Butt Lab - Oxford
@interneuron.bsky.social
How the mammalian brain comes online with a focus on local GABAergic interneurons | electrophysiology & imaging | in vitro & in vivo approaches 🧠🧪
Reposted by Butt Lab - Oxford
Out today at Neuron, our experiments show that frontal cortical representation of economic variables is jointly determined by spatial organization and downstream
connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...
connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...
October 16, 2025 at 3:00 PM
Out today at Neuron, our experiments show that frontal cortical representation of economic variables is jointly determined by spatial organization and downstream
connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...
connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...
Reposted by Butt Lab - Oxford
Excited to highlight a new paper from my graduate student Sergio Bernal Garcia who, together withLuke Hammond, developed RESPAN, a new deep-learning pipeline automating the segmentation of neuronal morphology and dendritic spines from fluorescent microscopy images:
www.cell.com/cell-reports...
www.cell.com/cell-reports...
A deep learning pipeline for accurate and automated restoration, segmentation, and quantification of dendritic spines
Garcia et al. present RESPAN, a pipeline that enables automated dendritic spine analysis
through seamless integration of deep learning image restoration and segmentation capabilities
with comprehensiv...
www.cell.com
September 21, 2025 at 1:01 PM
Excited to highlight a new paper from my graduate student Sergio Bernal Garcia who, together withLuke Hammond, developed RESPAN, a new deep-learning pipeline automating the segmentation of neuronal morphology and dendritic spines from fluorescent microscopy images:
www.cell.com/cell-reports...
www.cell.com/cell-reports...
A rather 'unique' paper from our lab is online in @cp-cellreports.bsky.social now. Unique in the sense that I don't think anyone else will be rushing to optotag cortical interneurons in the early postnatal brain... because it is nigh on impossible!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
GABAergic circuits reflect different requirements for sensory integration in postnatal mouse neocortex
Information transfer in mammalian cerebral cortex is dependent on GABAergic interneuron circuits that are widely assumed to be uniform across the neoc…
www.sciencedirect.com
September 18, 2025 at 4:16 PM
A rather 'unique' paper from our lab is online in @cp-cellreports.bsky.social now. Unique in the sense that I don't think anyone else will be rushing to optotag cortical interneurons in the early postnatal brain... because it is nigh on impossible!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Butt Lab - Oxford
Two faculty positions in my department this year. Please spread the word! And don't hesitate to reach out if you want to learn more.
Heads up! We are doing two searches this year—for an assistant prof in Clinical Science, and an associate/full prof in any domain of psychology. Want to learn more? Contact the dept chair, Mark Blumberg, at mark-blumberg@uiowa.edu.
Ads will be posted soon on our homepage: psychology.uiowa.edu
Ads will be posted soon on our homepage: psychology.uiowa.edu
Psychological and Brain Sciences | College of Liberal Arts and Sciences | The University of Iowa
Study the science behind behavior and cognition, learning and memory, and personality and emotion while developing research skills and preparing for success.
psychology.uiowa.edu
July 14, 2025 at 5:34 PM
Two faculty positions in my department this year. Please spread the word! And don't hesitate to reach out if you want to learn more.
Our study on the impact of altered serotonin (5-HT) signalling on the developing sensory cortex is now live at Nature Comms.
We use longitudinal in vivo imaging of 5-HT and neural activity to show that this neuromodulator is buffered in early life to promote bottom-up instruction of sensory areas.
We use longitudinal in vivo imaging of 5-HT and neural activity to show that this neuromodulator is buffered in early life to promote bottom-up instruction of sensory areas.
June 6, 2025 at 9:34 AM
Our study on the impact of altered serotonin (5-HT) signalling on the developing sensory cortex is now live at Nature Comms.
We use longitudinal in vivo imaging of 5-HT and neural activity to show that this neuromodulator is buffered in early life to promote bottom-up instruction of sensory areas.
We use longitudinal in vivo imaging of 5-HT and neural activity to show that this neuromodulator is buffered in early life to promote bottom-up instruction of sensory areas.
Reposted by Butt Lab - Oxford
Save the date!
We're organising a workshop on Data Sharing on the 10th of February at Guy's Campus (KCL)! All you need to know to make your datasets open to the public + engaging in open science practices.
More details to come soon — stay tuned!
We're organising a workshop on Data Sharing on the 10th of February at Guy's Campus (KCL)! All you need to know to make your datasets open to the public + engaging in open science practices.
More details to come soon — stay tuned!
