pack which makes it easy to find accounts of ID clinicians, medical microbiologists, ID researchers, ID epidemiologists, ID focused reporters, and of course journals ahead of the curve. Let me know if I missed you!
go.bsky.app/LnAQjdq
Reposted by Jack Goodall
Did it. Got approval to stop posting at X. Please #IDSky #MedSky people, feel free to follow @cmicomms.bsky.social, ESCMID's #OpenAccess journal on all things #infectiousdiseases, #clinicalmicrobiology, #AMR, and host of the #Communicable podcast, so I can show that we were right! :-)
October 11, 2024 at 5:28 PM
Did it. Got approval to stop posting at X. Please #IDSky #MedSky people, feel free to follow @cmicomms.bsky.social, ESCMID's #OpenAccess journal on all things #infectiousdiseases, #clinicalmicrobiology, #AMR, and host of the #Communicable podcast, so I can show that we were right! :-)
Reposted by Jack Goodall
"Exposure to healthcare has a large role in the transmission of infectious diseases and acquisition and transmission of antimicrobial resistance"
#IDSky #MicroSky #MedSky
www.bmj.com/content/387/...
#IDSky #MicroSky #MedSky
www.bmj.com/content/387/...
Protecting healthcare and patient pathways from infection and antimicrobial resistance
Innovative whole system approaches to integrate research and novel technologies within patient pathways are needed to target antibiotic use, minimise healthcare associated infections, and adapt to nov...
www.bmj.com
October 8, 2024 at 4:34 PM
"Exposure to healthcare has a large role in the transmission of infectious diseases and acquisition and transmission of antimicrobial resistance"
#IDSky #MicroSky #MedSky
www.bmj.com/content/387/...
#IDSky #MicroSky #MedSky
www.bmj.com/content/387/...
Reposted by Jack Goodall
Towards shorter, safer, flexible, and more effective treatment regimens for drug-resistant tuberculosis
#TB #IDSky 🩺🧪 #AMR
www.thelancet.com/journals/lan...
#TB #IDSky 🩺🧪 #AMR
www.thelancet.com/journals/lan...
Towards shorter, safer, flexible, and more effective treatment regimens for drug-resistant tuberculosis
There has been an important shift during the past 10 years in the approach to treating
drug-resistant tuberculosis.1 Around a decade ago, the treatment of multidrug-resistant
or rifampicin-resistant t...
www.thelancet.com
October 6, 2024 at 7:42 PM
Towards shorter, safer, flexible, and more effective treatment regimens for drug-resistant tuberculosis
#TB #IDSky 🩺🧪 #AMR
www.thelancet.com/journals/lan...
#TB #IDSky 🩺🧪 #AMR
www.thelancet.com/journals/lan...
academic.oup.com/ofid/article...
We have recently changed CSF viral panel and now get HHV6 results for all patients. Positive results in immunocompetent patients have caused a fair amount of debate (not least because of chromosomal integration). I found this review very helpful.
#IDSky
We have recently changed CSF viral panel and now get HHV6 results for all patients. Positive results in immunocompetent patients have caused a fair amount of debate (not least because of chromosomal integration). I found this review very helpful.
#IDSky
Diagnostic Dilemmas: A Review of Reported Cases of Human Herpesvirus 6 Encephalitis in Immunocompetent Adults
Human Herpesvirus-6 Encephalitis is exceedingly rare amongst the immunocompetent population. This review article identifies the available records of HHV-6
academic.oup.com
October 6, 2024 at 6:41 PM
academic.oup.com/ofid/article...
We have recently changed CSF viral panel and now get HHV6 results for all patients. Positive results in immunocompetent patients have caused a fair amount of debate (not least because of chromosomal integration). I found this review very helpful.
#IDSky
We have recently changed CSF viral panel and now get HHV6 results for all patients. Positive results in immunocompetent patients have caused a fair amount of debate (not least because of chromosomal integration). I found this review very helpful.
#IDSky
Reposted by Jack Goodall
The march of the mRNA vaccines goes on. Clostridiodes difficile (C diff) next...
#IDSky #MicroSky #MedSky 🧪
www.science.org/doi/10.1126/...
#IDSky #MicroSky #MedSky 🧪
www.science.org/doi/10.1126/...
A multivalent mRNA-LNP vaccine protects against Clostridioides difficile infection
Clostridioides difficile infection (CDI) is an urgent public health threat with limited preventative options. In this work, we developed a messenger RNA (mRNA)–lipid nanoparticle (LNP) vaccine targeti...
www.science.org
October 4, 2024 at 9:19 PM
The march of the mRNA vaccines goes on. Clostridiodes difficile (C diff) next...
#IDSky #MicroSky #MedSky 🧪
www.science.org/doi/10.1126/...
