Andrea Manrique Rincón
@itreg.bsky.social
Scientist working with cancer immunotherapy, interested on metastasis, T cells and Tregs!
Reposted by Andrea Manrique Rincón
Out now in iScience!
@itreg.bsky.social in Annie Speak's lab created an in vitro model of T cell exhaustion to help identify and target new genes relevant to improving the immune response against cancer cells
www.cell.com/iscience/ful...
@itreg.bsky.social in Annie Speak's lab created an in vitro model of T cell exhaustion to help identify and target new genes relevant to improving the immune response against cancer cells
www.cell.com/iscience/ful...
July 1, 2025 at 9:53 AM
Out now in iScience!
@itreg.bsky.social in Annie Speak's lab created an in vitro model of T cell exhaustion to help identify and target new genes relevant to improving the immune response against cancer cells
www.cell.com/iscience/ful...
@itreg.bsky.social in Annie Speak's lab created an in vitro model of T cell exhaustion to help identify and target new genes relevant to improving the immune response against cancer cells
www.cell.com/iscience/ful...
Reposted by Andrea Manrique Rincón
This petition deserves a lot more publicity. Please share it.
Given its aim of growing the UK economy, we think the Government needs to quantify the effects of Brexit as soon as possible by setting up an inquiry.
petition.parliament.uk/petitions/70...
Given its aim of growing the UK economy, we think the Government needs to quantify the effects of Brexit as soon as possible by setting up an inquiry.
petition.parliament.uk/petitions/70...
Petition: Commission a public inquiry into the impact of the UK exiting the European Union
Given that it has stated its aim of growing the UK economy, we think the Government needs to quantify the effects of exiting the European Union as soon as possible by setting up an inquiry.
petition.parliament.uk
April 27, 2025 at 5:23 PM
This petition deserves a lot more publicity. Please share it.
Given its aim of growing the UK economy, we think the Government needs to quantify the effects of Brexit as soon as possible by setting up an inquiry.
petition.parliament.uk/petitions/70...
Given its aim of growing the UK economy, we think the Government needs to quantify the effects of Brexit as soon as possible by setting up an inquiry.
petition.parliament.uk/petitions/70...
Reposted by Andrea Manrique Rincón
Introducing The T Cell Show! 📺👩🔬
Follow along as a T cell interviews the immune system while a B cell undertakes a journey through the body, highlighting the specific immune functions of various organs.
Follow along as a T cell interviews the immune system while a B cell undertakes a journey through the body, highlighting the specific immune functions of various organs.
April 24, 2025 at 10:16 AM
Introducing The T Cell Show! 📺👩🔬
Follow along as a T cell interviews the immune system while a B cell undertakes a journey through the body, highlighting the specific immune functions of various organs.
Follow along as a T cell interviews the immune system while a B cell undertakes a journey through the body, highlighting the specific immune functions of various organs.
Reposted by Andrea Manrique Rincón
Local elections have low turnouts. We can swing the results against Farage by getting good people off their sofas and into the polling stations.
If you're angry with Labour, then there are the LibDems and Greens.
Abstaining helps the fascists.
Fight Fascism #Vote4Democracy
If you're angry with Labour, then there are the LibDems and Greens.
Abstaining helps the fascists.
Fight Fascism #Vote4Democracy
April 22, 2025 at 1:12 PM
Local elections have low turnouts. We can swing the results against Farage by getting good people off their sofas and into the polling stations.
If you're angry with Labour, then there are the LibDems and Greens.
Abstaining helps the fascists.
Fight Fascism #Vote4Democracy
If you're angry with Labour, then there are the LibDems and Greens.
Abstaining helps the fascists.
Fight Fascism #Vote4Democracy
Reposted by Andrea Manrique Rincón
We've made remarkable progress in the science of aging (geroscience) with readiness to apply this for "precision geromedicine."
A brilliant new review @cellpress.bsky.social
www.cell.com/cell/fulltex...