January 9, 2025 at 1:38 PM
Save the date!
We're organising a workshop on Data Sharing on the 10th of February at Guy's Campus (KCL)! All you need to know to make your datasets open to the public + engaging in open science practices.
More details to come soon — stay tuned!
We're organising a workshop on Data Sharing on the 10th of February at Guy's Campus (KCL)! All you need to know to make your datasets open to the public + engaging in open science practices.
More details to come soon — stay tuned!
Reposted by Butt Lab - Oxford
Congratulations to Gabriel! @interneuron.bsky.social
January 7, 2025 at 2:49 PM
Congratulations to Gabriel! @interneuron.bsky.social
Reposted by Butt Lab - Oxford
Well done Ivan! @interneuron.bsky.social
January 8, 2025 at 9:43 AM
Well done Ivan! @interneuron.bsky.social
Reposted by Butt Lab - Oxford
This sounds interesting... definitely one to check out.
Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus - Nature Neuroscience
Microglia are proposed to have a role in brain development through synaptic engulfment and paracrine signaling. O’Keeffe et al. show that certain neurodevelopmental processes attributed to microglia c...
www.nature.com
January 6, 2025 at 7:09 PM
This sounds interesting... definitely one to check out.
Reposted by Butt Lab - Oxford
Fast-spike interneurons in visual cortical layer 5: Heterogeneous response properties are related to thalamocortical connectivity
Some L5 INT with strong input from LGN and visual responses more similar to L4 INT than those receiving little direct LGN input.
www.jneurosci.org/content/earl...
Some L5 INT with strong input from LGN and visual responses more similar to L4 INT than those receiving little direct LGN input.
www.jneurosci.org/content/earl...
Fast-spike interneurons in visual cortical layer 5: Heterogeneous response properties are related to thalamocortical connectivity
Layer 4 of rabbit V1 contains fast-spiking GABAergic interneurons (suspected inhibitory interneurons, SINs) that receive potent synaptic input from the LGN and generate fast, local feed-forward inhibi...
www.jneurosci.org
December 15, 2024 at 8:47 PM
Fast-spike interneurons in visual cortical layer 5: Heterogeneous response properties are related to thalamocortical connectivity
Some L5 INT with strong input from LGN and visual responses more similar to L4 INT than those receiving little direct LGN input.
www.jneurosci.org/content/earl...
Some L5 INT with strong input from LGN and visual responses more similar to L4 INT than those receiving little direct LGN input.
www.jneurosci.org/content/earl...
We did this. Beautiful work from the 🦋less Gabriel Ocana-Santero & team. More to follow soon but state-dependent neuromodulation is coming to developmental neuroscience in a big way 🧠🧪
Perinatal serotonin signalling dynamically influences the development of cortical GABAergic circuits with consequences for lifelong sensory encoding https://www.biorxiv.org/content/10.1101/2024.12.13.628340v1
December 14, 2024 at 2:35 PM
We did this. Beautiful work from the 🦋less Gabriel Ocana-Santero & team. More to follow soon but state-dependent neuromodulation is coming to developmental neuroscience in a big way 🧠🧪
Reposted by Butt Lab - Oxford
Neuroscience students asked us to teach a PRACTICAL course on experimental methods, and it is now on YouTube!
Please like and repost to help us get the word out!
www.youtube.com/playlist?lis...
Lecture 1: Signals and data acquisition
Focusing on hardware, digital/analog I/O, synchronization
🧵
Please like and repost to help us get the word out!
www.youtube.com/playlist?lis...
Lecture 1: Signals and data acquisition
Focusing on hardware, digital/analog I/O, synchronization
🧵
Neuroscience methods - YouTube
Nanocourse: Approaches to Study Neural Circuits This course was taught by Anita Autry, Tiago Gonçalves, and Luke Sjulson at Albert Einstein College of Medici...
www.youtube.com
December 13, 2024 at 11:33 AM
Neuroscience students asked us to teach a PRACTICAL course on experimental methods, and it is now on YouTube!
Please like and repost to help us get the word out!
www.youtube.com/playlist?lis...
Lecture 1: Signals and data acquisition
Focusing on hardware, digital/analog I/O, synchronization
🧵
Please like and repost to help us get the word out!
www.youtube.com/playlist?lis...