#IDSky #MicroSky #MedSky 🧪
www.science.org/doi/10.1126/...
www.independent.co.uk/news/health/...
We really need to get out of the mindset that outbreaks like this are only problematic when Western countries are at risk. This is devastating lives and healthcare systems in Rwanda.
We really need to get out of the mindset that outbreaks like this are only problematic when Western countries are at risk. This is devastating lives and healthcare systems in Rwanda.
Marburg virus outbreak: What you need to know as Europe fears cases
Virus, which has similarities to Ebola, has killed at least nine people during an outbreak in Rwanda
www.independent.co.uk
October 6, 2024 at 9:42 AM
www.independent.co.uk/news/health/...
We really need to get out of the mindset that outbreaks like this are only problematic when Western countries are at risk. This is devastating lives and healthcare systems in Rwanda.
We really need to get out of the mindset that outbreaks like this are only problematic when Western countries are at risk. This is devastating lives and healthcare systems in Rwanda.
Reposted by Jack Goodall
Delighted to share my first paper on Bluesky!
Managing UTIs is difficult and needs a multi-disciplinary approach. We discuss approaches on how to achive this...
Great collaborative effort led by @angelahuttner.bsky.social in @cmicomms.bsky.social #IDSky 🩺 #MedSky
www.cmi-comms.com/article/S295...
Managing UTIs is difficult and needs a multi-disciplinary approach. We discuss approaches on how to achive this...
Great collaborative effort led by @angelahuttner.bsky.social in @cmicomms.bsky.social #IDSky 🩺 #MedSky
www.cmi-comms.com/article/S295...
Establishing a dedicated UTI clinic: Challenges and a guide to success
Urinary tract infections (UTIs) have a significant impact on quality of life for patients
and present complex management issues that challenge healthcare systems. Recognizing
these challenges, dedicat...
www.cmi-comms.com
October 2, 2024 at 1:25 PM
Delighted to share my first paper on Bluesky!
Managing UTIs is difficult and needs a multi-disciplinary approach. We discuss approaches on how to achive this...
Great collaborative effort led by @angelahuttner.bsky.social in @cmicomms.bsky.social #IDSky 🩺 #MedSky
www.cmi-comms.com/article/S295...
Managing UTIs is difficult and needs a multi-disciplinary approach. We discuss approaches on how to achive this...
Great collaborative effort led by @angelahuttner.bsky.social in @cmicomms.bsky.social #IDSky 🩺 #MedSky
www.cmi-comms.com/article/S295...
This could be a real game changer for neutralisation assays. Think of those lab hours saved!!
Our paper describing a new sequencing-based neutralization assay for influenza virus is now published in Journal of Virology:
journals.asm.org/doi/10.1128/...
This new approach makes it possible to measure 100s (or even ~1000) neutralization titers in a single 96-well plate.
journals.asm.org/doi/10.1128/...
This new approach makes it possible to measure 100s (or even ~1000) neutralization titers in a single 96-well plate.
September 25, 2024 at 10:26 AM
This could be a real game changer for neutralisation assays. Think of those lab hours saved!!
Reposted by Jack Goodall
Our paper describing a new sequencing-based neutralization assay for influenza virus is now published in Journal of Virology:
journals.asm.org/doi/10.1128/...
This new approach makes it possible to measure 100s (or even ~1000) neutralization titers in a single 96-well plate.
journals.asm.org/doi/10.1128/...
This new approach makes it possible to measure 100s (or even ~1000) neutralization titers in a single 96-well plate.
September 24, 2024 at 6:36 PM
Our paper describing a new sequencing-based neutralization assay for influenza virus is now published in Journal of Virology:
journals.asm.org/doi/10.1128/...
This new approach makes it possible to measure 100s (or even ~1000) neutralization titers in a single 96-well plate.
journals.asm.org/doi/10.1128/...
This new approach makes it possible to measure 100s (or even ~1000) neutralization titers in a single 96-well plate.
Reposted by Jack Goodall
Out now: genomics analysis of Pseudomonas in bronchiectasis — expanding geography & increasing 10-fold publicly-available genomes. High diversity between patients, key genes undergoing parallel evolution or diversification, differences & similarities to CF. www.journalofinfection.com/article/S016...
Global genomic diversity of Pseudomonas aeruginosa in bronchiectasis
Pseudomonas aeruginosa is the most common pathogen in the bronchiectasis lung, associated
with worsened outcomes. P. aeruginosa genomic studies in this context have been limited
to single-country, Eur...
www.journalofinfection.com
September 25, 2024 at 7:15 AM
Out now: genomics analysis of Pseudomonas in bronchiectasis — expanding geography & increasing 10-fold publicly-available genomes. High diversity between patients, key genes undergoing parallel evolution or diversification, differences & similarities to CF. www.journalofinfection.com/article/S016...