Ivan Gushchin
@ivangushchin.bsky.social
Structural biology and protein engineering
"Study of the effect of acoustic treatment on freezing point and boiling point of tap water" - way to go for a scientific journal www.nature.com/articles/s41...
October 29, 2025 at 7:39 PM
"Study of the effect of acoustic treatment on freezing point and boiling point of tap water" - way to go for a scientific journal www.nature.com/articles/s41...
Ubiquitin fold proteins are going to be even more ubiquitous
October 27, 2025 at 7:25 PM
Ubiquitin fold proteins are going to be even more ubiquitous
In my view, discovery of interactions and complexes is interesting/important, already advanced by AlphaFold and the like, and is not yet fully solved. Papers like these come to mind: doi.org/10.1016/j.ce... , doi.org/10.1126/scie... - but only some model organisms are covered so far
Redirecting
doi.org
October 17, 2025 at 4:21 AM
In my view, discovery of interactions and complexes is interesting/important, already advanced by AlphaFold and the like, and is not yet fully solved. Papers like these come to mind: doi.org/10.1016/j.ce... , doi.org/10.1126/scie... - but only some model organisms are covered so far
Previously, we engineered 3 artificial CagLOV-derived proteins doi.org/10.1002/pro.... - so I'm glad to see that the approach works for other LOVs as well
October 6, 2025 at 6:23 AM
Previously, we engineered 3 artificial CagLOV-derived proteins doi.org/10.1002/pro.... - so I'm glad to see that the approach works for other LOVs as well
They even succeed in engineering an ultrastable photoactive protein based on Atphot2 LOV2
October 6, 2025 at 6:23 AM
They even succeed in engineering an ultrastable photoactive protein based on Atphot2 LOV2
And now prohibitins!
www.pnas.org/doi/pdf/10.1...
www.pnas.org/doi/pdf/10.1...
September 27, 2025 at 8:05 PM
And now prohibitins!
www.pnas.org/doi/pdf/10.1...
www.pnas.org/doi/pdf/10.1...
More beautiful stomatin structures!
Happy to share a new preprint from the Clarke & Vallese (@fravallese.bsky.social) labs reporting #cryoem structures of two RBC stomatin complexes – with AQP1 & UT-B - continuing the SPFH theme from our recent vault preprint! This was a fun one and has been cooking for a while - read on for more! ⬇️
August 30, 2025 at 2:48 PM
More beautiful stomatin structures!
Congratulations! Great and inspiring work!
August 27, 2025 at 7:26 PM
Congratulations! Great and inspiring work!
This sequence, or sequence of some homologue, which is already released, would be great 🙏 ivan.gushchin@phystech.edu
July 26, 2025 at 2:13 PM
This sequence, or sequence of some homologue, which is already released, would be great 🙏 ivan.gushchin@phystech.edu