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immunolcellbiol.bsky.social
ICB - the journal
@immunolcellbiol.bsky.social
Cutting edge original research, provocative and exciting reviews and News and Commentary coverage on Immunology and Cell Biology
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So many good reasons to publish in ICB!
July's featured article from our exchange with @discovimmunol.bsky.social investigates the immunomodulatory capacity of various arginine-related metabolites.

academic.oup.com/discovimmuno...
July 18, 2025 at 8:33 AM
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This is a great new study showing in Crohn’s disease, aphthous ulcers trigger immune responses via bacterial uptake, not dysbiosis

This is part of the article exchange between the BSI's @discovimmunol.bsky.social and the @immunolcellbiol.bsky.social
This month’s article exchange with @immunolcellbiol.bsky.social:

New study shows that in Crohn’s disease, aphthous ulcers trigger immune responses via bacterial uptake, not dysbiosis.

Peyer’s patches may be the ignition site 🧬

Read here: doi.org/10.1111/imcb...

#Crohns #Immunology
June 20, 2025 at 10:30 AM
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This month’s article exchange with @immunolcellbiol.bsky.social:

New study shows that in Crohn’s disease, aphthous ulcers trigger immune responses via bacterial uptake, not dysbiosis.

Peyer’s patches may be the ignition site 🧬

Read here: doi.org/10.1111/imcb...

#Crohns #Immunology
June 20, 2025 at 9:16 AM
What can we learn about airway resident memory T cells from pig models? Plenty! Find out more in this month's @discovimmunol.bsky.social Outstanding Article
June 19, 2025 at 8:48 AM
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For this month’s article exchange with @immunolcellbiol.bsky.social: Genetic analysis causally links 22 immune cell types to PCOS. Blood metabolites mediate several effects, offering new insight into how immunity and metabolism shape disease.

🔗 doi.org/10.1111/imcb...
May 22, 2025 at 11:15 AM
May's featured article in our exchange with @discovimmunol.bsky.social reveals altered spatial distribution of ILCs in #endometriosis and suggests the primary role of uterine ILC3 may be endometrial repair and regeneration.
May 22, 2025 at 10:33 AM
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Our @immunolcellbiol.bsky.social "Highlights of 2024: Germinal Centers" is now out. Led by Theresa Pankhurst, we discuss some (there's never enough space for all!) neat germinal centre papers that were published in 2024, and whose findings are moving the field forward. doi.org/10.1111/imcb...
<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library
In this article for the Highlights of 2024 series, we review the latest advances in the biology of the germinal center response. These discoveries provide key insights into germinal center function a...
doi.org
May 22, 2025 at 12:13 AM
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For this month's article exchange with @immunolcellbiol.bsky.social we're highlighting "Notch dependent chromatin remodelling enables Gata3 binding and drives lineage specific CD8+ T cell function."

A study on how Notch signalling primes antiviral CD8+ T cell responses.

📖 doi.org/10.1111/imcb...
<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library
This study examines how Notch signaling conditions the genome landscape within activated CD8+ T cells in such a way to alter the binding pattern of transcription factors such as Gata3. This Notch dep...
doi.org
April 24, 2025 at 2:21 PM
Our April article exchange with @discovimmunol.bsky.social features a study on the relative contribution of CD28 and TCR signals on human naive and memory T cells.
academic.oup.com/discovimmuno...
April 24, 2025 at 8:38 AM
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"Your career is more than just your technical expertise—the skills, interests and motivations that make you unique, both inside and outside of research, can shape your path in unexpected ways."

Dr Amy Wilson from @ocrfaustralia.bsky.social reflects on moving into a research advisor role
<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library
Amy Wilson, a Research Advisor for the Ovarian Cancer Research Foundation (OCRF) and an Honorary Research Associate at the Hudson Institute of Medical Research, began her career as a postdoctoral res....
onlinelibrary.wiley.com
March 21, 2025 at 2:37 AM
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For this month's article exchange with
@immunolcellbiol.bsky.social, we're highlighting 'Refining bone marrow ablation and reconstitution in mice.' by Penny Hawkins, James Dooley, Jessica Rodda and Colin Gilbert.

🔎 Read here: doi.org/10.1111/imcb.12847
<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library
Bone marrow ablation and reconstitution are commonly used procedures in research that are often associated with significant suffering for the animals involved, classified as ‘severe’, Category E or C...
onlinelibrary.wiley.com
March 20, 2025 at 5:15 PM
To what extent do different practices of microbial exposure affect resulting mouse phenotypes? March's Outstanding article from @discovimmunol.bsky.social shows a side-by-side comparison, enhancing understanding of naturalisation model setups and effects on the gut barrier and immune system
March 20, 2025 at 7:40 AM
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Are you ready for it?

