irenezorzan.bsky.social
@irenezorzan.bsky.social
Reposted
🔬 Love science and keeping a lab running smoothly? Join the @leeboratory.bsky.social as a lab manager/research technician and help uncover how cells choose and maintain their identity 🧫 More information ➡️ tinyurl.com/y7a8he88
December 19, 2025 at 10:15 AM
Reposted
A human embryo implantation model from the @Rugg-Gunn Lab

*key for understanding the early extraembryonic-maternal interactions

Congrats to everyone involved! It’s been great to see this project develop. Huge credit to the @babrahaminst.bsky.social authors 🥂🍾

www.cell.com/cell/fulltex...
December 24, 2025 at 8:45 AM
Very excited to finally share this work! 🥳🎊🎉Huge thanks to my former colleagues, the collaborators and @grazianomartello.bsky.social. See the post below for more info:
December 23, 2025 at 5:11 PM
Reposted
🚨 New paper out!
A human epiblast model reveals how dynamic TGF‑β signalling controls epithelial identity in early mammalian development
Here is the full paper: rdcu.be/eSWEs
🧵 A twittorial:
THREAD
A human epiblast model reveals dynamic TGFβ-mediated control of epithelial identity during mammalian epiblast development
Nature Cell Biology - The authors optimize an in vitro human epiblast model, which they utilize to show that early TGFβ family inhibition prevents epithelial identity, whereas it is...
rdcu.be
December 11, 2025 at 1:32 PM
Reposted
We are recruiting a Junior Technician to support research at the Loke CTR.

This role would be a great opportunity for someone looking to gain hands-on lab experience before pursuing further study or a career in research.

Application deadline: 21 April

www.jobs.cam.ac.uk/job/50706/
March 20, 2025 at 11:05 AM
Reposted
Join us at the Institute on 1st & 2nd May for our Signalling Symposium to celebrate Phill Hawkins and Len Stephens.

🧪 Sessions on #proteostasis, #PI3K, #autophagy, #redox biology and #nuclear signalling.

www.eventbrite.co.uk/e/cellular-s...
Cellular signals for health & disease
A symposium marking the contributions of Len Stephens and Phillip Hawkins
www.eventbrite.co.uk
March 20, 2025 at 4:49 PM
Reposted
Who knew development could be this exciting! Then again, they were preaching to the choir 🤍 amazing talks from Nicolas Rivron, @irenezorzan.bsky.social, @komal-yasmin.bsky.social , good discussions, and lasting friendships and collaborations 😎 @babrahaminst.bsky.social @crg.eu
February 27, 2025 at 3:20 PM
Reposted
Now that we are in Barcelona we have jumped right into some fantastic science! From chromatin structure and pathogenic fungi to having a deep and existential think about our omics approaches 🤔 😎 #CRGBIpostdocs @crg.eu @babrahaminst.bsky.social
Wonderful first session at #CRGBIpostdocs Huge thank you to our keynote speaker @mariekeoudelaar.bsky.social (@mpi-nat.bsky.social) and short talk presenters Alex Whale (@babrahaminst.bsky.social) , @ianakim.bsky.social (crg.eu) and Raj Sewduth (@viblifesciences.bsky.social, @eu-life.bsky.social) 👩‍🔬👨‍🔬
February 26, 2025 at 5:45 PM
Reposted
With the #CRGBIpostdocs symposium underway, we're shouting out our Babraham speakers! First up is Alex Whale from the Houseley lab, speaking at 4.30pm today. He'll talk about extrachromosomal circular DNA and the emergence of drug resistance 🧫
February 26, 2025 at 2:41 PM
Reposted
🚀 Off we go! ✈️ An early flight to kick off the International Postdoc Symposium! @crg.eu @babrahaminst.bsky.social Excited for an inspiring few days ahead! #CRGBIpostdocs
February 26, 2025 at 11:51 AM
Reposted
Only a few more days to wait for our postdocs before they head to @crg.eu for a joint symposium! Organised by postdocs for postdocs, this event aims to share research, expand networks, and develop key skills for research and beyond. #CRGBIpostdocs

Full program:
Centre for Genomic Regulation Website
buff.ly
February 21, 2025 at 11:12 AM
Reposted
Our new #preprint has:
✅ A KRAB Zinc Finger (the SCAN domain-containing kind)
#transposon sequences (the SINE kind)
#epigenetic regulation (the #enhancer kind)
✅ lineage specification (the neural kind)
❌ and NO heterochromatin!

All by PhD student Daniel Moore 🚀

www.biorxiv.org/content/10.1...
The KRAB-Zinc Finger protein ZKSCAN3 represses enhancers via embedded retrotransposons
Gene cis -regulatory sequences are increasingly recognised as containing “domesticated” transposable elements that impact their function. The KRAB Zinc Finger Protein (KZFP) family of transcription fa...
www.biorxiv.org
February 6, 2025 at 1:27 PM