A brilliant new review @cellpress.bsky.social
www.cell.com/cell/fulltex...
April 19, 2025 at 4:07 PM
We've made remarkable progress in the science of aging (geroscience) with readiness to apply this for "precision geromedicine."
A brilliant new review @cellpress.bsky.social
www.cell.com/cell/fulltex...
A brilliant new review @cellpress.bsky.social
www.cell.com/cell/fulltex...
Reposted by Andrea Manrique Rincón
Synthetic Spore Husk-Encased Lipid bilayer (SSHELs) mimic bacterial spores and deliver peptides to dendritic cells, showing efficient tumor regression and improved survival in mice. SSHELs require complex synthesis but avoid cell culture use, unlike VLPs. #MedSky #MedEd #medschoolsky #immunosky
Welp, science moves on, I guess...
Our preprint reports that therapeutic immunization with synthetic spore-like particles, "SSHELs", encapsulation peptide antigen elicited antigen-specific T cell expansion, reduced tumor growth, and increased survival.
www.biorxiv.org/content/10.1...
Our preprint reports that therapeutic immunization with synthetic spore-like particles, "SSHELs", encapsulation peptide antigen elicited antigen-specific T cell expansion, reduced tumor growth, and increased survival.
www.biorxiv.org/content/10.1...
Immunization with peptide encapsulated within synthetic spores activates T cell responses and reduces tumor growth
Peptide-based therapeutic immunizations represent safe approaches to elicit antigen-specific T cell responses, but their broad utility remains limited due to poor immunogenicity and short in vivo stab...
www.biorxiv.org
March 4, 2025 at 10:28 PM
Synthetic Spore Husk-Encased Lipid bilayer (SSHELs) mimic bacterial spores and deliver peptides to dendritic cells, showing efficient tumor regression and improved survival in mice. SSHELs require complex synthesis but avoid cell culture use, unlike VLPs. #MedSky #MedEd #medschoolsky #immunosky
Reposted by Andrea Manrique Rincón
For the first time ever, we’re sitting down with the immune system itself! 🧪🎬
The T Cell Show is an animated talk show that explores how our bodies fight off infections and diseases.
Watch the first episode now: https://buff.ly/4hKClz8
@itreg.bsky.social
#ImmunoSky
The T Cell Show is an animated talk show that explores how our bodies fight off infections and diseases.
Watch the first episode now: https://buff.ly/4hKClz8
@itreg.bsky.social
#ImmunoSky
The T cell show
Chapter oneWhat is it, and how does the immune system work? For the first time ever, we will interview the famous immune system. It will tell us about its jo...
buff.ly
February 20, 2025 at 10:57 AM
For the first time ever, we’re sitting down with the immune system itself! 🧪🎬
The T Cell Show is an animated talk show that explores how our bodies fight off infections and diseases.
Watch the first episode now: https://buff.ly/4hKClz8
@itreg.bsky.social
#ImmunoSky
The T Cell Show is an animated talk show that explores how our bodies fight off infections and diseases.
Watch the first episode now: https://buff.ly/4hKClz8
@itreg.bsky.social
#ImmunoSky
Reposted by Andrea Manrique Rincón
Concurrent intratumoural Treg cell depletion and CD8+ T cell expansion via a cleavable anti-4-1BB–interleukin-15 fusion protein
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Concurrent intratumoural Treg cell depletion and CD8+ T cell expansion via a cleavable anti-4-1BB–interleukin-15 fusion protein - Nature Biomedical Engineering
An anti-4-1BB antibody fused to interleukin-15 via a peptide sensitive to tumour proteases augments tumour inhibition without increasing systemic toxicity by concurrently depleting regulatory T cells ...
www.nature.com
December 2, 2024 at 6:59 PM
Concurrent intratumoural Treg cell depletion and CD8+ T cell expansion via a cleavable anti-4-1BB–interleukin-15 fusion protein
www.nature.com/articles/s41...
www.nature.com/articles/s41...
