Jonathan KM Lim
@j0nlim.bsky.social
Cancer biologist at @HHU / University Hospital Düsseldorf 🇩🇪
PhD @ UBC 🇨🇦
Interested in oncogenic RAS signaling, cancer metabolism, lncRNAs
GoogleScholar: https://g.co/kgs/jCXqEPN
Website: https://shorturl.at/IDSGc
PhD @ UBC 🇨🇦
Interested in oncogenic RAS signaling, cancer metabolism, lncRNAs
GoogleScholar: https://g.co/kgs/jCXqEPN
Website: https://shorturl.at/IDSGc
Reposted by Jonathan KM Lim
Since CXADR is a viral receptor, this study further paves the way for our novel virotherapy of #Ewing #sarcoma based on our 2022 study by @hoelting.bsky.social pioneering a suicde gene therapy induced by a Ewing sarcoma-specifc synthetic GGAA-enhancer
tinyurl.com/2sckk89m
tinyurl.com/2sckk89m
Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood sarcoma - Molecular Cancer
Chimeric fusion transcription factors are oncogenic hallmarks of several devastating cancer entities including pediatric sarcomas, such as Ewing sarcoma (EwS) and alveolar rhabdomyosarcoma (ARMS). Des...
tinyurl.com
August 11, 2025 at 6:41 AM
Since CXADR is a viral receptor, this study further paves the way for our novel virotherapy of #Ewing #sarcoma based on our 2022 study by @hoelting.bsky.social pioneering a suicde gene therapy induced by a Ewing sarcoma-specifc synthetic GGAA-enhancer
tinyurl.com/2sckk89m
tinyurl.com/2sckk89m
KRas mutant is Schrödinger’s enzyme
April 2, 2025 at 3:00 PM
KRas mutant is Schrödinger’s enzyme
Reposted by Jonathan KM Lim
Research Briefing: Starving tumors with fat www.nature.com/articles/s41...
Starving tumors with fat - Nature Biotechnology
Adipocytes can be isolated, genetically manipulated, and then reimplanted. In this study, these properties were leveraged to engineer adipocytes that can outcompete tumors for essential metabolic reso...
www.nature.com
February 6, 2025 at 4:27 PM
Research Briefing: Starving tumors with fat www.nature.com/articles/s41...