Henry Le
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henryhle.bsky.social
Henry Le
@henryhle.bsky.social
Metabolomics/Lipidomics/Proteomics, Bioactivity, Natural Products, Microbiome Science || Grad & Post-Doc @Cornell || Links https://linktr.ee/henrychembio
Science has identified determinant of allergies, but for the first time, @jamieblum.bsky.social et al. identifies determinants of tolerance. www.biorxiv.org/content/10.1...
Discovery and characterization of dietary antigens in oral tolerance
Food antigens elicit immune tolerance through the action of regulatory T cells (Tregs) in the intestine. Although antigens that trigger common food allergies are known, the epitopes that mediate toler...
www.biorxiv.org
January 27, 2025 at 5:57 AM
Reposted by Henry Le
#YearInReview A new understanding of how ketosis is linked to body weight regulation: https://buff.ly/3ZOkoId
December 27, 2024 at 6:00 PM
Reposted by Henry Le
Maybe a good time to plug this awesome book edited by former PhD students Howard Hang (Scripps), Matt Pratt (USC), Jenn Prescher (UC Irvine), featuring chapters by leaders in the field including @jeremybaskin.bsky.social and a forward by yours truly.
December 5, 2024 at 1:52 PM
Reposted by Henry Le
Fat tissue retains a ‘memory’ of obesity through cellular transcriptional and epigenetic changes that persist after weight loss, which might increase the chance of regaining weight, according to a study in Nature. go.nature.com/48ZTVfg
November 19, 2024 at 3:04 PM
Reposted by Henry Le
Cool paper from Cravatt lab: Chemical tools to expand the ligandable proteome: Diversity-oriented synthesis-based photoreactive stereoprobes: www.cell.com/cell-chemica...
Chemical tools to expand the ligandable proteome: Diversity-oriented synthesis-based photoreactive stereoprobes
Many human proteins lack chemical probes and are even considered undruggable. Ogasawara et al. describe diversity-oriented synthesis-inspired photoreactive small molecules (photo-stereoprobes) and the...
www.cell.com
November 19, 2024 at 2:02 AM
Reposted by Henry Le
All, please check out our Sarafan ChEM-H institute feed here @stanford-chemh.bsky.social. For new folks, ChEM-H stands for “Chemistry, Engineering and Medicine for Human Health”. For more about our research mission, faculty scholars and fellows, and training programs, see: chemh.stanford.edu
Sarafan ChEM-H
Bridging chemistry, engineering, biology, and medicine to improve human health
chemh.stanford.edu
November 18, 2024 at 5:28 PM
Reposted by Henry Le
Too often we spend only two weeks choosing a problem and then many years trying solving it, but this limits our potential impact.
A must read for PhD students: Problem choice and decision trees in science and engineering.
pubmed.ncbi.nlm.nih.gov/38608651/
November 17, 2024 at 5:35 PM
November 16, 2024 at 4:51 AM