Immunological Proteome Resource
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immpres.bsky.social
Immunological Proteome Resource
@immpres.bsky.social
ImmPRes is an open access public resource created to provide an in-depth, high quality, quantitative map of the immune cell proteomes. Created by Alejandro Brenes @ajbrenes.com

http://immpres.co.uk/
Reposted by Immunological Proteome Resource
I am overjoyed to present our latest paper on Autophagy in CD8 Tcells!
www.nature.com/articles/s41...
It was, as all ‘sciencing’ is, a huge team effort.

I will try to do it some justice in the following thread 😊 1/n
@cantrell-lab.bsky.social @immpres.bsky.social @ajmhowden.bsky.social
Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells - Nature Immunology
Sinclair et al. combine quantitative proteomics and an autophagy flux reporter to map autophagy substrates and triggers during CD8 T cell differentiation. Proteins degraded and fueled by autophagy in ...
www.nature.com
March 1, 2025 at 11:18 AM
We have new exciting data coming your way soon. New murine T cell and B cell datasets. Keep tuned!

This means ImmPRes will have included 23 murine proteomic datasets!
February 10, 2025 at 9:52 AM
Reposted by Immunological Proteome Resource
Data is on ImmPRes @immpres.bsky.social and full paper on @elife.bsky.social elifesciences.org/articles/53725

This was an old dataset so it is DDA based LFQ with 8 fractions. Coverage was good but it has the normal issues of label free DDA
Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell acti...
Myc-dependent induction of amino acid transporter expression in response to T cell receptor activation is essential to enable T cell proteome remodelling upon immune activation.
elifesciences.org
October 3, 2023 at 10:10 AM
📢 we have a schedule maintenance. ImmPRes will be down on the 27th and expect to be back online by the 29th.
September 27, 2023 at 9:53 AM
🧪🧪 The Immunological Proteome Resource is now on Bluesky as well.

ImmPRes is an open access resource created to provide an in-depth, high quality, quantitative map of the immuno proteome. It integrates immune cell proteomic data generated by quantitative mass-spectrometry.

#immunology #proteomics
September 22, 2023 at 2:46 PM