Lecture 1: Signals and data acquisition
Focusing on hardware, digital/analog I/O, synchronization
🧵
Reposted by Butt Lab - Oxford
A toolbox for ablating excitatory and inhibitory synapses
elifesciences.org
December 7, 2024 at 12:45 PM
Our 2nd new Doctor in as many days! Many congratulations to Gabi on the successful defence of his thesis (in vivo 5-HT in neurodevelopment; preprint out soon!). Huge thanks to the 🦋less, elite examining team of Oscar Marin & Colin Akerman, also co-PI Trevor Sharp and Serotonin & Beyond @ec.europa.eu
December 5, 2024 at 4:22 PM
Our 2nd new Doctor in as many days! Many congratulations to Gabi on the successful defence of his thesis (in vivo 5-HT in neurodevelopment; preprint out soon!). Huge thanks to the 🦋less, elite examining team of Oscar Marin & Colin Akerman, also co-PI Trevor Sharp and Serotonin & Beyond @ec.europa.eu
Reposted by Butt Lab - Oxford
NEW DOCTOR from the lab, Antara Majumdar🥳 🍾 thanks to @kerrywalker.bsky.social @jpassecker.bsky.social for examination & 2nd supervisor @interneuron.bsky.social. Here is Antara's preprint, came out right around the US election and X being deserted: www.biorxiv.org/content/10.1...
December 4, 2024 at 1:26 PM
NEW DOCTOR from the lab, Antara Majumdar🥳 🍾 thanks to @kerrywalker.bsky.social @jpassecker.bsky.social for examination & 2nd supervisor @interneuron.bsky.social. Here is Antara's preprint, came out right around the US election and X being deserted: www.biorxiv.org/content/10.1...
Reposted by Butt Lab - Oxford
Looking for an escape over the holiday?
@meikeesther.bsky.social and I published a ViewPoint looking at the intersection of Developmental and Systems Neuroscience titled “More Than a Small Brain: The Importance of Studying Neural Function during Development”
www.jneurosci.org/content/44/4...
@meikeesther.bsky.social and I published a ViewPoint looking at the intersection of Developmental and Systems Neuroscience titled “More Than a Small Brain: The Importance of Studying Neural Function during Development”
www.jneurosci.org/content/44/4...
More Than a Small Brain: The Importance of Studying Neural Function during Development
The nervous system contains complex circuits comprising thousands of cell types and trillions of connections. Here, we discuss how the field of “developmental systems neuroscience” combines the molecu...
www.jneurosci.org
November 27, 2024 at 6:48 PM
Looking for an escape over the holiday?
@meikeesther.bsky.social and I published a ViewPoint looking at the intersection of Developmental and Systems Neuroscience titled “More Than a Small Brain: The Importance of Studying Neural Function during Development”
www.jneurosci.org/content/44/4...
@meikeesther.bsky.social and I published a ViewPoint looking at the intersection of Developmental and Systems Neuroscience titled “More Than a Small Brain: The Importance of Studying Neural Function during Development”
www.jneurosci.org/content/44/4...
Reposted by Butt Lab - Oxford
A huge pleasure to repost this announcement - over 40 students have graduated from our fantastic @sussexneuro.bsky.social PhD programme, and each year brings new perspectives and opportunities for both the new joiners and ourselves as their hosts. Do consider applying!
Our Sussex Neuroscience 4-year PhD Programme is open for applications! Deadline Jan 13th, for Sept 2025 entry. Brilliant community of students and supervisors, and a choice of >60 labs for rotations- come and join us by the sea! www.sussex.ac.uk/research/cen...
Sussex Neuroscience 4-year PhD Programme : PhD Programmes in Neuroscience : Sussex Neuroscience : University of Sussex
www.sussex.ac.uk
November 27, 2024 at 5:06 PM
A huge pleasure to repost this announcement - over 40 students have graduated from our fantastic @sussexneuro.bsky.social PhD programme, and each year brings new perspectives and opportunities for both the new joiners and ourselves as their hosts. Do consider applying!
Reposted by Butt Lab - Oxford
We are recruiting a PhD student at the Brain, Body, and Self Lab, Department of Neuroscience, Karolinska Institutet. Learn more and apply here: kidoktorand.varbi.com/en/what:job/...
Doctoral (PhD) student position in Cognitive Neuroscience
Do you want to contribute to top quality medical research? To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individu
kidoktorand.varbi.com
November 26, 2024 at 8:53 AM
We are recruiting a PhD student at the Brain, Body, and Self Lab, Department of Neuroscience, Karolinska Institutet. Learn more and apply here: kidoktorand.varbi.com/en/what:job/...