"Highlights of 2024: γδ T cells and bad blood"

A summary of the emerging regulatory and effector roles of #gdTcells in #sepsis.

And it may also contain a few Taylor Swift references. More than 50 in fact.

Thank you so much @immunolcellbiol.bsky.social for playing along!
<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library
In this manuscript for the “Highlights of 2024” series, this is me trying to summarize recent discoveries regarding the emerging regulatory and effector roles of γδ T cells during sepsis, both in hum....
onlinelibrary.wiley.com
March 10, 2025 at 12:29 AM
From pipettes to playdates! @rhea-longley.bsky.social et al. share challenges and successes from establishing a parent support group in a research setting.
<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library
In this article, we discuss the conceptualization, formation and management of our workplace Parents Group. We honestly reflect on both our successes and challenges. Graphic from Vivienne Samson (age....
onlinelibrary.wiley.com
March 7, 2025 at 4:53 AM
Our new special feature is out now! From reflections on starting a parents group for researchers to a case study on Indigenous student engagement in science, this special feature amplifies intersectional discussions on diversity, equity, and inclusion in healthcare and STEMM. bit.ly/41JpXKa
March 7, 2025 at 3:25 AM
This article from our upcoming special feature on Advancing Equity and Inclusion in Healthcare highlights the work of Immunologists for Gender Equity (IgEquity), a trainee-led organisation at @immunox.bsky.social. #InternationalWomensDay
<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library
This article highlights the work of our trainee-led organization, Immunologists for Gender Equity (IgEquity), which addresses gender inequities in Immunology through initiatives focused on community ....
onlinelibrary.wiley.com
March 5, 2025 at 11:38 PM
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Our paper is finally out in @immunolcellbiol.bsky.social, think that transcription factor expression is all that? Well not if the genome is not prepared in a way to allow binding: here is a short 🧵1/
March 1, 2025 at 2:34 AM
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For this month's article exchange with @immunolcellbiol.bsky.social, we're highlighting 'Exploring the dynamics of T-cell responses: a combined approach using EdU incorporation and proliferation dye dilution assay' by @jfreenvanheeren.bsky.social and colleagues

🔎 Read here: doi.org/10.1111/imcb...
bsky.app
February 20, 2025 at 2:11 PM
Obesity is associated with increased susceptibility to infection, which may be due to obesity-induced immune dysregulation. The latest article exchange highlight from @discovimmunol.bsky.social looks at dendritic cell responses to Sendai Virus in a mouse model of diet-induced obesity.
February 20, 2025 at 6:14 AM
Self-reactive B cells are increased in all major stages of peripheral development in Sjögren's disease. This study from Lee et al. suggests that depleting self-reactive B cells based on B cell receptor specificity would be more efficient than targeting developmental stage in Sjögren's disease.
<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library
In this article, we identify self-reactive peripheral blood B cells in Sjögren's disease through a single-cell culture system. We find 2- to 10-fold increased frequencies of self-reactive B cells dur...
onlinelibrary.wiley.com
February 18, 2025 at 3:57 AM
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Thanks @immunolcellbiol.bsky.social for inviting Menno and I to write this commentary about the @bogunoviclab.bsky.social paper in @nature.com on monoallelic allele expression in inborn errors of immunity
Monash Immunology and
Erasmus MC #immunosky
doi.org/10.1111/imcb...
doi.org
February 6, 2025 at 7:26 AM
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If any American immunologists want to write an op-ed for @immunolcellbiol.bsky.social on the impact of the new executive orders, please contact me
February 3, 2025 at 10:05 AM
Modeling the response to interleukin-21 to inform natural killer cell immunotherapy
<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library
In this study, we investigated multiple cytokine combinations to boost natural killer (NK) cell proliferation as well as effector functions of proliferated NK cells against hepatocellular carcinoma a...
onlinelibrary.wiley.com
February 3, 2025 at 2:41 AM
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Also, the submission and editorial experience with @immunolcellbiol.bsky.social was fantastic, highly efficient, very professional, and yes I am an #AusNZSocImmunol member, but if you are looking for somewhere to publish #immunologyiscool work, can't recommend highly enough.
January 30, 2025 at 11:01 PM