HighlanderLab
highlanderlab.bsky.social
HighlanderLab
@highlanderlab.bsky.social
Research on managing and improving populations at
@RoslinInstitute & @TheDickVet. Led by the chief Highlander @GregorGorjanc.
Reposted by HighlanderLab
This is a joint work with @highlanderlab.bsky.social @gregorgorjanc.bsky.social

The software is available in github and will also be on CRAN as soon as the screening is cleared.

github.com/HighlanderLa...
GitHub - HighlanderLab/RandPedPCA: Principal Component Analysis of Pedigree Relationship Matrix via Randomized SVD
Principal Component Analysis of Pedigree Relationship Matrix via Randomized SVD - HighlanderLab/RandPedPCA
github.com
March 19, 2025 at 12:55 PM
Reposted by HighlanderLab
Lastly I gave a short course on Stochastic simulations of breeding programmes with AlphaSimR - a teaser for our free on-line course www.edx.org/learn/animal...
EdinburghX: Breeding Programme Modelling with AlphaSimR | edX
Breeding programmes are key to the genetic improvement of plant varieties and animal breeds used in agriculture. This unique course shows how to model an existing or new breeding programme and the eva...
www.edx.org
February 3, 2025 at 10:57 AM
Reposted by HighlanderLab
I presented the work of Letícia Lara on Evaluation of selective breeding programme designs for black soldier fly larvae body weight (with María Martínez Castillero, Thiago Oliveira, Ivan Pocrnić, Jana Obšteter)
February 3, 2025 at 10:57 AM
Reposted by HighlanderLab
Jana Obšteter presented the work of Laura Strachan on Optimizing pedigree reconstruction and patriline determination in honeybees (with Jernej Bubnič and Janez Presern)
February 3, 2025 at 10:57 AM
Reposted by HighlanderLab
Irene de Carlos Fernández presented her work on Modelling the Impact of Non-Native Honey Bee Importation on Native Apis mellifera mellifera Populations (with Laura Strachan, Grace McCormack, Jana Obšteter)
February 3, 2025 at 10:57 AM
Reposted by HighlanderLab
Last week some of us attended the 1st EAAP - European Federation of Animal Science Insect Genetics Workshop, which was organised with InsectIMP CA22140 COST Action action by Gertje Petersen and Jana Obšteter. We presented
February 3, 2025 at 10:57 AM
HighlanderLab at PopGroup58 in Sheffield! It’s always interesting to attend the highly diverse set of talks and posters on population genetics and associated fields at the PopGroup conference. This year it was hosted by the University of Sheffield. We contributed with two talks and four posters.
January 17, 2025 at 6:15 AM
Reposted by HighlanderLab
Exciting PhD opportunity to join us at Roslin/Edinburgh and work with the largest whole-genome sequencing dataset in selective breeding. www.findaphd.com/phds/project...
EASTBIO: MegaPhase: Pedigree phasing and imputation for mega-scale whole genome sequence data at University of Edinburgh on FindAPhD.com
PhD Project - EASTBIO: MegaPhase: Pedigree phasing and imputation for mega-scale whole genome sequence data at University of Edinburgh, listed on FindAPhD.com
www.findaphd.com
November 29, 2024 at 10:12 AM
Reposted by HighlanderLab
A new pre-print “Robust Optimal Contribution Selection” led by Josh Fogg. We show how to account for the uncertainty and correlation of estimated breeding values in the optimal contribution selection problem: arxiv.org/abs/2412.02888
Robust Optimal Contribution Selection
Optimal contribution selection (OCS) is a selective breeding method that manages the conversion of genetic variation into genetic gain to facilitate short-term competitiveness and long-term sustainabi...
arxiv.org
December 10, 2024 at 7:40 AM
Reposted by HighlanderLab
AlphaSimR course edin.ac/3wfGSEj Week 2:
It’s time for trait simulation - one of the key reasons we developed AlphaSimR - to study the principles of quantitative genetics and selective breeding. Here, we show the outline of such a simulation, ...
December 16, 2024 at 11:43 AM
Reposted by HighlanderLab
📺 In our seminar last week Dr Hannes Becher from
@highlanderlab.bsky.social spoke about "Assembly-free estimation of population parameters using single-individual k-mer spectra". 🧬💻
If you missed the seminar, the recording is now available on our YouTube channel 👇
youtu.be/-wHqNbdpEog?...
🧪
Hannes Becher: Assembly-free estimation of population parameters using k-mer spectra
YouTube video by CGDG - Computational Genetics Discussion Group
youtu.be
December 2, 2024 at 10:00 AM
Reposted by HighlanderLab
Please share: Exciting post for a Quantitative Genetics and Breeding scientist to
to develop and implement a breeding programme for artemia - a Knowledge Transfer Partnership between Aquanzo and Roslin Institute supported by KTN/KTP InnovateUK elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
April 10, 2024 at 11:00 AM
Reposted by HighlanderLab
AlphaSimR course edin.ac/3wfGSEj Week 2: Continuing work with genomes and genotype variation, focusing on loci. We extract genotypes from a population, calculate and plot allele frequencies, and calculate and plot linkage-disequilibrium.
March 11, 2024 at 10:13 AM
We just completed Armidale Genetics Summer Course on “Theory and Tools for Designing Breeding Programs of Animals and Plants”.

jvanderw.une.edu.au/aabc2024.htm
February 12, 2024 at 4:33 AM
New pre-print: "A framework for simulating GxE interaction using multiplicative models" by Jon Bancic, @gregorgorjanc.bsky.social and Daniel Tolhurst
. researchsquare.com/article/rs-3...
February 2, 2024 at 2:31 AM
We welcome Alex Lipka for a sabbatical at our lab at Roslin Institute. He took an obligatory photo with the founder of our vet school:)
January 11, 2024 at 2:01 PM
Reposted by HighlanderLab
If you are looking for a PhD involving topics mentioned in this thread here is an opportunity to join us findaphd.com/phds/project...
Response to multiple generations of simple selective breeding (top 25%). No new mutations here so heritability drops to zero and response hits diminishing returns. Switch to random mating in generation 15.
January 2, 2024 at 11:53 AM
New pre-print: “Plant breeding simulations with AlphaSimR” led by Jon Bancic in collaboration with Philip Greenspoon, Chris Gaynor, and @gregorgorjanc.bsky.social www.biorxiv.org/content/10.1... A short thread with highlights.
December 31, 2023 at 3:02 PM