Reposted by Butt Lab - Oxford
Neuroscientists! A key message from the ALBA Network
Please help us spread the word and share this with your network!!!
Nominate (self-n allowed) a mid-career neuroscientist (5+ years post-PhD) for the ALBA-Roche Research Prize for Excellence in Neuroscience!
🔎http://loom.ly/_EvQvm4
🗓️20 January 2025
Please help us spread the word and share this with your network!!!
Nominate (self-n allowed) a mid-career neuroscientist (5+ years post-PhD) for the ALBA-Roche Research Prize for Excellence in Neuroscience!
🔎http://loom.ly/_EvQvm4
🗓️20 January 2025
November 26, 2024 at 11:53 AM
Neuroscientists! A key message from the ALBA Network
Please help us spread the word and share this with your network!!!
Nominate (self-n allowed) a mid-career neuroscientist (5+ years post-PhD) for the ALBA-Roche Research Prize for Excellence in Neuroscience!
🔎http://loom.ly/_EvQvm4
🗓️20 January 2025
Please help us spread the word and share this with your network!!!
Nominate (self-n allowed) a mid-career neuroscientist (5+ years post-PhD) for the ALBA-Roche Research Prize for Excellence in Neuroscience!
🔎http://loom.ly/_EvQvm4
🗓️20 January 2025
Reposted by Butt Lab - Oxford
November 23, 2024 at 8:29 AM
Reposted by Butt Lab - Oxford
Dive into our latest findings on this powerful structure here: “The claustrum is critical for maintaining working memory” biorxiv.org/cgi/content/...
The claustrum is critical for maintaining working memory information
Working memory (WM) enables the mammalian brain to temporarily store and manipulate information, supporting cognitive tasks and communication processes. Rather than depending on a single specialized a...
biorxiv.org
November 22, 2024 at 7:50 AM
Dive into our latest findings on this powerful structure here: “The claustrum is critical for maintaining working memory” biorxiv.org/cgi/content/...
Reposted by Butt Lab - Oxford
**We are recruiting**
Seeking a postdoc to work on a Wellcome-funded cohort study focusing on social-cognitive processing in typically developing children and adolescents (aged 8-18 years) and children and adolescents with 22q11.1 deletion syndrome.
www.jobs.cam.ac.uk/job/49291/
Seeking a postdoc to work on a Wellcome-funded cohort study focusing on social-cognitive processing in typically developing children and adolescents (aged 8-18 years) and children and adolescents with 22q11.1 deletion syndrome.
www.jobs.cam.ac.uk/job/49291/
Research Assistant/Research Associate (Fixed Term) - Job Opportunities - University of Cambridge
Research Assistant/Research Associate (Fixed Term) in the Department of Psychology at the University of Cambridge.
www.jobs.cam.ac.uk
November 21, 2024 at 11:24 AM
**We are recruiting**
Seeking a postdoc to work on a Wellcome-funded cohort study focusing on social-cognitive processing in typically developing children and adolescents (aged 8-18 years) and children and adolescents with 22q11.1 deletion syndrome.
www.jobs.cam.ac.uk/job/49291/
Seeking a postdoc to work on a Wellcome-funded cohort study focusing on social-cognitive processing in typically developing children and adolescents (aged 8-18 years) and children and adolescents with 22q11.1 deletion syndrome.
www.jobs.cam.ac.uk/job/49291/
Reposted by Butt Lab - Oxford
Fantastic work by @peruhlen.bsky.social and @kanashigeaki.bsky.social, with a beautiful cover in Science that tells it all!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
November 21, 2024 at 9:26 PM
Fantastic work by @peruhlen.bsky.social and @kanashigeaki.bsky.social, with a beautiful cover in Science that tells it all!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
This made for an interesting read over breakfast: science publishing and behaviour all crammed into 1 article.
‘Mad egghead’ who built a mouse utopia
www.theguardian.com/science/2024...
‘Mad egghead’ who built a mouse utopia
www.theguardian.com/science/2024...
The ‘mad egghead’ who built a mouse utopia
The long read: John Calhoun designed an apartment complex for mice, to examine the effects of overcrowding. It was hailed as a groundbreaking study of social breakdown, but is largely forgotten. So wh...
www.theguardian.com
November 21, 2024 at 8:44 AM
This made for an interesting read over breakfast: science publishing and behaviour all crammed into 1 article.
‘Mad egghead’ who built a mouse utopia
www.theguardian.com/science/2024...
‘Mad egghead’ who built a mouse utopia
www.theguardian.com/science/2024...